NO991571L - FremgangsmÕte for mikroinnkapsling av et kjernemateriale ved anvendelse av superkritiske vµsker - Google Patents

FremgangsmÕte for mikroinnkapsling av et kjernemateriale ved anvendelse av superkritiske vµsker

Info

Publication number
NO991571L
NO991571L NO991571A NO991571A NO991571L NO 991571 L NO991571 L NO 991571L NO 991571 A NO991571 A NO 991571A NO 991571 A NO991571 A NO 991571A NO 991571 L NO991571 L NO 991571L
Authority
NO
Norway
Prior art keywords
core material
polymer
microencapsulating
fluid
supercritical
Prior art date
Application number
NO991571A
Other languages
English (en)
Other versions
NO991571D0 (no
Inventor
Annette Dudek Shine
Jr Jack Gelb
Original Assignee
Univ Delaware
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Delaware filed Critical Univ Delaware
Publication of NO991571D0 publication Critical patent/NO991571D0/no
Publication of NO991571L publication Critical patent/NO991571L/no

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2984—Microcapsule with fluid core [includes liposome]
    • Y10T428/2985—Solid-walled microcapsule from synthetic polymer
    • Y10T428/2987—Addition polymer from unsaturated monomers only
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2989—Microcapsule with solid core [includes liposome]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicinal Preparation (AREA)

Abstract

Fremgangsmåte for mikroinnkapsling av et kjernemateriale, omfattende trinnene a) blande et kjernemateriale med en mikro-innkapslende polymer, b) tilføre til blandingen et superkritisk fluid med evne til å svelle polymeren under til-strekkelig trykk og temperatur til å holde fluidet i en superkritisk tilstand, c) la det superkritiske fluid trenge inn i og flytendegjøre polymeren, samtidig som temperatur og trykk er til-strekkelig til å holde fluidet i en superkritisk tilstand, og d) hurtig avlaste trykket slik at polymeren stivner rundt kjernematerialet og danner en mikrokapsel. Med denne fremgangsmåte er det ikke nødvendig at hverken polymer eller kjernematerialer er løselige i det superkritiske fluid. Fremgangsmåten kan anvendes for hurtig og effektiv mikroinnkapsling av en rekke materialer for forskjellige anvendelser.
NO991571A 1996-10-08 1999-03-30 FremgangsmÕte for mikroinnkapsling av et kjernemateriale ved anvendelse av superkritiske vµsker NO991571L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/727,154 US5766637A (en) 1996-10-08 1996-10-08 Microencapsulation process using supercritical fluids
PCT/US1997/017509 WO1998015348A1 (en) 1996-10-08 1997-10-01 Microencapsulation process using supercritical fluids

Publications (2)

Publication Number Publication Date
NO991571D0 NO991571D0 (no) 1999-03-30
NO991571L true NO991571L (no) 1999-06-07

Family

ID=24921541

Family Applications (1)

Application Number Title Priority Date Filing Date
NO991571A NO991571L (no) 1996-10-08 1999-03-30 FremgangsmÕte for mikroinnkapsling av et kjernemateriale ved anvendelse av superkritiske vµsker

Country Status (14)

Country Link
US (1) US5766637A (no)
EP (1) EP0948396A1 (no)
JP (1) JP2000511110A (no)
CN (1) CN1232411A (no)
AR (1) AR008867A1 (no)
AU (1) AU713965B2 (no)
BR (1) BR9711590A (no)
CA (1) CA2267350A1 (no)
CO (1) CO4900026A1 (no)
IN (1) IN183694B (no)
NO (1) NO991571L (no)
NZ (1) NZ334815A (no)
PE (1) PE1499A1 (no)
WO (1) WO1998015348A1 (no)

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Also Published As

Publication number Publication date
IN183694B (no) 2000-03-18
CN1232411A (zh) 1999-10-20
CO4900026A1 (es) 2000-03-27
BR9711590A (pt) 1999-08-24
PE1499A1 (es) 1999-02-11
EP0948396A1 (en) 1999-10-13
AU713965B2 (en) 1999-12-16
NZ334815A (en) 2001-01-26
NO991571D0 (no) 1999-03-30
US5766637A (en) 1998-06-16
WO1998015348A1 (en) 1998-04-16
AU4602797A (en) 1998-05-05
CA2267350A1 (en) 1998-04-16
AR008867A1 (es) 2000-02-23
JP2000511110A (ja) 2000-08-29

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