NZ240325A - Formation of internucleoside linkages involving forming a linkage containing a trivalent phosphorus and then oxidising it to a pentavalent phosphorus - Google Patents
Formation of internucleoside linkages involving forming a linkage containing a trivalent phosphorus and then oxidising it to a pentavalent phosphorusInfo
- Publication number
- NZ240325A NZ240325A NZ240325A NZ24032591A NZ240325A NZ 240325 A NZ240325 A NZ 240325A NZ 240325 A NZ240325 A NZ 240325A NZ 24032591 A NZ24032591 A NZ 24032591A NZ 240325 A NZ240325 A NZ 240325A
- Authority
- NZ
- New Zealand
- Prior art keywords
- phosphorus
- oxidising
- formation
- internucleoside linkages
- linkage containing
- Prior art date
Links
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 title 2
- 229910052698 phosphorus Inorganic materials 0.000 title 2
- 239000011574 phosphorus Substances 0.000 title 2
- 230000015572 biosynthetic process Effects 0.000 title 1
- 238000000034 method Methods 0.000 abstract 2
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 230000008878 coupling Effects 0.000 abstract 1
- 238000010168 coupling process Methods 0.000 abstract 1
- 238000005859 coupling reaction Methods 0.000 abstract 1
- YACKEPLHDIMKIO-UHFFFAOYSA-N methylphosphonic acid Chemical compound CP(O)(O)=O YACKEPLHDIMKIO-UHFFFAOYSA-N 0.000 abstract 1
- 239000007800 oxidant agent Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 230000002194 synthesizing effect Effects 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US60579090A | 1990-10-26 | 1990-10-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ240325A true NZ240325A (en) | 1993-06-25 |
Family
ID=24425218
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ240325A NZ240325A (en) | 1990-10-26 | 1991-10-23 | Formation of internucleoside linkages involving forming a linkage containing a trivalent phosphorus and then oxidising it to a pentavalent phosphorus |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US5726300A (enExample) |
| EP (1) | EP0592434B1 (enExample) |
| JP (1) | JPH06509542A (enExample) |
| AT (1) | ATE171947T1 (enExample) |
| AU (1) | AU669103B2 (enExample) |
| CA (1) | CA2094803A1 (enExample) |
| DE (1) | DE69130331T2 (enExample) |
| DK (1) | DK0592434T3 (enExample) |
| ES (1) | ES2124231T3 (enExample) |
| IE (1) | IE913761A1 (enExample) |
| IL (1) | IL99844A (enExample) |
| NZ (1) | NZ240325A (enExample) |
| TW (1) | TW216423B (enExample) |
| WO (1) | WO1992007864A1 (enExample) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU3250093A (en) | 1991-12-12 | 1993-07-19 | Gilead Sciences, Inc. | Nuclease stable and binding competent oligomers and methods for their use |
| WO1994001446A2 (en) * | 1992-07-09 | 1994-01-20 | Beckman Instruments, Inc. | Derivatized organic solid support for nucleic acid synthesis |
| FR2707296B1 (fr) * | 1993-07-09 | 1995-09-29 | Genset Sa | Procédé de synthèse d'acides nucléiques sur support solide et composés utiles notamment comme support solide dans ledit procédé. |
| US5739309A (en) * | 1993-07-19 | 1998-04-14 | Gen-Probe Incorporated | Enhancement of oligonucleotide inhibition of protein production, cell proliferation and / or multiplication of infectious disease pathogens |
| WO1995003427A2 (en) * | 1993-07-19 | 1995-02-02 | Gen-Probe Incorporated | Oligonucleotide screening assay |
| WO1995003407A2 (en) * | 1993-07-19 | 1995-02-02 | Gen-Probe Incorporated | Oligonucleotides with activity against human immunodeficiency virus |
| US5733781A (en) | 1994-07-19 | 1998-03-31 | Gen-Probe Incorporated | Oligonucleotides and methods for inhibiting propagation of human immunodeficiency virus |
| JP3124036B2 (ja) * | 1995-01-19 | 2001-01-15 | ジェン−プローブ・インコーポレーテッド | ライム病関連ボレリアに対する核酸増幅オリゴヌクレオチドおよびプローブ |
| US5747470A (en) * | 1995-06-07 | 1998-05-05 | Gen-Probe Incorporated | Method for inhibiting cellular proliferation using antisense oligonucleotides to gp130 mRNA |
| US5747252A (en) | 1995-06-07 | 1998-05-05 | Gen-Probe Incorporated | Nucleic acid probes and amplification oligonucleotides for Neisseria species |
| US5674995A (en) * | 1995-06-07 | 1997-10-07 | Gen-Probe Incorporated | Oligonucleotides specific for cytokine signal transducer gp130 mRNA |
| US5716846A (en) * | 1995-06-07 | 1998-02-10 | Gen-Probe Incorporated | Method for inhibiting cellular proliferation using antisense oligonucleotides to interleukin-6 receptor mRNA |
| US5731148A (en) * | 1995-06-07 | 1998-03-24 | Gen-Probe Incorporated | Adduct protection assay |
| US6025133A (en) * | 1996-12-30 | 2000-02-15 | Gen-Probe Incorporated | Promoter-sequestered oligonucleoside and method of use |
| US6146833A (en) * | 1997-02-11 | 2000-11-14 | Beckman Coulter, Inc. | Polymeric reagents for immobilizing biopolymers |
| US7435390B2 (en) * | 2001-01-26 | 2008-10-14 | Third Wave Technologies, Inc. | Nucleic acid synthesizers |
| US6932943B1 (en) | 2001-01-26 | 2005-08-23 | Third Wave Technologies | Nucleic acid synthesizers |
| US20030072689A1 (en) * | 2001-08-15 | 2003-04-17 | Third Wave Technologies, Inc. | Polymer synthesizer |
| AU2007281143B2 (en) | 2006-08-01 | 2011-05-19 | Gen-Probe Incorporated | Methods of nonspecific target capture of nucleic acids |
| CN102037144B (zh) | 2008-04-01 | 2013-09-25 | 生物检索技术股份有限公司 | 稳定化的核酸暗猝灭剂-荧光团探针 |
| US10913767B2 (en) * | 2010-04-22 | 2021-02-09 | Alnylam Pharmaceuticals, Inc. | Oligonucleotides comprising acyclic and abasic nucleosides and analogs |
| US9403865B2 (en) | 2012-08-15 | 2016-08-02 | Ionis Pharmaceuticals, Inc. | Method of preparing oligomeric compounds using modified capping protocols |
| EP3140286B1 (en) | 2014-05-09 | 2018-12-26 | Biosearch Technologies, Inc. | Cosmic quenchers |
| WO2016160646A1 (en) * | 2015-04-02 | 2016-10-06 | Merck Sharp & Dohme Corp. | Process for making phosphoramidate protected nucleoside compounds |
| PT3283499T (pt) | 2015-04-15 | 2022-08-23 | Biosearch Tech Inc | Sondas de extintor dual |
| CA3062075C (en) | 2017-05-11 | 2024-04-02 | Gen-Probe Incorporated | Compositions and methods for isolating target nucleic acids |
| CN116287111A (zh) | 2019-11-14 | 2023-06-23 | 简·探针公司 | 用于捕获靶核酸的组合物和方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4458066A (en) * | 1980-02-29 | 1984-07-03 | University Patents, Inc. | Process for preparing polynucleotides |
| US4500707A (en) * | 1980-02-29 | 1985-02-19 | University Patents, Inc. | Nucleosides useful in the preparation of polynucleotides |
| US4469863A (en) * | 1980-11-12 | 1984-09-04 | Ts O Paul O P | Nonionic nucleic acid alkyl and aryl phosphonates and processes for manufacture and use thereof |
| US4415732A (en) * | 1981-03-27 | 1983-11-15 | University Patents, Inc. | Phosphoramidite compounds and processes |
| US4668777A (en) * | 1981-03-27 | 1987-05-26 | University Patents, Inc. | Phosphoramidite nucleoside compounds |
| DE3329892A1 (de) * | 1983-08-18 | 1985-03-07 | Köster, Hubert, Prof. Dr., 2000 Hamburg | Verfahren zur herstellung von oligonucleotiden |
| US4923901A (en) * | 1987-09-04 | 1990-05-08 | Millipore Corporation | Membranes with bound oligonucleotides and peptides |
-
1991
- 1991-10-21 JP JP3518321A patent/JPH06509542A/ja active Pending
- 1991-10-21 CA CA002094803A patent/CA2094803A1/en not_active Abandoned
- 1991-10-21 EP EP91919675A patent/EP0592434B1/en not_active Expired - Lifetime
- 1991-10-21 DE DE69130331T patent/DE69130331T2/de not_active Expired - Fee Related
- 1991-10-21 AU AU88753/91A patent/AU669103B2/en not_active Ceased
- 1991-10-21 WO PCT/US1991/007630 patent/WO1992007864A1/en not_active Ceased
- 1991-10-21 ES ES91919675T patent/ES2124231T3/es not_active Expired - Lifetime
- 1991-10-21 DK DK91919675T patent/DK0592434T3/da active
- 1991-10-21 AT AT91919675T patent/ATE171947T1/de not_active IP Right Cessation
- 1991-10-23 NZ NZ240325A patent/NZ240325A/xx not_active IP Right Cessation
- 1991-10-24 IL IL9984491A patent/IL99844A/en not_active IP Right Cessation
- 1991-10-25 IE IE376191A patent/IE913761A1/en not_active Application Discontinuation
-
1992
- 1992-01-14 TW TW081100215A patent/TW216423B/zh active
-
1994
- 1994-06-15 US US08/260,392 patent/US5726300A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2094803A1 (en) | 1992-04-27 |
| US5726300A (en) | 1998-03-10 |
| DE69130331T2 (de) | 1999-03-04 |
| AU669103B2 (en) | 1996-05-30 |
| EP0592434A1 (en) | 1994-04-20 |
| DE69130331D1 (de) | 1998-11-12 |
| IE913761A1 (en) | 1992-05-22 |
| JPH06509542A (ja) | 1994-10-27 |
| IL99844A (en) | 1995-07-31 |
| ATE171947T1 (de) | 1998-10-15 |
| ES2124231T3 (es) | 1999-02-01 |
| EP0592434A4 (en) | 1996-04-24 |
| DK0592434T3 (da) | 1999-06-21 |
| AU8875391A (en) | 1992-05-26 |
| EP0592434B1 (en) | 1998-10-07 |
| TW216423B (enExample) | 1993-11-21 |
| WO1992007864A1 (en) | 1992-05-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RENW | Renewal (renewal fees accepted) | ||
| RENW | Renewal (renewal fees accepted) | ||
| EXPY | Patent expired |