NO995033L - 6,7-disubstituerte-4-aminopyrido[2,3-D]pyrimidinforbindelser - Google Patents
6,7-disubstituerte-4-aminopyrido[2,3-D]pyrimidinforbindelserInfo
- Publication number
- NO995033L NO995033L NO995033A NO995033A NO995033L NO 995033 L NO995033 L NO 995033L NO 995033 A NO995033 A NO 995033A NO 995033 A NO995033 A NO 995033A NO 995033 L NO995033 L NO 995033L
- Authority
- NO
- Norway
- Prior art keywords
- compound
- administering
- effective amount
- therapeutically effective
- aminopyrido
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Diabetes (AREA)
- Rheumatology (AREA)
- Vascular Medicine (AREA)
- Physical Education & Sports Medicine (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Transplantation (AREA)
- Urology & Nephrology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychiatry (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Forbindelse som har formel (I): R1^X ro hvor R1, R2, R3 og R4 er definerte variabler valgt fra gruppene som spesifisert her, hvilke inkluderer alkyl, aryl, heteroaryl og heterosyklyl, og substituerte versjoner derav, en fremgangsmåte ved inhibering av adenosinkinase ved å administrere en forbindelse derav, en farmasøytisk sammensetning omfattende en terapeutisk effektiv mengde av en forbindelse derav ovenfor, i kombinasjon med en farma- søytisk akseptabel bærer, en fremgangsmåte ved behandling av cerebral iskemi, epilepsi nocipersepsjon, smerte, inflammasjon og sepsis i et pattedyr som trenger slik behandling, omfattende å administrere til pattedyret en terapeutisk effektiv mengde av en forbindelse derav, og fremgangsmåter ved fremstilling derav.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US83439397A | 1997-04-16 | 1997-04-16 | |
| PCT/US1998/004127 WO1998046603A1 (en) | 1997-04-16 | 1998-04-16 | 6,7-disubstituted-4-aminopyrido[2,3-d]pyrimidine compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO995033D0 NO995033D0 (no) | 1999-10-15 |
| NO995033L true NO995033L (no) | 1999-12-15 |
Family
ID=25266829
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO995033A NO995033L (no) | 1997-04-16 | 1999-10-15 | 6,7-disubstituerte-4-aminopyrido[2,3-D]pyrimidinforbindelser |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP0979230A1 (no) |
| JP (1) | JP2001520649A (no) |
| KR (1) | KR20010006453A (no) |
| CN (1) | CN1259948A (no) |
| AR (1) | AR012435A1 (no) |
| AU (1) | AU744528B2 (no) |
| BG (1) | BG103861A (no) |
| BR (1) | BR9809088A (no) |
| CA (1) | CA2287465A1 (no) |
| CO (1) | CO4940439A1 (no) |
| HU (1) | HUP0001402A3 (no) |
| IL (1) | IL131892A0 (no) |
| NO (1) | NO995033L (no) |
| NZ (1) | NZ337844A (no) |
| PL (1) | PL336262A1 (no) |
| SK (1) | SK142099A3 (no) |
| TR (1) | TR199902456T2 (no) |
| TW (1) | TW458977B (no) |
| WO (1) | WO1998046603A1 (no) |
| ZA (1) | ZA982912B (no) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001057040A1 (en) * | 2000-02-03 | 2001-08-09 | Abbott Laboratories | 6,7-disubstituted-4-aminopyrido[2,3-d]pyrimidine compounds |
| PL366918A1 (en) * | 2001-02-12 | 2005-02-07 | F.Hoffmann-La Roche Ag | 6-substituted pyrido-pyrimidines |
| KR20070086076A (ko) | 2004-11-12 | 2007-08-27 | 트러스티즈 오브 터프츠 칼리지 | 리파아제 억제제 |
| EP2139332A4 (en) * | 2007-03-28 | 2010-04-21 | Merck Sharp & Dohme | SUBSTITUTED PYRIDO [2,3-D] PYRIMIDINE DERIVATIVES AS CANNABINOID-1 RECEPTOR MODULATORS |
| BR112015007182A2 (pt) * | 2012-10-05 | 2017-07-04 | Rigel Pharmaceuticals Inc | inibidores de gdf-8 |
| WO2017205848A1 (en) * | 2016-05-27 | 2017-11-30 | Legacy Emanuel Hospital & Health Center | Methanocarba derivatives of pseudoribose that inhibit adenosine kinase |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB774094A (en) * | 1953-01-02 | 1957-05-08 | Wellcome Found | Improvements in or relating to pyrimidine compounds |
| IL112249A (en) * | 1994-01-25 | 2001-11-25 | Warner Lambert Co | Pharmaceutical compositions containing di and tricyclic pyrimidine derivatives for inhibiting tyrosine kinases of the epidermal growth factor receptor family and some new such compounds |
-
1998
- 1998-03-27 TW TW087104674A patent/TW458977B/zh not_active IP Right Cessation
- 1998-04-06 ZA ZA982912A patent/ZA982912B/xx unknown
- 1998-04-14 CO CO98020309A patent/CO4940439A1/es unknown
- 1998-04-15 AR ARP980101732A patent/AR012435A1/es unknown
- 1998-04-16 BR BR9809088-7A patent/BR9809088A/pt not_active IP Right Cessation
- 1998-04-16 NZ NZ337844A patent/NZ337844A/en unknown
- 1998-04-16 TR TR1999/02456T patent/TR199902456T2/xx unknown
- 1998-04-16 AU AU70981/98A patent/AU744528B2/en not_active Ceased
- 1998-04-16 KR KR1019997009543A patent/KR20010006453A/ko not_active Application Discontinuation
- 1998-04-16 WO PCT/US1998/004127 patent/WO1998046603A1/en not_active Application Discontinuation
- 1998-04-16 IL IL13189298A patent/IL131892A0/xx unknown
- 1998-04-16 JP JP54387898A patent/JP2001520649A/ja active Pending
- 1998-04-16 PL PL98336262A patent/PL336262A1/xx unknown
- 1998-04-16 CA CA002287465A patent/CA2287465A1/en not_active Abandoned
- 1998-04-16 HU HU0001402A patent/HUP0001402A3/hu unknown
- 1998-04-16 EP EP98917950A patent/EP0979230A1/en not_active Withdrawn
- 1998-04-16 CN CN98806072A patent/CN1259948A/zh active Pending
- 1998-04-16 SK SK1420-99A patent/SK142099A3/sk unknown
-
1999
- 1999-10-15 NO NO995033A patent/NO995033L/no not_active Application Discontinuation
- 1999-11-05 BG BG103861A patent/BG103861A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| TW458977B (en) | 2001-10-11 |
| KR20010006453A (ko) | 2001-01-26 |
| AU744528B2 (en) | 2002-02-28 |
| PL336262A1 (en) | 2000-06-19 |
| ZA982912B (en) | 1998-10-09 |
| BG103861A (en) | 2000-06-30 |
| AR012435A1 (es) | 2000-10-18 |
| EP0979230A1 (en) | 2000-02-16 |
| TR199902456T2 (xx) | 2000-07-21 |
| BR9809088A (pt) | 2000-08-01 |
| CN1259948A (zh) | 2000-07-12 |
| NO995033D0 (no) | 1999-10-15 |
| SK142099A3 (en) | 2000-05-16 |
| NZ337844A (en) | 2001-11-30 |
| CO4940439A1 (es) | 2000-07-24 |
| JP2001520649A (ja) | 2001-10-30 |
| HUP0001402A2 (hu) | 2000-10-28 |
| IL131892A0 (en) | 2001-03-19 |
| CA2287465A1 (en) | 1998-10-22 |
| HUP0001402A3 (en) | 2001-01-29 |
| AU7098198A (en) | 1998-11-11 |
| WO1998046603A1 (en) | 1998-10-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |