OA11084A - 2-Amino--6-(2-substituted-4-phenoxy)-substituted- pyridines - Google Patents
2-Amino--6-(2-substituted-4-phenoxy)-substituted- pyridines Download PDFInfo
- Publication number
- OA11084A OA11084A OA9900173A OA9900173A OA11084A OA 11084 A OA11084 A OA 11084A OA 9900173 A OA9900173 A OA 9900173A OA 9900173 A OA9900173 A OA 9900173A OA 11084 A OA11084 A OA 11084A
- Authority
- OA
- OAPI
- Prior art keywords
- alkyl
- formula
- nmr
- disease
- nitrogen
- Prior art date
Links
- CMCVDHBBWOUHOU-UHFFFAOYSA-N Cc1cc(OCc2ccccc2)cc(C)c1B(O)O Chemical compound Cc1cc(OCc2ccccc2)cc(C)c1B(O)O CMCVDHBBWOUHOU-UHFFFAOYSA-N 0.000 description 1
- LXPOYZVSGGMEMK-UHFFFAOYSA-N Cc1cc(OCc2ccccc2)cc(C)c1Br Chemical compound Cc1cc(OCc2ccccc2)cc(C)c1Br LXPOYZVSGGMEMK-UHFFFAOYSA-N 0.000 description 1
- BYTJTXKQBSNGCL-UHFFFAOYSA-N Fc(cc(cc1)OCc2ccccc2)c1Br Chemical compound Fc(cc(cc1)OCc2ccccc2)c1Br BYTJTXKQBSNGCL-UHFFFAOYSA-N 0.000 description 1
- PQWKGFALWCOVTC-UHFFFAOYSA-N OB(c(ccc(OCc1ccccc1)c1)c1F)O Chemical compound OB(c(ccc(OCc1ccccc1)c1)c1F)O PQWKGFALWCOVTC-UHFFFAOYSA-N 0.000 description 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/73—Unsubstituted amino or imino radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Ophthalmology & Optometry (AREA)
- Hospice & Palliative Care (AREA)
- Diabetes (AREA)
- Rheumatology (AREA)
- Hematology (AREA)
- Addiction (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3753397P | 1997-02-10 | 1997-02-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| OA11084A true OA11084A (en) | 2002-03-15 |
Family
ID=21894849
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| OA9900173A OA11084A (en) | 1997-02-10 | 1999-08-06 | 2-Amino--6-(2-substituted-4-phenoxy)-substituted- pyridines |
Country Status (44)
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20010049379A1 (en) | 1997-08-27 | 2001-12-06 | Lowe John Adams | 2-aminopyridines containing fused ring substituents |
| AU765851B2 (en) * | 1998-06-03 | 2003-10-02 | Pfizer Products Inc. | 2-aminopyridines containing fused ring substituents as nitric oxide synthase inhibitors |
| TR200401803T2 (tr) * | 1998-08-11 | 2004-11-22 | Pfizer Products Inc. | NOS önleyicileri için yeni farmasötik kullanımlar. |
| SE9803710L (sv) | 1998-09-25 | 2000-03-26 | A & Science Invest Ab | Användning av vissa substanser för behandling av nervrotsskador |
| US7115557B2 (en) | 1998-09-25 | 2006-10-03 | Sciaticon Ab | Use of certain drugs for treating nerve root injury |
| HUP0200163A3 (en) * | 1999-02-25 | 2002-11-28 | Pfizer Prod Inc | 2-aminopyridines containing fused ring substituents, pharmaceutical compositions containing them and their use |
| FR2812635B1 (fr) * | 2000-08-01 | 2002-10-11 | Aventis Pharma Sa | Nouveaux composes heterocycliques, preparation et utilisation comme medicaments notamment comme anti- bacteriens |
| GB0019006D0 (en) * | 2000-08-04 | 2000-09-20 | Astrazeneca Ab | Novel compounds |
| US20030045449A1 (en) * | 2001-08-15 | 2003-03-06 | Pfizer, Inc. | Pharmaceutical combinations for the treatment of neurodegenerative diseases |
| US20030232739A1 (en) * | 2001-08-15 | 2003-12-18 | Pfizer Inc. | Pharmaceutical combinations comprising a NOS inhibitor and an NMDA receptor antagonist |
| DOP2002000467A (es) * | 2001-10-10 | 2003-04-15 | Pfizer Prod Inc | 2-amino-6 (fenilo sustituido en las posiciones 2,4,5)-piridinas |
| US6803470B2 (en) | 2001-10-10 | 2004-10-12 | Pfizer Inc | 2-amino-6-(2,4,5-substituted-phenyl)-pyridines |
| US7045652B2 (en) | 2002-07-03 | 2006-05-16 | Pfizer Inc | Processes for preparing substituted aryl boronic acids |
| US20040092741A1 (en) * | 2002-11-08 | 2004-05-13 | Pfizer Inc | Substituted pyridines via boronic acid coupling |
| WO2005007627A1 (ja) * | 2003-07-18 | 2005-01-27 | Nihon Nohyaku Co., Ltd. | フェニルピリジン誘導体、その中間体及びこれを有効成分とする除草剤 |
| EP1850838A2 (en) * | 2005-02-21 | 2007-11-07 | Proximagen Ltd. | Inhibition or treatment of dyskinesia |
| GB0607196D0 (en) * | 2006-04-11 | 2006-05-17 | Prosidion Ltd | G-protein coupled receptor agonists |
| WO2008080938A1 (en) * | 2006-12-28 | 2008-07-10 | Basf Se | Use 2-substituted pyridines for cancer treatment |
| UA105182C2 (ru) | 2008-07-03 | 2014-04-25 | Ньюрексон, Інк. | Бензоксазины, бензотиазины и родственные соединения, которые имеют ингибирующую nos активность |
| JP6387023B2 (ja) | 2013-02-28 | 2018-09-05 | ティウムバイオ カンパニー、リミテッドＴｉｕｍＢｉｏ Ｃｏ．， Ｌｔｄ． | 三環式化合物およびその使用 |
| AU2014346483B2 (en) * | 2013-11-07 | 2019-01-17 | The University Of Kansas | Biphenylamide derivative Hsp90 inhibitors |
| US10562858B2 (en) * | 2014-08-13 | 2020-02-18 | Meiji Seika Pharma Co., Ltd. | Crystalline anti-trichophyton agents and preparation process thereof |
| CN106265640B (zh) * | 2016-08-11 | 2019-05-14 | 吉林大学 | Appa在制备治疗糖尿病肾病药物中的应用 |
| CN108069831B (zh) * | 2018-01-25 | 2020-11-24 | 上海恩氟佳科技有限公司 | 一种合成2,3-二甲基-4-氟苯酚的方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0674627A1 (en) * | 1992-12-18 | 1995-10-04 | The Wellcome Foundation Limited | Pyrimidine, pyridine, pteridinone and indazole derivatives as enzyme inhibitors |
| EP0724570B1 (en) * | 1993-10-21 | 1999-03-03 | G.D. Searle & Co. | Amidino derivatives useful as nitric oxide synthase inhibitors |
| WO1996018616A1 (en) * | 1994-12-12 | 1996-06-20 | Merck & Co., Inc. | Substituted 2-aminopyridines as inhibitors of nitric oxide synthase |
| EP1471055A1 (en) * | 1996-03-29 | 2004-10-27 | Pfizer Inc. | 6-phenylpyridyl-2-amine derivatives |
-
1998
- 1998-01-29 SK SK1011-99A patent/SK101199A3/sk unknown
- 1998-01-29 JP JP53404898A patent/JP3505189B2/ja not_active Expired - Fee Related
- 1998-01-29 CN CNA031086047A patent/CN1515554A/zh active Pending
- 1998-01-29 UA UA99084543A patent/UA64740C2/uk unknown
- 1998-01-29 PT PT98900635T patent/PT958282E/pt unknown
- 1998-01-29 EA EA199900632A patent/EA003834B1/ru not_active IP Right Cessation
- 1998-01-29 YU YU35699A patent/YU35699A/sh unknown
- 1998-01-29 CN CN98802392A patent/CN1246848A/zh active Pending
- 1998-01-29 CA CA002277990A patent/CA2277990C/en not_active Expired - Fee Related
- 1998-01-29 CN CNA2004100073282A patent/CN1523015A/zh active Pending
- 1998-01-29 TR TR1999/01917T patent/TR199901917T2/xx unknown
- 1998-01-29 SI SI9830699T patent/SI0958282T1/xx unknown
- 1998-01-29 WO PCT/IB1998/000112 patent/WO1998034919A1/en active IP Right Grant
- 1998-01-29 AT AT98900635T patent/ATE271544T1/de not_active IP Right Cessation
- 1998-01-29 DK DK98900635T patent/DK0958282T3/da active
- 1998-01-29 KR KR10-1999-7007065A patent/KR100460399B1/ko not_active IP Right Cessation
- 1998-01-29 EP EP98900635A patent/EP0958282B1/en not_active Expired - Lifetime
- 1998-01-29 DE DE69825147T patent/DE69825147T2/de not_active Expired - Fee Related
- 1998-01-29 BR BR9811093-4A patent/BR9811093A/pt not_active Application Discontinuation
- 1998-01-29 PL PL98335161A patent/PL335161A1/xx unknown
- 1998-01-29 HU HU0000762A patent/HUP0000762A3/hu unknown
- 1998-01-29 AU AU55727/98A patent/AU744313B2/en not_active Ceased
- 1998-01-29 CZ CZ19992769A patent/CZ292135B6/cs not_active IP Right Cessation
- 1998-01-29 NZ NZ336623A patent/NZ336623A/xx unknown
- 1998-01-29 IL IL13089898A patent/IL130898A0/xx unknown
- 1998-01-29 NZ NZ518345A patent/NZ518345A/en unknown
- 1998-01-29 ES ES98900635T patent/ES2224354T3/es not_active Expired - Lifetime
- 1998-02-03 TW TW087101311A patent/TW458969B/zh not_active IP Right Cessation
- 1998-02-05 AP APAP/P/1998/001178A patent/AP833A/en active
- 1998-02-05 PE PE1998000082A patent/PE58599A1/es not_active Application Discontinuation
- 1998-02-06 MY MYPI98000488A patent/MY120976A/en unknown
- 1998-02-06 UY UY24881A patent/UY24881A1/es not_active Application Discontinuation
- 1998-02-09 ZA ZA9801017A patent/ZA981017B/xx unknown
- 1998-02-09 AR ARP980100551A patent/AR011117A1/es not_active Application Discontinuation
- 1998-02-09 DZ DZ980024A patent/DZ2414A1/xx active
- 1998-02-09 MA MA24958A patent/MA27676A1/fr unknown
- 1998-02-09 TN TNTNSN98024A patent/TNSN98024A1/fr unknown
- 1998-02-09 HN HN1998000030A patent/HN1998000030A/es unknown
- 1998-02-10 CO CO98006875A patent/CO4920225A1/es unknown
- 1998-02-10 PA PA19988446301A patent/PA8446301A1/es unknown
- 1998-02-10 HR HR60/037,533A patent/HRP980069A2/hr not_active Application Discontinuation
- 1998-02-11 GT GT199800032A patent/GT199800032A/es unknown
- 1998-07-31 US US09/127,158 patent/US20010007873A1/en not_active Abandoned
-
1999
- 1999-07-16 IS IS5118A patent/IS5118A/is unknown
- 1999-08-03 BG BG103633A patent/BG103633A/bg unknown
- 1999-08-06 OA OA9900173A patent/OA11084A/en unknown
- 1999-08-09 NO NO19993823A patent/NO314803B1/no unknown
-
2003
- 2003-02-20 US US10/371,357 patent/US20030162765A1/en not_active Abandoned
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