NZ550199A - Treatment of inflammation, abeta-induced cell toxicity, neuronal cell death or neuronal cell loss in subjects suffering from alzheimer's disease - Google Patents

Treatment of inflammation, abeta-induced cell toxicity, neuronal cell death or neuronal cell loss in subjects suffering from alzheimer's disease

Info

Publication number
NZ550199A
NZ550199A NZ550199A NZ55019999A NZ550199A NZ 550199 A NZ550199 A NZ 550199A NZ 550199 A NZ550199 A NZ 550199A NZ 55019999 A NZ55019999 A NZ 55019999A NZ 550199 A NZ550199 A NZ 550199A
Authority
NZ
New Zealand
Prior art keywords
use according
acid
medicament
anionic
disease
Prior art date
Application number
NZ550199A
Other languages
English (en)
Original Assignee
Bellus Health Int Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bellus Health Int Ltd filed Critical Bellus Health Int Ltd
Publication of NZ550199A publication Critical patent/NZ550199A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
NZ550199A 1998-02-11 1999-02-11 Treatment of inflammation, abeta-induced cell toxicity, neuronal cell death or neuronal cell loss in subjects suffering from alzheimer's disease NZ550199A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7429598P 1998-02-11 1998-02-11
US24839699A 1999-02-10 1999-02-10

Publications (1)

Publication Number Publication Date
NZ550199A true NZ550199A (en) 2008-07-31

Family

ID=26755484

Family Applications (2)

Application Number Title Priority Date Filing Date
NZ550199A NZ550199A (en) 1998-02-11 1999-02-11 Treatment of inflammation, abeta-induced cell toxicity, neuronal cell death or neuronal cell loss in subjects suffering from alzheimer's disease
NZ568553A NZ568553A (en) 1998-02-11 1999-02-11 Treatment of inflammation, AB-induced cell toxicity, neuronal cell death or neuronal loss in subjects suffering from AlzheimerÆs disease

Family Applications After (1)

Application Number Title Priority Date Filing Date
NZ568553A NZ568553A (en) 1998-02-11 1999-02-11 Treatment of inflammation, AB-induced cell toxicity, neuronal cell death or neuronal loss in subjects suffering from AlzheimerÆs disease

Country Status (12)

Country Link
EP (1) EP1054664B1 (enExample)
JP (1) JP4574845B2 (enExample)
AU (1) AU2437899A (enExample)
CA (2) CA2632106A1 (enExample)
CY (1) CY1113205T1 (enExample)
DK (1) DK1054664T3 (enExample)
ES (1) ES2392391T3 (enExample)
IL (1) IL137751A0 (enExample)
MX (2) MXPA00007815A (enExample)
NZ (2) NZ550199A (enExample)
PT (1) PT1054664E (enExample)
WO (1) WO1999040909A1 (enExample)

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US5605938A (en) 1991-05-31 1997-02-25 Gliatech, Inc. Methods and compositions for inhibition of cell invasion and fibrosis using dextran sulfate
AU3726299A (en) * 1998-05-15 1999-12-06 Neurochem, Inc. Use of amyloid inhibitors for modulating neuronal cell death
US6310073B1 (en) 1998-07-28 2001-10-30 Queen's University At Kingston Methods and compositions to treat glycosaminoglycan-associated molecular interactions
KR100822525B1 (ko) * 1999-04-28 2008-04-16 뉴로겜 인터내셔널 리미티드 아밀로이드증 치료용 조성물 및 방법
WO2001003680A2 (en) * 1999-07-09 2001-01-18 Isis Innovation Limited Compounds for inhibiting diseases and preparing cells for transplantation
US6670399B2 (en) 1999-12-23 2003-12-30 Neurochem (International) Limited Compounds and methods for modulating cerebral amyloid angiopathy
US7105336B2 (en) * 2002-10-07 2006-09-12 Biogaia Ab Selection and use of lactic acid bacteria for reducing inflammation caused by Helicobacter
JP2006512417A (ja) * 2002-12-24 2006-04-13 ニューロケム (インターナショナル) リミテッド β−アミロイド関連疾患の治療のための治療用製剤
CN1753662A (zh) * 2002-12-24 2006-03-29 神经化学(国际)有限公司 用于治疗β-淀粉状蛋白相关疾病的治疗制剂
DE10303974A1 (de) 2003-01-31 2004-08-05 Abbott Gmbh & Co. Kg Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung
US7253306B2 (en) 2003-06-23 2007-08-07 Neurochem (International) Limited Pharmaceutical drug candidates and methods for preparation thereof
US20050142191A1 (en) * 2003-06-23 2005-06-30 Neurochem (International) Limited Pharmaceutical formulations of amyloid inhibiting compounds
US7414076B2 (en) 2003-06-23 2008-08-19 Neurochem (International) Limited Methods and compositions for treating amyloid-related diseases
US7244764B2 (en) 2003-06-23 2007-07-17 Neurochem (International) Limited Methods and compositions for treating amyloid-related diseases
MXPA05013607A (es) * 2003-06-23 2006-04-06 Neurochem Int Ltd Candidatos de farmaco farmaceuticos mejorados y metodos para preparar los mismos.
CA2900876A1 (en) 2004-12-22 2006-08-17 Bhi Limited Partnership Methods and compositions for treating amyloid-related diseases
TW200716088A (en) * 2005-04-15 2007-05-01 Neurochem Int Ltd Formulations and methods for treating amyloidosis
SG10201706600VA (en) 2005-11-30 2017-09-28 Abbvie Inc Monoclonal antibodies and uses thereof
KR20080090408A (ko) 2005-11-30 2008-10-08 아보트 러보러터리즈 항-Aβ 글로불로머 항체, 이의 항원-결합 잔기, 상응하는하이브리도마, 핵산, 벡터, 숙주 세포, 당해 항체의 제조방법, 당해 항체를 포함하는 조성물, 당해 항체의 용도 및당해 항체의 사용 방법
CA2634871A1 (en) 2005-12-22 2007-11-08 Neurochem (International) Limited Treatment of renal disorders, diabetic nephopathy and dyslipidemias
PT2089417E (pt) 2006-10-12 2015-04-14 Bhi Ltd Partnership Métodos, compostos, composições e veículos para administrar o ácido 3-amino-1-propanossulfónico
US8455626B2 (en) 2006-11-30 2013-06-04 Abbott Laboratories Aβ conformer selective anti-aβ globulomer monoclonal antibodies
WO2008104386A2 (en) 2007-02-27 2008-09-04 Abbott Gmbh & Co. Kg Method for the treatment of amyloidoses
US8048420B2 (en) 2007-06-12 2011-11-01 Ac Immune S.A. Monoclonal antibody
US8613923B2 (en) 2007-06-12 2013-12-24 Ac Immune S.A. Monoclonal antibody
CA2701793C (en) 2007-10-05 2017-04-25 Genentech, Inc. Use of anti-amyloid beta antibody in ocular diseases
WO2010094734A2 (en) * 2009-02-19 2010-08-26 Biofocus Dpi B.V. Methods for identifying and compounds useful for the diagnosis and treatment of diseases involving inflammation
MY174012A (en) * 2009-09-17 2020-03-03 Bespoke Bioscience Llc Role of n-2-hydroxy-ethyl-piperazine-n'-2-ethane sulfonic acid (hepes) in pain control and reversal of demyelinization injury
EP2558494B1 (en) 2010-04-15 2018-05-23 AbbVie Inc. Amyloid-beta binding proteins
CN103179981B (zh) 2010-07-30 2017-02-08 Ac免疫有限公司 安全和功能性的人源化抗β‑淀粉样蛋白抗体
US9062101B2 (en) 2010-08-14 2015-06-23 AbbVie Deutschland GmbH & Co. KG Amyloid-beta binding proteins
WO2016163886A2 (en) * 2015-04-10 2016-10-13 Clues2Cure International B.V. Administration of taurine or an analog thereof for the treatment of nerve cell damage
CN109381452A (zh) * 2017-08-11 2019-02-26 江西青峰药业有限公司 乙基硫酸类化合物的应用及其制备方法
CN109381453A (zh) * 2017-08-14 2019-02-26 江西青峰药业有限公司 乙基硫酸钾在制备用于预防或治疗炎症性疾病药物中的应用
CN109394746A (zh) * 2017-08-15 2019-03-01 江西青峰药业有限公司 乙基硫酸铵在制备用于预防或治疗炎症性疾病药物中的应用
EP4514335A1 (en) 2022-04-28 2025-03-05 Alzheon, Inc. Tramiprosate for treating apoe4-related diseases
KR20250110352A (ko) 2022-12-02 2025-07-18 알제온, 인크. 트라미프로세이트를 이용하여 신경퇴행성 장애를 치료하는 방법

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Publication number Priority date Publication date Assignee Title
CA1140049A (en) * 1977-12-22 1983-01-25 Dke J.E. Helgstran Pharmaceutical preparations from derivatives of hydroxycarbonylphosphonic acid
US5087618A (en) * 1982-05-18 1992-02-11 University Of Florida Redox carriers for brain-specific drug delivery
US5463092A (en) * 1989-11-22 1995-10-31 Vestar, Inc. Lipid derivatives of phosphonacids for liposomal incorporation and method of use
US5276059A (en) * 1992-07-10 1994-01-04 The United States Of America As Represented By The Department Of Health And Human Services Inhibition of diseases associated with amyloid formation
US5840294A (en) * 1993-03-29 1998-11-24 Queen's University At Kingston Method for treating amyloidosis
US5643562A (en) * 1993-03-29 1997-07-01 Queen's University Of Kingston Method for treating amyloidosis
EP1060750B1 (en) * 1993-03-29 2005-12-07 Queen's University At Kingston Propane-1,3-disulfonic acid and its pharmaceutically acceptable salts for treating amyloidosis
US5869469A (en) * 1997-08-18 1999-02-09 Queen's University At Kingston Phosphonocarboxylate compounds for treating amyloidosis
NZ550116A (en) * 1997-08-18 2008-03-28 Neurochem Int Ltd Phosphono-carboxylate compounds for treating amyloidosis

Also Published As

Publication number Publication date
CY1113205T1 (el) 2016-04-13
JP2002502871A (ja) 2002-01-29
IL137751A0 (en) 2001-10-31
EP1054664B1 (en) 2012-08-08
WO1999040909A1 (en) 1999-08-19
JP4574845B2 (ja) 2010-11-04
NZ568553A (en) 2010-02-26
AU2437899A (en) 1999-08-30
EP1054664A1 (en) 2000-11-29
ES2392391T3 (es) 2012-12-10
CA2320224C (en) 2008-08-12
CA2320224A1 (en) 1999-08-19
HK1032915A1 (en) 2001-08-10
CA2632106A1 (en) 1999-08-19
MX2008014823A (es) 2009-03-06
DK1054664T3 (da) 2012-11-05
MXPA00007815A (es) 2002-04-24
PT1054664E (pt) 2012-11-02

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Legal Events

Date Code Title Description
PSEA Patent sealed
RENW Renewal (renewal fees accepted)
ASS Change of ownership

Owner name: BELLUS HEALTH INC., CA

Free format text: OLD OWNER(S): BELLUS HEALTH (INTERNATIONAL) LIMITED

RENW Renewal (renewal fees accepted)
ASS Change of ownership

Owner name: BHI LIMITED, CA

Effective date: 20130130

EXPY Patent expired