NZ235582A - N-benzyl(or phenyl)-n'-(4-phenylquinolin-3-yl) urea derivatives, preparation and pharmaceutical compositions thereof - Google Patents
N-benzyl(or phenyl)-n'-(4-phenylquinolin-3-yl) urea derivatives, preparation and pharmaceutical compositions thereofInfo
- Publication number
- NZ235582A NZ235582A NZ235582A NZ23558290A NZ235582A NZ 235582 A NZ235582 A NZ 235582A NZ 235582 A NZ235582 A NZ 235582A NZ 23558290 A NZ23558290 A NZ 23558290A NZ 235582 A NZ235582 A NZ 235582A
- Authority
- NZ
- New Zealand
- Prior art keywords
- dihydro
- oxo
- methyl
- compound
- chlorophenyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Obesity (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Measurement Of Radiation (AREA)
- Holo Graphy (AREA)
- Detergent Compositions (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP26278289 | 1989-10-06 | ||
| JP32229089 | 1989-12-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ235582A true NZ235582A (en) | 1992-03-26 |
Family
ID=26545706
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ235582A NZ235582A (en) | 1989-10-06 | 1990-10-05 | N-benzyl(or phenyl)-n'-(4-phenylquinolin-3-yl) urea derivatives, preparation and pharmaceutical compositions thereof |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US5223513A (enExample) |
| EP (1) | EP0421456B1 (enExample) |
| KR (1) | KR910007883A (enExample) |
| CN (1) | CN1050715A (enExample) |
| AT (1) | ATE116301T1 (enExample) |
| AU (1) | AU629048B2 (enExample) |
| CA (1) | CA2026890C (enExample) |
| DE (1) | DE69015541T2 (enExample) |
| FI (1) | FI904915A7 (enExample) |
| HU (1) | HUT55364A (enExample) |
| IE (1) | IE903454A1 (enExample) |
| IL (1) | IL95839A (enExample) |
| NO (1) | NO904300L (enExample) |
| NZ (1) | NZ235582A (enExample) |
| PT (1) | PT95515A (enExample) |
| RU (1) | RU2001910C1 (enExample) |
| TW (1) | TW205037B (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH03181465A (ja) * | 1989-12-11 | 1991-08-07 | Takeda Chem Ind Ltd | キノリン誘導体 |
| CZ395592A3 (en) * | 1991-04-26 | 1994-02-16 | Pfizer | 4-aryl-3-(heteroarylureido)quinoline derivatives, process of their preparation and use |
| JP2668163B2 (ja) * | 1992-01-23 | 1997-10-27 | ファイザー インク． | コレステロール血症および抗アテローム動脈硬化症薬としての４−アリール−３−（ヘテロアリールウレイド）−１，２−ジヒドロ−２−オキソ−キノリン誘導体 |
| TW241258B (enExample) * | 1992-04-15 | 1995-02-21 | Takeda Pharm Industry Co Ltd | |
| US6001860A (en) * | 1992-05-28 | 1999-12-14 | Pfizer Inc. | N-aryl and N-heteroarylurea derivatives as inhibitors of acyl coenzyme A: Cholesterol acyl transferase (ACAT) |
| NO179904C (no) * | 1992-09-04 | 1997-01-08 | Takeda Chemical Industries Ltd | Kondenserte heterocykliske forbindelser og deres anvendelse |
| US5565472A (en) * | 1992-12-21 | 1996-10-15 | Pfizer Inc. | 4-aryl-3-(heteroarylureido)-1,2-dihydro-2-oxo-quinoline derivatives as antihypercholesterolemic and antiatherosclerotic agents |
| NZ264063A (en) * | 1993-08-13 | 1995-11-27 | Nihon Nohyaku Co Ltd | N-(2-phenylpyrid-3-yl)- and n-(4-phenylpyrimidin-5-yl)-n'-phenylurea derivatives and pharmaceutical compositions |
| TW263498B (enExample) * | 1993-11-10 | 1995-11-21 | Takeda Pharm Industry Co Ltd | |
| US6133326A (en) | 1994-08-31 | 2000-10-17 | Pfizer Inc | Compositions and methods for decreasing sebum production |
| US5843957A (en) * | 1995-05-19 | 1998-12-01 | Sumitomo Pharmaceuticals Company, Ltd. | Naphthyridine derivatives |
| WO1999009983A1 (en) * | 1997-08-28 | 1999-03-04 | Bristol-Myers Squibb Company | 4-aryl-3-aminoquinoline-2-one derivatives as potassium channel modulators |
| US6452008B2 (en) | 1998-02-25 | 2002-09-17 | Sumitomo Pharmaceuticals Company, Limited | Pyridone derivatives and process for preparing the same |
| CA2321237A1 (en) | 1998-02-25 | 1999-09-02 | Masami Muraoka | Pyridone derivatives and process for producing the same |
| DK1133474T3 (da) * | 1998-12-04 | 2007-04-10 | Bristol Myers Squibb Co | 3-Substituerede 4-arylquinolin-2-onderivater som kaliumkanal-modulatorer |
| BR0107954A (pt) | 2000-02-02 | 2002-10-22 | Warner Lambert Co | Inibidores duplos de sìntese de éster de colesterol e éster de cera para distúrbios de glândula sebácea |
| CN1234691C (zh) * | 2001-03-02 | 2006-01-04 | 住友化学工业株式会社 | 喹啉－3－羧酸化合物的制备方法 |
| PL366584A1 (en) * | 2001-04-30 | 2005-02-07 | Pfizer Products Inc. | Compounds useful as intermediates |
| CN1856470A (zh) | 2003-09-23 | 2006-11-01 | 默克公司 | 喹啉钾通道抑制剂 |
| BR112014010644A2 (pt) * | 2011-11-04 | 2017-04-25 | Hoffmann La Roche | novos derivados de aril-quinolina |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1216878B (de) * | 1963-04-02 | 1966-05-18 | Cassella Farbwerke Mainkur Ag | Verfahren zur Herstellung von coronargefaesserweiternden Derivaten des 7-Hydroxy-2-oxo-1, 2-dihydrochinolins |
| NO133758C (enExample) * | 1970-04-04 | 1976-06-23 | Takeda Chemical Industries Ltd | |
| JPS555502B1 (enExample) * | 1971-07-31 | 1980-02-07 | ||
| US4530931A (en) * | 1983-01-03 | 1985-07-23 | Usv Pharmaceutical Corp. | 8-Quinoline carbanilates for the inhibition of lipolysis |
| DE3586445T2 (de) * | 1984-06-26 | 1993-01-14 | Merck & Co Inc | Kondensierte benzo-laktam-verbindungen und deren pharmazeutische zusammensetzungen. |
| IE892088L (en) * | 1988-07-12 | 1990-01-12 | William Henry Deryk Morris | Quinoline derivatives, their production and use |
-
1990
- 1990-09-20 TW TW079107912A patent/TW205037B/zh active
- 1990-09-25 US US07/587,795 patent/US5223513A/en not_active Expired - Fee Related
- 1990-09-25 IE IE345490A patent/IE903454A1/en unknown
- 1990-09-28 AU AU63707/90A patent/AU629048B2/en not_active Ceased
- 1990-09-28 IL IL9583990A patent/IL95839A/en not_active IP Right Cessation
- 1990-10-03 NO NO90904300A patent/NO904300L/no unknown
- 1990-10-04 PT PT95515A patent/PT95515A/pt not_active Application Discontinuation
- 1990-10-04 CA CA002026890A patent/CA2026890C/en not_active Expired - Fee Related
- 1990-10-05 NZ NZ235582A patent/NZ235582A/en unknown
- 1990-10-05 FI FI904915A patent/FI904915A7/fi not_active Application Discontinuation
- 1990-10-05 CN CN90108222A patent/CN1050715A/zh active Pending
- 1990-10-05 AT AT90119128T patent/ATE116301T1/de not_active IP Right Cessation
- 1990-10-05 DE DE69015541T patent/DE69015541T2/de not_active Expired - Fee Related
- 1990-10-05 HU HU906360A patent/HUT55364A/hu unknown
- 1990-10-05 RU SU904831426A patent/RU2001910C1/ru active
- 1990-10-05 EP EP90119128A patent/EP0421456B1/en not_active Expired - Lifetime
- 1990-10-06 KR KR1019900015908A patent/KR910007883A/ko not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU6370790A (en) | 1991-04-11 |
| EP0421456A3 (en) | 1991-05-29 |
| JPH03223254A (ja) | 1991-10-02 |
| NO904300L (no) | 1991-04-08 |
| IL95839A (en) | 1995-03-15 |
| DE69015541D1 (de) | 1995-02-09 |
| US5223513A (en) | 1993-06-29 |
| EP0421456A2 (en) | 1991-04-10 |
| CA2026890A1 (en) | 1991-04-07 |
| DE69015541T2 (de) | 1995-06-01 |
| HUT55364A (en) | 1991-05-28 |
| RU2001910C1 (ru) | 1993-10-30 |
| AU629048B2 (en) | 1992-09-24 |
| KR910007883A (ko) | 1991-05-30 |
| PT95515A (pt) | 1991-08-14 |
| IE903454A1 (en) | 1991-04-10 |
| TW205037B (enExample) | 1993-05-01 |
| EP0421456B1 (en) | 1994-12-28 |
| HU906360D0 (en) | 1991-04-29 |
| ATE116301T1 (de) | 1995-01-15 |
| IL95839A0 (en) | 1991-06-30 |
| NO904300D0 (no) | 1990-10-03 |
| FI904915A7 (fi) | 1991-04-07 |
| CA2026890C (en) | 2001-09-18 |
| CN1050715A (zh) | 1991-04-17 |
| FI904915A0 (fi) | 1990-10-05 |
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