OA10079A - Anti-cd4 antibody homologs useful in prophylaxis and treatment of aids arc and hiv infection - Google Patents

Anti-cd4 antibody homologs useful in prophylaxis and treatment of aids arc and hiv infection Download PDF

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Publication number
OA10079A
OA10079A OA60249A OA60249A OA10079A OA 10079 A OA10079 A OA 10079A OA 60249 A OA60249 A OA 60249A OA 60249 A OA60249 A OA 60249A OA 10079 A OA10079 A OA 10079A
Authority
OA
OAPI
Prior art keywords
antibody
seq
ser
human
leu
Prior art date
Application number
OA60249A
Other languages
English (en)
Inventor
Linda C Burkly
Patricia L Chisholm
Davis W Thomas
Margaret D Rosa
Joseph J Rosa
Original Assignee
Biogen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogen Inc filed Critical Biogen Inc
Publication of OA10079A publication Critical patent/OA10079A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2812—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
OA60249A 1990-11-27 1992-07-27 Anti-cd4 antibody homologs useful in prophylaxis and treatment of aids arc and hiv infection OA10079A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US61854290A 1990-11-27 1990-11-27
PCT/US1991/008843 WO1992009305A1 (en) 1990-11-27 1991-11-27 Anti cd-4 antibodies blocking hiv-induced syncytia

Publications (1)

Publication Number Publication Date
OA10079A true OA10079A (en) 1996-12-18

Family

ID=24478147

Family Applications (1)

Application Number Title Priority Date Filing Date
OA60249A OA10079A (en) 1990-11-27 1992-07-27 Anti-cd4 antibody homologs useful in prophylaxis and treatment of aids arc and hiv infection

Country Status (12)

Country Link
US (1) US5871732A (enExample)
EP (1) EP0512112B1 (enExample)
JP (5) JPH05505112A (enExample)
AT (1) ATE153536T1 (enExample)
AU (1) AU662891B2 (enExample)
CA (1) CA2073031C (enExample)
DE (1) DE69126301T2 (enExample)
DK (1) DK0512112T3 (enExample)
ES (1) ES2101834T3 (enExample)
GR (1) GR3024274T3 (enExample)
OA (1) OA10079A (enExample)
WO (1) WO1992009305A1 (enExample)

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US6420545B1 (en) * 1999-05-24 2002-07-16 The Trustees Of The University Of Pennsylvania CD4-independent HIV envelope proteins as vaccines and therapeutics
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AU2007286451A1 (en) * 2006-08-17 2008-02-21 F. Hoffmann-La Roche Ag A conjugate of an antibody against CCR5 and an antifusogenic peptide
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US10894087B2 (en) 2010-12-22 2021-01-19 Nektar Therapeutics Multi-arm polymeric prodrug conjugates of cabazitaxel-based compounds
US20130331443A1 (en) 2010-12-22 2013-12-12 Nektar Therapeutics Multi-arm polymeric prodrug conjugates of taxane-based compounds
WO2012166555A1 (en) 2011-05-27 2012-12-06 Nektar Therapeutics Water - soluble polymer - linked binding moiety and drug compounds
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CN102321653B (zh) * 2011-07-18 2013-11-20 清华大学 人鼠嵌合型cd4质粒及其多抗在抑制hiv感染中的应用
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US11180555B2 (en) 2014-09-16 2021-11-23 Ubi Us Holdings, Llc. Antibodies directed against CD4 for the treatment and functional cure of HIV
US10174292B2 (en) 2015-03-20 2019-01-08 International Aids Vaccine Initiative Soluble HIV-1 envelope glycoprotein trimers
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Also Published As

Publication number Publication date
EP0512112B1 (en) 1997-05-28
HK1007686A1 (en) 1999-04-23
JP2002356499A (ja) 2002-12-13
WO1992009305A1 (en) 1992-06-11
JPH05505112A (ja) 1993-08-05
DE69126301T2 (de) 1998-01-02
JP2005041859A (ja) 2005-02-17
CA2073031A1 (en) 1992-05-28
EP0512112A1 (en) 1992-11-11
ES2101834T3 (es) 1997-07-16
US5871732A (en) 1999-02-16
CA2073031C (en) 2002-10-01
GR3024274T3 (en) 1997-10-31
JP2007151556A (ja) 2007-06-21
AU662891B2 (en) 1995-09-21
DE69126301D1 (de) 1997-07-03
ATE153536T1 (de) 1997-06-15
JP2007175055A (ja) 2007-07-12
AU9154391A (en) 1992-06-25
DK0512112T3 (da) 1997-09-29
JP4642035B2 (ja) 2011-03-02

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