NZ206293A - (n-(2-chloroethyl)-n-nitrosoureido)-methyl phosphonic acid derivatives and pharmaceutical compositions - Google Patents
(n-(2-chloroethyl)-n-nitrosoureido)-methyl phosphonic acid derivatives and pharmaceutical compositionsInfo
- Publication number
- NZ206293A NZ206293A NZ206293A NZ20629383A NZ206293A NZ 206293 A NZ206293 A NZ 206293A NZ 206293 A NZ206293 A NZ 206293A NZ 20629383 A NZ20629383 A NZ 20629383A NZ 206293 A NZ206293 A NZ 206293A
- Authority
- NZ
- New Zealand
- Prior art keywords
- chloroethyl
- general formula
- radical
- exchangeable
- nitrosoureido
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
- C07F9/3804—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se) not used, see subgroups
- C07F9/3808—Acyclic saturated acids which can have further substituents on alkyl
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8219199A FR2536075B1 (fr) | 1982-11-17 | 1982-11-17 | Nouveaux derives de la nitrosouree, leur procede de preparation et les compositions pharmaceutiques les renfermant |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ206293A true NZ206293A (en) | 1987-02-20 |
Family
ID=9279241
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ206293A NZ206293A (en) | 1982-11-17 | 1983-11-16 | (n-(2-chloroethyl)-n-nitrosoureido)-methyl phosphonic acid derivatives and pharmaceutical compositions |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US4567169A (da) |
| EP (1) | EP0117959B1 (da) |
| JP (1) | JPS59106497A (da) |
| AT (1) | ATE21905T1 (da) |
| AU (1) | AU557139B2 (da) |
| CA (1) | CA1204442A (da) |
| DE (1) | DE3365900D1 (da) |
| DK (1) | DK169340B1 (da) |
| ES (1) | ES8501772A1 (da) |
| FR (1) | FR2536075B1 (da) |
| IE (1) | IE56259B1 (da) |
| IL (1) | IL70253A (da) |
| MA (1) | MA19952A1 (da) |
| NO (1) | NO163409C (da) |
| NZ (1) | NZ206293A (da) |
| OA (1) | OA07589A (da) |
| PT (1) | PT77666B (da) |
| SU (1) | SU1303024A3 (da) |
| ZA (1) | ZA838558B (da) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2567129B1 (fr) * | 1984-07-06 | 1986-12-05 | Adir | Nouveaux derives de l'oxaazaphosphorine, leur procede de preparation et les compositions pharmaceutiques les renfermant |
| IT1246778B (it) * | 1991-04-12 | 1994-11-26 | Boehringer Mannheim Italia | Nitrosocarbamoil derivati di acidi gem-difosfonici, un processo per la loro preparazione e composizioni farmaceutiche che li contengono |
| US5298499A (en) * | 1991-07-05 | 1994-03-29 | Research Triangle Institute | S-2-(substituted ethylamino)ethyl phosphorothioates |
| WO1997018819A1 (en) * | 1995-11-20 | 1997-05-29 | Sepracor, Inc. | Antineoplastic methods and compositions employing optically pure (-)-fotemustine |
| JP2000500495A (ja) * | 1995-11-20 | 2000-01-18 | セプラコール，インク． | （＋）−フォテムスチンを用いる新生物を治療するための方法および組成物 |
| US20040072889A1 (en) * | 1997-04-21 | 2004-04-15 | Pharmacia Corporation | Method of using a COX-2 inhibitor and an alkylating-type antineoplastic agent as a combination therapy in the treatment of neoplasia |
| CN100365002C (zh) * | 2004-06-02 | 2008-01-30 | 上海医药科技发展有限公司 | 注射用福莫司汀制备工艺 |
| AT501496B1 (de) * | 2005-02-21 | 2007-03-15 | Iep Gmbh | Verfahren zur enantioselektiven enzymatischen reduktion von ketoverbindungen |
| CN102311456A (zh) * | 2011-07-08 | 2012-01-11 | 山东睿鹰先锋制药有限公司 | 一种福莫司汀原料药的合成方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3920733A (en) * | 1973-08-06 | 1975-11-18 | Monsanto Co | Ureidoalkylphosphonic acids |
-
1982
- 1982-11-17 FR FR8219199A patent/FR2536075B1/fr not_active Expired
-
1983
- 1983-11-02 US US06/547,881 patent/US4567169A/en not_active Expired - Lifetime
- 1983-11-15 PT PT77666A patent/PT77666B/pt unknown
- 1983-11-16 NZ NZ206293A patent/NZ206293A/en unknown
- 1983-11-16 MA MA20173A patent/MA19952A1/fr unknown
- 1983-11-16 AU AU21436/83A patent/AU557139B2/en not_active Expired
- 1983-11-16 EP EP83402209A patent/EP0117959B1/fr not_active Expired
- 1983-11-16 SU SU833665922A patent/SU1303024A3/ru active
- 1983-11-16 AT AT83402209T patent/ATE21905T1/de active
- 1983-11-16 IL IL70253A patent/IL70253A/xx not_active IP Right Cessation
- 1983-11-16 ZA ZA838558A patent/ZA838558B/xx unknown
- 1983-11-16 DK DK524283A patent/DK169340B1/da not_active IP Right Cessation
- 1983-11-16 IE IE2680/83A patent/IE56259B1/en not_active IP Right Cessation
- 1983-11-16 CA CA000441305A patent/CA1204442A/fr not_active Expired
- 1983-11-16 NO NO834214A patent/NO163409C/no unknown
- 1983-11-16 DE DE8383402209T patent/DE3365900D1/de not_active Expired
- 1983-11-17 JP JP58217066A patent/JPS59106497A/ja active Granted
- 1983-11-17 OA OA58159A patent/OA07589A/xx unknown
- 1983-11-17 ES ES527353A patent/ES8501772A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DK524283D0 (da) | 1983-11-16 |
| FR2536075A1 (fr) | 1984-05-18 |
| ES527353A0 (es) | 1984-12-01 |
| ES8501772A1 (es) | 1984-12-01 |
| PT77666B (fr) | 1986-05-12 |
| AU557139B2 (en) | 1986-12-04 |
| IE832680L (en) | 1984-05-17 |
| NO163409B (no) | 1990-02-12 |
| ATE21905T1 (de) | 1986-09-15 |
| DK524283A (da) | 1984-05-18 |
| ZA838558B (en) | 1984-07-25 |
| FR2536075B1 (fr) | 1985-07-05 |
| SU1303024A3 (ru) | 1987-04-07 |
| IL70253A (en) | 1986-10-31 |
| EP0117959B1 (fr) | 1986-09-03 |
| EP0117959A2 (fr) | 1984-09-12 |
| JPS59106497A (ja) | 1984-06-20 |
| CA1204442A (fr) | 1986-05-13 |
| IE56259B1 (en) | 1991-06-05 |
| AU2143683A (en) | 1984-05-24 |
| JPS6411637B2 (da) | 1989-02-27 |
| NO834214L (no) | 1984-05-18 |
| OA07589A (fr) | 1985-03-31 |
| MA19952A1 (fr) | 1984-07-01 |
| PT77666A (fr) | 1983-12-01 |
| DK169340B1 (da) | 1994-10-10 |
| IL70253A0 (en) | 1984-02-29 |
| NO163409C (no) | 1990-05-23 |
| DE3365900D1 (en) | 1986-10-09 |
| US4567169A (en) | 1986-01-28 |
| EP0117959A3 (en) | 1984-11-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ASS | Change of ownership |
Owner name: LES LABORATOIRES SERVIER, FR Free format text: OLD OWNER(S): ADIR |