NO995687D0 - Fremgangsmåte for fremstilling av dispergerbare sterol- og stanol-forbindelser - Google Patents
Fremgangsmåte for fremstilling av dispergerbare sterol- og stanol-forbindelserInfo
- Publication number
- NO995687D0 NO995687D0 NO995687A NO995687A NO995687D0 NO 995687 D0 NO995687 D0 NO 995687D0 NO 995687 A NO995687 A NO 995687A NO 995687 A NO995687 A NO 995687A NO 995687 D0 NO995687 D0 NO 995687D0
- Authority
- NO
- Norway
- Prior art keywords
- sterol
- stanol
- preparation
- compounds
- preparing
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/200,623 US6242001B1 (en) | 1998-11-30 | 1998-11-30 | Method for producing dispersible sterol and stanol compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
NO995687D0 true NO995687D0 (no) | 1999-11-19 |
NO995687L NO995687L (no) | 2000-05-31 |
Family
ID=22742487
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO995687A NO995687L (no) | 1998-11-30 | 1999-11-19 | FremgangsmÕte for fremstilling av dispergerbare sterol- og stanol-forbindelser |
Country Status (9)
Country | Link |
---|---|
US (2) | US6242001B1 (no) |
EP (1) | EP1005859B1 (no) |
JP (1) | JP2000191684A (no) |
AT (1) | ATE315381T1 (no) |
CA (1) | CA2290315C (no) |
DE (1) | DE69929411T2 (no) |
DK (1) | DK1005859T3 (no) |
ES (1) | ES2257011T3 (no) |
NO (1) | NO995687L (no) |
Families Citing this family (41)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6376481B2 (en) * | 1998-09-02 | 2002-04-23 | Mcneil-Ppc, Inc. | Sterol esters in tableted solid dosage forms |
US6242001B1 (en) * | 1998-11-30 | 2001-06-05 | Mcneil-Ppc, Inc. | Method for producing dispersible sterol and stanol compounds |
JP2003516115A (ja) * | 1999-06-25 | 2003-05-13 | コグニス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | ナノスケールステロールおよびステロールエステルの使用 |
DE60017443T2 (de) * | 1999-11-03 | 2005-06-09 | Forbes Medi-Tech Inc., Vancouver | Zusammensetzungen mit essbaren ölen oder fetten und darin aufgelösten phytosterolen und/oder phytostanolen |
US6391370B1 (en) * | 1999-11-12 | 2002-05-21 | Kraft Foods, Inc. | Micromilling plant sterols and emulsifiers |
KR20030005280A (ko) | 2000-04-14 | 2003-01-17 | 마아즈, 인코오포레이티드 | 혈관의 건강을 개선하기 위한 조성물과 방법 |
KR20020026053A (ko) * | 2000-09-30 | 2002-04-06 | 노승권 | 음료용 식물성 스테롤의 분산방법 및 이를 함유하는 음료 |
US6576285B1 (en) * | 2000-11-14 | 2003-06-10 | Sunpure Ltd. | Cholesterol lowering beverage |
US20020107232A1 (en) * | 2001-01-12 | 2002-08-08 | Flickinger Brent D. | Methods for producing sterol ester-rich compositions |
CA2452871C (en) * | 2001-07-06 | 2011-10-04 | Endo Pharmaceuticals, Inc. | Oxymorphone controlled release formulations |
US7012297B2 (en) * | 2001-08-30 | 2006-03-14 | Micron Technology, Inc. | Scalable flash/NV structures and devices with extended endurance |
US7144595B2 (en) | 2001-11-16 | 2006-12-05 | Brandeis University | Prepared foods containing triglyceride-recrystallized non-esterified phytosterols |
US7763663B2 (en) * | 2001-12-19 | 2010-07-27 | University Of Massachusetts | Polysaccharide-containing block copolymer particles and uses thereof |
CN1297216C (zh) * | 2002-03-20 | 2007-01-31 | 尤金科学(有限)公司 | 植物甾醇与乳化剂的混合粉末及其制备方法 |
US20050170064A1 (en) * | 2002-03-20 | 2005-08-04 | Eugene Science Inc. | Plant sterol-containing food, and method for preparing the same |
US6623780B1 (en) | 2002-03-26 | 2003-09-23 | Cargill, Inc. | Aqueous dispersible sterol product |
JP2005529109A (ja) * | 2002-04-10 | 2005-09-29 | カーギル,インコーポレイティド | 水性分散性ステリル・エステル組成物 |
US20030212046A1 (en) * | 2002-05-07 | 2003-11-13 | Kapac, Llc | Methods and formulations for enhancing the absorption and gastro-intestinal bioavailability of hydrophobic drugs |
US20060093661A1 (en) | 2002-05-07 | 2006-05-04 | Kapac, Llc | Methods and formulations for enhancing the absorption and gastro-intestinal bioavailability of hydrophobic drugs |
US7306819B2 (en) * | 2002-06-12 | 2007-12-11 | The Coca-Cola Company | Beverages containing plant sterols |
JP4773720B2 (ja) * | 2002-06-12 | 2011-09-14 | ザ・コカ−コーラ・カンパニー | 植物ステロール含有飲料 |
IS6633A (is) * | 2002-11-22 | 2004-05-23 | Omega Farma Ehf. | Samsetningar af fínasteríð töflum |
US20060182820A1 (en) * | 2004-02-10 | 2006-08-17 | Cargill, Incorporated | Homogeneous Dispersions Containing Citrus Pulp and Applications Thereof |
US20050175672A1 (en) * | 2004-02-10 | 2005-08-11 | Kluetz Michael D. | Particulate plant sterol compositions |
US20080213444A1 (en) * | 2004-02-26 | 2008-09-04 | Tasker Products, Inc. | Compositions and methods for reducing microbial contamination in meat processing |
US7192618B2 (en) * | 2004-02-26 | 2007-03-20 | Tasker Products Ip Holdings Corp. | Antimicrobial composition for pre-harvest and post-harvest treatment of plants and animals |
KR101430767B1 (ko) | 2005-07-18 | 2014-08-19 | 유니버시티 오브 메사츄세츠 로웰 | 나노에멀젼 조성물 및 이의 제조 및 사용 방법 |
AU2006294449A1 (en) * | 2005-09-29 | 2007-04-05 | Repros Therapeutics Inc. | Formulations with improved bioavailability, comprising a steroid derivative and a polyglycolysed glyceride |
ES2710781T3 (es) | 2005-12-01 | 2019-04-26 | Univ Massachusetts Lowell | Nanoemulsiones de botulinum |
US9486408B2 (en) | 2005-12-01 | 2016-11-08 | University Of Massachusetts Lowell | Botulinum nanoemulsions |
US20070190175A1 (en) * | 2005-12-08 | 2007-08-16 | Tasker Products Ip Holding Corp | Skin care composition for dermatological disorders |
JP5294881B2 (ja) * | 2006-03-08 | 2013-09-18 | コグニス・アイピー・マネージメント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | ステロール含有粉末 |
US20080124387A1 (en) | 2006-11-27 | 2008-05-29 | Kapac, Llc | Methods and formulations for enhancing the absorption and decreasing the absorption variability of orally administered drugs, vitamins and nutrients |
KR20150028308A (ko) | 2006-12-01 | 2015-03-13 | 안테리오스, 인코퍼레이티드 | 펩티드 나노입자 및 이의 용도 |
JP2010528981A (ja) | 2006-12-01 | 2010-08-26 | アンテリオス, インコーポレイテッド | 両親媒性実体ナノ粒子 |
CN101765423B (zh) | 2007-05-31 | 2014-08-06 | 安特里奥公司 | 核酸纳米粒子和其用途 |
US20090088393A1 (en) * | 2007-09-28 | 2009-04-02 | Zomanex, Llc | Methods and formulations for converting intravenous and injectable drugs into oral dosage forms |
US20090092727A1 (en) * | 2007-10-04 | 2009-04-09 | Daniel Perlman | Water-dispersible phytosterol-surfactant conglomerate particles |
BRPI0914630A2 (pt) * | 2008-06-26 | 2019-09-24 | Anterios Inc | liberação dérmica |
US20110223312A1 (en) * | 2009-11-30 | 2011-09-15 | Daniel Perlman | Triglyceride-encapsulated phytosterol microparticles dispersed in beverages |
WO2018093465A1 (en) | 2016-11-21 | 2018-05-24 | Eirion Therapeutics, Inc. | Transdermal delivery of large agents |
Family Cites Families (42)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3085939A (en) | 1959-05-11 | 1963-04-16 | Upjohn Co | Oil-in-water emulsion for oral administration, and process for preparation |
US3004043A (en) | 1959-10-09 | 1961-10-10 | Eastman Kodak Co | Water-soluble vegetable oil sterol derivatives |
CA928140A (en) | 1969-07-17 | 1973-06-12 | A. Erickson Billy | Clear cooking and salad oils having hypocholesterolemic properties |
US3865939A (en) | 1973-02-23 | 1975-02-11 | Procter & Gamble | Edible oils having hypocholesterolemic properties |
US3881005A (en) | 1973-08-13 | 1975-04-29 | Lilly Co Eli | Pharmaceutical dispersible powder of sitosterols and a method for the preparation thereof |
US4391732A (en) | 1975-06-06 | 1983-07-05 | Henkel Corporation | Phytosterol blends |
US4005196A (en) | 1976-02-12 | 1977-01-25 | The Procter & Gamble Company | Vitaminized compositions for treating hypercholesterolemia |
US4195084A (en) | 1977-01-07 | 1980-03-25 | Eli Lilly And Company | Taste-stable aqueous pharmaceutical suspension of tall oil sitosterols and a method for the preparation thereof |
US4423041A (en) | 1979-06-25 | 1983-12-27 | Johnson & Johnson Products, Inc. | Detackifying compositions |
EP0053415B1 (en) | 1980-12-02 | 1985-10-09 | Duphar International Research B.V | Method of isolating sterols in commercial quantities from sterol-containing material |
FI63423C (fi) | 1981-01-27 | 1983-06-10 | Farmos Oy | Foerfarande foer separering av beta-sitosterol fraon en sterolblandning utvunnen ur raosaopans neutralfraktion |
EP0179583A1 (en) | 1984-10-04 | 1986-04-30 | Merck & Co. Inc. | A system for enhancing the water dissolution rate and solubility of poorly soluble drugs |
US5219733A (en) | 1985-03-06 | 1993-06-15 | Yoshikawa Oil & Fat Co., Ltd. | Process for preparing fatty acid esters |
JPS62186936A (ja) | 1986-02-13 | 1987-08-15 | Asahi Denka Kogyo Kk | ステリン乳化乃至可溶化組成物 |
DE3829643A1 (de) | 1988-09-01 | 1990-03-15 | Roecar Holdings Nv | Phyto- und zoosterole und deren derivate mit verbesserter wasserloeslichkeit |
WO1991001139A1 (de) | 1989-07-21 | 1991-02-07 | Marigen S.A. | Sterole, deren fettsäureester und glucoside; verfahren zu ihrer herstellung; spontan dispergierbare mittel mit diesen verbindungen, sowie ihre verwendung zur behandlung von tumoren |
US5723747A (en) | 1991-02-22 | 1998-03-03 | Calgene, Inc. | Wax esters in transformed plants |
RU2095367C1 (ru) | 1991-05-03 | 1997-11-10 | Райсион Техтаат ой АБ | Вещество, понижающее уровень холестерина в сыворотке крови, и способ его получения |
WO1993002664A1 (en) * | 1991-07-26 | 1993-02-18 | Smithkline Beecham Corporation | W/o microemulsions |
US5244887A (en) | 1992-02-14 | 1993-09-14 | Straub Carl D | Stanols to reduce cholesterol absorption from foods and methods of preparation and use thereof |
JPH06329588A (ja) * | 1993-05-19 | 1994-11-29 | Riken Vitamin Co Ltd | 水分散性モノグリセリド |
AU676315B2 (en) | 1993-06-30 | 1997-03-06 | Takeda Chemical Industries Ltd. | Stabilized solid pharmaceutical preparation and method of producing the same |
EE9700073A (et) | 1994-09-29 | 1997-10-15 | The University Of British Columbia | Pulbiseebist saadavad steroolsed kompositsioonid |
US5492714A (en) | 1994-11-08 | 1996-02-20 | The Procter & Gamble Company | Reduced calorie fats which comprise reduced calorie triglycerides containing medium and long chain fatty acids and which exhibit rapid crystallization to beta phase |
US5486318A (en) | 1994-12-29 | 1996-01-23 | The Boc Group, Inc. | Liquid-vapor contact column |
US5578334A (en) | 1995-04-07 | 1996-11-26 | Brandeis University | Increasing the HDL level and the HDL/LDL ratio in human serum with fat blends |
ES2205701T3 (es) | 1995-06-01 | 2004-05-01 | Unilever N.V. | Productos alimenticios a base de grasas. |
US5698527A (en) | 1995-08-08 | 1997-12-16 | Merck & Co., Inc. | Steroidal glycosides as antihyperlipidemic agents |
GB9613858D0 (en) * | 1996-07-02 | 1996-09-04 | Cortecs Ltd | Hydrophobic preparations |
US6139872A (en) | 1996-08-14 | 2000-10-31 | Henkel Corporation | Method of producing a vitamin product |
EP0941097B1 (de) * | 1996-11-28 | 2002-05-02 | Cognis Deutschland GmbH & Co. KG | Verwendung von wirkstoffmischungen zur herstellung von hypocholesterinämischen mitteln |
US5837714A (en) | 1997-03-03 | 1998-11-17 | Sanofi | Solid pharmaceutical dispersions |
DE69827330T2 (de) | 1997-08-22 | 2006-02-02 | Unilever N.V. | Stanolester enthaltende Zusammensetzung |
WO1999018977A1 (en) | 1997-10-16 | 1999-04-22 | Medical Isotopes Inc. | Readily absorbable phytosterol glycosides to treat hypercholesterolemia |
US6025010A (en) | 1997-11-21 | 2000-02-15 | Lipton, Division Of Conopco, Inc. | Multifunctional spread |
US6045853A (en) | 1997-12-05 | 2000-04-04 | Lipton, Division Of Conopco, Inc. | Fat continuous spread and process for making the same |
US6110502A (en) | 1998-02-19 | 2000-08-29 | Mcneil-Ppc, Inc. | Method for producing water dispersible sterol formulations |
US6025348A (en) | 1998-04-30 | 2000-02-15 | Kao Corporation | Oil and fat composition containing phytosterol |
SE512958C2 (sv) | 1998-04-30 | 2000-06-12 | Triple Crown Ab | Kolesterolsänkande komposition innehållande beta-sitosterol och/eller beta-sitostanol samt förfarande för dess framställning |
US5932562A (en) | 1998-05-26 | 1999-08-03 | Washington University | Sitostanol formulation to reduce cholesterol absorption and method for preparing and use of same |
AU771960B2 (en) | 1998-06-05 | 2004-04-08 | Forbes Medi-Tech Inc. | Compositions comprising phytosterol and/or phytostanol having enhanced solubility and dispersability |
US6242001B1 (en) * | 1998-11-30 | 2001-06-05 | Mcneil-Ppc, Inc. | Method for producing dispersible sterol and stanol compounds |
-
1998
- 1998-11-30 US US09/200,623 patent/US6242001B1/en not_active Expired - Lifetime
-
1999
- 1999-11-19 NO NO995687A patent/NO995687L/no not_active Application Discontinuation
- 1999-11-24 CA CA002290315A patent/CA2290315C/en not_active Expired - Fee Related
- 1999-11-29 ES ES99309492T patent/ES2257011T3/es not_active Expired - Lifetime
- 1999-11-29 JP JP11338407A patent/JP2000191684A/ja active Pending
- 1999-11-29 DK DK99309492T patent/DK1005859T3/da active
- 1999-11-29 AT AT99309492T patent/ATE315381T1/de active
- 1999-11-29 EP EP99309492A patent/EP1005859B1/en not_active Expired - Lifetime
- 1999-11-29 DE DE69929411T patent/DE69929411T2/de not_active Expired - Lifetime
-
2001
- 2001-04-04 US US09/826,072 patent/US6387411B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
CA2290315A1 (en) | 2000-05-30 |
DE69929411D1 (de) | 2006-04-06 |
NO995687L (no) | 2000-05-31 |
ATE315381T1 (de) | 2006-02-15 |
DK1005859T3 (da) | 2006-04-03 |
US6242001B1 (en) | 2001-06-05 |
JP2000191684A (ja) | 2000-07-11 |
US6387411B2 (en) | 2002-05-14 |
ES2257011T3 (es) | 2006-07-16 |
EP1005859B1 (en) | 2006-01-11 |
CA2290315C (en) | 2008-11-18 |
EP1005859A1 (en) | 2000-06-07 |
US20010012521A1 (en) | 2001-08-09 |
DE69929411T2 (de) | 2006-08-24 |
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Legal Events
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FC2A | Withdrawal, rejection or dismissal of laid open patent application |