NZ191589A - 5-((r)-1-hydroxy-2-((r)-(1-methyl-3-phenylpropyl)-amino)-ethyl)-salicylamide and derivatives; intermediates; pharmaceutical compositions - Google Patents
5-((r)-1-hydroxy-2-((r)-(1-methyl-3-phenylpropyl)-amino)-ethyl)-salicylamide and derivatives; intermediates; pharmaceutical compositionsInfo
- Publication number
- NZ191589A NZ191589A NZ191589A NZ19158979A NZ191589A NZ 191589 A NZ191589 A NZ 191589A NZ 191589 A NZ191589 A NZ 191589A NZ 19158979 A NZ19158979 A NZ 19158979A NZ 191589 A NZ191589 A NZ 191589A
- Authority
- NZ
- New Zealand
- Prior art keywords
- methyl
- protected
- phenylpropyl
- salicylamide
- optical isomer
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
- C07C233/65—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Ophthalmology & Optometry (AREA)
- Vascular Medicine (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Epidemiology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Epoxy Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US94451678A | 1978-09-20 | 1978-09-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ191589A true NZ191589A (en) | 1984-03-30 |
Family
ID=25481553
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ191589A NZ191589A (en) | 1978-09-20 | 1979-09-17 | 5-((r)-1-hydroxy-2-((r)-(1-methyl-3-phenylpropyl)-amino)-ethyl)-salicylamide and derivatives; intermediates; pharmaceutical compositions |
Country Status (27)
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4658060A (en) * | 1982-04-26 | 1987-04-14 | Schering Corporation | Preparation of (-)-5-(beta)-1-hydroxy-2-((beta)-1-methyl-3-phenylpropyl)aminoethyl) salicylamide |
| IT1194406B (it) * | 1983-09-27 | 1988-09-22 | Scharper S P A | Procedimento per la preparazione di 2-idrossi-5-01-idrossi-2-((4-fenil-2-butil)ammino) etil benzammide |
| HU190867B (en) * | 1984-01-20 | 1986-11-28 | Egyt Gyogyszervegyeszeti Gyar,Hu | Process for preparing 2-hydroxy-5-/1-hydroxy-2-/1-methyl-3-phenyl-propyl/-amino/ethyl/-benzamide and pharmaceutically acceptable salts thereof |
| US4788183A (en) * | 1987-11-30 | 1988-11-29 | Schering Corporation | Method for treatment of dyslipidemia in humans |
| US4879233A (en) * | 1989-02-10 | 1989-11-07 | Schering Corporation | Novel Aspergillus niveus microorganism used for the chiral reduction of carbonyl groups |
| US6031003A (en) * | 1991-08-23 | 2000-02-29 | Nps Pharmaceuticals, Inc. | Calcium receptor-active molecules |
| US5858684A (en) * | 1991-08-23 | 1999-01-12 | The Brigham And Women's Hospital, Inc. | Method of screening calcium receptor-active molecules |
| US6001884A (en) * | 1991-08-23 | 1999-12-14 | Nps Pharmaceuticals, Inc. | Calcium receptor-active molecules |
| US5688938A (en) * | 1991-08-23 | 1997-11-18 | The Brigham & Women's Hospital, Inc. | Calcium receptor-active molecules |
| US6313146B1 (en) | 1991-08-23 | 2001-11-06 | Nps Pharmaceuticals, Inc. | Calcium receptor-active molecules |
| US5763569A (en) * | 1991-08-23 | 1998-06-09 | The Brigham And Women's Hospital, Inc | Calcium receptor-active molecules |
| EP1296142B1 (en) * | 1991-08-23 | 2005-12-07 | Nps Pharmaceuticals, Inc. | Screening method for calcium receptor active molecules |
| US6011068A (en) * | 1991-08-23 | 2000-01-04 | Nps Pharmaceuticals, Inc. | Calcium receptor-active molecules |
| US5962314A (en) * | 1993-02-23 | 1999-10-05 | Nps Pharmaceuticals, Inc. | Calcium receptor-active molecules |
| DE122005000033I1 (de) | 1994-10-21 | 2005-09-29 | Nps Pharma Inc | Kalzium-Rezeptor aktive Verbindungen. |
| PT907631E (pt) * | 1996-05-01 | 2003-10-31 | Nps Pharma Inc | Compostos inorganicos activos como receptores de ioes |
| IT1313583B1 (it) | 1999-07-30 | 2002-09-09 | Chiesi Farma Spa | Derivati 2-amminotetralinici per la terapia del glaucoma. |
| EP1961735B1 (en) * | 2007-02-22 | 2009-11-18 | Indena S.P.A. | Process for the preparation of (2r,3s)-3-phenylisoserine methyl ester acetate salt |
| AU2011289407B2 (en) | 2010-08-11 | 2015-06-18 | Philadelphia Health & Education Corporation | Novel D3 dopamine receptor agonists to treat dyskinesia in Parkinson's disease |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1266058A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1969-07-08 | 1972-03-08 | ||
| US4012444A (en) * | 1969-07-08 | 1977-03-15 | Allen & Hanburys Limited | 5-[1-Hydroxy-2-(1-methyl-3-phenylpropyl)aminoethyl] salicylamide and physiologically acceptable acid addition salts thereof |
| GB1541933A (en) * | 1975-04-17 | 1979-03-14 | Scherico Ltd | Pharmaceutical compositions containing a diastereoisomer of a phenylalkylaminoethanol derivative |
-
1979
- 1979-09-13 ZA ZA00794872A patent/ZA794872B/xx unknown
- 1979-09-17 NZ NZ191589A patent/NZ191589A/en unknown
- 1979-09-17 DK DK387579A patent/DK387579A/da not_active Application Discontinuation
- 1979-09-17 AT AT79103473T patent/ATE351T1/de not_active IP Right Cessation
- 1979-09-17 PH PH23042A patent/PH16794A/en unknown
- 1979-09-17 CY CY1175A patent/CY1175A/xx unknown
- 1979-09-17 FI FI792884A patent/FI792884A7/fi not_active Application Discontinuation
- 1979-09-17 EP EP79103473A patent/EP0009702B1/en not_active Expired
- 1979-09-17 DE DE7979103473T patent/DE2961263D1/de not_active Expired
- 1979-09-17 AU AU50881/79A patent/AU528626B2/en not_active Ceased
- 1979-09-17 NO NO792993A patent/NO149660C/no unknown
- 1979-09-18 OA OA56898A patent/OA06339A/xx unknown
- 1979-09-18 CA CA000335885A patent/CA1151211A/en not_active Expired
- 1979-09-18 IL IL58258A patent/IL58258A/xx unknown
- 1979-09-18 KR KR1019790003218A patent/KR830000904A/ko not_active Ceased
- 1979-09-18 IE IE1770/79A patent/IE49301B1/en unknown
- 1979-09-18 YU YU02273/79A patent/YU227379A/xx unknown
- 1979-09-18 GR GR60059A patent/GR73179B/el unknown
- 1979-09-18 JP JP11996879A patent/JPS5555147A/ja active Granted
- 1979-09-18 PT PT70191A patent/PT70191A/pt unknown
- 1979-09-19 DD DD79215640A patent/DD150457A5/de unknown
- 1979-09-19 HU HU79SCHE690A patent/HU185523B/hu unknown
- 1979-09-19 PL PL1979218408A patent/PL129114B1/pl unknown
-
1983
- 1983-01-04 SG SG2/83A patent/SG283G/en unknown
- 1983-04-21 HK HK133/83A patent/HK13383A/xx unknown
- 1983-04-25 KE KE3283A patent/KE3283A/xx unknown
- 1983-11-17 JP JP58217073A patent/JPS59108749A/ja active Pending
-
1984
- 1984-04-09 KR KR1019840001867A patent/KR890001998B1/ko not_active Expired
-
1985
- 1985-12-30 MY MY42/85A patent/MY8500042A/xx unknown
-
1989
- 1989-11-13 JP JP1292552A patent/JPH02167253A/ja active Pending
Also Published As
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