OA07412A - Benzoazacycloalhyl-spiro-imidazolidines their preparation and their application in therapy. - Google Patents
Benzoazacycloalhyl-spiro-imidazolidines their preparation and their application in therapy.Info
- Publication number
- OA07412A OA07412A OA57984A OA57984A OA07412A OA 07412 A OA07412 A OA 07412A OA 57984 A OA57984 A OA 57984A OA 57984 A OA57984 A OA 57984A OA 07412 A OA07412 A OA 07412A
- Authority
- OA
- OAPI
- Prior art keywords
- benzoazacycloalhyl
- imidazolidines
- spiro
- therapy
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/38—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to acyclic carbon atoms and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/24—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/16—Benzazepines; Hydrogenated benzazepines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/10—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Ophthalmology & Optometry (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8207203A FR2525603A1 (en) | 1982-04-27 | 1982-04-27 | BENZOAZACYCLOALKYL-SPIRO-IMIDAZOLININES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| OA07412A true OA07412A (en) | 1984-11-30 |
Family
ID=9273425
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| OA57984A OA07412A (en) | 1982-04-27 | 1983-04-27 | Benzoazacycloalhyl-spiro-imidazolidines their preparation and their application in therapy. |
Country Status (22)
| Country | Link |
|---|---|
| JP (1) | JPS5910584A (en) |
| KR (1) | KR840004428A (en) |
| AT (1) | ATA125383A (en) |
| AU (1) | AU1395383A (en) |
| BE (1) | BE896572A (en) |
| DD (1) | DD209833A5 (en) |
| DE (1) | DE3315106A1 (en) |
| DK (1) | DK183583A (en) |
| ES (1) | ES521895A0 (en) |
| FR (1) | FR2525603A1 (en) |
| GB (1) | GB2133401B (en) |
| GR (1) | GR78481B (en) |
| IL (1) | IL68497A0 (en) |
| IT (1) | IT1167123B (en) |
| LU (1) | LU84770A1 (en) |
| MA (1) | MA19783A1 (en) |
| NL (1) | NL8301476A (en) |
| NO (1) | NO831473L (en) |
| OA (1) | OA07412A (en) |
| PT (1) | PT76595B (en) |
| SE (1) | SE8302347L (en) |
| ZA (1) | ZA832927B (en) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU617541B2 (en) * | 1988-10-20 | 1991-11-28 | Wyeth | Spiro-isoquinoline-pyrrolidine tetrones and analogs thereof useful as aldose reductase inhibitors |
| US4927831A (en) * | 1988-10-20 | 1990-05-22 | American Home Products | Spiro-isoquinoline-pyrrolidine tetrones and analogs thereof useful as aldose reductase inhibitors |
| US6953787B2 (en) | 2002-04-12 | 2005-10-11 | Arena Pharmaceuticals, Inc. | 5HT2C receptor modulators |
| CN1805939B (en) | 2003-06-17 | 2010-10-13 | 艾尼纳制药公司 | Benzazepine derivatives useful for the treatment of 5HT2C receptor associated diseases |
| SI2332921T1 (en) | 2003-06-17 | 2016-06-30 | Arena Pharmaceuticals, Inc. | 8-Chloro-1 -methyl-2,3,4,5-tetrahydro-1 H-3benzazapine Hydrochloride |
| EP1838677B1 (en) | 2004-12-21 | 2009-09-09 | Arena Pharmaceuticals, Inc. | Crystalline forms of (r)-8-chloro-1-methyl- 2,3,4,5-tetrahydro-1h-3-benzazepine hydrochloride |
| EP2322162A1 (en) | 2004-12-23 | 2011-05-18 | Arena Pharmaceuticals, Inc. | 5HT2C receptor modulator compositions and methods of use |
| JP5199997B2 (en) | 2006-04-03 | 2013-05-15 | アリーナ ファーマシューティカルズ， インコーポレイテッド | Process for preparing 8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine and related intermediates |
| EP2099743B1 (en) | 2006-12-05 | 2014-08-27 | Arena Pharmaceuticals, Inc. | Processes for preparing (r)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine and intermediates thereof |
| US8822727B2 (en) | 2008-03-04 | 2014-09-02 | Arena Pharmaceuticals, Inc. | Processes for the preparation of intermediates related to the 5-HT2C agonist (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine |
| US8952197B2 (en) | 2009-06-18 | 2015-02-10 | Arena Pharmaceuticals, Inc. | Processes for the preparation of 5-HT2C receptor agonists |
| KR20130112848A (en) | 2010-06-02 | 2013-10-14 | 아레나 파마슈티칼스, 인크. | Processes for the preparation of 5-ht2c receptor agonists |
| CA2808904A1 (en) | 2010-09-01 | 2012-03-08 | Arena Pharmaceuticals, Inc. | Non-hygroscopic salts of 5-ht2c agonists |
| EP2611449A1 (en) | 2010-09-01 | 2013-07-10 | Arena Pharmaceuticals, Inc. | Administration of lorcaserin to individuals with renal impairment |
| EP3485878A1 (en) | 2010-09-01 | 2019-05-22 | Arena Pharmaceuticals, Inc. | Modified-release dosage forms of 5-ht2c agonists useful for weight management |
| SG188364A1 (en) | 2010-09-01 | 2013-04-30 | Arena Pharm Inc | Salts of lorcaserin with optically active acids |
| RU2674670C1 (en) | 2012-10-09 | 2018-12-12 | Арена Фармасьютикалз, Инк. | Method of correction of body mass |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4209630A (en) * | 1976-10-18 | 1980-06-24 | Pfizer Inc. | Hydantoin derivatives as therapeutic agents |
| US4235911A (en) * | 1979-06-13 | 1980-11-25 | Pfizer Inc. | Hydantoin derivatives |
-
1982
- 1982-04-27 FR FR8207203A patent/FR2525603A1/en active Granted
-
1983
- 1983-04-08 AT AT0125383A patent/ATA125383A/en not_active IP Right Cessation
- 1983-04-25 LU LU84770A patent/LU84770A1/en unknown
- 1983-04-25 DD DD83250187A patent/DD209833A5/en unknown
- 1983-04-26 JP JP58073687A patent/JPS5910584A/en active Pending
- 1983-04-26 GR GR71214A patent/GR78481B/el unknown
- 1983-04-26 NL NL8301476A patent/NL8301476A/en not_active Application Discontinuation
- 1983-04-26 IT IT48155/83A patent/IT1167123B/en active
- 1983-04-26 ZA ZA832927A patent/ZA832927B/en unknown
- 1983-04-26 BE BE0/210633A patent/BE896572A/en not_active IP Right Cessation
- 1983-04-26 NO NO831473A patent/NO831473L/en unknown
- 1983-04-26 DK DK183583A patent/DK183583A/en not_active Application Discontinuation
- 1983-04-26 AU AU13953/83A patent/AU1395383A/en not_active Abandoned
- 1983-04-26 SE SE8302347A patent/SE8302347L/en not_active Application Discontinuation
- 1983-04-26 KR KR1019830001753A patent/KR840004428A/en not_active Application Discontinuation
- 1983-04-26 IL IL68497A patent/IL68497A0/en unknown
- 1983-04-26 PT PT76595A patent/PT76595B/en unknown
- 1983-04-27 GB GB08311508A patent/GB2133401B/en not_active Expired
- 1983-04-27 OA OA57984A patent/OA07412A/en unknown
- 1983-04-27 DE DE19833315106 patent/DE3315106A1/en not_active Withdrawn
- 1983-04-27 MA MA20003A patent/MA19783A1/en unknown
- 1983-04-27 ES ES521895A patent/ES521895A0/en active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| NL8301476A (en) | 1983-11-16 |
| PT76595B (en) | 1986-01-21 |
| IT8348155A0 (en) | 1983-04-26 |
| LU84770A1 (en) | 1984-11-28 |
| DD209833A5 (en) | 1984-05-23 |
| BE896572A (en) | 1983-10-26 |
| GB2133401A (en) | 1984-07-25 |
| ATA125383A (en) | 1986-05-15 |
| GB2133401B (en) | 1985-10-23 |
| SE8302347L (en) | 1983-10-28 |
| FR2525603A1 (en) | 1983-10-28 |
| MA19783A1 (en) | 1983-12-31 |
| IT1167123B (en) | 1987-05-13 |
| ES8405796A1 (en) | 1984-06-16 |
| JPS5910584A (en) | 1984-01-20 |
| IL68497A0 (en) | 1983-07-31 |
| GR78481B (en) | 1984-09-27 |
| DK183583A (en) | 1983-10-28 |
| DK183583D0 (en) | 1983-04-26 |
| ES521895A0 (en) | 1984-06-16 |
| AU1395383A (en) | 1983-11-03 |
| GB8311508D0 (en) | 1983-06-02 |
| ZA832927B (en) | 1984-06-27 |
| PT76595A (en) | 1983-05-01 |
| SE8302347D0 (en) | 1983-04-26 |
| KR840004428A (en) | 1984-10-15 |
| NO831473L (en) | 1983-10-28 |
| DE3315106A1 (en) | 1983-11-03 |
| FR2525603B1 (en) | 1984-09-14 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MA19845A1 (en) | NEW PIPERIDINAMINES AND THEIR PREPARATION | |
| LU81439A1 (en) | OCTAHYDRO-PYRAZOLO (3,4-G) QUINOLEINES AND THEIR THERAPEUTIC USE | |
| OA07412A (en) | Benzoazacycloalhyl-spiro-imidazolidines their preparation and their application in therapy. | |
| DE3378954D1 (en) | Perfluorocarbon emulsions and their preparation and use in therapy | |
| BE888396A (en) | DIAGNOSTIC AND THERAPEUTIC CAPSULES AND THEIR PREPARATION, | |
| FR2545825B1 (en) | 1-PYRIMIDINYLOXY-3-HETARYLALKYLAMINO-2-PROPANOLS, THEIR PREPARATION AND THEIR THERAPEUTIC USES | |
| OA07332A (en) | Oximes-ethers, their preparation and use. | |
| BE896018A (en) | PYRROLACETIC AMIDES, THEIR PREPARATION AND THEIR USE | |
| BE882166A (en) | 9-AMINOALKYLFLUORENES, THEIR PREPARATION AND THEIR THERAPEUTIC USE | |
| FR2568879B1 (en) | IMIDAZO (1,2-A) QUINOLINES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | |
| BE891585A (en) | 5 ALPHA-ANDROSTANE-17 BETA-CARBOXYLATES AND 5 BETA-ANDROSTANE-17 BETA-CARBOXYLATES, THEIR PREPARATION AND THEIR USE | |
| DE3583698D1 (en) | PERCUTANIC ABSORPTION ACCELERATOR AND PREPARATION CONTAINING THEM. | |
| BE885999A (en) | NEWS 1-OXADETHIACEPHALOSPORINS AND THEIR PREPARATION | |
| MA19965A1 (en) | 3 ', 5'-DIARABINOSIDES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | |
| LU81440A1 (en) | OCTAHYDRO-2H-PYRROLO (3,4-G) QUINOLEINES AND THEIR THERAPEUTIC USE | |
| BE874430A (en) | 2,3-DIHYDROIMIDAZO (1,2, C) SUBSTITUTED PYRIMIDINES AND THEIR THERAPEUTIC USE | |
| LU81437A1 (en) | 2-AZAERGOLINES AND 2-AZA-8 (OR 9) ERGOLENES AND THEIR THERAPEUTIC USE | |
| FR2516509B1 (en) | BENZYLIDENIC DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | |
| FR2544309B1 (en) | HYDROXYLATED DIPHENYLAZOMETHINES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | |
| FR2522936B1 (en) | WHIPPED TREATMENT AND ITS PREPARATION | |
| BE882167A (en) | (1,1-BIPHENYL-2-YL) -PROPYL- AND BUTYLAMINES, THEIR PREPARATION AND THEIR THERAPEUTIC USE | |
| LU81350A1 (en) | ARYLALKYL-ET ARYLOXYALKYL-PHOSPHONATES, THEIR PREPARATION AND THEIR THERAPEUTIC USE | |
| NO834302L (en) | INDEPENDENT TREATMENT AND TRACK ROLLING | |
| BE880288A (en) | HEXAHYDRO-2,6-METHANO-3-BENZAZOCINS, THEIR PREPARATION AND THEIR THERAPEUTIC USE | |
| DK565783A (en) | THERAPEUTIC PREPARATION CONTAINING HYDROGENERED ERGOTAL CHALOIDS AND HEPARIN |