ZA838558B - Nitrosourea derivatives,process for the preparation thereof and pharmaceutical compositions containing them - Google Patents

Nitrosourea derivatives,process for the preparation thereof and pharmaceutical compositions containing them

Info

Publication number
ZA838558B
ZA838558B ZA838558A ZA838558A ZA838558B ZA 838558 B ZA838558 B ZA 838558B ZA 838558 A ZA838558 A ZA 838558A ZA 838558 A ZA838558 A ZA 838558A ZA 838558 B ZA838558 B ZA 838558B
Authority
ZA
South Africa
Prior art keywords
pharmaceutical compositions
preparation
compositions containing
alkyl
hydrogen
Prior art date
Application number
ZA838558A
Other languages
English (en)
Inventor
Gilbert Lavielle
Claude Cudennec
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Publication of ZA838558B publication Critical patent/ZA838558B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
    • C07F9/3804—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se) not used, see subgroups
    • C07F9/3808—Acyclic saturated acids which can have further substituents on alkyl
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl
ZA838558A 1982-11-17 1983-11-16 Nitrosourea derivatives,process for the preparation thereof and pharmaceutical compositions containing them ZA838558B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8219199A FR2536075B1 (fr) 1982-11-17 1982-11-17 Nouveaux derives de la nitrosouree, leur procede de preparation et les compositions pharmaceutiques les renfermant

Publications (1)

Publication Number Publication Date
ZA838558B true ZA838558B (en) 1984-07-25

Family

ID=9279241

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA838558A ZA838558B (en) 1982-11-17 1983-11-16 Nitrosourea derivatives,process for the preparation thereof and pharmaceutical compositions containing them

Country Status (19)

Country Link
US (1) US4567169A (xx)
EP (1) EP0117959B1 (xx)
JP (1) JPS59106497A (xx)
AT (1) ATE21905T1 (xx)
AU (1) AU557139B2 (xx)
CA (1) CA1204442A (xx)
DE (1) DE3365900D1 (xx)
DK (1) DK169340B1 (xx)
ES (1) ES527353A0 (xx)
FR (1) FR2536075B1 (xx)
IE (1) IE56259B1 (xx)
IL (1) IL70253A (xx)
MA (1) MA19952A1 (xx)
NO (1) NO163409C (xx)
NZ (1) NZ206293A (xx)
OA (1) OA07589A (xx)
PT (1) PT77666B (xx)
SU (1) SU1303024A3 (xx)
ZA (1) ZA838558B (xx)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2567129B1 (fr) * 1984-07-06 1986-12-05 Adir Nouveaux derives de l'oxaazaphosphorine, leur procede de preparation et les compositions pharmaceutiques les renfermant
IT1246778B (it) * 1991-04-12 1994-11-26 Boehringer Mannheim Italia Nitrosocarbamoil derivati di acidi gem-difosfonici, un processo per la loro preparazione e composizioni farmaceutiche che li contengono
US5298499A (en) * 1991-07-05 1994-03-29 Research Triangle Institute S-2-(substituted ethylamino)ethyl phosphorothioates
AU7737896A (en) * 1995-11-20 1997-06-11 Sepracor, Inc. Antineoplastic methods and compositions employing (+)-fotemustine
WO1997018819A1 (en) * 1995-11-20 1997-05-29 Sepracor, Inc. Antineoplastic methods and compositions employing optically pure (-)-fotemustine
US20040072889A1 (en) * 1997-04-21 2004-04-15 Pharmacia Corporation Method of using a COX-2 inhibitor and an alkylating-type antineoplastic agent as a combination therapy in the treatment of neoplasia
CN100365002C (zh) * 2004-06-02 2008-01-30 上海医药科技发展有限公司 注射用福莫司汀制备工艺
AT501496B1 (de) * 2005-02-21 2007-03-15 Iep Gmbh Verfahren zur enantioselektiven enzymatischen reduktion von ketoverbindungen
CN102311456A (zh) * 2011-07-08 2012-01-11 山东睿鹰先锋制药有限公司 一种福莫司汀原料药的合成方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3920733A (en) * 1973-08-06 1975-11-18 Monsanto Co Ureidoalkylphosphonic acids

Also Published As

Publication number Publication date
IL70253A0 (en) 1984-02-29
ES8501772A1 (es) 1984-12-01
NO834214L (no) 1984-05-18
EP0117959B1 (fr) 1986-09-03
AU2143683A (en) 1984-05-24
PT77666B (fr) 1986-05-12
IE56259B1 (en) 1991-06-05
NO163409B (no) 1990-02-12
OA07589A (fr) 1985-03-31
SU1303024A3 (ru) 1987-04-07
DK524283D0 (da) 1983-11-16
AU557139B2 (en) 1986-12-04
IL70253A (en) 1986-10-31
EP0117959A3 (en) 1984-11-14
PT77666A (fr) 1983-12-01
US4567169A (en) 1986-01-28
JPS6411637B2 (xx) 1989-02-27
CA1204442A (fr) 1986-05-13
EP0117959A2 (fr) 1984-09-12
DK524283A (da) 1984-05-18
DK169340B1 (da) 1994-10-10
ATE21905T1 (de) 1986-09-15
FR2536075A1 (fr) 1984-05-18
JPS59106497A (ja) 1984-06-20
ES527353A0 (es) 1984-12-01
IE832680L (en) 1984-05-17
NZ206293A (en) 1987-02-20
NO163409C (no) 1990-05-23
FR2536075B1 (fr) 1985-07-05
DE3365900D1 (en) 1986-10-09
MA19952A1 (fr) 1984-07-01

Similar Documents

Publication Publication Date Title
ES8705393A1 (es) Un procedimiento para preparar un derivado de pirazol (como divisional de la solicitud de patente de invencion n 543.046, presentada el 10.5.85)
IL65501A (en) 1-alkyl-2-aminotetralin derivatives,process for their preparation and pharmaceutical compositions containing them
DE3365900D1 (en) Nitrosourea derivatives, process for their preparation and pharmaceutical compositions containing them
DE2966809D1 (en) 3,4-diaza-bicyclo(4.1.0)hepten-2-ones-5, process for their preparation and therapeutical compositions containing them
ES8600224A1 (es) Procedimiento de preparacion de nuevos derivados carbamiloxibenzoles
DE3374005D1 (en) 1-methyl-5-nitro-imidazoline derivatives and therapeutic compositions which contain them as active principle
NZ220800A (en) Tetrahydrobenzothiazoles and pharmaceutical compositions
DE2962856D1 (en) Hexahydro-1,4-oxazepines, process for their preparation and pharmaceutical compositions containing them
ZA862891B (en) Triazole derivatives,a process for the preparation thereof and pharmaceutical compositions containing them
DE3362876D1 (en) Dibenzocycloheptenylidene compounds for use in modulating the immune response
IL62599A (en) 3-benzyl-3-phenyltetrahydroimidazothiazol-3-ol and-thiazolopyrimidin-3-ol derivatives,their preparation and pharmaceutical compositions containing them
DE3269505D1 (en) Substituted 1-benzoyl-2-phenylimino-imidazolidines, their acid addition salts, process for their preparation and pharmaceutical compositions containing them
ES477257A1 (es) Un procedimiento para preprarar derivados de isoquinoleina.
OA08056A (fr) Nouveaux dérivés de l'oxaazaphosphorine, leur procédé de préparation et les compositions pharmaceutiques les renfermant.
DE3463770D1 (en) Thieno(2,3-6)pyrrole derivatives, process for their preparation and pharmaceutical compositions containing them
ES485828A1 (es) Procedimiento para la preparacion de piridazinas substitui- das
ES8403471A1 (es) Un procedimiento para preparar nuevos compuestos de cromanona.