OA10803A - Process for preparing 2,4-dihydroxypyridine and 2,4-dihydroxy-3-nitropyridine - Google Patents

Process for preparing 2,4-dihydroxypyridine and 2,4-dihydroxy-3-nitropyridine Download PDF

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Publication number
OA10803A
OA10803A OA9800099A OA9800099A OA10803A OA 10803 A OA10803 A OA 10803A OA 9800099 A OA9800099 A OA 9800099A OA 9800099 A OA9800099 A OA 9800099A OA 10803 A OA10803 A OA 10803A
Authority
OA
OAPI
Prior art keywords
adenosine
acid
thienyl
ethyl
compounds
Prior art date
Application number
OA9800099A
Other languages
English (en)
Inventor
Larry K Truesdale
James P Sherbine
Benoit J Vanasse
Original Assignee
Rhone Poulenc Rorer Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Pharma filed Critical Rhone Poulenc Rorer Pharma
Publication of OA10803A publication Critical patent/OA10803A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/64—One oxygen atom attached in position 2 or 6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
OA9800099A 1996-01-02 1998-07-01 Process for preparing 2,4-dihydroxypyridine and 2,4-dihydroxy-3-nitropyridine OA10803A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US949296P 1996-01-02 1996-01-02

Publications (1)

Publication Number Publication Date
OA10803A true OA10803A (en) 2003-01-28

Family

ID=21737998

Family Applications (1)

Application Number Title Priority Date Filing Date
OA9800099A OA10803A (en) 1996-01-02 1998-07-01 Process for preparing 2,4-dihydroxypyridine and 2,4-dihydroxy-3-nitropyridine

Country Status (21)

Country Link
US (2) US6307054B1 (cs)
EP (1) EP0909270B1 (cs)
JP (1) JP2000502709A (cs)
KR (1) KR19990076966A (cs)
AP (1) AP772A (cs)
AT (1) ATE219767T1 (cs)
AU (1) AU722894B2 (cs)
BR (1) BR9612341A (cs)
CA (1) CA2241887C (cs)
CZ (1) CZ203998A3 (cs)
DE (1) DE69622051T2 (cs)
DK (1) DK0909270T3 (cs)
EA (1) EA000884B1 (cs)
ES (1) ES2178725T3 (cs)
HU (1) HUP9900969A3 (cs)
IL (1) IL125164A (cs)
OA (1) OA10803A (cs)
PT (1) PT909270E (cs)
SI (1) SI9620137B (cs)
SK (1) SK283625B6 (cs)
WO (1) WO1997024327A1 (cs)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9917000A (pt) 1998-12-31 2001-12-11 Aventis Pharm Prod Inc Processo para preparar derivados dedesaza-adenosina n6-substituìda
US7018365B2 (en) 1999-05-21 2006-03-28 Micro Therapeutics, Inc. Threaded syringe with quick stop
US6784165B1 (en) * 1999-11-23 2004-08-31 Aderis Pharmaceuticals, Inc. Treatment of heart rhythm disturbances with N6-substituted-5′-(N-substituted) carboxamidoadenosines
US7291603B2 (en) 2002-07-24 2007-11-06 Ptc Therapeutics, Inc. Nucleoside compounds and their use for treating cancer and diseases associated with somatic mutations
US20050009776A1 (en) * 2003-04-24 2005-01-13 Aderis Pharmaceuticals, Inc. Method of treating atrial fibrillation or atrial flutter
WO2005025545A2 (en) * 2003-09-17 2005-03-24 Aderis Pharmaceuticals, Inc. Pharmaceutical formulation for controlled release of selodenoson
GT200500281A (es) * 2004-10-22 2006-04-24 Novartis Ag Compuestos organicos.
GB0500785D0 (en) * 2005-01-14 2005-02-23 Novartis Ag Organic compounds
GB0607944D0 (en) * 2006-04-21 2006-05-31 Novartis Ag Organic compounds
PT2013211E (pt) * 2006-04-21 2012-06-21 Novartis Ag Derivados de purina para utilização como agonistas de receptores a2a de adenosina
GB0607948D0 (en) * 2006-04-21 2006-05-31 Novartis Ag Organic compounds
GB0607950D0 (en) * 2006-04-21 2006-05-31 Novartis Ag Organic compounds
GB0607953D0 (en) * 2006-04-21 2006-05-31 Novartis Ag Organic compounds
EP1889846A1 (en) 2006-07-13 2008-02-20 Novartis AG Purine derivatives as A2a agonists
EP1903044A1 (en) * 2006-09-14 2008-03-26 Novartis AG Adenosine Derivatives as A2A Receptor Agonists
KR20090087054A (ko) * 2006-11-10 2009-08-14 노파르티스 아게 시클로펜텐 디올 모노아세테이트 유도체
JP2012516843A (ja) 2009-02-02 2012-07-26 インドコ レメディーズ リミテッド ニトロピリジン誘導体の調製方法
CN114349873B (zh) * 2021-04-12 2023-03-17 杭州安誉科技有限公司 用于多孔模块辅助控制装置的高强度风扇支架
CN115716802A (zh) * 2022-10-20 2023-02-28 山西永津集团有限公司 一种4-溴-2-氯烟腈的合成方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3547935A (en) * 1967-08-07 1970-12-15 American Cyanamid Co Certain nitro-4-pyridinols,n-oxides thereof and derivatives thereof
GB1199699A (en) * 1968-01-08 1970-07-22 Glanzstoff Ag Process for the Production of Condensed Aromatic Bis-(2,4-Dihydroxypyridine) Derivatives
DE3308449A1 (de) * 1982-08-19 1984-03-15 Rütgerswerke AG, 6000 Frankfurt Verfahren zur reindarstellung von 2-chlor-6-alkoxy-3-nitropyridinen
JP3261190B2 (ja) * 1993-01-27 2002-02-25 広栄化学工業株式会社 ２−ヒドロキシ−３，５−ジニトロピリジン類の製造法

Also Published As

Publication number Publication date
CA2241887C (en) 2004-02-24
JP2000502709A (ja) 2000-03-07
ATE219767T1 (de) 2002-07-15
AU722894B2 (en) 2000-08-10
SI9620137A (sl) 1999-02-28
BR9612341A (pt) 1999-12-28
IL125164A (en) 2003-03-12
AP772A (en) 1999-10-15
IL125164A0 (en) 1999-01-26
US6307054B1 (en) 2001-10-23
ES2178725T3 (es) 2003-01-01
DE69622051T2 (de) 2003-01-23
AU1354697A (en) 1997-07-28
DE69622051D1 (de) 2002-08-01
SI9620137B (sl) 2006-02-28
HUP9900969A2 (hu) 1999-07-28
CZ203998A3 (cs) 1999-11-17
WO1997024327A1 (en) 1997-07-10
SK283625B6 (sk) 2003-10-07
EP0909270A1 (en) 1999-04-21
HUP9900969A3 (en) 2001-11-28
PT909270E (pt) 2002-11-29
HK1019590A1 (en) 2000-02-18
AP9801289A0 (en) 1998-09-30
DK0909270T3 (da) 2002-10-07
EP0909270B1 (en) 2002-06-26
KR19990076966A (ko) 1999-10-25
SK90698A3 (en) 2000-12-11
EA000884B1 (ru) 2000-06-26
EP0909270A4 (cs) 1999-04-21
US6392049B1 (en) 2002-05-21
EA199800621A1 (ru) 1999-02-25
CA2241887A1 (en) 1997-07-10

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