AU2010239154A1 - Method and apparatus for isolating a target bioentity from a biological sample - Google Patents

Method and apparatus for isolating a target bioentity from a biological sample Download PDF

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Publication number
AU2010239154A1
AU2010239154A1 AU2010239154A AU2010239154A AU2010239154A1 AU 2010239154 A1 AU2010239154 A1 AU 2010239154A1 AU 2010239154 A AU2010239154 A AU 2010239154A AU 2010239154 A AU2010239154 A AU 2010239154A AU 2010239154 A1 AU2010239154 A1 AU 2010239154A1
Authority
AU
Australia
Prior art keywords
flow path
fluid flow
magnetic
module
biological sample
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2010239154A
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English (en)
Inventor
Howard Milne Chandler
Michael Bruce Chandler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Clinical Genomics Pty Ltd
Original Assignee
Clinical Genomics Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Clinical Genomics Pty Ltd filed Critical Clinical Genomics Pty Ltd
Publication of AU2010239154A1 publication Critical patent/AU2010239154A1/en
Abandoned legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00—Magnetic separation
    • B03C1/02—Magnetic separation acting directly on the substance being separated
    • B03C1/28—Magnetic plugs and dipsticks
    • B03C1/288—Magnetic plugs and dipsticks disposed at the outer circumference of a recipient
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00—Magnetic separation
    • B03C1/005—Pretreatment specially adapted for magnetic separation
    • B03C1/01—Pretreatment specially adapted for magnetic separation by addition of magnetic adjuvants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C2201/00—Details of magnetic or electrostatic separation
    • B03C2201/18—Magnetic separation whereby the particles are suspended in a liquid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C2201/00—Details of magnetic or electrostatic separation
    • B03C2201/26—Details of magnetic or electrostatic separation for use in medical or biological applications

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AU2010239154A 2009-04-22 2010-04-22 Method and apparatus for isolating a target bioentity from a biological sample Abandoned AU2010239154A1 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US17153209P 2009-04-22 2009-04-22
US61/171,532 2009-04-22
US18266109P 2009-05-29 2009-05-29
US61/182,661 2009-05-29
US28528609P 2009-12-10 2009-12-10
US61/285,286 2009-12-10
PCT/AU2010/000459 WO2010121315A1 (en) 2009-04-22 2010-04-22 Method and apparatus for isolating a target bioentity from a biological sample

Publications (1)

Publication Number Publication Date
AU2010239154A1 true AU2010239154A1 (en) 2011-11-10

Family

ID=43010599

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2010239154A Abandoned AU2010239154A1 (en) 2009-04-22 2010-04-22 Method and apparatus for isolating a target bioentity from a biological sample

Country Status (9)

Country Link
US (1) US20120115167A1 (https=)
EP (1) EP2421654A1 (https=)
JP (1) JP2012524885A (https=)
CN (1) CN102458665A (https=)
AU (1) AU2010239154A1 (https=)
IL (1) IL215807A0 (https=)
NZ (1) NZ595982A (https=)
RU (1) RU2011147219A (https=)
WO (1) WO2010121315A1 (https=)

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WO2012113028A1 (en) * 2011-02-23 2012-08-30 Clinical Genomics Pty. Ltd. Isolation of a target bioentity from a biological sample
WO2012172503A1 (en) * 2011-06-15 2012-12-20 Koninklijke Philips Electronics N.V. Processing of biological sample components
WO2013003898A1 (en) * 2011-07-07 2013-01-10 Clinical Genomics Pty. Ltd Method for detection of cancer in a patient
DE102011088741B4 (de) 2011-12-15 2013-07-25 Institut für Bioprozess- und Analysenmesstechnik e.V. Verfahren und Anordnung zum Markieren und Separieren von Zellen aus einer Zellsuspension
US11648561B2 (en) 2012-02-13 2023-05-16 Neumodx Molecular, Inc. System and method for processing and detecting nucleic acids
US9637775B2 (en) 2012-02-13 2017-05-02 Neumodx Molecular, Inc. System and method for processing biological samples
US9604213B2 (en) 2012-02-13 2017-03-28 Neumodx Molecular, Inc. System and method for processing and detecting nucleic acids
US9738887B2 (en) 2012-02-13 2017-08-22 Neumodx Molecular, Inc. Microfluidic cartridge for processing and detecting nucleic acids
US20140024136A1 (en) * 2012-07-19 2014-01-23 Derek L. Chappell Magnetic particle separator
CN102911864B (zh) * 2012-10-15 2014-08-06 宁波美晶医疗技术有限公司 一种血液中稀有细胞的分离仪
WO2014066376A1 (en) 2012-10-25 2014-05-01 Neumodx Molecular, Inc. Method and materials for isolation of nucleic acid materials
CN103131693B (zh) * 2013-02-25 2014-12-24 宁波美晶医疗技术有限公司 一种血液中稀有细胞的分离方法
CN103131634B (zh) * 2013-02-25 2014-09-03 宁波美晶医疗技术有限公司 一种基于微磁场的免疫肿瘤细胞筛选系统
EP3058316B1 (en) * 2013-10-18 2019-03-13 The General Hospital Corporation Microfluidic sorting using high gradient magnetic fields
CN103940997B (zh) * 2014-03-21 2017-01-04 上海柏慧康生物科技有限公司 一种乳腺癌循环肿瘤细胞检测系统及试剂盒
GB2549624B (en) * 2014-11-28 2021-07-21 Valetude Primus Healthcare Pvt Ltd Magnetic capturing of rare cells
EP3061529A1 (en) * 2015-02-24 2016-08-31 AdnaGen GmbH Apparatus and method for the analysis, isolation and/or enrichment of target structures in a fluid sample
WO2016183032A1 (en) 2015-05-08 2016-11-17 Biomagnetic Solutions Llc Apparatus and method for immunomagnetic cell separation
CN115655825A (zh) * 2015-09-18 2023-01-31 紫荆实验室股份有限公司 利用表面附着结构的流动池，以及相关的系统和方法
WO2017053630A1 (en) * 2015-09-22 2017-03-30 Purdue Research Foundation Centrifuge-free isolation and detection of rare cells
JP7429343B2 (ja) 2018-01-05 2024-02-08 パス イーエックス，インク． 流体からの疾患材料の捕捉および除去のためのデバイス
KR102816402B1 (ko) * 2018-09-28 2025-06-04 옥테인 바이오테크 인코포레이티드 자기 분리
WO2020086761A1 (en) * 2018-10-24 2020-04-30 Path Ex, Inc. Method for the capture and isolation of disease material from flowing matter
SG11202113242QA (en) 2019-06-07 2021-12-30 Arcedi Biotech Aps Isolation of fetal cells using facs
BR112022002969A2 (pt) * 2019-08-30 2022-05-17 Flodesign Sonics Inc Seleção de células de afinidade acústica para múltiplos receptores alvo
CN113125707A (zh) * 2020-01-10 2021-07-16 陈琪 一种分离磁微粒的方法、装置及设备
EP4616195A1 (en) * 2022-11-08 2025-09-17 Zhong Li Methods for detecting target compounds and uses thereof
CN120838569B (zh) * 2025-07-30 2026-01-06 上海迪化科技股份有限公司 一种磁珠连续分离工艺及装置
CN120644311B (zh) * 2025-07-30 2026-02-06 上海迪化科技股份有限公司 一种磁珠连续分离系统和控制方法

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Also Published As

Publication number Publication date
WO2010121315A1 (en) 2010-10-28
RU2011147219A (ru) 2013-05-27
CN102458665A (zh) 2012-05-16
US20120115167A1 (en) 2012-05-10
IL215807A0 (en) 2012-01-31
NZ595982A (en) 2013-10-25
EP2421654A1 (en) 2012-02-29
JP2012524885A (ja) 2012-10-18

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MK1 Application lapsed section 142(2)(a) - no request for examination in relevant period