NO995531L - Nye mellomprodukter og fremgangsmåte for fremstilling derav - Google Patents

Nye mellomprodukter og fremgangsmåte for fremstilling derav

Info

Publication number
NO995531L
NO995531L NO995531A NO995531A NO995531L NO 995531 L NO995531 L NO 995531L NO 995531 A NO995531 A NO 995531A NO 995531 A NO995531 A NO 995531A NO 995531 L NO995531 L NO 995531L
Authority
NO
Norway
Prior art keywords
preparation
processes
new intermediates
thienyl
general formula
Prior art date
Application number
NO995531A
Other languages
English (en)
Other versions
NO325305B1 (no
NO995531D0 (no
Inventor
Alain Heymes
Bertrand Castro
Msria Bakonyi
Marianna Csatsrine Nagy
Leventene Molnsr
Original Assignee
Sanofi Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Synthelabo filed Critical Sanofi Synthelabo
Publication of NO995531D0 publication Critical patent/NO995531D0/no
Publication of NO995531L publication Critical patent/NO995531L/no
Publication of NO325305B1 publication Critical patent/NO325305B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
NO19995531A 1997-05-13 1999-11-12 Nye mellomprodukter, isomerer derav og fremgangsmate for fremstilling av disse NO325305B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU9700886A HU225504B1 (en) 1997-05-13 1997-05-13 Novel halophenyl-(2-(2-thienyl)-ethylamino)-acetonitriles and process for producing them
PCT/HU1998/000046 WO1998051682A1 (en) 1997-05-13 1998-05-11 New intermediates and process for the preparation thereof

Publications (3)

Publication Number Publication Date
NO995531D0 NO995531D0 (no) 1999-11-12
NO995531L true NO995531L (no) 1999-12-13
NO325305B1 NO325305B1 (no) 2008-03-25

Family

ID=89995121

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19995531A NO325305B1 (no) 1997-05-13 1999-11-12 Nye mellomprodukter, isomerer derav og fremgangsmate for fremstilling av disse

Country Status (14)

Country Link
US (1) US6215005B1 (no)
EP (1) EP0981525B1 (no)
JP (1) JP4279903B2 (no)
AT (1) ATE258551T1 (no)
AU (1) AU7444698A (no)
BR (1) BR9809113B1 (no)
CA (1) CA2288637C (no)
DE (1) DE69821347T2 (no)
DK (1) DK0981525T3 (no)
ES (1) ES2213900T3 (no)
HU (1) HU225504B1 (no)
NO (1) NO325305B1 (no)
PT (1) PT981525E (no)
WO (1) WO1998051682A1 (no)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU226421B1 (en) 1998-11-09 2008-12-29 Sanofi Aventis Process for racemizing optically active 2-(2-chlorophenyl)-2-(2-(2-thienyl)-ethylamino)-acetamides
US6495691B1 (en) 2001-07-06 2002-12-17 Brantford Chemicals Inc. Process for the preparation of tetrahydrothieno[3,2-c]pyridine derivatives
US6767913B2 (en) 2001-12-18 2004-07-27 Teva Pharmaceutical Industries Ltd. Crystal forms iii, iv, v, and novel amorphous form of clopidogrel hydrogensulfate, processes for their preparation, processes for the preparation of form i, compositions containing the new forms and methods of administering the new forms
US7074928B2 (en) 2002-01-11 2006-07-11 Teva Pharmaceutical Industries, Ltd. Polymorphs of clopidogrel hydrogensulfate
HUP0200438A3 (en) * 2002-02-06 2003-10-28 Egis Gyogyszergyar Nyilvanosan Novel clopidogrel hydrochloride polymorphs, process for the preparation thereof, their use and pharmaceutical compositions containing them
IL166593A0 (en) 2002-08-02 2006-01-15 Racemization and enantiomer separation of clopidogrel
US6800759B2 (en) 2002-08-02 2004-10-05 Teva Pharmaceutical Industries Ltd. Racemization and enantiomer separation of clopidogrel
EP1603920A1 (en) 2003-03-12 2005-12-14 Cadila Healthcare Ltd. Polymorph and amorphous form of (s)-(+)-clopidogrel bisulfate
US20040250673A1 (en) * 2003-06-10 2004-12-16 Salerno Paul Michael Ergonomic pedal board
GB0321256D0 (en) 2003-09-11 2003-10-08 Generics Uk Ltd Novel crystalline compounds
ATE455778T1 (de) 2003-11-03 2010-02-15 Cadila Healthcare Ltd Verfahren zur herstellung form i von (s)-(+)- clopidogrelbisulfat
US20060154957A1 (en) * 2004-09-21 2006-07-13 Nina Finkelstein Crystalline clopidogrel hydrobromide and processes for preparation thereof
US20060223845A1 (en) * 2005-02-24 2006-10-05 Eran Turgeman Clopidogrel base suitable for pharmaceutical formulation and preparation thereof
US8063217B2 (en) 2005-07-12 2011-11-22 Rpg Life Sciences Limited Process for preparation of methyl-(+)-(S)-alpha-(2-chlorophenyl)-6, 7-dihydrothieno[3,2-C]pyridine-5(4H) -acetic acid methyl ester or salts thereof having higher chiral purity and products thereof
RU2008146758A (ru) * 2006-04-27 2010-06-10 Инд-Свифт Лэборетриз Лимитед (In) Способ получения полиморфных форм клопидогрела гидросульфата
KR20080055860A (ko) * 2006-08-03 2008-06-19 테바 파마슈티컬 인더스트리즈 리미티드 클로피도그렐 바이설페이트의 제조 방법
EP1980563A1 (en) 2007-04-09 2008-10-15 BATTULA, Srinivasa Reddy Procedure for the preparation of methyl (+)-(S)-Alpha-(O-chlorophenyl)-6,7-dihydrothieno-[3,2-C]pyridine-5(4H) acetate
CN102186858A (zh) * 2008-10-24 2011-09-14 桑多斯股份公司 制备s-氯吡格雷的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2508455A1 (fr) 1981-06-30 1982-12-31 Sanofi Sa Procede de preparation de derives des (thienyl-2)- et (thienyl-3)-2 ethylamines
FR2530247B1 (fr) 1982-07-13 1986-05-16 Sanofi Sa Nouveaux derives de la thieno (3, 2-c) pyridine, leur procede de preparation et leur application therapeutique
FR2608607B1 (fr) 1986-12-23 1989-04-28 Sanofi Sa Procede de preparation de thienylethylamines et dithienylethylamines ainsi obtenues
FR2623810B2 (fr) * 1987-02-17 1992-01-24 Sanofi Sa Sels de l'alpha-(tetrahydro-4,5,6,7 thieno(3,2-c) pyridyl-5) (chloro-2 phenyl) -acetate de methyle dextrogyre et compositions pharmaceutiques en contenant
FR2614619B1 (fr) 1987-04-29 1989-09-15 Sanofi Sa Procede de preparation de n-((chloro-2)-benzyl) (thienyl-2)-2 ethylamine
FR2652575B1 (fr) * 1989-09-29 1992-01-24 Sanofi Sa Procede de preparation d'acides alpha-bromo phenylacetiques.
FR2664596B1 (fr) * 1990-07-10 1994-06-10 Sanofi Sa Procede de preparation d'un derive n-phenylacetique de tetrahydrothieno [3,2-c] pyridine et son intermediaire de synthese.
AU732332B2 (en) * 1996-09-12 2001-04-12 Aventis Pharmaceuticals Inc. Stereospecific preparation of chiral 1-aryl- and 1-heteroaryl-2-substituted ethyl-2-amines

Also Published As

Publication number Publication date
AU7444698A (en) 1998-12-08
BR9809113A (pt) 2000-08-01
HUP9700886A3 (en) 2000-06-28
ES2213900T3 (es) 2004-09-01
WO1998051682A1 (en) 1998-11-19
BR9809113B1 (pt) 2010-03-09
CA2288637A1 (en) 1998-11-19
DE69821347T2 (de) 2004-12-02
HUP9700886A2 (hu) 1999-09-28
HU225504B1 (en) 2007-01-29
PT981525E (pt) 2004-05-31
DE69821347D1 (de) 2004-03-04
EP0981525B1 (en) 2004-01-28
EP0981525A1 (en) 2000-03-01
CA2288637C (en) 2005-11-15
HU9700886D0 (en) 1997-07-28
DK0981525T3 (da) 2004-05-10
NO325305B1 (no) 2008-03-25
ATE258551T1 (de) 2004-02-15
US6215005B1 (en) 2001-04-10
NO995531D0 (no) 1999-11-12
JP4279903B2 (ja) 2009-06-17
JP2001525817A (ja) 2001-12-11

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