NO995687D0 - Fremgangsmåte for fremstilling av dispergerbare sterol- og stanol-forbindelser - Google Patents
Fremgangsmåte for fremstilling av dispergerbare sterol- og stanol-forbindelserInfo
- Publication number
- NO995687D0 NO995687D0 NO995687A NO995687A NO995687D0 NO 995687 D0 NO995687 D0 NO 995687D0 NO 995687 A NO995687 A NO 995687A NO 995687 A NO995687 A NO 995687A NO 995687 D0 NO995687 D0 NO 995687D0
- Authority
- NO
- Norway
- Prior art keywords
- sterol
- stanol
- preparation
- compounds
- preparing
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/200,623 US6242001B1 (en) | 1998-11-30 | 1998-11-30 | Method for producing dispersible sterol and stanol compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
NO995687D0 true NO995687D0 (no) | 1999-11-19 |
NO995687L NO995687L (no) | 2000-05-31 |
Family
ID=22742487
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO995687A NO995687L (no) | 1998-11-30 | 1999-11-19 | FremgangsmÕte for fremstilling av dispergerbare sterol- og stanol-forbindelser |
Country Status (9)
Country | Link |
---|---|
US (2) | US6242001B1 (no) |
EP (1) | EP1005859B1 (no) |
JP (1) | JP2000191684A (no) |
AT (1) | ATE315381T1 (no) |
CA (1) | CA2290315C (no) |
DE (1) | DE69929411T2 (no) |
DK (1) | DK1005859T3 (no) |
ES (1) | ES2257011T3 (no) |
NO (1) | NO995687L (no) |
Families Citing this family (41)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6376481B2 (en) * | 1998-09-02 | 2002-04-23 | Mcneil-Ppc, Inc. | Sterol esters in tableted solid dosage forms |
US6242001B1 (en) * | 1998-11-30 | 2001-06-05 | Mcneil-Ppc, Inc. | Method for producing dispersible sterol and stanol compounds |
DE50011218D1 (de) * | 1999-06-25 | 2005-10-27 | Cognis Ip Man Gmbh | Verwendung von nanoskaligen sterolen und sterolestern |
JP2003512850A (ja) * | 1999-11-03 | 2003-04-08 | フォーブス メディ−テック インコーポレーテッド | 食用油または脂肪と、その中に実質的に溶解したフィトステロールおよび/またはフィロスタノールとを含む組成物、その製造方法、並びに心血管疾患およびその根底にある状態を治療または予防することにおけるその使用 |
US6391370B1 (en) * | 1999-11-12 | 2002-05-21 | Kraft Foods, Inc. | Micromilling plant sterols and emulsifiers |
EP1274319B1 (en) | 2000-04-14 | 2009-08-12 | Mars, Incorporated | Compositions and methods for improving vascular health |
KR20020026053A (ko) * | 2000-09-30 | 2002-04-06 | 노승권 | 음료용 식물성 스테롤의 분산방법 및 이를 함유하는 음료 |
US6576285B1 (en) * | 2000-11-14 | 2003-06-10 | Sunpure Ltd. | Cholesterol lowering beverage |
US20020107232A1 (en) * | 2001-01-12 | 2002-08-08 | Flickinger Brent D. | Methods for producing sterol ester-rich compositions |
BR0205721A (pt) * | 2001-07-06 | 2003-09-30 | Endo Pharmaceuticals Inc | Formulações de oximorfona de liberação controlada |
US7012297B2 (en) * | 2001-08-30 | 2006-03-14 | Micron Technology, Inc. | Scalable flash/NV structures and devices with extended endurance |
US7144595B2 (en) * | 2001-11-16 | 2006-12-05 | Brandeis University | Prepared foods containing triglyceride-recrystallized non-esterified phytosterols |
US7763663B2 (en) * | 2001-12-19 | 2010-07-27 | University Of Massachusetts | Polysaccharide-containing block copolymer particles and uses thereof |
AU2002241368B2 (en) * | 2002-03-20 | 2009-07-09 | Eugene Science Inc. | Plant sterol-containing food, and method for preparing the same |
CN1297216C (zh) * | 2002-03-20 | 2007-01-31 | 尤金科学(有限)公司 | 植物甾醇与乳化剂的混合粉末及其制备方法 |
US6623780B1 (en) | 2002-03-26 | 2003-09-23 | Cargill, Inc. | Aqueous dispersible sterol product |
AU2003230878A1 (en) * | 2002-04-10 | 2003-10-27 | Cargill, Incorporated | Aqueous dispersible steryl ester compositions |
US20030212046A1 (en) * | 2002-05-07 | 2003-11-13 | Kapac, Llc | Methods and formulations for enhancing the absorption and gastro-intestinal bioavailability of hydrophobic drugs |
US20060093661A1 (en) | 2002-05-07 | 2006-05-04 | Kapac, Llc | Methods and formulations for enhancing the absorption and gastro-intestinal bioavailability of hydrophobic drugs |
US7306819B2 (en) * | 2002-06-12 | 2007-12-11 | The Coca-Cola Company | Beverages containing plant sterols |
RU2329734C2 (ru) * | 2002-06-12 | 2008-07-27 | Дзе Кока-Кола Компани | Способ получения дисперсии, напиток и композиция |
IS6633A (is) * | 2002-11-22 | 2004-05-23 | Omega Farma Ehf. | Samsetningar af fínasteríð töflum |
US20060182820A1 (en) * | 2004-02-10 | 2006-08-17 | Cargill, Incorporated | Homogeneous Dispersions Containing Citrus Pulp and Applications Thereof |
US20050175672A1 (en) * | 2004-02-10 | 2005-08-11 | Kluetz Michael D. | Particulate plant sterol compositions |
EP1791578A2 (en) * | 2004-02-26 | 2007-06-06 | Tasker Products IP Holdings Corp. | Antimicrobial composition for pre-harvest and post-harvest treatment of plants and animals |
US20080213444A1 (en) * | 2004-02-26 | 2008-09-04 | Tasker Products, Inc. | Compositions and methods for reducing microbial contamination in meat processing |
CN103315954A (zh) | 2005-07-18 | 2013-09-25 | 麻萨诸塞州洛厄尔大学 | 制备与使用纳米乳剂的组合物和方法 |
KR20080055956A (ko) * | 2005-09-29 | 2008-06-19 | 레프로스 쎄라피우틱스 아이엔씨. | 향상된 생체이용률을 가지며, 스테로이드 유도체와폴리글리콜리세드 글리세리드를 포함하는 제제 |
US9486408B2 (en) | 2005-12-01 | 2016-11-08 | University Of Massachusetts Lowell | Botulinum nanoemulsions |
BRPI0619134B8 (pt) | 2005-12-01 | 2021-05-25 | Univ Massachusetts Lowell | nanoemulsão, composição farmacêutica, composição, métodos cosméticos para o tratamento de rugas, linhas faciais e/ou linhas do pescoço, e de retardar o início das rugas, linhas faciais e/ou linhas do pescoço, e, método de fabricação de uma nanoemulsão |
WO2007067735A2 (en) * | 2005-12-08 | 2007-06-14 | Tasker Products Ip Holdings Corp. | Skin care composition for dermatological disorders |
WO2007101581A2 (de) * | 2006-03-08 | 2007-09-13 | Cognis Ip Management Gmbh | Sterolhaltige pulver |
US20080124387A1 (en) | 2006-11-27 | 2008-05-29 | Kapac, Llc | Methods and formulations for enhancing the absorption and decreasing the absorption variability of orally administered drugs, vitamins and nutrients |
AU2007329579A1 (en) | 2006-12-01 | 2008-06-12 | Anterios, Inc. | Amphiphilic entity nanoparticles |
AU2007353340A1 (en) | 2006-12-01 | 2008-11-20 | Anterios, Inc. | Peptide nanoparticles and uses therefor |
CN103961315A (zh) | 2007-05-31 | 2014-08-06 | 安特里奥公司 | 核酸纳米粒子和其用途 |
US20090088393A1 (en) * | 2007-09-28 | 2009-04-02 | Zomanex, Llc | Methods and formulations for converting intravenous and injectable drugs into oral dosage forms |
US20090092727A1 (en) * | 2007-10-04 | 2009-04-09 | Daniel Perlman | Water-dispersible phytosterol-surfactant conglomerate particles |
BRPI0914630A2 (pt) * | 2008-06-26 | 2019-09-24 | Anterios Inc | liberação dérmica |
US20110223312A1 (en) * | 2009-11-30 | 2011-09-15 | Daniel Perlman | Triglyceride-encapsulated phytosterol microparticles dispersed in beverages |
AU2017360346B2 (en) | 2016-11-21 | 2023-11-23 | Eirion Therapeutics, Inc. | Transdermal delivery of large agents |
Family Cites Families (42)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3085939A (en) | 1959-05-11 | 1963-04-16 | Upjohn Co | Oil-in-water emulsion for oral administration, and process for preparation |
US3004043A (en) | 1959-10-09 | 1961-10-10 | Eastman Kodak Co | Water-soluble vegetable oil sterol derivatives |
CA928140A (en) | 1969-07-17 | 1973-06-12 | A. Erickson Billy | Clear cooking and salad oils having hypocholesterolemic properties |
US3865939A (en) | 1973-02-23 | 1975-02-11 | Procter & Gamble | Edible oils having hypocholesterolemic properties |
US3881005A (en) | 1973-08-13 | 1975-04-29 | Lilly Co Eli | Pharmaceutical dispersible powder of sitosterols and a method for the preparation thereof |
US4391732A (en) | 1975-06-06 | 1983-07-05 | Henkel Corporation | Phytosterol blends |
US4005196A (en) | 1976-02-12 | 1977-01-25 | The Procter & Gamble Company | Vitaminized compositions for treating hypercholesterolemia |
US4195084A (en) | 1977-01-07 | 1980-03-25 | Eli Lilly And Company | Taste-stable aqueous pharmaceutical suspension of tall oil sitosterols and a method for the preparation thereof |
US4423041A (en) | 1979-06-25 | 1983-12-27 | Johnson & Johnson Products, Inc. | Detackifying compositions |
EP0053415B1 (en) | 1980-12-02 | 1985-10-09 | Duphar International Research B.V | Method of isolating sterols in commercial quantities from sterol-containing material |
FI63423C (fi) | 1981-01-27 | 1983-06-10 | Farmos Oy | Foerfarande foer separering av beta-sitosterol fraon en sterolblandning utvunnen ur raosaopans neutralfraktion |
EP0179583A1 (en) | 1984-10-04 | 1986-04-30 | Merck & Co. Inc. | A system for enhancing the water dissolution rate and solubility of poorly soluble drugs |
US5219733A (en) | 1985-03-06 | 1993-06-15 | Yoshikawa Oil & Fat Co., Ltd. | Process for preparing fatty acid esters |
JPS62186936A (ja) | 1986-02-13 | 1987-08-15 | Asahi Denka Kogyo Kk | ステリン乳化乃至可溶化組成物 |
DE3829643A1 (de) | 1988-09-01 | 1990-03-15 | Roecar Holdings Nv | Phyto- und zoosterole und deren derivate mit verbesserter wasserloeslichkeit |
DE59004337D1 (de) | 1989-07-21 | 1994-03-03 | Marigen Sa | Sterole, deren fettsäureester und glucoside; verfahren zu ihrer herstellung; spontan dispergierbare mittel mit diesen verbindungen, sowie ihre verwendung zur behandlung von tumoren. |
US5723747A (en) | 1991-02-22 | 1998-03-03 | Calgene, Inc. | Wax esters in transformed plants |
DE69127207T2 (de) | 1991-05-03 | 1998-01-22 | Raision Tehtaat Oy Ab | Substanz zur absenkung eines hohen cholesterolspiegels im serum und verfahren zu ihrer herstellung |
IL102633A0 (en) * | 1991-07-26 | 1993-01-14 | Smithkline Beecham Corp | Compositions |
US5244887A (en) | 1992-02-14 | 1993-09-14 | Straub Carl D | Stanols to reduce cholesterol absorption from foods and methods of preparation and use thereof |
JPH06329588A (ja) * | 1993-05-19 | 1994-11-29 | Riken Vitamin Co Ltd | 水分散性モノグリセリド |
AU676315B2 (en) | 1993-06-30 | 1997-03-06 | Takeda Chemical Industries Ltd. | Stabilized solid pharmaceutical preparation and method of producing the same |
AU3559795A (en) | 1994-09-29 | 1996-04-19 | University Of British Columbia, The | Sterol compositions from pulping soap |
US5492714A (en) | 1994-11-08 | 1996-02-20 | The Procter & Gamble Company | Reduced calorie fats which comprise reduced calorie triglycerides containing medium and long chain fatty acids and which exhibit rapid crystallization to beta phase |
US5486318A (en) | 1994-12-29 | 1996-01-23 | The Boc Group, Inc. | Liquid-vapor contact column |
US5578334A (en) | 1995-04-07 | 1996-11-26 | Brandeis University | Increasing the HDL level and the HDL/LDL ratio in human serum with fat blends |
BR9608914A (pt) | 1995-06-01 | 1999-03-02 | Unilever Nv | Produto alimentício á base de gorgura pasta de gordura amarela e uso de um concentrado oleoso |
US5698527A (en) | 1995-08-08 | 1997-12-16 | Merck & Co., Inc. | Steroidal glycosides as antihyperlipidemic agents |
GB9613858D0 (en) * | 1996-07-02 | 1996-09-04 | Cortecs Ltd | Hydrophobic preparations |
US6139872A (en) | 1996-08-14 | 2000-10-31 | Henkel Corporation | Method of producing a vitamin product |
US6383514B1 (en) * | 1996-11-28 | 2002-05-07 | Henkel Kommanditgesellschaft Auf Aktien | Use of mixtures of active substances for the production of hypocholesterolemic agents |
US5837714A (en) | 1997-03-03 | 1998-11-17 | Sanofi | Solid pharmaceutical dispersions |
ES2231940T3 (es) | 1997-08-22 | 2005-05-16 | Unilever N.V. | Composicion de esteres de estanol. |
WO1999018977A1 (en) | 1997-10-16 | 1999-04-22 | Medical Isotopes Inc. | Readily absorbable phytosterol glycosides to treat hypercholesterolemia |
US6025010A (en) | 1997-11-21 | 2000-02-15 | Lipton, Division Of Conopco, Inc. | Multifunctional spread |
US6045853A (en) | 1997-12-05 | 2000-04-04 | Lipton, Division Of Conopco, Inc. | Fat continuous spread and process for making the same |
US6110502A (en) | 1998-02-19 | 2000-08-29 | Mcneil-Ppc, Inc. | Method for producing water dispersible sterol formulations |
US6025348A (en) | 1998-04-30 | 2000-02-15 | Kao Corporation | Oil and fat composition containing phytosterol |
SE512958C2 (sv) | 1998-04-30 | 2000-06-12 | Triple Crown Ab | Kolesterolsänkande komposition innehållande beta-sitosterol och/eller beta-sitostanol samt förfarande för dess framställning |
US5932562A (en) | 1998-05-26 | 1999-08-03 | Washington University | Sitostanol formulation to reduce cholesterol absorption and method for preparing and use of same |
EP1082026A1 (en) | 1998-06-05 | 2001-03-14 | Forbes Medi-Tech Inc. | Compositions comprising phytosterol and/or phytostanol having enhenced solubility and dispersa |
US6242001B1 (en) * | 1998-11-30 | 2001-06-05 | Mcneil-Ppc, Inc. | Method for producing dispersible sterol and stanol compounds |
-
1998
- 1998-11-30 US US09/200,623 patent/US6242001B1/en not_active Expired - Lifetime
-
1999
- 1999-11-19 NO NO995687A patent/NO995687L/no not_active Application Discontinuation
- 1999-11-24 CA CA002290315A patent/CA2290315C/en not_active Expired - Fee Related
- 1999-11-29 DE DE69929411T patent/DE69929411T2/de not_active Expired - Lifetime
- 1999-11-29 JP JP11338407A patent/JP2000191684A/ja active Pending
- 1999-11-29 DK DK99309492T patent/DK1005859T3/da active
- 1999-11-29 AT AT99309492T patent/ATE315381T1/de active
- 1999-11-29 EP EP99309492A patent/EP1005859B1/en not_active Expired - Lifetime
- 1999-11-29 ES ES99309492T patent/ES2257011T3/es not_active Expired - Lifetime
-
2001
- 2001-04-04 US US09/826,072 patent/US6387411B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
ATE315381T1 (de) | 2006-02-15 |
DE69929411D1 (de) | 2006-04-06 |
CA2290315A1 (en) | 2000-05-30 |
CA2290315C (en) | 2008-11-18 |
NO995687L (no) | 2000-05-31 |
US6242001B1 (en) | 2001-06-05 |
DK1005859T3 (da) | 2006-04-03 |
ES2257011T3 (es) | 2006-07-16 |
US20010012521A1 (en) | 2001-08-09 |
DE69929411T2 (de) | 2006-08-24 |
JP2000191684A (ja) | 2000-07-11 |
EP1005859A1 (en) | 2000-06-07 |
US6387411B2 (en) | 2002-05-14 |
EP1005859B1 (en) | 2006-01-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |