NZ535968A - Modified saccharides having improved stability in water - Google Patents

Modified saccharides having improved stability in water

Info

Publication number
NZ535968A
NZ535968A NZ535968A NZ53596803A NZ535968A NZ 535968 A NZ535968 A NZ 535968A NZ 535968 A NZ535968 A NZ 535968A NZ 53596803 A NZ53596803 A NZ 53596803A NZ 535968 A NZ535968 A NZ 535968A
Authority
NZ
New Zealand
Prior art keywords
saccharide
modified
group
capsular saccharide
groups
Prior art date
Application number
NZ535968A
Other languages
English (en)
Inventor
Paulo Costantino
Francesco Berti
Francesco Norelli
Antonella Bartoloni
Original Assignee
Chiron S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0207117A external-priority patent/GB0207117D0/en
Priority claimed from GB0220195A external-priority patent/GB0220195D0/en
Priority claimed from GB0229494A external-priority patent/GB0229494D0/en
Priority claimed from GB0230163A external-priority patent/GB0230163D0/en
Application filed by Chiron S filed Critical Chiron S
Publication of NZ535968A publication Critical patent/NZ535968A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/095Neisseria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505Inorganic adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031Proteins
    • A61K2039/6037Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Saccharide Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
NZ535968A 2002-03-26 2003-03-26 Modified saccharides having improved stability in water NZ535968A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB0207117A GB0207117D0 (en) 2002-03-26 2002-03-26 Modified saccharides having improved stability in water
GB0220195A GB0220195D0 (en) 2002-08-30 2002-08-30 Modified saccharides having improved stability in water
GB0229494A GB0229494D0 (en) 2002-12-18 2002-12-18 Modified saccharides having improved stability in water
GB0230163A GB0230163D0 (en) 2002-12-24 2002-12-24 Modified saccharides having improved stability in water
PCT/IB2003/001436 WO2003080678A1 (en) 2002-03-26 2003-03-26 Modified saccharides having improved stability in water

Publications (1)

Publication Number Publication Date
NZ535968A true NZ535968A (en) 2006-08-31

Family

ID=28457825

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ535968A NZ535968A (en) 2002-03-26 2003-03-26 Modified saccharides having improved stability in water

Country Status (14)

Country Link
EP (2) EP1777236B8 (enExample)
JP (2) JP2005526153A (enExample)
AT (1) ATE419278T1 (enExample)
BR (1) BR0308768A (enExample)
CA (1) CA2480389C (enExample)
CY (2) CY1108911T1 (enExample)
DE (1) DE60325565D1 (enExample)
DK (2) DK1490409T3 (enExample)
ES (2) ES2318117T3 (enExample)
HU (1) HUE030532T2 (enExample)
MX (1) MXPA04009339A (enExample)
NZ (1) NZ535968A (enExample)
PT (2) PT1490409E (enExample)
WO (1) WO2003080678A1 (enExample)

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RU2378010C2 (ru) 2003-10-02 2010-01-10 Новартис Вэксинес Энд Дайэгностикс С.Р.Л. Жидкие вакцины для множественных серогрупп менингококков
GB0406013D0 (en) 2004-03-17 2004-04-21 Chiron Srl Analysis of saccharide vaccines without interference
GB0500787D0 (en) 2005-01-14 2005-02-23 Chiron Srl Integration of meningococcal conjugate vaccination
GB0409745D0 (en) 2004-04-30 2004-06-09 Chiron Srl Compositions including unconjugated carrier proteins
DK1740217T3 (da) 2004-04-30 2011-09-26 Novartis Ag Meningokok-konjugat-vaccination
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GB0411387D0 (en) 2004-05-21 2004-06-23 Chiron Srl Analysis of saccharide length
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GB0713880D0 (en) 2007-07-17 2007-08-29 Novartis Ag Conjugate purification
SI2200642T1 (sl) 2007-10-19 2012-06-29 Novartis Ag Formulacije meningokoknega cepiva
NZ587382A (en) 2008-02-21 2012-01-12 Novartis Ag Meningococcal fhbp polypeptides
GB0822633D0 (en) 2008-12-11 2009-01-21 Novartis Ag Formulation
GB0822634D0 (en) 2008-12-11 2009-01-21 Novartis Ag Meningitis vaccines
CN102300585A (zh) 2008-12-17 2011-12-28 诺华有限公司 包含血红蛋白受体的脑膜炎球菌疫苗
ES2797504T3 (es) 2009-03-24 2020-12-02 Glaxosmithkline Biologicals Sa Proteína de enlace del factor H meningocócico utilizada como adyuvante
BRPI1009829A2 (pt) 2009-03-24 2016-11-16 Novartis Ag combinações de proteína de ligação de fator h meningocócico e conjugados de sacarídeos pneumocócicos
SG177310A1 (en) 2009-06-22 2012-02-28 Wyeth Llc Compositions and methods for preparing staphylococcus aureus serotype 5 and 8 capsular polysaccharide conjugate immunogenic compositions
PL2445522T3 (pl) 2009-06-22 2018-01-31 Wyeth Llc Kompozycje immunogenne antygenów Staphylococcus aureus
AU2010288240B2 (en) 2009-08-27 2014-03-27 Novartis Ag Hybrid polypeptides including meningococcal fHBP sequences
EP2483390A2 (en) 2009-09-30 2012-08-08 Novartis AG Expression of meningococcal fhbp polypeptides
CA2779816A1 (en) 2009-10-27 2011-05-05 Novartis Ag Modified meningococcal fhbp polypeptides
WO2011161653A1 (en) 2010-06-25 2011-12-29 Novartis Ag Combinations of meningococcal factor h binding proteins
SI2608805T2 (sl) 2010-08-23 2025-09-30 Wyeth Llc Stabilne formulacije antigenov rLP2086 neisserie meningitidis
US9057716B2 (en) 2010-09-04 2015-06-16 Novartis Ag Bactericidal antibody assays to assess immunogenicity and potency of meningococcal capsular saccharide vaccines
BR112013005329A2 (pt) 2010-09-10 2017-05-02 Wyeth Llc variantes não lipidadas de antígenos orf2086 de neisseria meningitidis
ES2681698T3 (es) 2011-03-02 2018-09-14 Glaxosmithkline Biologicals Sa Vacunas de combinación con menores dosis de antígeno y/o adyuvante
JP6088507B2 (ja) 2011-07-08 2017-03-01 ノバルティス アーゲー チロシンライゲーションの方法
AU2012335208B2 (en) 2011-11-07 2017-08-31 Glaxosmithkline Biologicals S.A. Carrier molecule comprising a spr0096 and a spr2021 antigen
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US20150125486A1 (en) 2012-03-08 2015-05-07 Novartis Ag Adjuvanted formulations of pediatric antigens
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GB201300707D0 (en) * 2013-01-15 2013-02-27 Novartis Ag Compounds and processes
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JP6786394B2 (ja) 2014-02-28 2020-11-18 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム 改変髄膜炎菌fHbpポリペプチド
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Also Published As

Publication number Publication date
AU2003216633A1 (en) 2003-10-08
HUE030532T2 (en) 2017-05-29
CY1108911T1 (el) 2014-07-02
DE60325565D1 (de) 2009-02-12
PT1490409E (pt) 2009-04-03
JP2010132925A (ja) 2010-06-17
ATE419278T1 (de) 2009-01-15
DK1777236T3 (en) 2017-02-27
WO2003080678A1 (en) 2003-10-02
MXPA04009339A (es) 2005-01-25
CA2480389C (en) 2012-10-09
EP1490409B1 (en) 2008-12-31
EP1490409A1 (en) 2004-12-29
CA2480389A1 (en) 2003-10-02
DK1490409T3 (da) 2009-03-23
ES2318117T3 (es) 2009-05-01
ES2616180T3 (es) 2017-06-09
JP5361767B2 (ja) 2013-12-04
EP1777236B8 (en) 2017-02-22
EP1777236B1 (en) 2016-11-30
PT1777236T (pt) 2017-02-13
BR0308768A (pt) 2005-02-15
CY1118584T1 (el) 2017-07-12
EP1777236A1 (en) 2007-04-25
JP2005526153A (ja) 2005-09-02

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Legal Events

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PSEA Patent sealed
RENW Renewal (renewal fees accepted)
ASS Change of ownership

Owner name: NOVARTIS VACCINES AND DIAGNOSTICS S.R.L., IT

Free format text: OLD OWNER(S): CHIRON S.R.L

RENW Renewal (renewal fees accepted)
RENW Renewal (renewal fees accepted)

Free format text: PATENT RENEWED FOR 3 YEARS UNTIL 26 MAR 2016 BY CPA GLOBAL

Effective date: 20130211

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Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 26 MAR 2017 BY THOMSON REUTERS

Effective date: 20160217

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Effective date: 20170221

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