IL70253A - N-nitrosourea phosphoric acid derivatives,their preparation and pharmaceutical compositions containing them - Google Patents

N-nitrosourea phosphoric acid derivatives,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL70253A
IL70253A IL70253A IL7025383A IL70253A IL 70253 A IL70253 A IL 70253A IL 70253 A IL70253 A IL 70253A IL 7025383 A IL7025383 A IL 7025383A IL 70253 A IL70253 A IL 70253A
Authority
IL
Israel
Prior art keywords
pharmaceutical compositions
nitrosourea
preparation
phosphoric acid
compositions containing
Prior art date
Application number
IL70253A
Other languages
English (en)
Other versions
IL70253A0 (en
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Publication of IL70253A0 publication Critical patent/IL70253A0/xx
Publication of IL70253A publication Critical patent/IL70253A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
    • C07F9/3804—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se) not used, see subgroups
    • C07F9/3808—Acyclic saturated acids which can have further substituents on alkyl
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl
IL70253A 1982-11-17 1983-11-16 N-nitrosourea phosphoric acid derivatives,their preparation and pharmaceutical compositions containing them IL70253A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8219199A FR2536075B1 (fr) 1982-11-17 1982-11-17 Nouveaux derives de la nitrosouree, leur procede de preparation et les compositions pharmaceutiques les renfermant

Publications (2)

Publication Number Publication Date
IL70253A0 IL70253A0 (en) 1984-02-29
IL70253A true IL70253A (en) 1986-10-31

Family

ID=9279241

Family Applications (1)

Application Number Title Priority Date Filing Date
IL70253A IL70253A (en) 1982-11-17 1983-11-16 N-nitrosourea phosphoric acid derivatives,their preparation and pharmaceutical compositions containing them

Country Status (19)

Country Link
US (1) US4567169A (da)
EP (1) EP0117959B1 (da)
JP (1) JPS59106497A (da)
AT (1) ATE21905T1 (da)
AU (1) AU557139B2 (da)
CA (1) CA1204442A (da)
DE (1) DE3365900D1 (da)
DK (1) DK169340B1 (da)
ES (1) ES8501772A1 (da)
FR (1) FR2536075B1 (da)
IE (1) IE56259B1 (da)
IL (1) IL70253A (da)
MA (1) MA19952A1 (da)
NO (1) NO163409C (da)
NZ (1) NZ206293A (da)
OA (1) OA07589A (da)
PT (1) PT77666B (da)
SU (1) SU1303024A3 (da)
ZA (1) ZA838558B (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2567129B1 (fr) * 1984-07-06 1986-12-05 Adir Nouveaux derives de l'oxaazaphosphorine, leur procede de preparation et les compositions pharmaceutiques les renfermant
IT1246778B (it) * 1991-04-12 1994-11-26 Boehringer Mannheim Italia Nitrosocarbamoil derivati di acidi gem-difosfonici, un processo per la loro preparazione e composizioni farmaceutiche che li contengono
US5298499A (en) * 1991-07-05 1994-03-29 Research Triangle Institute S-2-(substituted ethylamino)ethyl phosphorothioates
WO1997018819A1 (en) * 1995-11-20 1997-05-29 Sepracor, Inc. Antineoplastic methods and compositions employing optically pure (-)-fotemustine
JP2000500495A (ja) * 1995-11-20 2000-01-18 セプラコール，インク． （＋）−フォテムスチンを用いる新生物を治療するための方法および組成物
US20040072889A1 (en) * 1997-04-21 2004-04-15 Pharmacia Corporation Method of using a COX-2 inhibitor and an alkylating-type antineoplastic agent as a combination therapy in the treatment of neoplasia
CN100365002C (zh) * 2004-06-02 2008-01-30 上海医药科技发展有限公司 注射用福莫司汀制备工艺
AT501496B1 (de) * 2005-02-21 2007-03-15 Iep Gmbh Verfahren zur enantioselektiven enzymatischen reduktion von ketoverbindungen
CN102311456A (zh) * 2011-07-08 2012-01-11 山东睿鹰先锋制药有限公司 一种福莫司汀原料药的合成方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3920733A (en) * 1973-08-06 1975-11-18 Monsanto Co Ureidoalkylphosphonic acids

Also Published As

Publication number Publication date
DK524283D0 (da) 1983-11-16
FR2536075A1 (fr) 1984-05-18
ES527353A0 (es) 1984-12-01
ES8501772A1 (es) 1984-12-01
PT77666B (fr) 1986-05-12
AU557139B2 (en) 1986-12-04
IE832680L (en) 1984-05-17
NO163409B (no) 1990-02-12
ATE21905T1 (de) 1986-09-15
DK524283A (da) 1984-05-18
ZA838558B (en) 1984-07-25
NZ206293A (en) 1987-02-20
FR2536075B1 (fr) 1985-07-05
SU1303024A3 (ru) 1987-04-07
EP0117959B1 (fr) 1986-09-03
EP0117959A2 (fr) 1984-09-12
JPS59106497A (ja) 1984-06-20
CA1204442A (fr) 1986-05-13
IE56259B1 (en) 1991-06-05
AU2143683A (en) 1984-05-24
JPS6411637B2 (da) 1989-02-27
NO834214L (no) 1984-05-18
OA07589A (fr) 1985-03-31
MA19952A1 (fr) 1984-07-01
PT77666A (fr) 1983-12-01
DK169340B1 (da) 1994-10-10
IL70253A0 (en) 1984-02-29
NO163409C (no) 1990-05-23
DE3365900D1 (en) 1986-10-09
US4567169A (en) 1986-01-28
EP0117959A3 (en) 1984-11-14

Similar Documents

Publication Publication Date Title
IL82084A0 (en) 1,4-diazepines,their preparation and pharmaceutical compositions containing them
IL70253A (en) N-nitrosourea phosphoric acid derivatives,their preparation and pharmaceutical compositions containing them
ATE41772T1 (de) Polymethoxybenzyl-piperazin-derivate, verfahren zu ihrer herstellung und diese derivate enthaltende pharmazeutische zusammensetzungen.
EP0271013A3 (en) Basic substituted phenyl acetonitriles, their preparation and medicaments containing them
GR78771B (da)
DE3374005D1 (en) 1-methyl-5-nitro-imidazoline derivatives and therapeutic compositions which contain them as active principle
ES8600224A1 (es) Procedimiento de preparacion de nuevos derivados carbamiloxibenzoles
DE3660764D1 (en) Triazole derivatives, process for their preparation and pharmaceutical compositions containing them
ES487631A1 (es) Procedimiento para la obtencion de hexahidro-1,4-oxazepinas
ES435361A1 (es) Un metodo para la preparacion de nuevos esteres alcohilicosde aminoacidos.
ATE29251T1 (de) Aminopyridincarbonsaeure-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen.
SE8400629L (sv) Basiska oximetrar
ES477257A1 (es) Un procedimiento para preprarar derivados de isoquinoleina.
HUT34942A (en) Process for the production of new 4-hydroxy -benzhydrols, as well as of therapeutic preparations contaning them
DE3361670D1 (en) N-substituted imidazole derivatives, their preparation, pharmaceutical compositions containing them and their use
ES8201152A1 (es) Procedimiento para la preparacion de acidos 5-sulfamoilorta-nilicos
ES485828A1 (es) Procedimiento para la preparacion de piridazinas substitui- das

Legal Events

Date Code Title Description
EXP Patent expired