AR012435A1 - Compuesto de 4-aminopirido[2,3-d]pirimidina 6,7-disustituida; el uso del mismo para la manufactura de un medicamento, procedimiento para su preparacion,composicion farmaceutica que lo contiene, compuestos intermediarios y procedimiento para su preparacion. - Google Patents
Compuesto de 4-aminopirido[2,3-d]pirimidina 6,7-disustituida; el uso del mismo para la manufactura de un medicamento, procedimiento para su preparacion,composicion farmaceutica que lo contiene, compuestos intermediarios y procedimiento para su preparacion.Info
- Publication number
- AR012435A1 AR012435A1 ARP980101732A ARP980101732A AR012435A1 AR 012435 A1 AR012435 A1 AR 012435A1 AR P980101732 A ARP980101732 A AR P980101732A AR P980101732 A ARP980101732 A AR P980101732A AR 012435 A1 AR012435 A1 AR 012435A1
- Authority
- AR
- Argentina
- Prior art keywords
- compound
- preparation
- procedure
- aryl
- manufacture
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Diabetes (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Communicable Diseases (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Psychiatry (AREA)
- Transplantation (AREA)
- Oncology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Un compuesto de 4-aminopirido[2,3-D]piridina 6,7-disustituida y las sales y amidas farmacéuticamente aceptable del mismo que tiene las sigiuente formula Ien la cual: R1 y R2, independientemente entre si, son, hidrogeno, alquilo inferior, aril alquilo o acilo, o pueden ser tomados conjuntamente con el átomode nitrogeno al cual están fijados de manera de formar un anillo de 5 a 7 miembros que opcionalmente contienen un átomo adicional de oxígeno o un átomode nitrogeno; R3 y R4, independientemente entre sí, son seleccionados de entre; alquilo inferior, alquenilo inferior, arilo, aril, alquilo, hetero arilo, o ungrupo hetero cíclico, y las líneas de trazos indican que opcionalmente hay un doble enlace presente inhibir la adenosínquinasa, una composicion farmacéuticaque comprende una cantidad efectiva desde el punto de vista terapéutico de un compuesto de la presente en combinacion con un vehículo farmacéuticamenteaceptable, el uso de dicho compuesto para la manufactura deun medicamento util para tratar la isquemia cerebral, la epilepsia, la noci percepcion, el dolor,la inflamacion y la sepsis en un mamífero que lo necesite, que comprende una cantidad efectiva desde el punto de vista terapéutico, de un compuesto dela presente; procedimientos para la preparacion del compuesto; compuestos intermediarios y procedimientos para su preparacion; el uso del mismo para lamanufactura de un medicamento util.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US83439397A | 1997-04-16 | 1997-04-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR012435A1 true AR012435A1 (es) | 2000-10-18 |
Family
ID=25266829
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP980101732A AR012435A1 (es) | 1997-04-16 | 1998-04-15 | Compuesto de 4-aminopirido[2,3-d]pirimidina 6,7-disustituida; el uso del mismo para la manufactura de un medicamento, procedimiento para su preparacion,composicion farmaceutica que lo contiene, compuestos intermediarios y procedimiento para su preparacion. |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP0979230A1 (es) |
| JP (1) | JP2001520649A (es) |
| KR (1) | KR20010006453A (es) |
| CN (1) | CN1259948A (es) |
| AR (1) | AR012435A1 (es) |
| AU (1) | AU744528B2 (es) |
| BG (1) | BG103861A (es) |
| BR (1) | BR9809088A (es) |
| CA (1) | CA2287465A1 (es) |
| CO (1) | CO4940439A1 (es) |
| HU (1) | HUP0001402A3 (es) |
| IL (1) | IL131892A0 (es) |
| NO (1) | NO995033L (es) |
| NZ (1) | NZ337844A (es) |
| PL (1) | PL336262A1 (es) |
| SK (1) | SK142099A3 (es) |
| TR (1) | TR199902456T2 (es) |
| TW (1) | TW458977B (es) |
| WO (1) | WO1998046603A1 (es) |
| ZA (1) | ZA982912B (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001057040A1 (en) * | 2000-02-03 | 2001-08-09 | Abbott Laboratories | 6,7-disubstituted-4-aminopyrido[2,3-d]pyrimidine compounds |
| BRPI0207172B8 (pt) * | 2001-02-12 | 2021-05-25 | Hoffmann La Roche | pirido-pirimidinas 6-substituída, sua composição e seu uso, bem como seu intermediário |
| EP1824861A2 (en) | 2004-11-12 | 2007-08-29 | Trustees of the Tufts College | Lipase inhibitors |
| WO2008121257A1 (en) * | 2007-03-28 | 2008-10-09 | Merck & Co., Inc. | Substituted pyrido[2,3-d]pyrimidine derivatives as cannabinoid-1 receptor modulators |
| EA201590693A1 (ru) * | 2012-10-05 | 2015-08-31 | Ригель Фармасьютикалс, Инк. | Ингибиторы gdf-8 |
| WO2017205848A1 (en) * | 2016-05-27 | 2017-11-30 | Legacy Emanuel Hospital & Health Center | Methanocarba derivatives of pseudoribose that inhibit adenosine kinase |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB774094A (en) * | 1953-01-02 | 1957-05-08 | Wellcome Found | Improvements in or relating to pyrimidine compounds |
| IL112249A (en) * | 1994-01-25 | 2001-11-25 | Warner Lambert Co | Pharmaceutical compositions containing di and tricyclic pyrimidine derivatives for inhibiting tyrosine kinases of the epidermal growth factor receptor family and some new such compounds |
-
1998
- 1998-03-27 TW TW087104674A patent/TW458977B/zh not_active IP Right Cessation
- 1998-04-06 ZA ZA982912A patent/ZA982912B/xx unknown
- 1998-04-14 CO CO98020309A patent/CO4940439A1/es unknown
- 1998-04-15 AR ARP980101732A patent/AR012435A1/es unknown
- 1998-04-16 HU HU0001402A patent/HUP0001402A3/hu unknown
- 1998-04-16 BR BR9809088-7A patent/BR9809088A/pt not_active IP Right Cessation
- 1998-04-16 IL IL13189298A patent/IL131892A0/xx unknown
- 1998-04-16 CN CN98806072A patent/CN1259948A/zh active Pending
- 1998-04-16 AU AU70981/98A patent/AU744528B2/en not_active Ceased
- 1998-04-16 TR TR1999/02456T patent/TR199902456T2/xx unknown
- 1998-04-16 WO PCT/US1998/004127 patent/WO1998046603A1/en not_active Application Discontinuation
- 1998-04-16 JP JP54387898A patent/JP2001520649A/ja active Pending
- 1998-04-16 CA CA002287465A patent/CA2287465A1/en not_active Abandoned
- 1998-04-16 NZ NZ337844A patent/NZ337844A/en unknown
- 1998-04-16 SK SK1420-99A patent/SK142099A3/sk unknown
- 1998-04-16 EP EP98917950A patent/EP0979230A1/en not_active Withdrawn
- 1998-04-16 KR KR1019997009543A patent/KR20010006453A/ko not_active Application Discontinuation
- 1998-04-16 PL PL98336262A patent/PL336262A1/xx unknown
-
1999
- 1999-10-15 NO NO995033A patent/NO995033L/no not_active Application Discontinuation
- 1999-11-05 BG BG103861A patent/BG103861A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| TR199902456T2 (xx) | 2000-07-21 |
| NO995033L (no) | 1999-12-15 |
| KR20010006453A (ko) | 2001-01-26 |
| WO1998046603A1 (en) | 1998-10-22 |
| BG103861A (en) | 2000-06-30 |
| ZA982912B (en) | 1998-10-09 |
| PL336262A1 (en) | 2000-06-19 |
| TW458977B (en) | 2001-10-11 |
| CN1259948A (zh) | 2000-07-12 |
| CO4940439A1 (es) | 2000-07-24 |
| EP0979230A1 (en) | 2000-02-16 |
| NZ337844A (en) | 2001-11-30 |
| HUP0001402A3 (en) | 2001-01-29 |
| AU7098198A (en) | 1998-11-11 |
| AU744528B2 (en) | 2002-02-28 |
| HUP0001402A2 (hu) | 2000-10-28 |
| CA2287465A1 (en) | 1998-10-22 |
| NO995033D0 (no) | 1999-10-15 |
| SK142099A3 (en) | 2000-05-16 |
| JP2001520649A (ja) | 2001-10-30 |
| BR9809088A (pt) | 2000-08-01 |
| IL131892A0 (en) | 2001-03-19 |
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| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |