SG10201810888XA - Compositions and methods comprising bupropion or related compounds and dextromethorphan - Google Patents

Compositions and methods comprising bupropion or related compounds and dextromethorphan

Info

Publication number
SG10201810888XA
SG10201810888XA SG10201810888XA SG10201810888XA SG10201810888XA SG 10201810888X A SG10201810888X A SG 10201810888XA SG 10201810888X A SG10201810888X A SG 10201810888XA SG 10201810888X A SG10201810888X A SG 10201810888XA SG 10201810888X A SG10201810888X A SG 10201810888XA
Authority
SG
Singapore
Prior art keywords
dextromethorphan
bupropion
compositions
methods
related compounds
Prior art date
Application number
SG10201810888XA
Inventor
Herriot Tabuteau
Original Assignee
Antecip Bioventures Ii Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Antecip Bioventures Ii Llc filed Critical Antecip Bioventures Ii Llc
Publication of SG10201810888XA publication Critical patent/SG10201810888XA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/485Morphinan derivatives, e.g. morphine, codeine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/14Antitussive agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Abstract

COMPOSITIONS AND METHODS COMPRISING BUPROPION OR RELATED COMPOUNDS AND DEXTROMETHORPHAN This disclosure relates to a method of treating a neurological disorder by administering an antidepressant compound and dextromethorphan to a human being in need thereof. This may useful human that extensive etabolizers dextromethorphan. medicaments, dosage comprising antidepressant and omethorphan also d. Figure 7
SG10201810888XA 2013-11-05 2014-11-05 Compositions and methods comprising bupropion or related compounds and dextromethorphan SG10201810888XA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201361900354P 2013-11-05 2013-11-05

Publications (1)

Publication Number Publication Date
SG10201810888XA true SG10201810888XA (en) 2019-01-30

Family

ID=53042051

Family Applications (4)

Application Number Title Priority Date Filing Date
SG11201603391XA SG11201603391XA (en) 2013-11-05 2014-11-05 Compositions and methods comprising bupropion or related compounds and dextromethorphan
SG10201810888XA SG10201810888XA (en) 2013-11-05 2014-11-05 Compositions and methods comprising bupropion or related compounds and dextromethorphan
SG10201911808QA SG10201911808QA (en) 2013-11-05 2014-11-05 Compositions and methods comprising bupropion or related compounds and dextromethorphan
SG10201911816XA SG10201911816XA (en) 2013-11-05 2014-11-05 Compositions and methods comprising bupropion or related compounds and dextromethorphan

Family Applications Before (1)

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SG11201603391XA SG11201603391XA (en) 2013-11-05 2014-11-05 Compositions and methods comprising bupropion or related compounds and dextromethorphan

Family Applications After (2)

Application Number Title Priority Date Filing Date
SG10201911808QA SG10201911808QA (en) 2013-11-05 2014-11-05 Compositions and methods comprising bupropion or related compounds and dextromethorphan
SG10201911816XA SG10201911816XA (en) 2013-11-05 2014-11-05 Compositions and methods comprising bupropion or related compounds and dextromethorphan

Country Status (12)

Country Link
EP (3) EP3981404A1 (en)
JP (4) JP6605485B2 (en)
KR (4) KR20230148385A (en)
CN (7) CN110279682A (en)
AU (6) AU2014346807B2 (en)
CA (3) CA3154845C (en)
IL (3) IL298972A (en)
MX (3) MX2016005867A (en)
MY (1) MY179696A (en)
NZ (5) NZ758431A (en)
SG (4) SG11201603391XA (en)
WO (1) WO2015069809A1 (en)

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CA3154845C (en) * 2013-11-05 2023-02-28 Antecip Bioventures Ii Llc Compositions and methods comprising bupropion or related compounds and dextromethorphan
US11497721B2 (en) 2013-11-05 2022-11-15 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
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US11197839B2 (en) 2013-11-05 2021-12-14 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US20200338022A1 (en) 2019-01-07 2020-10-29 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11253492B2 (en) 2013-11-05 2022-02-22 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11291665B2 (en) 2013-11-05 2022-04-05 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11191739B2 (en) 2013-11-05 2021-12-07 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11439636B1 (en) 2013-11-05 2022-09-13 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
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US11426401B2 (en) 2013-11-05 2022-08-30 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11534414B2 (en) 2013-11-05 2022-12-27 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11382874B2 (en) 2013-11-05 2022-07-12 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11357744B2 (en) 2013-11-05 2022-06-14 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11207281B2 (en) 2013-11-05 2021-12-28 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11478468B2 (en) 2013-11-05 2022-10-25 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11147808B2 (en) 2013-11-05 2021-10-19 Antecip Bioventures Ii Llc Method of decreasing the fluctuation index of dextromethorphan
US11590124B2 (en) 2013-11-05 2023-02-28 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11285118B2 (en) 2013-11-05 2022-03-29 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11510918B2 (en) 2013-11-05 2022-11-29 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11571417B2 (en) 2013-11-05 2023-02-07 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11419867B2 (en) 2013-11-05 2022-08-23 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11344544B2 (en) 2013-11-05 2022-05-31 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11364233B2 (en) 2013-11-05 2022-06-21 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US20220233470A1 (en) 2013-11-05 2022-07-28 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11576909B2 (en) 2013-11-05 2023-02-14 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11433067B2 (en) 2013-11-05 2022-09-06 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11571399B2 (en) 2013-11-05 2023-02-07 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11617728B2 (en) 2013-11-05 2023-04-04 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11596627B2 (en) 2013-11-05 2023-03-07 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11273133B2 (en) 2013-11-05 2022-03-15 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11541048B2 (en) 2013-11-05 2023-01-03 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11311534B2 (en) 2013-11-05 2022-04-26 Antecip Bio Ventures Ii Llc Bupropion as a modulator of drug activity
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US11129826B2 (en) 2013-11-05 2021-09-28 Axsome Therapeutics, Inc. Bupropion as a modulator of drug activity
US11576877B2 (en) 2013-11-05 2023-02-14 Antecip Bioventures Ii Llc Bupropion as modulator of drug activity
US11234946B2 (en) 2013-11-05 2022-02-01 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
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TW202231278A (en) * 2014-09-14 2022-08-16 美商阿瓦尼爾製藥股份有限公司 Pharmaceutical compositions comprising a dextromethorphan compound and quinidine for the treatment of agitation in dementia
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CN114340608B (en) * 2020-07-20 2023-10-31 深圳信立泰药业股份有限公司 Pharmaceutical composition and application thereof
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Publication number Publication date
EP3065742A1 (en) 2016-09-14
AU2014346807A1 (en) 2016-05-19
NZ719892A (en) 2021-07-30
CN106163522A (en) 2016-11-23
CN110327338A (en) 2019-10-15
JP6927601B2 (en) 2021-09-01
AU2018203638B2 (en) 2019-07-18
KR20160070158A (en) 2016-06-17
CN113750099A (en) 2021-12-07
CN113750098A (en) 2021-12-07
NZ758428A (en) 2021-07-30
KR102603013B1 (en) 2023-11-15
KR102264179B1 (en) 2021-06-11
KR20210068157A (en) 2021-06-08
IL298972A (en) 2023-02-01
AU2014346807B2 (en) 2018-03-22
JP2016535786A (en) 2016-11-17
AU2019236614B2 (en) 2021-07-15
IL283760B1 (en) 2023-01-01
JP2020023543A (en) 2020-02-13
CA3154845C (en) 2023-02-28
MY179696A (en) 2020-11-11
MX2020004075A (en) 2021-12-10
EP3981403A1 (en) 2022-04-13
AU2019275593B2 (en) 2021-01-28
EP3981404A1 (en) 2022-04-13
JP6605485B2 (en) 2019-11-13
SG10201911816XA (en) 2020-01-30
AU2021202497A1 (en) 2021-05-27
CN110251517A (en) 2019-09-20
AU2019275593A1 (en) 2020-01-02
NZ758432A (en) 2021-07-30
MX2016005867A (en) 2016-07-15
KR20220054909A (en) 2022-05-03
AU2021202497B2 (en) 2023-03-02
EP3065742A4 (en) 2017-04-05
NZ758425A (en) 2021-07-30
JP2023129646A (en) 2023-09-14
MX2021015234A (en) 2022-05-26
AU2019236614A1 (en) 2019-10-17
CN110279682A (en) 2019-09-27
AU2018203638A1 (en) 2018-06-14
CA3154845A1 (en) 2015-05-14
IL245504B (en) 2021-06-30
SG10201911808QA (en) 2020-01-30
WO2015069809A1 (en) 2015-05-14
CA2929415A1 (en) 2015-05-14
CN113797205A (en) 2021-12-17
KR20230148385A (en) 2023-10-24
SG11201603391XA (en) 2016-05-30
CA3175703A1 (en) 2015-05-14
IL245504A0 (en) 2016-06-30
NZ758431A (en) 2021-07-30
AU2023203438A1 (en) 2023-07-06
CA2929415C (en) 2023-01-03
JP2021169527A (en) 2021-10-28
AU2018203638C1 (en) 2019-10-24
IL283760A (en) 2021-07-29
AU2019236614C1 (en) 2021-10-14
IL283760B2 (en) 2023-05-01

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