NZ520762A - Peptide and peptidomimetic antagonists of a G protein coupled receptor in treatments for regulating fluid filtration in the kidney - Google Patents

Peptide and peptidomimetic antagonists of a G protein coupled receptor in treatments for regulating fluid filtration in the kidney

Info

Publication number
NZ520762A
NZ520762A NZ520762A NZ52076200A NZ520762A NZ 520762 A NZ520762 A NZ 520762A NZ 520762 A NZ520762 A NZ 520762A NZ 52076200 A NZ52076200 A NZ 52076200A NZ 520762 A NZ520762 A NZ 520762A
Authority
NZ
New Zealand
Prior art keywords
group
peptide
receptor
compound
leu
Prior art date
Application number
NZ520762A
Other languages
English (en)
Inventor
Krishna G Peri
Sylvain Chemtob
Original Assignee
Chu Sainte Justine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chu Sainte Justine filed Critical Chu Sainte Justine
Publication of NZ520762A publication Critical patent/NZ520762A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72Receptors; Cell surface antigens; Cell surface determinants for hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Toxicology (AREA)
  • Rheumatology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pipe Accessories (AREA)
  • Flanged Joints, Insulating Joints, And Other Joints (AREA)
  • Joints With Sleeves (AREA)
  • Water Treatment By Sorption (AREA)
  • Water Treatment By Electricity Or Magnetism (AREA)
NZ520762A 1999-12-06 2000-12-06 Peptide and peptidomimetic antagonists of a G protein coupled receptor in treatments for regulating fluid filtration in the kidney NZ520762A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US45548399A 1999-12-06 1999-12-06
PCT/CA2000/001445 WO2001042281A1 (en) 1999-12-06 2000-12-06 Compositions for treating abnormalities in glomerular filtration, patent ductus arteriosus and osteoporosis

Publications (1)

Publication Number Publication Date
NZ520762A true NZ520762A (en) 2005-02-25

Family

ID=23808998

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ520762A NZ520762A (en) 1999-12-06 2000-12-06 Peptide and peptidomimetic antagonists of a G protein coupled receptor in treatments for regulating fluid filtration in the kidney

Country Status (12)

Country Link
US (1) US7442763B2 (enExample)
EP (1) EP1244693B1 (enExample)
JP (1) JP2003516417A (enExample)
AT (1) ATE298346T1 (enExample)
AU (1) AU784630B2 (enExample)
CA (1) CA2396739A1 (enExample)
DE (1) DE60020997T2 (enExample)
ES (1) ES2246915T3 (enExample)
MX (1) MXPA02005626A (enExample)
NZ (1) NZ520762A (enExample)
WO (1) WO2001042281A1 (enExample)
ZA (1) ZA200205795B (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040235749A1 (en) * 1999-09-15 2004-11-25 Sylvain Chemtob G-protein coupled receptor antagonists
AU784630B2 (en) 1999-12-06 2006-05-18 Hopital Sainte-Justine Compositions for treating abnormalities in glomerular filtration, patent ductus arteriosus and osteoporosis
WO2003030911A1 (en) * 2001-10-08 2003-04-17 Medical Research Council Use of prostaglandin e synthase inhibitors, or ep2 or ep4 receptor antagonists, in the treatment of a pathological condition of the uterus
EP1450813B1 (en) * 2001-10-31 2007-08-29 Medical Research Council Antagonists of prostaglandin receptors ep2 and/or ep4 for the treatment of menorrhagia
US7414029B2 (en) 2002-05-23 2008-08-19 Theratechnologies, Inc. Antagonistic peptides of prostaglandin E2 receptor subtype EP4
JP2006506327A (ja) * 2002-05-23 2006-02-23 セラテクノロジーズ インコーポレイティド プロスタグランジンe2の受容体サブタイプep4のアンタゴニスト・ポリペプチド
EP1878741A3 (en) * 2002-05-23 2008-02-20 Theratechnologies Inc. Antagonistic peptides of prostaglandin E2 receptor subtype EP4
WO2004073589A2 (en) * 2003-02-24 2004-09-02 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with g-protein coupled receptor prostaglandin e2 ep4 (prostaglandin e2 ep4)
US8618054B2 (en) * 2004-05-05 2013-12-31 Valorisation-Rechereche Société en Commandite Interleukin-1 receptor antagonists, compositions, and methods of treatment
WO2013167582A1 (en) 2012-05-09 2013-11-14 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and pharmaceutical compositions for prevention or treatment of chronic obstructive pulmonary disease
US12036286B2 (en) 2021-03-18 2024-07-16 Seagen Inc. Selective drug release from internalized conjugates of biologically active compounds

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9019120D0 (en) * 1990-09-01 1990-10-17 Beecham Group Plc Novel compounds
AU4855393A (en) * 1992-09-10 1994-03-29 New York University Polypeptides of g-coupled receptor proteins, and compositions and methods thereof
CA2157510A1 (en) * 1993-03-05 1994-09-15 Howard M. Grey Hla-a2.1 binding peptides and their uses
US5869281A (en) 1993-06-25 1999-02-09 Merck Frosst Canada Inc. DNA encoding prostaglandin receptor FP
US5605814A (en) * 1993-08-31 1997-02-25 Merck Frosst Canada Inc. DNA encoding human prostaglandin receptor EP2
AU685187B2 (en) * 1993-10-29 1998-01-15 Incyte Pharmaceuticals, Inc. Chimeric proteins including protease nexin-1 variants
EP0756604A1 (en) * 1994-04-22 1997-02-05 THE UNITED STATES OF AMERICA, as represented by the Secretary of the Department of Health and Human Services Melanoma antigens
US5866679A (en) * 1994-06-28 1999-02-02 Merck & Co., Inc. Peptides
WO1996006856A1 (en) * 1994-08-31 1996-03-07 Robert Webber Dopamine receptor peptides and anti-peptide antibodies
CN1160115C (zh) * 1994-12-12 2004-08-04 奥默罗斯公司 用于抑制疼痛,炎症和痉挛的冲洗液和方法
EP0870198A4 (en) 1995-01-25 2001-04-04 Cor Therapeutics Inc RECOMBINANT C140 RECEPTOR, ITS AGONISTS AND ANTAGONISTS, AND NUCLEIC ACIDS ENCODING THE RECEPTOR
US5877155A (en) * 1995-03-17 1999-03-02 The Research Foundation Of State University Of New York Mimotopes and anti-mimotopes of human platelet glycoprotein Ib/IX
US6117839A (en) * 1995-06-07 2000-09-12 Gensci Regeneration Sciences, Inc. Bone stimulating factor
AU2658897A (en) * 1996-03-21 1997-10-10 Epimmune, Inc. Hla-a2.1 binding peptides and their uses
WO1998010651A1 (en) * 1996-09-12 1998-03-19 Merck & Co., Inc. Conjugates useful in the treatment of prostate cancer
US5955575A (en) * 1997-12-22 1999-09-21 Hopital Sainte-Justine Antagonists of G-protein-coupled receptor
AUPP320998A0 (en) * 1998-04-27 1998-05-21 Walter And Eliza Hall Institute Of Medical Research, The Tyrosine phosphatase IA-2 T-cell epitopes
US6984719B1 (en) * 1998-09-17 2006-01-10 Hospital Sainte-Justine Peptide antagonists of prostaglandin F2α receptor
US20040235749A1 (en) * 1999-09-15 2004-11-25 Sylvain Chemtob G-protein coupled receptor antagonists
AU784630B2 (en) 1999-12-06 2006-05-18 Hopital Sainte-Justine Compositions for treating abnormalities in glomerular filtration, patent ductus arteriosus and osteoporosis

Also Published As

Publication number Publication date
EP1244693A1 (en) 2002-10-02
US20030017988A1 (en) 2003-01-23
WO2001042281A1 (en) 2001-06-14
DE60020997D1 (de) 2005-07-28
ATE298346T1 (de) 2005-07-15
JP2003516417A (ja) 2003-05-13
ES2246915T3 (es) 2006-03-01
AU2134001A (en) 2001-06-18
AU784630B2 (en) 2006-05-18
DE60020997T2 (de) 2006-05-24
CA2396739A1 (en) 2001-06-14
MXPA02005626A (es) 2004-09-10
EP1244693B1 (en) 2005-06-22
US7442763B2 (en) 2008-10-28
ZA200205795B (en) 2007-01-31

Similar Documents

Publication Publication Date Title
JP5502480B2 (ja) 生物活性ペプチド及びその使用方法
US7943728B2 (en) Disintegrin variants and their use in treating osteoporosis-induced bone loss and angiogenesis-related diseases
AU784630B2 (en) Compositions for treating abnormalities in glomerular filtration, patent ductus arteriosus and osteoporosis
US6482609B1 (en) Isolated human EDG-4 receptor and polynucletide encoding said receptor
JP2010532988A (ja) 生物活性ペプチドおよびその使用方法
US20040023853A1 (en) Antagonistic peptides of prostaglandin E2 receptor subtype EP4
CA3054169C (en) Compositions and methods for improving sexual function in a male with benign prostatic hyperplasia
JP2006506327A5 (enExample)
ES2393462T3 (es) Péptido útil para inhibir la actividad del receptor de prosta-glandina F2X
US9155795B2 (en) CXCR4 receptor compounds
WO1997011091A1 (fr) Nouveaux composes peptidiques et leurs compositions medicinales
CA2342960C (en) G protein-coupled receptor antagonists
WO2001089582A1 (en) Preventives and remedies for pulmonary hypertension
US6191103B1 (en) Methods for enhancing thrombolysis in a mammal
JP2008013436A (ja) 血管形成促進剤
AU6611100A (en) Methods of inhibiting osteoclastogenesis
US7414029B2 (en) Antagonistic peptides of prostaglandin E2 receptor subtype EP4
JPH10271997A (ja) 新規Fasリガンド様タンパク質およびそのDNA
WO2023183667A1 (en) Urokinase-type plasminogen activator receptor binding peptides and methods of use
TW201350500A (zh) 用於抑制血小板聚集之胜肽化合物
WO2020000063A1 (en) Rheumatoid arthritis treatment
EP1878741A2 (en) Antagonistic peptides of prostaglandin E2 receptor subtype EP4
JP2002047203A (ja) 肺高血圧症予防・治療剤
JP2002355077A (ja) カスパーゼ3阻害剤
JPWO2000071151A1 (ja) 肝臓機能調節剤

Legal Events

Date Code Title Description
RENP Pct: late entry into national phase requested

Effective date: 20020813

LENP Pct: late entry into national phase granted

Effective date: 20020813

RENW Renewal (renewal fees accepted)
PSEA Patent sealed
RENW Renewal (renewal fees accepted)