NZ609450A - Benzimidazole respiratory syncytial virus inhibitors - Google Patents

Benzimidazole respiratory syncytial virus inhibitors

Info

Publication number
NZ609450A
NZ609450A NZ609450A NZ60945011A NZ609450A NZ 609450 A NZ609450 A NZ 609450A NZ 609450 A NZ609450 A NZ 609450A NZ 60945011 A NZ60945011 A NZ 60945011A NZ 609450 A NZ609450 A NZ 609450A
Authority
NZ
New Zealand
Prior art keywords
respiratory syncytial
syncytial virus
virus inhibitors
benzimidazole
compounds
Prior art date
Application number
NZ609450A
Other languages
English (en)
Inventor
Ludwig Paul Cooymans
Samuël Dominique Demin
Lili Hu
Tim Hugo Maria Jonckers
Pierre Jean-Marie Bernard Raboisson
Abdellah Tahri
Sandrine Marie Helene Vendeville
Original Assignee
Janssen R & D Ireland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43875271&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NZ609450(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Janssen R & D Ireland filed Critical Janssen R & D Ireland
Publication of NZ609450A publication Critical patent/NZ609450A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/26—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NZ609450A 2010-12-16 2011-12-16 Benzimidazole respiratory syncytial virus inhibitors NZ609450A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP10195467 2010-12-16
PCT/EP2011/073008 WO2012080446A1 (en) 2010-12-16 2011-12-16 Benzimidazole respiratory syncytial virus inhibitors

Publications (1)

Publication Number Publication Date
NZ609450A true NZ609450A (en) 2014-10-31

Family

ID=43875271

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ609450A NZ609450A (en) 2010-12-16 2011-12-16 Benzimidazole respiratory syncytial virus inhibitors

Country Status (30)

Country Link
US (1) US8865705B2 (cg-RX-API-DMAC7.html)
EP (1) EP2651903B1 (cg-RX-API-DMAC7.html)
JP (1) JP6005656B2 (cg-RX-API-DMAC7.html)
KR (1) KR101876240B1 (cg-RX-API-DMAC7.html)
CN (2) CN107417683A (cg-RX-API-DMAC7.html)
AR (1) AR085203A1 (cg-RX-API-DMAC7.html)
AU (1) AU2011343255B2 (cg-RX-API-DMAC7.html)
BR (1) BR112013012137A2 (cg-RX-API-DMAC7.html)
CA (1) CA2821999C (cg-RX-API-DMAC7.html)
CL (1) CL2013001713A1 (cg-RX-API-DMAC7.html)
CY (1) CY1117751T1 (cg-RX-API-DMAC7.html)
DK (1) DK2651903T3 (cg-RX-API-DMAC7.html)
EA (1) EA022972B1 (cg-RX-API-DMAC7.html)
ES (1) ES2576180T3 (cg-RX-API-DMAC7.html)
HK (1) HK1247616A1 (cg-RX-API-DMAC7.html)
HR (1) HRP20160650T1 (cg-RX-API-DMAC7.html)
HU (1) HUE029247T2 (cg-RX-API-DMAC7.html)
IL (1) IL225640A (cg-RX-API-DMAC7.html)
MX (1) MX340030B (cg-RX-API-DMAC7.html)
MY (1) MY156641A (cg-RX-API-DMAC7.html)
NZ (1) NZ609450A (cg-RX-API-DMAC7.html)
PH (1) PH12013500796A1 (cg-RX-API-DMAC7.html)
PL (1) PL2651903T3 (cg-RX-API-DMAC7.html)
PT (1) PT2651903E (cg-RX-API-DMAC7.html)
SG (1) SG190766A1 (cg-RX-API-DMAC7.html)
SI (1) SI2651903T1 (cg-RX-API-DMAC7.html)
TW (1) TWI530495B (cg-RX-API-DMAC7.html)
UA (1) UA112298C2 (cg-RX-API-DMAC7.html)
WO (1) WO2012080446A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA201304424B (cg-RX-API-DMAC7.html)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI541241B (zh) 2010-12-16 2016-07-11 健生科學愛爾蘭無限公司 作為呼吸道融合病毒抗病毒劑之咪唑并吡啶類
TWI515187B (zh) * 2010-12-16 2016-01-01 健生科學愛爾蘭無限公司 作為呼吸道融合病毒抗病毒劑之吲哚類
TWI501967B (zh) * 2010-12-16 2015-10-01 Janssen R&D Ireland 作為呼吸道融合病毒抗病毒劑之氮雜吲哚類
TWI527814B (zh) 2010-12-16 2016-04-01 健生科學愛爾蘭無限公司 作為呼吸道融合病毒抗病毒劑之氮雜苯并咪唑類
TWI530495B (zh) 2010-12-16 2016-04-21 健生科學愛爾蘭無限公司 苯并咪唑呼吸道融合病毒抑制劑
EA201590020A1 (ru) * 2012-06-15 2015-03-31 ЯНССЕН Ар ЭНД Ди АЙРЛЭНД Новые производные 1,3-дигидро-2h-бензимидазол-2-она, замещенные бензимидазолами, в качестве противовирусных средств против респираторного синцитиального вируса
KR102092612B1 (ko) 2012-06-15 2020-03-25 얀센 사이언시즈 아일랜드 언리미티드 컴퍼니 호흡기 합포체 바이러스의 항바이러스제로서의 헤테로사이클로 치환된 1,3-디하이드로-2h-벤즈이미다졸-2-온 유도체
WO2014009302A1 (en) * 2012-07-10 2014-01-16 F. Hoffmann-La Roche Ag Novel indazoles for the treatment and prophylaxis of respiratory syncytial virus infection
EP2909195B1 (en) 2012-10-16 2017-06-14 Janssen Sciences Ireland UC Rsv antiviral compounds
EA026546B1 (ru) 2013-01-28 2017-04-28 Янссен Сайенсиз Айрлэнд Юси Хиноксалиноны и дигидрохиноксалиноны как антивирусные средства против респираторно-синцитиального вируса
RU2015148926A (ru) 2013-05-14 2017-06-15 Ф. Хоффманн-Ля Рош Аг Аза-оксо-индолы для лечения и профилактики респираторно-синцитиальной вирусной инфекции
CN105392787B (zh) * 2013-05-14 2017-11-24 豪夫迈·罗氏有限公司 用于治疗和预防呼吸道合胞病毒感染的氮杂‑氧代‑吲哚
EP3033333A1 (en) 2013-08-15 2016-06-22 F. Hoffmann-La Roche AG Novel aza-oxo-indoles for the treatment and prophylaxis of respiratory syncytial virus infection
HK1225716A1 (zh) 2013-08-21 2017-09-15 Alios Biopharma, Inc. 抗病毒化合物
WO2015065336A1 (en) * 2013-10-29 2015-05-07 Medivir Ab Respiratory syncytial virus inhibitors
TWI671299B (zh) 2014-04-14 2019-09-11 愛爾蘭商健生科學愛爾蘭無限公司 作為ｒｓｖ抗病毒化合物之螺脲化合物
CA2957017A1 (en) * 2014-08-05 2016-02-11 Alios Biopharma, Inc. Combination therapy for treating a paramyxovirus
MA41614A (fr) 2015-02-25 2018-01-02 Alios Biopharma Inc Composés antiviraux
MX381798B (es) 2015-07-22 2025-03-13 Enanta Pharm Inc Derivados de benzodiazepina como inhibidores de rsv
EP3402799B1 (en) 2016-01-15 2022-05-04 Enanta Pharmaceuticals, Inc. Heterocyclic compounds as rsv inhibitors
CN110809472B (zh) 2017-02-16 2023-05-23 英安塔制药有限公司 用于制备苯二氮䓬衍生物的方法
WO2019006295A1 (en) 2017-06-30 2019-01-03 Enanta Pharmaceuticals, Inc. HETEROCYCLIC COMPOUNDS AS RSV INHIBITORS
US10881666B2 (en) 2017-09-29 2021-01-05 Enanta Pharmaceuticals, Inc. Combination pharmaceutical agents as RSV inhibitors
JP7228588B2 (ja) 2017-11-13 2023-02-24 エナンタ ファーマシューティカルズ インコーポレイテッド ベンゾジアゼピン－２－オンおよびベンゾアゼピン－２－オン誘導体の分割方法
BR112021018335A2 (pt) 2019-03-18 2021-11-23 Enanta Pharm Inc Derivados de benzodiazepina como inibidores de rsv
US11505558B1 (en) 2019-10-04 2022-11-22 Enanta Pharmaceuticals, Inc. Antiviral heterocyclic compounds
TWI864048B (zh) 2019-10-04 2024-12-01 美商安塔製藥公司 抗病毒雜環化合物、其醫藥組成物及其用途
UY39032A (es) 2020-01-24 2021-07-30 Enanta Pharm Inc Compuestos heterocíclicos como agentes antivirales
US12145933B2 (en) 2020-06-11 2024-11-19 Janssen Sciences Ireland Unlimited Company Hemi (L)-tartrate forms of 3-({5-chloro-1-[3-(methylsulfonyl)propyl]-1H-indol-2-yl}methyl)-1-(2,2,2-trifluoroethy)-1,3-dihydro-2H-imidazo[4,5-C]pyridin-2-one and pharmaceutical compositions comprising the same
WO2022010882A1 (en) 2020-07-07 2022-01-13 Enanta Pharmaceuticals, Inc, Dihydroquinoxaline and dihydropyridopyrazine derivatives as rsv inhibitors
WO2022086840A1 (en) 2020-10-19 2022-04-28 Enanta Pharmaceuticals, Inc. Heterocyclic compounds as anti-viral agents
WO2022182861A1 (en) 2021-02-26 2022-09-01 Enanta Pharmaceuticals, Inc. Antiviral heterocyclic compounds
AR129003A1 (es) 2022-04-07 2024-07-03 Enanta Pharm Inc Compuestos heterocíclicos antivirales
WO2023211997A1 (en) 2022-04-27 2023-11-02 Enanta Pharmaceuticals, Inc. Antiviral compounds
WO2024174953A1 (zh) * 2023-02-21 2024-08-29 苏州隆博泰药业有限公司 苯并咪唑类衍生物及其医药用途

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002514162A (ja) 1996-07-08 2002-05-14 デュポン ファーマシューティカルズ カンパニー Ｘａ因子阻害薬およびトロンビン阻害薬としてのアミジノインドール類、アミジノアゾール類、およびそれらの類似体
AU1099000A (en) 1998-10-05 2000-04-26 Axys Pharmaceuticals, Inc. Novel compounds and compositions for treating hepatitis c infections
TR200103804T2 (tr) 1999-06-28 2002-05-21 Janssen Pharmaceutica N.V. Solunum sistemi sinsitiyal virüsünün replikasyonunu inhibe edici maddeler
EE04591B1 (et) 1999-06-28 2006-02-15 Janssen Pharmaceutica N.V. Respiratoorse süntsütiaalviiruse replikatsiooni inhibiitorid, nende valmistamismeetod, kasutamine ja vaheühendid, farmatseutiline kompositsioon ja selle valmistamismeetod ning produkt
US6534535B1 (en) 1999-08-12 2003-03-18 Millennium Pharmaceuticals, Inc. Inhibitors of factor Xa
US6489338B2 (en) * 2000-06-13 2002-12-03 Bristol-Myers Squibb Company Imidazopyridine and imidazopyrimidine antiviral agents
US6506738B1 (en) 2000-09-27 2003-01-14 Bristol-Myers Squibb Company Benzimidazolone antiviral agents
US6919331B2 (en) * 2001-12-10 2005-07-19 Bristol-Myers Squibb Company Substituted 2-methyl-benzimidazole respiratory syncytial virus antiviral agents
WO2004043913A2 (en) 2002-11-08 2004-05-27 Trimeris, Inc. Hetero-substituted benzimidazole compounds and antiviral uses thereof
TWI515187B (zh) 2010-12-16 2016-01-01 健生科學愛爾蘭無限公司 作為呼吸道融合病毒抗病毒劑之吲哚類
TWI530495B (zh) 2010-12-16 2016-04-21 健生科學愛爾蘭無限公司 苯并咪唑呼吸道融合病毒抑制劑
TWI541241B (zh) 2010-12-16 2016-07-11 健生科學愛爾蘭無限公司 作為呼吸道融合病毒抗病毒劑之咪唑并吡啶類
TWI527814B (zh) 2010-12-16 2016-04-01 健生科學愛爾蘭無限公司 作為呼吸道融合病毒抗病毒劑之氮雜苯并咪唑類
TWI501967B (zh) 2010-12-16 2015-10-01 Janssen R&D Ireland 作為呼吸道融合病毒抗病毒劑之氮雜吲哚類

Also Published As

Publication number Publication date
AU2011343255B2 (en) 2014-12-11
TWI530495B (zh) 2016-04-21
EA201390888A1 (ru) 2013-12-30
SI2651903T1 (sl) 2016-07-29
CA2821999C (en) 2019-02-26
EP2651903B1 (en) 2016-03-23
HK1247616A1 (zh) 2018-09-28
CN103313974A (zh) 2013-09-18
PT2651903E (pt) 2016-06-17
PL2651903T3 (pl) 2016-10-31
BR112013012137A2 (pt) 2016-08-16
PH12013500796A1 (en) 2013-06-24
UA112298C2 (uk) 2016-08-25
SG190766A1 (en) 2013-07-31
CA2821999A1 (en) 2012-06-21
EP2651903A1 (en) 2013-10-23
CN107417683A (zh) 2017-12-01
HRP20160650T1 (hr) 2016-07-15
ES2576180T3 (es) 2016-07-06
AU2011343255A1 (en) 2013-05-02
MX340030B (es) 2016-06-21
WO2012080446A1 (en) 2012-06-21
AR085203A1 (es) 2013-09-18
US20130267508A1 (en) 2013-10-10
JP2013545785A (ja) 2013-12-26
JP6005656B2 (ja) 2016-10-12
US8865705B2 (en) 2014-10-21
IL225640A (en) 2015-02-26
CL2013001713A1 (es) 2013-10-11
KR20140025321A (ko) 2014-03-04
ZA201304424B (en) 2014-12-23
MX2013006886A (es) 2013-07-05
DK2651903T3 (da) 2016-06-27
TW201305142A (zh) 2013-02-01
CY1117751T1 (el) 2017-05-17
HUE029247T2 (en) 2017-02-28
IL225640A0 (en) 2013-06-27
KR101876240B1 (ko) 2018-08-02
EA022972B1 (ru) 2016-03-31
MY156641A (en) 2016-03-15

Similar Documents

Publication Publication Date Title
NZ609450A (en) Benzimidazole respiratory syncytial virus inhibitors
SI2419428T1 (sl) Imidazo (1,2-a) piridin derivati kot FGFR kinaza inhibitorji za uporabo v terapiji
BR112013014854A8 (pt) compostos de n-(1h-indazol-4-il)imidazo [1,2-a] piridina-3-carboxamida substituídos como inibidores de tirosina quinase de receptor tipo iii
BR112014030400A2 (pt) formas sólidas de um composto antiviral
NZ626394A (en) Substituted annulated pyrimidines and triazines, and use thereof
CR20110420A (es) Composiciones del acido propano-1-sulfonico {3-[5-(4-cloro-fenil) -1h-pirrolo [2,3-b] piridina-3-carbonil] -2,4-difluoro-fenil}-amida y el uso de las mismas
NZ609487A (en) Indoles as respiratory syncytial virus antiviral agents
SMT201300110B (it) Processi intermedi per la preparazione di analoghidi 1'-cianocarbonucleoside
CU24155B1 (es) DERIVADOS DE 1-(5,6-DIHIDROIMIDAZO(1,2-a)PIRAZIN-7(8H)-IL )ETANONA
MY152062A (en) Indole derivatives as crth2 receptor antagonists
EP2480079A4 (en) PYRIDO- (3,4-B-) INDOLE AND USE METHOD THEREFOR
NZ596488A (en) 1, 3-disubstituted imidazolidin-2-one derivatives as inhibitors of cyp 17
EP2580214A4 (en) 8- (SULFONYLARYL) PYRIDO [2,3-D] PYRIMIDIN-7 (8H) -ONES FOR THE TREATMENT OF CNS DISORDERS
MX2013001805A (es) Derivados de 2-(arilamino)-3h-imidazo [4,5-b] piridina-6-carboxamida y su uso como inhibidores de mpges-1.
SG10201500639TA (en) Processes for the preparation of (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid and salts thereof
BRPI0809998A2 (pt) Composto de imidazo[1,2-a] piridina como inibidores do receptor tirosina cinase
EA201071234A1 (ru) Производные изохинолинона в качестве nk3 антагонистов
IL216452A0 (en) 1H-IMIDAZO[4,5-c]QUINOLINONE DERIVATIVES
WO2010031184A8 (en) Azaindole derivatives as crth2 receptor antagonists
WO2011156786A8 (en) 6-(ethynyl)pyrido[2,3-d]pyrimidin-7(8h)-ones for the treatment of cns disorders
MX2011012993A (es) Bencimidazoles, benzotiazoles y benzoxazoles, sustituidos.
WO2011101069A3 (en) 1, 8 -naphthyridines as kinase inhibitors
IL213242A0 (en) Imidazopyridine derivatives which inhibit the secretion of gastric acid
IL219861A0 (en) Process for preparing methyl {4,6-diamino-2-[1-(2-fluorobenzyl)-1h-pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-5-yl}carbamate and its purification for use as pharmaceutically active compound
PH12014500079A1 (en) 6-substituted phenoxychroman carboxylic acid derivatives

Legal Events

Date Code Title Description
PSEA Patent sealed
ASS Change of ownership

Owner name: JANSSEN SCIENCES IRELAND UC, IE

Effective date: 20150723

RENW Renewal (renewal fees accepted)

Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 16 DEC 2016 BY CPA GLOBAL

Effective date: 20151030

RENW Renewal (renewal fees accepted)

Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 16 DEC 2017 BY CPA GLOBAL

Effective date: 20161108

RENW Renewal (renewal fees accepted)

Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 16 DEC 2018 BY CPA GLOBAL

Effective date: 20171102

RENW Renewal (renewal fees accepted)

Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 16 DEC 2019 BY CPA GLOBAL

Effective date: 20181102

RENW Renewal (renewal fees accepted)

Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 16 DEC 2020 BY CPA GLOBAL

Effective date: 20191031

RENW Renewal (renewal fees accepted)

Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 16 DEC 2021 BY CPA GLOBAL

Effective date: 20201030

RENW Renewal (renewal fees accepted)

Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 16 DEC 2022 BY CPA GLOBAL

Effective date: 20211104

LAPS Patent lapsed