ZA981017B - 2-amino-6-(2-substituted-4-phenoxy)-substituted-pyridines. - Google Patents

2-amino-6-(2-substituted-4-phenoxy)-substituted-pyridines.

Info

Publication number
ZA981017B
ZA981017B ZA9801017A ZA981017A ZA981017B ZA 981017 B ZA981017 B ZA 981017B ZA 9801017 A ZA9801017 A ZA 9801017A ZA 981017 A ZA981017 A ZA 981017A ZA 981017 B ZA981017 B ZA 981017B
Authority
ZA
South Africa
Prior art keywords
substituted
pyridines
phenoxy
amino
Prior art date
Application number
ZA9801017A
Other languages
English (en)
Inventor
John Adams Lowe Iii
Jolanta Nowakowski
Robert Alfred Volkmann
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of ZA981017B publication Critical patent/ZA981017B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/73Unsubstituted amino or imino radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/02Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Ophthalmology & Optometry (AREA)
  • Hospice & Palliative Care (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Addiction (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA9801017A 1997-02-10 1998-02-09 2-amino-6-(2-substituted-4-phenoxy)-substituted-pyridines. ZA981017B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US3753397P 1997-02-10 1997-02-10

Publications (1)

Publication Number Publication Date
ZA981017B true ZA981017B (en) 1999-08-10

Family

ID=21894849

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9801017A ZA981017B (en) 1997-02-10 1998-02-09 2-amino-6-(2-substituted-4-phenoxy)-substituted-pyridines.

Country Status (44)

Country Link
US (2) US20010007873A1 (es)
EP (1) EP0958282B1 (es)
JP (1) JP3505189B2 (es)
KR (1) KR100460399B1 (es)
CN (3) CN1515554A (es)
AP (1) AP833A (es)
AR (1) AR011117A1 (es)
AT (1) ATE271544T1 (es)
AU (1) AU744313B2 (es)
BG (1) BG103633A (es)
BR (1) BR9811093A (es)
CA (1) CA2277990C (es)
CO (1) CO4920225A1 (es)
CZ (1) CZ292135B6 (es)
DE (1) DE69825147T2 (es)
DK (1) DK0958282T3 (es)
DZ (1) DZ2414A1 (es)
EA (1) EA003834B1 (es)
ES (1) ES2224354T3 (es)
GT (1) GT199800032A (es)
HN (1) HN1998000030A (es)
HR (1) HRP980069A2 (es)
HU (1) HUP0000762A3 (es)
IL (1) IL130898A0 (es)
IS (1) IS5118A (es)
MA (1) MA27676A1 (es)
MY (1) MY120976A (es)
NO (1) NO314803B1 (es)
NZ (2) NZ336623A (es)
OA (1) OA11084A (es)
PA (1) PA8446301A1 (es)
PE (1) PE58599A1 (es)
PL (1) PL335161A1 (es)
PT (1) PT958282E (es)
SI (1) SI0958282T1 (es)
SK (1) SK101199A3 (es)
TN (1) TNSN98024A1 (es)
TR (1) TR199901917T2 (es)
TW (1) TW458969B (es)
UA (1) UA64740C2 (es)
UY (1) UY24881A1 (es)
WO (1) WO1998034919A1 (es)
YU (1) YU35699A (es)
ZA (1) ZA981017B (es)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010049379A1 (en) 1997-08-27 2001-12-06 Lowe John Adams 2-aminopyridines containing fused ring substituents
AU765851B2 (en) * 1998-06-03 2003-10-02 Pfizer Products Inc. 2-aminopyridines containing fused ring substituents as nitric oxide synthase inhibitors
TR200401803T2 (tr) * 1998-08-11 2004-11-22 Pfizer Products Inc. NOS önleyicileri için yeni farmasötik kullanımlar.
SE9803710L (sv) 1998-09-25 2000-03-26 A & Science Invest Ab Användning av vissa substanser för behandling av nervrotsskador
US7115557B2 (en) 1998-09-25 2006-10-03 Sciaticon Ab Use of certain drugs for treating nerve root injury
HUP0200163A3 (en) * 1999-02-25 2002-11-28 Pfizer Prod Inc 2-aminopyridines containing fused ring substituents, pharmaceutical compositions containing them and their use
FR2812635B1 (fr) * 2000-08-01 2002-10-11 Aventis Pharma Sa Nouveaux composes heterocycliques, preparation et utilisation comme medicaments notamment comme anti- bacteriens
GB0019006D0 (en) * 2000-08-04 2000-09-20 Astrazeneca Ab Novel compounds
US20030045449A1 (en) * 2001-08-15 2003-03-06 Pfizer, Inc. Pharmaceutical combinations for the treatment of neurodegenerative diseases
US20030232739A1 (en) * 2001-08-15 2003-12-18 Pfizer Inc. Pharmaceutical combinations comprising a NOS inhibitor and an NMDA receptor antagonist
DOP2002000467A (es) * 2001-10-10 2003-04-15 Pfizer Prod Inc 2-amino-6 (fenilo sustituido en las posiciones 2,4,5)-piridinas
US6803470B2 (en) 2001-10-10 2004-10-12 Pfizer Inc 2-amino-6-(2,4,5-substituted-phenyl)-pyridines
US7045652B2 (en) 2002-07-03 2006-05-16 Pfizer Inc Processes for preparing substituted aryl boronic acids
US20040092741A1 (en) * 2002-11-08 2004-05-13 Pfizer Inc Substituted pyridines via boronic acid coupling
WO2005007627A1 (ja) * 2003-07-18 2005-01-27 Nihon Nohyaku Co., Ltd. フェニルピリジン誘導体、その中間体及びこれを有効成分とする除草剤
EP1850838A2 (en) * 2005-02-21 2007-11-07 Proximagen Ltd. Inhibition or treatment of dyskinesia
GB0607196D0 (en) * 2006-04-11 2006-05-17 Prosidion Ltd G-protein coupled receptor agonists
WO2008080938A1 (en) * 2006-12-28 2008-07-10 Basf Se Use 2-substituted pyridines for cancer treatment
UA105182C2 (ru) 2008-07-03 2014-04-25 Ньюрексон, Інк. Бензоксазины, бензотиазины и родственные соединения, которые имеют ингибирующую nos активность
JP6387023B2 (ja) 2013-02-28 2018-09-05 ティウムバイオ カンパニー、リミテッドTiumBio Co., Ltd. 三環式化合物およびその使用
AU2014346483B2 (en) * 2013-11-07 2019-01-17 The University Of Kansas Biphenylamide derivative Hsp90 inhibitors
US10562858B2 (en) * 2014-08-13 2020-02-18 Meiji Seika Pharma Co., Ltd. Crystalline anti-trichophyton agents and preparation process thereof
CN106265640B (zh) * 2016-08-11 2019-05-14 吉林大学 Appa在制备治疗糖尿病肾病药物中的应用
CN108069831B (zh) * 2018-01-25 2020-11-24 上海恩氟佳科技有限公司 一种合成2,3-二甲基-4-氟苯酚的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0674627A1 (en) * 1992-12-18 1995-10-04 The Wellcome Foundation Limited Pyrimidine, pyridine, pteridinone and indazole derivatives as enzyme inhibitors
EP0724570B1 (en) * 1993-10-21 1999-03-03 G.D. Searle & Co. Amidino derivatives useful as nitric oxide synthase inhibitors
WO1996018616A1 (en) * 1994-12-12 1996-06-20 Merck & Co., Inc. Substituted 2-aminopyridines as inhibitors of nitric oxide synthase
EP1471055A1 (en) * 1996-03-29 2004-10-27 Pfizer Inc. 6-phenylpyridyl-2-amine derivatives

Also Published As

Publication number Publication date
IS5118A (is) 1999-07-29
AU744313B2 (en) 2002-02-21
CN1246848A (zh) 2000-03-08
KR20000070803A (ko) 2000-11-25
PL335161A1 (en) 2000-04-10
US20010007873A1 (en) 2001-07-12
CO4920225A1 (es) 2000-05-29
DE69825147D1 (de) 2004-08-26
CN1515554A (zh) 2004-07-28
OA11084A (en) 2002-03-15
HUP0000762A2 (hu) 2000-09-28
BR9811093A (pt) 2000-07-18
DE69825147T2 (de) 2005-08-04
MY120976A (en) 2005-12-30
KR100460399B1 (ko) 2004-12-08
EP0958282A1 (en) 1999-11-24
DZ2414A1 (fr) 2003-01-04
ES2224354T3 (es) 2005-03-01
AU5572798A (en) 1998-08-26
NZ336623A (en) 2000-11-24
SK101199A3 (en) 2000-10-09
CN1523015A (zh) 2004-08-25
WO1998034919A1 (en) 1998-08-13
CZ276999A3 (cs) 2000-05-17
MA27676A1 (fr) 2006-01-02
AP833A (en) 2000-05-10
CA2277990A1 (en) 1998-08-13
PE58599A1 (es) 1999-06-12
DK0958282T3 (da) 2004-11-29
UY24881A1 (es) 2000-12-29
HUP0000762A3 (en) 2000-10-30
BG103633A (bg) 2000-11-30
TNSN98024A1 (fr) 2005-03-15
NO993823L (no) 1999-08-09
HN1998000030A (es) 1998-10-22
NO993823D0 (no) 1999-08-09
CA2277990C (en) 2006-08-01
IL130898A0 (en) 2001-01-28
AR011117A1 (es) 2000-08-02
NZ518345A (en) 2005-02-25
NO314803B1 (no) 2003-05-26
EA199900632A1 (ru) 2000-02-28
ATE271544T1 (de) 2004-08-15
PA8446301A1 (es) 2000-05-24
CZ292135B6 (cs) 2003-08-13
HRP980069A2 (en) 1998-12-31
UA64740C2 (uk) 2004-03-15
JP2000509408A (ja) 2000-07-25
TW458969B (en) 2001-10-11
TR199901917T2 (xx) 1999-12-21
EP0958282B1 (en) 2004-07-21
GT199800032A (es) 1998-02-11
JP3505189B2 (ja) 2004-03-08
US20030162765A1 (en) 2003-08-28
PT958282E (pt) 2004-11-30
SI0958282T1 (en) 2005-02-28
EA003834B1 (ru) 2003-10-30
YU35699A (sh) 2002-06-19

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