SG11201406105UA - Immunofluorescence and fluorescent-based nucleic acid analysis on a single sample - Google Patents
Immunofluorescence and fluorescent-based nucleic acid analysis on a single sampleInfo
- Publication number
- SG11201406105UA SG11201406105UA SG11201406105UA SG11201406105UA SG11201406105UA SG 11201406105U A SG11201406105U A SG 11201406105UA SG 11201406105U A SG11201406105U A SG 11201406105UA SG 11201406105U A SG11201406105U A SG 11201406105UA SG 11201406105U A SG11201406105U A SG 11201406105UA
- Authority
- SG
- Singapore
- Prior art keywords
- immunofluorescence
- fluorescent
- nucleic acid
- acid analysis
- single sample
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/5752—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the lungs
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N21/6456—Spatial resolved fluorescence measurements; Imaging
- G01N21/6458—Fluorescence microscopy
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57515—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the breast
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/71—Assays involving receptors, cell surface antigens or cell surface determinants for growth factors; for growth regulators
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- General Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Optics & Photonics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261618132P | 2012-03-30 | 2012-03-30 | |
| PCT/US2013/033249 WO2013148448A1 (en) | 2012-03-30 | 2013-03-21 | Immunoflu0rescence and fluorescent-based nucleic acid analysis on a single sample |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201406105UA true SG11201406105UA (en) | 2014-10-30 |
Family
ID=48050953
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201406105UA SG11201406105UA (en) | 2012-03-30 | 2013-03-21 | Immunofluorescence and fluorescent-based nucleic acid analysis on a single sample |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US20150065371A1 (https=) |
| EP (1) | EP2831591B1 (https=) |
| JP (1) | JP6225163B2 (https=) |
| KR (1) | KR20140142715A (https=) |
| CN (1) | CN104520713A (https=) |
| AU (1) | AU2013240127B2 (https=) |
| CA (1) | CA2867508C (https=) |
| IN (1) | IN2014DN07531A (https=) |
| NZ (1) | NZ630091A (https=) |
| RU (1) | RU2014137129A (https=) |
| SG (1) | SG11201406105UA (https=) |
| WO (1) | WO2013148448A1 (https=) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10787701B2 (en) | 2010-04-05 | 2020-09-29 | Prognosys Biosciences, Inc. | Spatially encoded biological assays |
| EP4148118A1 (en) | 2012-08-24 | 2023-03-15 | Yale University | System, device and method for high-throughput multi-plexed detection |
| US10088658B2 (en) | 2013-03-18 | 2018-10-02 | General Electric Company | Referencing in multi-acquisition slide imaging |
| CA2940115C (en) | 2014-02-24 | 2023-03-14 | Ventana Medical Systems, Inc. | Methods, kits, and systems for scoring the immune response to cancer by simultaneous detection of cd3, cd8, cd20 and foxp3 |
| CN104980558B (zh) * | 2014-04-01 | 2019-01-01 | 中国移动通信集团公司 | 一种信息处理的方法、装置、手机宠物客户端及移动终端 |
| WO2015157246A2 (en) * | 2014-04-07 | 2015-10-15 | Massachusetts Institute Of Technology | Use of microparticle additives to simultaneously enable artifact-free image registration, auto-focusing, and chromatic aberration correction in microscopy |
| WO2016026038A1 (en) * | 2014-08-18 | 2016-02-25 | Viewsiq Inc. | System and method for embedded images in large field-of-view microscopic scans |
| US10584366B2 (en) | 2014-12-03 | 2020-03-10 | IsoPlexis Corporation | Analysis and screening of cell secretion profiles |
| US11353448B2 (en) | 2015-02-13 | 2022-06-07 | California Institute Of Technology | Methods and compositions for quantifying metabolites and proteins from single cells |
| CN107847145B (zh) * | 2015-07-20 | 2020-08-14 | 徐敏 | 光子结构和化学计量学病理系统 |
| EP3396375B1 (en) * | 2015-12-24 | 2021-08-04 | Konica Minolta, Inc. | Image processing device and program |
| CN107419001A (zh) * | 2016-05-23 | 2017-12-01 | 益善生物技术股份有限公司 | Brca1、pten基因异常检测试剂盒及检测方法 |
| JP6231709B1 (ja) * | 2016-05-31 | 2017-11-15 | シスメックス株式会社 | 蛍光画像分析装置および分析方法 |
| WO2017212055A1 (en) * | 2016-06-10 | 2017-12-14 | F. Hoffmann-La Roche Ag | System for bright field image simulation |
| CN106290878A (zh) * | 2016-09-10 | 2017-01-04 | 天津大学 | 基于量子点的胰腺癌肿瘤标志物ca242免疫层析试纸条的制备方法 |
| WO2018049418A1 (en) | 2016-09-12 | 2018-03-15 | IsoPlexis Corporation | System and methods for multiplexed analysis of cellular and other immunotherapeutics |
| CN109791157B (zh) * | 2016-09-26 | 2022-06-07 | 贝克顿迪金森公司 | 使用具有条形码化的寡核苷酸序列的试剂测量蛋白质表达 |
| EP3538891B1 (en) | 2016-11-11 | 2022-01-05 | Isoplexis Corporation | Compositions and methods for the simultaneous genomic, transcriptomic and proteomic analysis of single cells |
| US11525783B2 (en) | 2016-11-22 | 2022-12-13 | IsoPlexis Corporation | Systems, devices and methods for cell capture and methods of manufacture thereof |
| WO2020039520A1 (ja) * | 2018-08-22 | 2020-02-27 | オリンパス株式会社 | 画像処理装置、撮像システム、画像処理装置の作動方法、及び画像処理装置の作動プログラム |
| US10921223B2 (en) * | 2018-10-12 | 2021-02-16 | Shenzhen Prs Limited | Process record slide for staining and method of using the same |
| CN110498858B (zh) * | 2019-07-26 | 2024-01-23 | 深圳市达科为生物工程有限公司 | 一种动态检测单细胞外泌蛋白分泌情况的方法 |
| US20210182531A1 (en) * | 2019-12-17 | 2021-06-17 | Applied Materials, Inc. | Registration techniques for multiplexed fluorescence in-situ hybridization images |
| EP4147044A4 (en) * | 2020-05-07 | 2024-06-12 | Advanced Cell Diagnostics, Inc. | METHOD FOR THE SIMULTANEOUS DETECTION OF TARGET NUCLEIC ACIDS AND PROTEINS AND KIT THEREFOR |
| EP4182676A1 (en) * | 2020-07-20 | 2023-05-24 | Akoya Biosciences, Inc. | Processing and imaging tissue samples |
| WO2022035943A1 (en) | 2020-08-13 | 2022-02-17 | Ventana Medical Systems, Inc. | Automated identification of necrotic regions in digital images of multiplex immunofluorescence stained tissue |
| WO2022061150A2 (en) * | 2020-09-18 | 2022-03-24 | 10X Geonomics, Inc. | Sample handling apparatus and image registration methods |
| CN112415198B (zh) * | 2020-11-20 | 2022-11-11 | 四川大学华西医院 | Gp1bb检测试剂在制备肺癌筛查试剂盒中的用途 |
| CN113310963B (zh) * | 2021-05-31 | 2023-12-01 | 四川大学华西医院 | 一种改进的中性粒细胞NETs免疫荧光检测方法 |
| AU2022388928A1 (en) | 2021-11-16 | 2024-05-16 | Sotio Biotech Inc. | Treatment of myxoid/round cell liposarcoma patients |
| WO2023147133A1 (en) * | 2022-01-28 | 2023-08-03 | University Of Southern California | Liquid biopsy analytes to define cancer stages |
| CA3243342A1 (en) * | 2022-01-28 | 2023-08-03 | University Of Southern California | IDENTIFICATION OF NON-DISEALED PATIENTS USING DISEASE-ASSOCIATED ASSAY AND ANALYSIS IN LIQUID BIOPSY |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6404906B2 (en) | 1997-03-03 | 2002-06-11 | Bacus Research Laboratories,Inc. | Method and apparatus for acquiring and reconstructing magnified specimen images from a computer-controlled microscope |
| US6993169B2 (en) * | 2001-01-11 | 2006-01-31 | Trestle Corporation | System and method for finding regions of interest for microscopic digital montage imaging |
| US7629125B2 (en) * | 2006-11-16 | 2009-12-08 | General Electric Company | Sequential analysis of biological samples |
| US20110189670A1 (en) * | 2008-07-07 | 2011-08-04 | Ruth L Katz | Circulating Tumor and Tumor Stem Cell Detection Using Genomic Specific Probes |
| US8269827B2 (en) * | 2009-09-29 | 2012-09-18 | General Electric Company | System and methods for mapping fluorescent images into a bright field color space |
-
2013
- 2013-03-21 JP JP2015503378A patent/JP6225163B2/ja active Active
- 2013-03-21 EP EP13715086.8A patent/EP2831591B1/en active Active
- 2013-03-21 CA CA2867508A patent/CA2867508C/en active Active
- 2013-03-21 RU RU2014137129A patent/RU2014137129A/ru not_active Application Discontinuation
- 2013-03-21 CN CN201380017702.4A patent/CN104520713A/zh active Pending
- 2013-03-21 KR KR20147027562A patent/KR20140142715A/ko not_active Withdrawn
- 2013-03-21 NZ NZ630091A patent/NZ630091A/en not_active IP Right Cessation
- 2013-03-21 IN IN7531DEN2014 patent/IN2014DN07531A/en unknown
- 2013-03-21 US US14/387,861 patent/US20150065371A1/en not_active Abandoned
- 2013-03-21 WO PCT/US2013/033249 patent/WO2013148448A1/en not_active Ceased
- 2013-03-21 SG SG11201406105UA patent/SG11201406105UA/en unknown
- 2013-03-21 AU AU2013240127A patent/AU2013240127B2/en active Active
-
2024
- 2024-08-30 US US18/820,303 patent/US20250102507A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP6225163B2 (ja) | 2017-11-01 |
| IN2014DN07531A (https=) | 2015-04-24 |
| CN104520713A (zh) | 2015-04-15 |
| KR20140142715A (ko) | 2014-12-12 |
| AU2013240127B2 (en) | 2018-07-12 |
| US20150065371A1 (en) | 2015-03-05 |
| CA2867508C (en) | 2021-05-18 |
| US20250102507A1 (en) | 2025-03-27 |
| NZ630091A (en) | 2016-03-31 |
| AU2013240127A1 (en) | 2014-10-02 |
| EP2831591A1 (en) | 2015-02-04 |
| EP2831591B1 (en) | 2019-05-08 |
| RU2014137129A (ru) | 2016-05-27 |
| WO2013148448A1 (en) | 2013-10-03 |
| JP2015514212A (ja) | 2015-05-18 |
| CA2867508A1 (en) | 2013-10-03 |
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