DK524283A - Fremgangsmaade til fremstilling af nitrosoureaderivater - Google Patents

Fremgangsmaade til fremstilling af nitrosoureaderivater Download PDF

Info

Publication number
DK524283A
DK524283A DK524283A DK524283A DK524283A DK 524283 A DK524283 A DK 524283A DK 524283 A DK524283 A DK 524283A DK 524283 A DK524283 A DK 524283A DK 524283 A DK524283 A DK 524283A
Authority
DK
Denmark
Prior art keywords
alkyl
hydrogen
nitrosoure
additives
procedure
Prior art date
Application number
DK524283A
Other languages
English (en)
Other versions
DK524283D0 (da
DK169340B1 (da
Inventor
Gilbert Lavielle
Claude Cudennec
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Publication of DK524283D0 publication Critical patent/DK524283D0/da
Publication of DK524283A publication Critical patent/DK524283A/da
Application granted granted Critical
Publication of DK169340B1 publication Critical patent/DK169340B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
    • C07F9/3804—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se) not used, see subgroups
    • C07F9/3808—Acyclic saturated acids which can have further substituents on alkyl
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl
DK524283A 1982-11-17 1983-11-16 Analogifremgangsmåde til fremstilling af nitrosoureaderivater DK169340B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8219199A FR2536075B1 (fr) 1982-11-17 1982-11-17 Nouveaux derives de la nitrosouree, leur procede de preparation et les compositions pharmaceutiques les renfermant
FR8219199 1982-11-17

Publications (3)

Publication Number Publication Date
DK524283D0 DK524283D0 (da) 1983-11-16
DK524283A true DK524283A (da) 1984-05-18
DK169340B1 DK169340B1 (da) 1994-10-10

Family

ID=9279241

Family Applications (1)

Application Number Title Priority Date Filing Date
DK524283A DK169340B1 (da) 1982-11-17 1983-11-16 Analogifremgangsmåde til fremstilling af nitrosoureaderivater

Country Status (19)

Country Link
US (1) US4567169A (da)
EP (1) EP0117959B1 (da)
JP (1) JPS59106497A (da)
AT (1) ATE21905T1 (da)
AU (1) AU557139B2 (da)
CA (1) CA1204442A (da)
DE (1) DE3365900D1 (da)
DK (1) DK169340B1 (da)
ES (1) ES527353A0 (da)
FR (1) FR2536075B1 (da)
IE (1) IE56259B1 (da)
IL (1) IL70253A (da)
MA (1) MA19952A1 (da)
NO (1) NO163409C (da)
NZ (1) NZ206293A (da)
OA (1) OA07589A (da)
PT (1) PT77666B (da)
SU (1) SU1303024A3 (da)
ZA (1) ZA838558B (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2567129B1 (fr) * 1984-07-06 1986-12-05 Adir Nouveaux derives de l'oxaazaphosphorine, leur procede de preparation et les compositions pharmaceutiques les renfermant
IT1246778B (it) * 1991-04-12 1994-11-26 Boehringer Mannheim Italia Nitrosocarbamoil derivati di acidi gem-difosfonici, un processo per la loro preparazione e composizioni farmaceutiche che li contengono
US5298499A (en) * 1991-07-05 1994-03-29 Research Triangle Institute S-2-(substituted ethylamino)ethyl phosphorothioates
AU7737896A (en) * 1995-11-20 1997-06-11 Sepracor, Inc. Antineoplastic methods and compositions employing (+)-fotemustine
WO1997018819A1 (en) * 1995-11-20 1997-05-29 Sepracor, Inc. Antineoplastic methods and compositions employing optically pure (-)-fotemustine
US20040072889A1 (en) * 1997-04-21 2004-04-15 Pharmacia Corporation Method of using a COX-2 inhibitor and an alkylating-type antineoplastic agent as a combination therapy in the treatment of neoplasia
CN100365002C (zh) * 2004-06-02 2008-01-30 上海医药科技发展有限公司 注射用福莫司汀制备工艺
AT501496B1 (de) * 2005-02-21 2007-03-15 Iep Gmbh Verfahren zur enantioselektiven enzymatischen reduktion von ketoverbindungen
CN102311456A (zh) * 2011-07-08 2012-01-11 山东睿鹰先锋制药有限公司 一种福莫司汀原料药的合成方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3920733A (en) * 1973-08-06 1975-11-18 Monsanto Co Ureidoalkylphosphonic acids

Also Published As

Publication number Publication date
IL70253A0 (en) 1984-02-29
ES8501772A1 (es) 1984-12-01
NO834214L (no) 1984-05-18
EP0117959B1 (fr) 1986-09-03
AU2143683A (en) 1984-05-24
PT77666B (fr) 1986-05-12
IE56259B1 (en) 1991-06-05
NO163409B (no) 1990-02-12
OA07589A (fr) 1985-03-31
SU1303024A3 (ru) 1987-04-07
DK524283D0 (da) 1983-11-16
AU557139B2 (en) 1986-12-04
IL70253A (en) 1986-10-31
EP0117959A3 (en) 1984-11-14
PT77666A (fr) 1983-12-01
US4567169A (en) 1986-01-28
JPS6411637B2 (da) 1989-02-27
ZA838558B (en) 1984-07-25
CA1204442A (fr) 1986-05-13
EP0117959A2 (fr) 1984-09-12
DK169340B1 (da) 1994-10-10
ATE21905T1 (de) 1986-09-15
FR2536075A1 (fr) 1984-05-18
JPS59106497A (ja) 1984-06-20
ES527353A0 (es) 1984-12-01
IE832680L (en) 1984-05-17
NZ206293A (en) 1987-02-20
NO163409C (no) 1990-05-23
FR2536075B1 (fr) 1985-07-05
DE3365900D1 (en) 1986-10-09
MA19952A1 (fr) 1984-07-01

Similar Documents

Publication Publication Date Title
ES8705393A1 (es) Un procedimiento para preparar un derivado de pirazol (como divisional de la solicitud de patente de invencion n 543.046, presentada el 10.5.85)
FI802173A (fi) Terapeutiskt aktiva substituerade piperidiner och pyrrolidiner
ES525653A0 (es) Procedimiento para preparar nuevos diazabiciclo-(3.3.1)-nonanos
IT1179866B (it) Derivati del triptofano farmaceuticamente attivi e composizioni farmaceutiche che li contengono
DK524283A (da) Fremgangsmaade til fremstilling af nitrosoureaderivater
SE8802412L (sv) Tiokarbamidderivat
SE8105689L (sv) Terapeutiska medel
DK532679A (da) Fremgangsmaade til fremstilling af 2-aryl-3,4-diaza-bicyclo (4,1,0)hepten-(2)-on-(5).
ATE30152T1 (de) 1-methyl-5-nitro-imidazolin-derivate und diese enthaltende therapeutische zusammensetzungen.
ES543802A0 (es) Procedimiento de preparacion de nuevos derivados a-etilben- zol con un grupo n-carbamiloxi sustituido
DE3269505D1 (en) Substituted 1-benzoyl-2-phenylimino-imidazolidines, their acid addition salts, process for their preparation and pharmaceutical compositions containing them
ES8202003A1 (es) Un procedimiento para la preparacion de derivados de ergoli-na
FI834136A0 (fi) 1-aroyl-5-oxo-2-pyrrolidin-propansyror och mostvarande estrar
IL62599A (en) 3-benzyl-3-phenyltetrahydroimidazothiazol-3-ol and-thiazolopyrimidin-3-ol derivatives,their preparation and pharmaceutical compositions containing them
NO158805C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive (+)-cyanidan-3-ol-derivater.
DK602083A (da) 4-hydroxybenzhydroler
SE8105297L (sv) Imidazolderivat

Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PUP Patent expired