NZ630091A - Immunofluorescence and fluorescent-based nucleic acid analysis on a single sample - Google Patents

Immunofluorescence and fluorescent-based nucleic acid analysis on a single sample

Info

Publication number
NZ630091A
NZ630091A NZ630091A NZ63009113A NZ630091A NZ 630091 A NZ630091 A NZ 630091A NZ 630091 A NZ630091 A NZ 630091A NZ 63009113 A NZ63009113 A NZ 63009113A NZ 630091 A NZ630091 A NZ 630091A
Authority
NZ
New Zealand
Prior art keywords
sample
image
generating
nucleic acid
fluorescent
Prior art date
Application number
NZ630091A
Other languages
English (en)
Inventor
Antti E Seppo
Fiona Ginty
Kevin B Kenny
David Lavan Henderson
Michael J Gerdes
Moreno Adriana I Larriera
Alex D Corwin
Stephen E Zingelewicz
Thomas Ha
Natalie R Jun
Denise A Hollman-Hewgley
Ying Li
Xiaofeng Liu
Ainura Kyshtoobayeve
Original Assignee
Ge Healthcare Bio Sciences
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ge Healthcare Bio Sciences filed Critical Ge Healthcare Bio Sciences
Publication of NZ630091A publication Critical patent/NZ630091A/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5752Immunoassay; Biospecific binding assay; Materials therefor for cancer of the lungs
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N21/6456Spatial resolved fluorescence measurements; Imaging
    • G01N21/6458Fluorescence microscopy
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57515Immunoassay; Biospecific binding assay; Materials therefor for cancer of the breast
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/71Assays involving receptors, cell surface antigens or cell surface determinants for growth factors; for growth regulators

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Optics & Photonics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Peptides Or Proteins (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
NZ630091A 2012-03-30 2013-03-21 Immunofluorescence and fluorescent-based nucleic acid analysis on a single sample NZ630091A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261618132P 2012-03-30 2012-03-30
PCT/US2013/033249 WO2013148448A1 (en) 2012-03-30 2013-03-21 Immunoflu0rescence and fluorescent-based nucleic acid analysis on a single sample

Publications (1)

Publication Number Publication Date
NZ630091A true NZ630091A (en) 2016-03-31

Family

ID=48050953

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ630091A NZ630091A (en) 2012-03-30 2013-03-21 Immunofluorescence and fluorescent-based nucleic acid analysis on a single sample

Country Status (12)

Country Link
US (2) US20150065371A1 (https=)
EP (1) EP2831591B1 (https=)
JP (1) JP6225163B2 (https=)
KR (1) KR20140142715A (https=)
CN (1) CN104520713A (https=)
AU (1) AU2013240127B2 (https=)
CA (1) CA2867508C (https=)
IN (1) IN2014DN07531A (https=)
NZ (1) NZ630091A (https=)
RU (1) RU2014137129A (https=)
SG (1) SG11201406105UA (https=)
WO (1) WO2013148448A1 (https=)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10787701B2 (en) 2010-04-05 2020-09-29 Prognosys Biosciences, Inc. Spatially encoded biological assays
CN108267581A (zh) 2012-08-24 2018-07-10 耶鲁大学 用于高通量多重检测的系统、装置和方法
US10088658B2 (en) 2013-03-18 2018-10-02 General Electric Company Referencing in multi-acquisition slide imaging
JP6605506B2 (ja) * 2014-02-24 2019-11-13 ヴェンタナ メディカル システムズ, インク. CD3、CD8、CD20及びFoxP3の同時検出によりがんに対する免疫応答をスコア化するための方法、キット、及びシステム
CN104980558B (zh) * 2014-04-01 2019-01-01 中国移动通信集团公司 一种信息处理的方法、装置、手机宠物客户端及移动终端
WO2015157246A2 (en) * 2014-04-07 2015-10-15 Massachusetts Institute Of Technology Use of microparticle additives to simultaneously enable artifact-free image registration, auto-focusing, and chromatic aberration correction in microscopy
WO2016026038A1 (en) * 2014-08-18 2016-02-25 Viewsiq Inc. System and method for embedded images in large field-of-view microscopic scans
CN112782140A (zh) * 2014-12-03 2021-05-11 伊索普莱西斯公司 细胞分泌特征的分析和筛选
US11353448B2 (en) 2015-02-13 2022-06-07 California Institute Of Technology Methods and compositions for quantifying metabolites and proteins from single cells
WO2017012555A1 (zh) * 2015-07-20 2017-01-26 徐敏 光子结构和化学计量学病理系统
EP3396375B1 (en) * 2015-12-24 2021-08-04 Konica Minolta, Inc. Image processing device and program
CN107419001A (zh) * 2016-05-23 2017-12-01 益善生物技术股份有限公司 Brca1、pten基因异常检测试剂盒及检测方法
JP6231709B1 (ja) * 2016-05-31 2017-11-15 シスメックス株式会社 蛍光画像分析装置および分析方法
EP3469548B1 (en) 2016-06-10 2020-05-13 H. Hoffnabb-La Roche Ag System for bright field image simulation
CN106290878A (zh) * 2016-09-10 2017-01-04 天津大学 基于量子点的胰腺癌肿瘤标志物ca242免疫层析试纸条的制备方法
EP3510398B1 (en) 2016-09-12 2026-02-25 Isoplexis Corporation System and methods for multiplexed analysis of cellular and other immunotherapeutics
CA3034924C (en) * 2016-09-26 2025-11-18 Becton, Dickinson And Company MEASUREMENT OF PROTEIN EXPRESSION USING REAGENTS WITH BARCODED OLIGONUCLEOTIDE SEQUENCES
EP4036578A1 (en) 2016-11-11 2022-08-03 Isoplexis Corporation Compositions and methods for the simultaneous genomic, transcriptomic and proteomic analysis of single cells
CN110226084A (zh) 2016-11-22 2019-09-10 伊索普莱克西斯公司 用于细胞捕获的系统、装置和方法,以及其制造方法
CN112601950B (zh) * 2018-08-22 2023-07-28 仪景通株式会社 图像处理装置、摄像系统、图像处理装置的工作方法以及图像处理装置的工作程序
US10921223B2 (en) * 2018-10-12 2021-02-16 Shenzhen Prs Limited Process record slide for staining and method of using the same
CN110498858B (zh) * 2019-07-26 2024-01-23 深圳市达科为生物工程有限公司 一种动态检测单细胞外泌蛋白分泌情况的方法
US20210182531A1 (en) * 2019-12-17 2021-06-17 Applied Materials, Inc. Registration techniques for multiplexed fluorescence in-situ hybridization images
EP4147044A4 (en) * 2020-05-07 2024-06-12 Advanced Cell Diagnostics, Inc. METHOD FOR THE SIMULTANEOUS DETECTION OF TARGET NUCLEIC ACIDS AND PROTEINS AND KIT THEREFOR
US12235215B2 (en) * 2020-07-20 2025-02-25 Akoya Biosciences, Inc. Processing and imaging tissue samples
WO2022035943A1 (en) * 2020-08-13 2022-02-17 Ventana Medical Systems, Inc. Automated identification of necrotic regions in digital images of multiplex immunofluorescence stained tissue
EP4491742B1 (en) * 2020-09-18 2026-03-04 10X Genomics, Inc. Sample handling apparatus and image registration methods
CN112415198B (zh) * 2020-11-20 2022-11-11 四川大学华西医院 Gp1bb检测试剂在制备肺癌筛查试剂盒中的用途
CN113310963B (zh) * 2021-05-31 2023-12-01 四川大学华西医院 一种改进的中性粒细胞NETs免疫荧光检测方法
US20250000906A1 (en) 2021-11-16 2025-01-02 Sotio Biotech Inc. Treatment of myxoid/round cell liposarcoma patients
US20250216394A1 (en) * 2022-01-28 2025-07-03 University Of Southern California Liquid biopsy analytes to define cancer stages
EP4469788A4 (en) * 2022-01-28 2025-12-24 Univ Southern California IDENTIFICATION OF NON-DISEALED PATIENTS USING DISEASE-ASSOCIATED ASSAY AND ANALYSIS IN LIQUID BIOPSY

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6404906B2 (en) 1997-03-03 2002-06-11 Bacus Research Laboratories,Inc. Method and apparatus for acquiring and reconstructing magnified specimen images from a computer-controlled microscope
US6993169B2 (en) * 2001-01-11 2006-01-31 Trestle Corporation System and method for finding regions of interest for microscopic digital montage imaging
US7629125B2 (en) * 2006-11-16 2009-12-08 General Electric Company Sequential analysis of biological samples
US20110189670A1 (en) * 2008-07-07 2011-08-04 Ruth L Katz Circulating Tumor and Tumor Stem Cell Detection Using Genomic Specific Probes
US8269827B2 (en) * 2009-09-29 2012-09-18 General Electric Company System and methods for mapping fluorescent images into a bright field color space

Also Published As

Publication number Publication date
KR20140142715A (ko) 2014-12-12
WO2013148448A1 (en) 2013-10-03
RU2014137129A (ru) 2016-05-27
JP2015514212A (ja) 2015-05-18
CN104520713A (zh) 2015-04-15
IN2014DN07531A (https=) 2015-04-24
US20150065371A1 (en) 2015-03-05
AU2013240127B2 (en) 2018-07-12
US20250102507A1 (en) 2025-03-27
AU2013240127A1 (en) 2014-10-02
SG11201406105UA (en) 2014-10-30
CA2867508A1 (en) 2013-10-03
EP2831591B1 (en) 2019-05-08
JP6225163B2 (ja) 2017-11-01
EP2831591A1 (en) 2015-02-04
CA2867508C (en) 2021-05-18

Similar Documents

Publication Publication Date Title
NZ630091A (en) Immunofluorescence and fluorescent-based nucleic acid analysis on a single sample
Ma et al. Profiling chromatin regulatory landscape: insights into the development of ChIP-seq and ATAC-seq
Simoni et al. Mass cytometry: a powerful tool for dissecting the immune landscape
Füllgrabe et al. Dynamics of Lgr6+ progenitor cells in the hair follicle, sebaceous gland, and interfollicular epidermis
Ren et al. Single‐Cell Imaging of m6A Modified RNA Using m6A‐Specific In Situ Hybridization Mediated Proximity Ligation Assay (m6AISH‐PLA)
EP4282977A3 (en) Spatially distinguished, multiplex nucleic acid analysis of biological specimens
ES2715018T3 (es) Ensayo múltiple para puntuar mejor los tejidos tumorales teñidos para PD-L1
RU2014137125A (ru) Способы формирования изображения биологического образца
ATE445841T1 (de) Verfahren zur spezifischen detektion von tumorzellen und ihren vorstufen in gebärmutterhalsabstrichen durch simultane messung von mindestens 2 verschiedenen molekularen markern
JP2015514213A5 (https=)
WO2011146629A3 (en) Methods and compositions for sequence-specific purification and multiplex analysis of nucleic acids
WO2011034690A3 (en) Centroid markers for image analysis of high density clusters in complex polynucleotide sequencing
Wang et al. Spatial transcriptomics: recent developments and insights in respiratory research
EP2495334A4 (en) PROCESS FOR DETECTING TARGET NUCLEIC ACIDS
MX382296B (es) Sistema y método para la detección de alto rendimiento de células cancerígenas.
WO2008128043A3 (en) Diagnostic and prognostic methods for renal cell carcinoma
Kadam et al. Gene expression analysis using conventional and imaging methods
WO2009151757A3 (en) Method and apparatus for forensic screening
ATE545017T1 (de) Kumulative zeitaufgelöste emission von zweidimensionaler gelelektrophorese
McMahon Avidin-biotin interactions: methods and applications
Sarkar et al. Isothermal amplification strategies for detection in microfluidic devices
WO2019078684A3 (ko) 감각신경성 난청 진단을 위한 마커 tmem43 및 그의 용도
ATE452208T1 (de) Verfahren zum nachweis einer zielsubstanz unter verwendung einer nukleinsäuresonde
Ugur et al. Locus-specific chromatin proteome revealed by mass spectrometry-based CasID
WO2008104984A3 (en) Diagnosis and prognosis of various types of cancers

Legal Events

Date Code Title Description
ASS Change of ownership

Owner name: GE HEALTHCARE BIO-SCIENCES CORP., US

Effective date: 20160128

PSEA Patent sealed
LAPS Patent lapsed