NZ629730A - Compositions and their use to treat complications of aneurysmal subarachnoid hemorrhage - Google Patents
Compositions and their use to treat complications of aneurysmal subarachnoid hemorrhageInfo
- Publication number
- NZ629730A NZ629730A NZ629730A NZ62973014A NZ629730A NZ 629730 A NZ629730 A NZ 629730A NZ 629730 A NZ629730 A NZ 629730A NZ 62973014 A NZ62973014 A NZ 62973014A NZ 629730 A NZ629730 A NZ 629730A
- Authority
- NZ
- New Zealand
- Prior art keywords
- compositions
- aneurysmal subarachnoid
- treat complications
- subarachnoid hemorrhage
- kda
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 208000032851 Subarachnoid Hemorrhage Diseases 0.000 title abstract 2
- 229920001606 poly(lactic acid-co-glycolic acid) Polymers 0.000 abstract 2
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 abstract 1
- UIAGMCDKSXEBJQ-IBGZPJMESA-N 3-o-(2-methoxyethyl) 5-o-propan-2-yl (4s)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate Chemical compound COCCOC(=O)C1=C(C)NC(C)=C(C(=O)OC(C)C)[C@H]1C1=CC=CC([N+]([O-])=O)=C1 UIAGMCDKSXEBJQ-IBGZPJMESA-N 0.000 abstract 1
- 206010047163 Vasospasm Diseases 0.000 abstract 1
- 229920002674 hyaluronan Polymers 0.000 abstract 1
- 229960003160 hyaluronic acid Drugs 0.000 abstract 1
- 239000011859 microparticle Substances 0.000 abstract 1
- 229960000715 nimodipine Drugs 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4418—Non condensed pyridines; Hydrogenated derivatives thereof having a carbocyclic group directly attached to the heterocyclic ring, e.g. cyproheptadine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0085—Brain, e.g. brain implants; Spinal cord
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Psychology (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Inorganic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13/793,767 US10092524B2 (en) | 2008-06-11 | 2013-03-11 | Compositions and their use to treat complications of aneurysmal subarachnoid hemorrhage |
| PCT/US2014/023748 WO2014164904A1 (en) | 2013-03-11 | 2014-03-11 | Compositions and their use to treat complications of aneurysmal subarachnoid hemorrhage |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ629730A true NZ629730A (en) | 2017-03-31 |
Family
ID=49157870
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ629730A NZ629730A (en) | 2013-03-11 | 2014-03-11 | Compositions and their use to treat complications of aneurysmal subarachnoid hemorrhage |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US10092524B2 (enExample) |
| EP (1) | EP2968166A4 (enExample) |
| JP (1) | JP2016512527A (enExample) |
| KR (1) | KR101902319B1 (enExample) |
| CN (1) | CN105324108A (enExample) |
| AU (1) | AU2014248877A1 (enExample) |
| BR (1) | BR112015022218A2 (enExample) |
| CA (1) | CA2905327A1 (enExample) |
| GB (1) | GB2528801A (enExample) |
| HK (1) | HK1216002A1 (enExample) |
| NZ (1) | NZ629730A (enExample) |
| RU (1) | RU2015143206A (enExample) |
| SG (1) | SG11201507398XA (enExample) |
| WO (1) | WO2014164904A1 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9364432B2 (en) | 2007-06-11 | 2016-06-14 | Edge Therapeutics, Inc. | Intraventricular drug delivery system for improving outcome after a brain injury affecting cerebral blood flow |
| US10092524B2 (en) | 2008-06-11 | 2018-10-09 | Edge Therapeutics, Inc. | Compositions and their use to treat complications of aneurysmal subarachnoid hemorrhage |
| GB2556500A (en) * | 2015-05-29 | 2018-05-30 | Edge Therapeutics Inc | Compositions and methods for reducing visual loss |
| WO2017176914A1 (en) * | 2016-04-07 | 2017-10-12 | Edge Therapeutics, Inc. | Formulations of site-specific, microparticulate compositions and their use to improve outcome after aneurysmal subarachnoid hemorrhage |
| CN108403629B (zh) * | 2018-04-26 | 2019-11-05 | 徐州医科大学 | 一种尼莫地平口服长效悬浮液及其制备方法 |
| WO2020227558A2 (en) * | 2019-05-07 | 2020-11-12 | Yale University | Maximizing distribution and minimizing washout of injectates in bone and method for enhanced aspirate extraction |
| KR102425548B1 (ko) * | 2019-05-22 | 2022-07-26 | 경북대학교 산학협력단 | Cacb1 유래 펩타이드, Cacb1 유래 펩타이드의 변이체 및 이의 용도 |
| US20210260334A1 (en) * | 2020-02-20 | 2021-08-26 | Postsurgical Therapeutics, Inc. | Brain drug delivery system and method |
| WO2021262725A1 (en) * | 2020-06-22 | 2021-12-30 | Curelator, Inc. | Systems and methods for segmentation of a user population based on time-based variations in biomarker levels |
| US11452690B1 (en) | 2021-01-27 | 2022-09-27 | ECI Pharmaceuticals, LLC | Oral liquid compositions comprising amlodipine besylate and methods of using the same |
| JP2024508888A (ja) * | 2021-03-03 | 2024-02-28 | クランメド リミテッド | 一時的塞栓剤としてのアルギネートベースの粒子 |
| WO2025151741A1 (en) * | 2024-01-10 | 2025-07-17 | Brown David Donaldson | Methods of treating migraine headache or tension headache with hyaluronic acid |
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-
2013
- 2013-03-11 US US13/793,767 patent/US10092524B2/en not_active Expired - Fee Related
-
2014
- 2014-03-11 AU AU2014248877A patent/AU2014248877A1/en not_active Abandoned
- 2014-03-11 WO PCT/US2014/023748 patent/WO2014164904A1/en not_active Ceased
- 2014-03-11 SG SG11201507398XA patent/SG11201507398XA/en unknown
- 2014-03-11 HK HK16103935.4A patent/HK1216002A1/zh unknown
- 2014-03-11 GB GB1516997.2A patent/GB2528801A/en not_active Withdrawn
- 2014-03-11 EP EP14780318.3A patent/EP2968166A4/en not_active Withdrawn
- 2014-03-11 NZ NZ629730A patent/NZ629730A/en not_active IP Right Cessation
- 2014-03-11 RU RU2015143206A patent/RU2015143206A/ru not_active Application Discontinuation
- 2014-03-11 BR BR112015022218A patent/BR112015022218A2/pt not_active IP Right Cessation
- 2014-03-11 JP JP2016501330A patent/JP2016512527A/ja active Pending
- 2014-03-11 CN CN201480026815.5A patent/CN105324108A/zh active Pending
- 2014-03-11 KR KR1020157028454A patent/KR101902319B1/ko not_active Expired - Fee Related
- 2014-03-11 CA CA2905327A patent/CA2905327A1/en not_active Abandoned
-
2016
- 2016-05-16 US US15/156,152 patent/US20160324796A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| GB2528801A (en) | 2016-02-03 |
| EP2968166A1 (en) | 2016-01-20 |
| EP2968166A4 (en) | 2016-10-05 |
| KR20150136084A (ko) | 2015-12-04 |
| AU2014248877A1 (en) | 2015-10-01 |
| AU2014248877A8 (en) | 2015-10-29 |
| US20130243864A1 (en) | 2013-09-19 |
| US20160324796A1 (en) | 2016-11-10 |
| WO2014164904A1 (en) | 2014-10-09 |
| KR101902319B1 (ko) | 2018-09-28 |
| BR112015022218A2 (pt) | 2017-07-18 |
| JP2016512527A (ja) | 2016-04-28 |
| SG11201507398XA (en) | 2015-10-29 |
| CN105324108A (zh) | 2016-02-10 |
| RU2015143206A (ru) | 2017-04-18 |
| US10092524B2 (en) | 2018-10-09 |
| HK1216002A1 (zh) | 2016-10-07 |
| GB201516997D0 (en) | 2015-11-11 |
| CA2905327A1 (en) | 2014-10-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PSEA | Patent sealed | ||
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 11 MAR 2019 BY CPA GLOBAL Effective date: 20180201 |
|
| LAPS | Patent lapsed |