NZ595982A - Method and apparatus for isolating a target bioentity from a biological sample - Google Patents

Method and apparatus for isolating a target bioentity from a biological sample

Info

Publication number
NZ595982A
NZ595982A NZ595982A NZ59598210A NZ595982A NZ 595982 A NZ595982 A NZ 595982A NZ 595982 A NZ595982 A NZ 595982A NZ 59598210 A NZ59598210 A NZ 59598210A NZ 595982 A NZ595982 A NZ 595982A
Authority
NZ
New Zealand
Prior art keywords
flow path
fluid flow
biological sample
magnetic field
module
Prior art date
Application number
NZ595982A
Other languages
English (en)
Inventor
Howard Milne Chandler
Michael Bruce Chandler
Original Assignee
Clinical Genomics Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Clinical Genomics Pty Ltd filed Critical Clinical Genomics Pty Ltd
Publication of NZ595982A publication Critical patent/NZ595982A/xx

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00—Magnetic separation
    • B03C1/02—Magnetic separation acting directly on the substance being separated
    • B03C1/28—Magnetic plugs and dipsticks
    • B03C1/288—Magnetic plugs and dipsticks disposed at the outer circumference of a recipient
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00—Magnetic separation
    • B03C1/005—Pretreatment specially adapted for magnetic separation
    • B03C1/01—Pretreatment specially adapted for magnetic separation by addition of magnetic adjuvants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C2201/00—Details of magnetic or electrostatic separation
    • B03C2201/18—Magnetic separation whereby the particles are suspended in a liquid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C2201/00—Details of magnetic or electrostatic separation
    • B03C2201/26—Details of magnetic or electrostatic separation for use in medical or biological applications

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
NZ595982A 2009-04-22 2010-04-22 Method and apparatus for isolating a target bioentity from a biological sample NZ595982A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US17153209P 2009-04-22 2009-04-22
US18266109P 2009-05-29 2009-05-29
US28528609P 2009-12-10 2009-12-10
PCT/AU2010/000459 WO2010121315A1 (en) 2009-04-22 2010-04-22 Method and apparatus for isolating a target bioentity from a biological sample

Publications (1)

Publication Number Publication Date
NZ595982A true NZ595982A (en) 2013-10-25

Family

ID=43010599

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ595982A NZ595982A (en) 2009-04-22 2010-04-22 Method and apparatus for isolating a target bioentity from a biological sample

Country Status (9)

Country Link
US (1) US20120115167A1 (https=)
EP (1) EP2421654A1 (https=)
JP (1) JP2012524885A (https=)
CN (1) CN102458665A (https=)
AU (1) AU2010239154A1 (https=)
IL (1) IL215807A0 (https=)
NZ (1) NZ595982A (https=)
RU (1) RU2011147219A (https=)
WO (1) WO2010121315A1 (https=)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2642313T3 (es) * 2010-11-09 2017-11-16 Arcedi Biotech Aps Enriquecimiento e identificación de células fetales en sangre materna y ligandos para tal uso
WO2012113028A1 (en) * 2011-02-23 2012-08-30 Clinical Genomics Pty. Ltd. Isolation of a target bioentity from a biological sample
WO2012172503A1 (en) * 2011-06-15 2012-12-20 Koninklijke Philips Electronics N.V. Processing of biological sample components
WO2013003898A1 (en) * 2011-07-07 2013-01-10 Clinical Genomics Pty. Ltd Method for detection of cancer in a patient
DE102011088741B4 (de) 2011-12-15 2013-07-25 Institut für Bioprozess- und Analysenmesstechnik e.V. Verfahren und Anordnung zum Markieren und Separieren von Zellen aus einer Zellsuspension
US11648561B2 (en) 2012-02-13 2023-05-16 Neumodx Molecular, Inc. System and method for processing and detecting nucleic acids
US9637775B2 (en) 2012-02-13 2017-05-02 Neumodx Molecular, Inc. System and method for processing biological samples
US9604213B2 (en) 2012-02-13 2017-03-28 Neumodx Molecular, Inc. System and method for processing and detecting nucleic acids
US9738887B2 (en) 2012-02-13 2017-08-22 Neumodx Molecular, Inc. Microfluidic cartridge for processing and detecting nucleic acids
US20140024136A1 (en) * 2012-07-19 2014-01-23 Derek L. Chappell Magnetic particle separator
CN102911864B (zh) * 2012-10-15 2014-08-06 宁波美晶医疗技术有限公司 一种血液中稀有细胞的分离仪
WO2014066376A1 (en) 2012-10-25 2014-05-01 Neumodx Molecular, Inc. Method and materials for isolation of nucleic acid materials
CN103131693B (zh) * 2013-02-25 2014-12-24 宁波美晶医疗技术有限公司 一种血液中稀有细胞的分离方法
CN103131634B (zh) * 2013-02-25 2014-09-03 宁波美晶医疗技术有限公司 一种基于微磁场的免疫肿瘤细胞筛选系统
EP3058316B1 (en) * 2013-10-18 2019-03-13 The General Hospital Corporation Microfluidic sorting using high gradient magnetic fields
CN103940997B (zh) * 2014-03-21 2017-01-04 上海柏慧康生物科技有限公司 一种乳腺癌循环肿瘤细胞检测系统及试剂盒
GB2549624B (en) * 2014-11-28 2021-07-21 Valetude Primus Healthcare Pvt Ltd Magnetic capturing of rare cells
EP3061529A1 (en) * 2015-02-24 2016-08-31 AdnaGen GmbH Apparatus and method for the analysis, isolation and/or enrichment of target structures in a fluid sample
WO2016183032A1 (en) 2015-05-08 2016-11-17 Biomagnetic Solutions Llc Apparatus and method for immunomagnetic cell separation
CN115655825A (zh) * 2015-09-18 2023-01-31 紫荆实验室股份有限公司 利用表面附着结构的流动池，以及相关的系统和方法
WO2017053630A1 (en) * 2015-09-22 2017-03-30 Purdue Research Foundation Centrifuge-free isolation and detection of rare cells
JP7429343B2 (ja) 2018-01-05 2024-02-08 パス イーエックス，インク． 流体からの疾患材料の捕捉および除去のためのデバイス
KR102816402B1 (ko) * 2018-09-28 2025-06-04 옥테인 바이오테크 인코포레이티드 자기 분리
WO2020086761A1 (en) * 2018-10-24 2020-04-30 Path Ex, Inc. Method for the capture and isolation of disease material from flowing matter
SG11202113242QA (en) 2019-06-07 2021-12-30 Arcedi Biotech Aps Isolation of fetal cells using facs
BR112022002969A2 (pt) * 2019-08-30 2022-05-17 Flodesign Sonics Inc Seleção de células de afinidade acústica para múltiplos receptores alvo
CN113125707A (zh) * 2020-01-10 2021-07-16 陈琪 一种分离磁微粒的方法、装置及设备
EP4616195A1 (en) * 2022-11-08 2025-09-17 Zhong Li Methods for detecting target compounds and uses thereof
CN120838569B (zh) * 2025-07-30 2026-01-06 上海迪化科技股份有限公司 一种磁珠连续分离工艺及装置
CN120644311B (zh) * 2025-07-30 2026-02-06 上海迪化科技股份有限公司 一种磁珠连续分离系统和控制方法

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1575805A (en) * 1976-03-12 1980-10-01 Technicon Instr Automatic diagnostic apparatus
EP0398880A4 (en) * 1988-01-04 1990-12-27 E.I. Du Pont De Nemours And Company Multiple stage affinity process for isolation of specific cells from a cell mixture
US5795470A (en) * 1991-03-25 1998-08-18 Immunivest Corporation Magnetic separation apparatus
AU4927496A (en) * 1995-02-21 1996-09-11 Iqbal W. Siddiqi Apparatus and method for mixing and separation employing magnetic particles
US5705059A (en) * 1995-02-27 1998-01-06 Miltenyi; Stefan Magnetic separation apparatus
FR2748569B1 (fr) * 1996-05-07 1998-08-07 Biocom Sa Procede et installation de separation de particules magnetiques dans un fluide pour l'analyse biologique, et application dudit procede
US20030095897A1 (en) * 2001-08-31 2003-05-22 Grate Jay W. Flow-controlled magnetic particle manipulation
CN1230531C (zh) * 2002-12-09 2005-12-07 清华大学 从样品中分离细胞粒子的方法
US7553625B2 (en) * 2003-12-22 2009-06-30 John Wayne Cancer Institute Method and apparatus for in vivo collection of circulating biological components
JP2006010529A (ja) * 2004-06-25 2006-01-12 Canon Inc 磁性粒子分離装置および分離方法
JP2006051850A (ja) * 2004-08-10 2006-02-23 Matsushita Electric Ind Co Ltd 運転支援装置及び運転支援方法
EP1886138A4 (en) * 2005-05-11 2009-04-15 Genetic Technologies Ltd METHODS FOR ENRICHING FETAL CELLS
JP2007010500A (ja) * 2005-06-30 2007-01-18 Canon Inc サンプル検出装置とそれを含む検体分析装置
WO2007092713A2 (en) * 2006-02-02 2007-08-16 Trustees Of The University Of Pennsylvania Microfluidic system and method for analysis of gene expression in cell-containing samples and detection of disease
WO2007106013A1 (en) * 2006-03-13 2007-09-20 Gyros Patent Ab Enhanced magnetic particle steering
CN100546724C (zh) * 2006-06-30 2009-10-07 上海师范大学 磁性分离柱及其在生物样品分离中的应用
WO2009026566A1 (en) * 2007-08-23 2009-02-26 Cynvenio Biosystems, Llc Trapping magnetic sorting system for target species
WO2009117611A2 (en) * 2008-03-19 2009-09-24 Cynvenio Biosystems, Llc Trapping magnetic cell sorting system
US20110137018A1 (en) * 2008-04-16 2011-06-09 Cynvenio Biosystems, Inc. Magnetic separation system with pre and post processing modules
US8377669B2 (en) * 2009-11-17 2013-02-19 Abbott Point Of Care Inc. Reducing leukocyte interference in non-competitive immunoassays

Also Published As

Publication number Publication date
WO2010121315A1 (en) 2010-10-28
RU2011147219A (ru) 2013-05-27
CN102458665A (zh) 2012-05-16
US20120115167A1 (en) 2012-05-10
IL215807A0 (en) 2012-01-31
EP2421654A1 (en) 2012-02-29
JP2012524885A (ja) 2012-10-18
AU2010239154A1 (en) 2011-11-10

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Legal Events

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PSEA Patent sealed
RENW Renewal (renewal fees accepted)

Free format text: PATENT RENEWED FOR 3 YEARS UNTIL 22 APR 2017 BY DAVIES COLLISON CAVE

Effective date: 20140129

LAPS Patent lapsed