NZ235582A - N-benzyl(or phenyl)-n'-(4-phenylquinolin-3-yl) urea derivatives, preparation and pharmaceutical compositions thereof - Google Patents

N-benzyl(or phenyl)-n'-(4-phenylquinolin-3-yl) urea derivatives, preparation and pharmaceutical compositions thereof

Info

Publication number
NZ235582A
NZ235582A NZ235582A NZ23558290A NZ235582A NZ 235582 A NZ235582 A NZ 235582A NZ 235582 A NZ235582 A NZ 235582A NZ 23558290 A NZ23558290 A NZ 23558290A NZ 235582 A NZ235582 A NZ 235582A
Authority
NZ
New Zealand
Prior art keywords
dihydro
oxo
methyl
compound
chlorophenyl
Prior art date
Application number
NZ235582A
Other languages
English (en)
Inventor
Kanji Meguro
Hitoshi Ikeda
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of NZ235582A publication Critical patent/NZ235582A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Obesity (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Detergent Compositions (AREA)
  • Measurement Of Radiation (AREA)
  • Holo Graphy (AREA)
  • Quinoline Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NZ235582A 1989-10-06 1990-10-05 N-benzyl(or phenyl)-n'-(4-phenylquinolin-3-yl) urea derivatives, preparation and pharmaceutical compositions thereof NZ235582A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP26278289 1989-10-06
JP32229089 1989-12-11

Publications (1)

Publication Number Publication Date
NZ235582A true NZ235582A (en) 1992-03-26

Family

ID=26545706

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ235582A NZ235582A (en) 1989-10-06 1990-10-05 N-benzyl(or phenyl)-n'-(4-phenylquinolin-3-yl) urea derivatives, preparation and pharmaceutical compositions thereof

Country Status (17)

Country Link
US (1) US5223513A (OSRAM)
EP (1) EP0421456B1 (OSRAM)
KR (1) KR910007883A (OSRAM)
CN (1) CN1050715A (OSRAM)
AT (1) ATE116301T1 (OSRAM)
AU (1) AU629048B2 (OSRAM)
CA (1) CA2026890C (OSRAM)
DE (1) DE69015541T2 (OSRAM)
FI (1) FI904915A7 (OSRAM)
HU (1) HUT55364A (OSRAM)
IE (1) IE903454A1 (OSRAM)
IL (1) IL95839A (OSRAM)
NO (1) NO904300L (OSRAM)
NZ (1) NZ235582A (OSRAM)
PT (1) PT95515A (OSRAM)
RU (1) RU2001910C1 (OSRAM)
TW (1) TW205037B (OSRAM)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03181465A (ja) * 1989-12-11 1991-08-07 Takeda Chem Ind Ltd キノリン誘導体
FI934710A7 (fi) * 1991-04-26 1993-10-25 Pfizer 4-aryyli-3-(heteroaryyliureido)kinoliinijohdannaisia
WO1993015058A1 (en) * 1992-01-23 1993-08-05 Pfizer Inc. 4-aryl-3-(heteroarylureido)-1,2-dihydro-2-oxo-quinoline derivatives as antihypercholesterolemic and antiatherosclerotic agents
TW241258B (OSRAM) * 1992-04-15 1995-02-21 Takeda Pharm Industry Co Ltd
US6001860A (en) * 1992-05-28 1999-12-14 Pfizer Inc. N-aryl and N-heteroarylurea derivatives as inhibitors of acyl coenzyme A: Cholesterol acyl transferase (ACAT)
NO179904C (no) * 1992-09-04 1997-01-08 Takeda Chemical Industries Ltd Kondenserte heterocykliske forbindelser og deres anvendelse
US5565472A (en) * 1992-12-21 1996-10-15 Pfizer Inc. 4-aryl-3-(heteroarylureido)-1,2-dihydro-2-oxo-quinoline derivatives as antihypercholesterolemic and antiatherosclerotic agents
NZ264063A (en) * 1993-08-13 1995-11-27 Nihon Nohyaku Co Ltd N-(2-phenylpyrid-3-yl)- and n-(4-phenylpyrimidin-5-yl)-n'-phenylurea derivatives and pharmaceutical compositions
TW263498B (OSRAM) * 1993-11-10 1995-11-21 Takeda Pharm Industry Co Ltd
US6133326A (en) 1994-08-31 2000-10-17 Pfizer Inc Compositions and methods for decreasing sebum production
US5843957A (en) * 1995-05-19 1998-12-01 Sumitomo Pharmaceuticals Company, Ltd. Naphthyridine derivatives
US5972961A (en) * 1997-08-28 1999-10-26 Bristol-Myers Squibb Company 4-aryl-3-aminoquinoline-2-one derivatives as potassium channel modulators
US6452008B2 (en) 1998-02-25 2002-09-17 Sumitomo Pharmaceuticals Company, Limited Pyridone derivatives and process for preparing the same
AU2547399A (en) 1998-02-25 1999-09-15 Sumitomo Pharmaceuticals Company, Limited Pyridone derivatives and process for producing the same
AU755202B2 (en) * 1998-12-04 2002-12-05 Bristol-Myers Squibb Company 3-substituted-4-arylquinolin-2-one derivatives as potassium channel modulators
UA75345C2 (en) 2000-02-02 2006-04-17 Warner Lambert Co Pharmaceutical composition for topical use intended for treating sebaceous gland disorders and methods of treating acnes using this composition
CA2439663C (en) * 2001-03-02 2012-04-03 Sumika Fine Chemicals Co., Ltd. Process for producing quinoline-3-carboxylic acid compound
CA2445693A1 (en) * 2001-04-30 2002-11-07 Pfizer Products Inc. Compounds useful as intermediates for 4-aminoquinoline derivatives
JP4794445B2 (ja) 2003-09-23 2011-10-19 メルク・シャープ・エンド・ドーム・コーポレイション キノリンカリウムチャネル阻害剤
ES2609773T3 (es) * 2011-11-04 2017-04-24 F. Hoffmann-La Roche Ag Nuevos derivados de arilquinolina

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1216878B (de) * 1963-04-02 1966-05-18 Cassella Farbwerke Mainkur Ag Verfahren zur Herstellung von coronargefaesserweiternden Derivaten des 7-Hydroxy-2-oxo-1, 2-dihydrochinolins
NO133758C (OSRAM) * 1970-04-04 1976-06-23 Takeda Chemical Industries Ltd
JPS555502B1 (OSRAM) * 1971-07-31 1980-02-07
US4530931A (en) * 1983-01-03 1985-07-23 Usv Pharmaceutical Corp. 8-Quinoline carbanilates for the inhibition of lipolysis
EP0166354B1 (en) * 1984-06-26 1992-08-05 Merck & Co. Inc. Benzofused lactam compounds and pharmaceutical compositions containing them
IE892088L (en) * 1988-07-12 1990-01-12 William Henry Deryk Morris Quinoline derivatives, their production and use

Also Published As

Publication number Publication date
IE903454A1 (en) 1991-04-10
HU906360D0 (en) 1991-04-29
NO904300L (no) 1991-04-08
KR910007883A (ko) 1991-05-30
CN1050715A (zh) 1991-04-17
FI904915A0 (fi) 1990-10-05
IL95839A0 (en) 1991-06-30
TW205037B (OSRAM) 1993-05-01
IL95839A (en) 1995-03-15
EP0421456B1 (en) 1994-12-28
RU2001910C1 (ru) 1993-10-30
JPH03223254A (ja) 1991-10-02
PT95515A (pt) 1991-08-14
ATE116301T1 (de) 1995-01-15
CA2026890C (en) 2001-09-18
AU6370790A (en) 1991-04-11
EP0421456A3 (en) 1991-05-29
DE69015541D1 (de) 1995-02-09
US5223513A (en) 1993-06-29
AU629048B2 (en) 1992-09-24
CA2026890A1 (en) 1991-04-07
EP0421456A2 (en) 1991-04-10
NO904300D0 (no) 1990-10-03
DE69015541T2 (de) 1995-06-01
HUT55364A (en) 1991-05-28
FI904915A7 (fi) 1991-04-07

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