ES485828A1 - Procedimiento para la preparacion de piridazinas substitui- das - Google Patents

Procedimiento para la preparacion de piridazinas substitui- das

Info

Publication number
ES485828A1
ES485828A1 ES485828A ES485828A ES485828A1 ES 485828 A1 ES485828 A1 ES 485828A1 ES 485828 A ES485828 A ES 485828A ES 485828 A ES485828 A ES 485828A ES 485828 A1 ES485828 A1 ES 485828A1
Authority
ES
Spain
Prior art keywords
group
denotes
substituted
preparation
optionally
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES485828A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda GmbH
Original Assignee
Byk Gulden Lomberg Chemische Fabrik GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Byk Gulden Lomberg Chemische Fabrik GmbH filed Critical Byk Gulden Lomberg Chemische Fabrik GmbH
Publication of ES485828A1 publication Critical patent/ES485828A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/18—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Abstract

Procedimiento para la preparación de piridazinas sustituidas. Los compuestos preparados conforme al invento son utilizados en la industria farmacéutica para la preparación de medicamentes. La - hidrazino-ftalazina (hidralazina, su actividad hipotensora y los efectos secundarios , se describen compuestos derivados de hidralazina, a los cuales también se atribuyen propiedades antihipertentivas. Se ha sintetizado ahora una nueva clase de piridazinas sustituidas, que ni se menciona en las publicaciones mencionadas ni resulta evidente de ellas. Ademas se encontró que estas pirazinas sustituidas tienen propiedades farmacológicas interesantes, especialmente ventajosas.
ES485828A 1978-11-10 1979-11-08 Procedimiento para la preparacion de piridazinas substitui- das Expired ES485828A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1158578 1978-11-10

Publications (1)

Publication Number Publication Date
ES485828A1 true ES485828A1 (es) 1980-10-01

Family

ID=4374906

Family Applications (1)

Application Number Title Priority Date Filing Date
ES485828A Expired ES485828A1 (es) 1978-11-10 1979-11-08 Procedimiento para la preparacion de piridazinas substitui- das

Country Status (13)

Country Link
US (1) US4277472A (es)
EP (1) EP0011246A1 (es)
JP (1) JPS5566582A (es)
AU (1) AU5263379A (es)
DE (1) DE2945069A1 (es)
DK (1) DK467979A (es)
ES (1) ES485828A1 (es)
FI (1) FI793457A (es)
GB (1) GB2041351A (es)
GR (1) GR65640B (es)
IL (1) IL58640A0 (es)
PL (1) PL219471A1 (es)
PT (1) PT70428A (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2465132B (en) * 2007-09-21 2012-06-06 Lupin Ltd Compounds as dipeptidyl peptidase IV (DPP IV) inhibitors

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO136251C (no) * 1971-05-11 1977-08-10 Sandoz Ag Analogifremgangsm}te for fremstilling av terapeutisk aktive pyridazin-derivater.
US3954754A (en) * 1971-05-11 1976-05-04 Sandoz Ltd. 3-Hydrazino-cycloalkyl[c]pyridazines
DE2221808C2 (de) * 1972-05-04 1985-06-20 Sandoz-Patent-GmbH, 7850 Lörrach Hydrazinopyridazin-Derivate, deren Säureadditionssalze, Verfahren zu deren Herstellung und Heilmittel
FI224574A (es) 1973-08-02 1975-02-03 Sandoz Ag
US4181737A (en) * 1978-05-18 1980-01-01 The Dow Chemical Company 4-((3-Methoxyphenyl)amino)benzoic acid, a method for treating hyperlipidemia, and compositions thereof
US4179524A (en) * 1978-06-16 1979-12-18 Burroughs Wellcome Co. Biologically active amide
US4179506A (en) * 1978-11-13 1979-12-18 Warner-Lambert Company New pyridobenzodioxin compounds and methods for their production

Also Published As

Publication number Publication date
DE2945069A1 (de) 1980-05-22
GB2041351A (en) 1980-09-10
EP0011246A1 (de) 1980-05-28
PL219471A1 (es) 1980-12-01
GR65640B (en) 1980-10-15
US4277472A (en) 1981-07-07
FI793457A (fi) 1980-05-11
AU5263379A (en) 1980-05-15
IL58640A0 (en) 1980-02-29
JPS5566582A (en) 1980-05-20
DK467979A (da) 1980-05-11
PT70428A (de) 1979-12-01

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