DK183583D0 - METHOD FOR PREPARING BENZOAZACYCLOALKYL-SPIRO-IMIDAZOLIDINES - Google Patents

METHOD FOR PREPARING BENZOAZACYCLOALKYL-SPIRO-IMIDAZOLIDINES

Info

Publication number
DK183583D0
DK183583D0 DK1835/83A DK183583A DK183583D0 DK 183583 D0 DK183583 D0 DK 183583D0 DK 1835/83 A DK1835/83 A DK 1835/83A DK 183583 A DK183583 A DK 183583A DK 183583 D0 DK183583 D0 DK 183583D0
Authority
DK
Denmark
Prior art keywords
benzoazacycloalkyl
imidazolidines
spiro
preparing
preparing benzoazacycloalkyl
Prior art date
Application number
DK1835/83A
Other languages
Danish (da)
Other versions
DK183583A (en
Inventor
Charles Malen
Jean-Louis Peglion
Jacques Duhault
Michelle Boulanger
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Publication of DK183583D0 publication Critical patent/DK183583D0/en
Publication of DK183583A publication Critical patent/DK183583A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10Spiro-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/12Ophthalmic agents for cataracts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/38Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to acyclic carbon atoms and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/24Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/26Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16Benzazepines; Hydrogenated benzazepines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/10Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DK183583A 1982-04-27 1983-04-26 PROCEDURE FOR PREPARING BENZOAZACYCLOALKYL-SPIRO-IMIDAZOLIDINES DK183583A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8207203A FR2525603A1 (en) 1982-04-27 1982-04-27 BENZOAZACYCLOALKYL-SPIRO-IMIDAZOLININES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
FR8207203 1982-04-27

Publications (2)

Publication Number Publication Date
DK183583D0 true DK183583D0 (en) 1983-04-26
DK183583A DK183583A (en) 1983-10-28

Family

ID=9273425

Family Applications (1)

Application Number Title Priority Date Filing Date
DK183583A DK183583A (en) 1982-04-27 1983-04-26 PROCEDURE FOR PREPARING BENZOAZACYCLOALKYL-SPIRO-IMIDAZOLIDINES

Country Status (22)

Country Link
JP (1) JPS5910584A (en)
KR (1) KR840004428A (en)
AT (1) ATA125383A (en)
AU (1) AU1395383A (en)
BE (1) BE896572A (en)
DD (1) DD209833A5 (en)
DE (1) DE3315106A1 (en)
DK (1) DK183583A (en)
ES (1) ES8405796A1 (en)
FR (1) FR2525603A1 (en)
GB (1) GB2133401B (en)
GR (1) GR78481B (en)
IL (1) IL68497A0 (en)
IT (1) IT1167123B (en)
LU (1) LU84770A1 (en)
MA (1) MA19783A1 (en)
NL (1) NL8301476A (en)
NO (1) NO831473L (en)
OA (1) OA07412A (en)
PT (1) PT76595B (en)
SE (1) SE8302347L (en)
ZA (1) ZA832927B (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU617541B2 (en) * 1988-10-20 1991-11-28 Wyeth Spiro-isoquinoline-pyrrolidine tetrones and analogs thereof useful as aldose reductase inhibitors
US4927831A (en) * 1988-10-20 1990-05-22 American Home Products Spiro-isoquinoline-pyrrolidine tetrones and analogs thereof useful as aldose reductase inhibitors
US6953787B2 (en) 2002-04-12 2005-10-11 Arena Pharmaceuticals, Inc. 5HT2C receptor modulators
PL2332921T3 (en) 2003-06-17 2016-08-31 Arena Pharm Inc 8-Chloro-1 -methyl-2,3,4,5-tetrahydro-1 H-3benzazapine Hydrochloride
EP2332920A3 (en) 2003-06-17 2011-12-21 Arena Pharmaceuticals, Inc. Processes for preparing 3-benzazepines
NZ555981A (en) 2004-12-21 2011-01-28 Arena Pharm Inc Crystalline forms of (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride
NZ555482A (en) 2004-12-23 2011-01-28 Arena Pharm Inc Compositions comprising a 5HT2C receptor modulator and 2-methylamphetamine and methods of use
EP2471779A1 (en) 2006-04-03 2012-07-04 Arena Pharmaceuticals, Inc. Process for the resolution of a mixture of (R)- and (S)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine
ES2522587T3 (en) 2006-12-05 2014-11-17 Arena Pharmaceuticals, Inc. Processes for preparing (R) -8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzacepin and intermediates thereof
WO2009111004A1 (en) 2008-03-04 2009-09-11 Arena Pharmaceuticals, Inc. Processes for the preparation of intermediates related to the 5-ht2c agonist (r)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine
US8952197B2 (en) 2009-06-18 2015-02-10 Arena Pharmaceuticals, Inc. Processes for the preparation of 5-HT2C receptor agonists
KR20130112848A (en) 2010-06-02 2013-10-14 아레나 파마슈티칼스, 인크. Processes for the preparation of 5-ht2c receptor agonists
CN103347523A (en) 2010-09-01 2013-10-09 艾尼纳制药公司 Administration of lorcaserin to individual with renal impairment
WO2012030957A2 (en) 2010-09-01 2012-03-08 Arena Pharmaceuticals, Inc. Non-hygroscopic salts of 5-ht2c agonists
KR20180118801A (en) 2010-09-01 2018-10-31 에자이 알앤드디 매니지먼트 가부시키가이샤 Modified-release dosage forms of 5-ht2c agonists useful for weight management
CA2808909A1 (en) 2010-09-01 2012-03-08 Arena Pharmaceuticals, Inc. Salts of lorcaserin with optically active acids
BR112015007779A2 (en) 2012-10-09 2017-07-04 Arena Pharm Inc permeability flow cell and hydraulic conductance system

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4209630A (en) * 1976-10-18 1980-06-24 Pfizer Inc. Hydantoin derivatives as therapeutic agents
US4235911A (en) * 1979-06-13 1980-11-25 Pfizer Inc. Hydantoin derivatives

Also Published As

Publication number Publication date
ATA125383A (en) 1986-05-15
SE8302347L (en) 1983-10-28
DE3315106A1 (en) 1983-11-03
KR840004428A (en) 1984-10-15
LU84770A1 (en) 1984-11-28
SE8302347D0 (en) 1983-04-26
DK183583A (en) 1983-10-28
ES521895A0 (en) 1984-06-16
AU1395383A (en) 1983-11-03
BE896572A (en) 1983-10-26
IT1167123B (en) 1987-05-13
FR2525603B1 (en) 1984-09-14
DD209833A5 (en) 1984-05-23
NO831473L (en) 1983-10-28
GR78481B (en) 1984-09-27
NL8301476A (en) 1983-11-16
PT76595B (en) 1986-01-21
FR2525603A1 (en) 1983-10-28
PT76595A (en) 1983-05-01
IL68497A0 (en) 1983-07-31
ES8405796A1 (en) 1984-06-16
MA19783A1 (en) 1983-12-31
JPS5910584A (en) 1984-01-20
IT8348155A0 (en) 1983-04-26
GB8311508D0 (en) 1983-06-02
GB2133401A (en) 1984-07-25
OA07412A (en) 1984-11-30
ZA832927B (en) 1984-06-27
GB2133401B (en) 1985-10-23

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Legal Events

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AHB Application shelved due to non-payment