NZ715686A - Pharmaceutical for oral delivery comprising mgbg and methods of treating disease - Google Patents
Pharmaceutical for oral delivery comprising mgbg and methods of treating diseaseInfo
- Publication number
- NZ715686A NZ715686A NZ715686A NZ71568610A NZ715686A NZ 715686 A NZ715686 A NZ 715686A NZ 715686 A NZ715686 A NZ 715686A NZ 71568610 A NZ71568610 A NZ 71568610A NZ 715686 A NZ715686 A NZ 715686A
- Authority
- NZ
- New Zealand
- Prior art keywords
- mgbg
- pharmaceutical
- methods
- oral delivery
- treating disease
- Prior art date
Links
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- MXWHMTNPTTVWDM-NXOFHUPFSA-N mitoguazone Chemical compound NC(N)=N\N=C(/C)\C=N\N=C(N)N MXWHMTNPTTVWDM-NXOFHUPFSA-N 0.000 abstract 4
- 229960003539 mitoguazone Drugs 0.000 abstract 3
- 206010065390 Inflammatory pain Diseases 0.000 abstract 1
- 208000002193 Pain Diseases 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 238000001990 intravenous administration Methods 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
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- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
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- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
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- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
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- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
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- A61K9/4866—Organic macromolecular compounds
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- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Physical Education & Sports Medicine (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Diabetes (AREA)
- Pain & Pain Management (AREA)
- Biophysics (AREA)
- Heart & Thoracic Surgery (AREA)
- Obesity (AREA)
- Psychiatry (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Cardiology (AREA)
- Biotechnology (AREA)
- Endocrinology (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22606009P | 2009-07-16 | 2009-07-16 | |
| US29009509P | 2009-12-24 | 2009-12-24 | |
| NZ628513A NZ628513A (en) | 2009-07-16 | 2010-07-16 | Pharmaceutical for oral delivery comprising mgbg and methods of treating disease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ715686A true NZ715686A (en) | 2017-08-25 |
Family
ID=43450234
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ715686A NZ715686A (en) | 2009-07-16 | 2010-07-16 | Pharmaceutical for oral delivery comprising mgbg and methods of treating disease |
| NZ597488A NZ597488A (en) | 2009-07-16 | 2010-07-16 | Pharmaceutical for oral delivery comprising mgbg and methods of treating disease |
| NZ628513A NZ628513A (en) | 2009-07-16 | 2010-07-16 | Pharmaceutical for oral delivery comprising mgbg and methods of treating disease |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ597488A NZ597488A (en) | 2009-07-16 | 2010-07-16 | Pharmaceutical for oral delivery comprising mgbg and methods of treating disease |
| NZ628513A NZ628513A (en) | 2009-07-16 | 2010-07-16 | Pharmaceutical for oral delivery comprising mgbg and methods of treating disease |
Country Status (11)
| Country | Link |
|---|---|
| US (4) | US8258186B2 (enExample) |
| EP (2) | EP2453886B1 (enExample) |
| JP (4) | JP6112449B2 (enExample) |
| CN (2) | CN104997762B (enExample) |
| AU (2) | AU2010273277B2 (enExample) |
| BR (1) | BR112012000862A8 (enExample) |
| CA (1) | CA2768018C (enExample) |
| DK (1) | DK2453886T3 (enExample) |
| ES (1) | ES2715173T3 (enExample) |
| NZ (3) | NZ715686A (enExample) |
| WO (1) | WO2011009039A2 (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2627676T3 (es) | 2007-03-09 | 2017-07-31 | Pathologica Llc | MGBG para la regulación de osteopontina y el tratamiento de la esclerosis múltiple |
| DK2453886T3 (en) | 2009-07-16 | 2019-03-25 | Pathologica Llc | ORGANIC ADMINISTRATION COMPREHENSIVE MGBG AND DISEASE METHODS |
| US9675566B2 (en) * | 2009-07-16 | 2017-06-13 | Pathologica Llc | Method of treatment with anti-inflammatory and analgesic compounds which are GI-, renal-, and platelet-sparing |
| ES2662373T3 (es) | 2011-01-19 | 2018-04-06 | Pathologica, Llc. | Formas de dosificación farmacéutica oral de liberación controlada que comprenden MGBG |
| WO2013083813A2 (en) * | 2011-12-07 | 2013-06-13 | Universität Zürich | Modulators of spermine/spermidine n'-acetyltransferase (ssat) and ssat associated proteins for use in prevention or treatment of rheumatoid arthritis |
| US20140107218A1 (en) * | 2012-10-15 | 2014-04-17 | Nestec Sa | Methods for maintaining eye health and ameliorating opthalmic maladies in animals |
| CN109432073A (zh) | 2013-01-08 | 2019-03-08 | 帕萨罗杰卡有限公司 | Mgbg在制备治疗或预防进行性ms及其进展的药物中的用途 |
| CA3015849A1 (en) | 2016-03-25 | 2017-09-28 | Mark R. Burns | Bioavailable polyamines |
| WO2018027149A1 (en) * | 2016-08-04 | 2018-02-08 | University Of Miami | Methods of treating alport syndrome |
| JP6840386B2 (ja) * | 2017-04-26 | 2021-03-10 | 学校法人 関西大学 | 細胞足場材料製造用組成物ならびに細胞足場材料およびその製造方法 |
| WO2021202885A1 (en) * | 2020-04-03 | 2021-10-07 | Baylor College Of Medicine | TNFα SIGNALING TRIGGERS TUMOR-PROMOTING INFLAMMATION THAT CAN BE TARGETED TO THERAPY |
| JP2023545674A (ja) | 2020-09-30 | 2023-10-31 | アミネックス セラピューティクス, インコーポレイテッド | ポリアミン輸送阻害剤およびdfmoの配合原薬 |
| WO2024155777A2 (en) * | 2023-01-19 | 2024-07-25 | Dare Bioscience, Inc. | Compositions and techniques for treatment of polycystic ovarian syndrome (pcos) and endometriosis |
| WO2024155775A2 (en) * | 2023-01-19 | 2024-07-25 | Dare Bioscience, Inc. | Compositions and techniques for treatment of polycystic ovarian syndrome (pcos) and endometriosis |
| AU2024211707A1 (en) * | 2023-01-25 | 2025-08-07 | Dare Bioscience, Inc. | Compositions and methods for treating dysmenorrhea |
Family Cites Families (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4201788A (en) * | 1976-10-20 | 1980-05-06 | University Patents, Inc. | Process for alleviating proliferative skin diseases |
| US5614557A (en) * | 1977-07-11 | 1997-03-25 | Marion Merrell Et Compagnie C/O Merrell Pharmaceuticals Inc. | Method of controlling tumor growth rate |
| US5580715A (en) | 1994-08-05 | 1996-12-03 | The Regents Of The University Of California | Diagnosis of cancer having clonal macrophage involvement |
| US5639600A (en) | 1994-08-05 | 1997-06-17 | The Regents Of The University Of California | Diagnosis and treatment of cell proliferative disease having clonal macrophage involvement |
| US5698563A (en) | 1995-01-13 | 1997-12-16 | Alteon Inc. | Bis- hydrazones! |
| ATE294583T1 (de) | 1996-09-13 | 2005-05-15 | Univ Florida | Verfahren zur hemmung von eif5a-biosynthese |
| AR009380A1 (es) | 1996-10-21 | 2000-04-12 | Sumitomo Chemical Co | Proceso de preparacion de un derivado de piridazin-3-ona, util como herbicida, acido carboxilico de utilizacion en el mismo, sal de este ultimo y proceso para preparar dicho acido carboxilico |
| US6083496A (en) | 1996-10-22 | 2000-07-04 | Universite Laval | Polyamine transport inhibitors |
| AU758570B2 (en) | 1997-07-15 | 2003-03-27 | Mediquest Therapeutics, Inc. | Novel polyamine analogues as therapeutic and diagnostic agents |
| US5889061A (en) | 1997-10-15 | 1999-03-30 | Wisconsin Alumni Research Foundation | Conformationally restricted polyamines |
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