DK0488142T3 - Fremgangsmåde til indkapsling af faste eller flydende, lipofile virksomme stoffer i phospholipid-liposomer samt lægemidler indeholdende disse liposomer - Google Patents
Fremgangsmåde til indkapsling af faste eller flydende, lipofile virksomme stoffer i phospholipid-liposomer samt lægemidler indeholdende disse liposomerInfo
- Publication number
- DK0488142T3 DK0488142T3 DK91120118.4T DK91120118T DK0488142T3 DK 0488142 T3 DK0488142 T3 DK 0488142T3 DK 91120118 T DK91120118 T DK 91120118T DK 0488142 T3 DK0488142 T3 DK 0488142T3
- Authority
- DK
- Denmark
- Prior art keywords
- liposomes
- phospholipid
- temp
- hydration medium
- active substances
- Prior art date
Links
- 150000003904 phospholipids Chemical class 0.000 title abstract 5
- 239000002502 liposome Substances 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 3
- 239000013543 active substance Substances 0.000 title abstract 2
- 239000007787 solid Substances 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 239000007788 liquid Substances 0.000 title 1
- 230000036571 hydration Effects 0.000 abstract 4
- 238000006703 hydration reaction Methods 0.000 abstract 4
- HZAXFHJVJLSVMW-UHFFFAOYSA-N 2-Aminoethan-1-ol Chemical compound NCCO HZAXFHJVJLSVMW-UHFFFAOYSA-N 0.000 abstract 2
- 238000003756 stirring Methods 0.000 abstract 2
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 230000003115 biocidal effect Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000003599 detergent Substances 0.000 abstract 1
- 239000006185 dispersion Substances 0.000 abstract 1
- 239000005556 hormone Substances 0.000 abstract 1
- 229940088597 hormone Drugs 0.000 abstract 1
- 230000000887 hydrating effect Effects 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1277—Preparation processes; Proliposomes
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Dispersion Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4038075A DE4038075C1 (en) | 1990-11-29 | 1990-11-29 | Encapsulating solid or liq. lipophilic agents - comprises mixing hydration medium with phospholipid increasing temp. to above soln. phase change temp. and adding remaining medium |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0488142T3 true DK0488142T3 (da) | 1995-06-26 |
Family
ID=6419221
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK91120118.4T DK0488142T3 (da) | 1990-11-29 | 1991-11-26 | Fremgangsmåde til indkapsling af faste eller flydende, lipofile virksomme stoffer i phospholipid-liposomer samt lægemidler indeholdende disse liposomer |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0488142B1 (da) |
| AT (1) | ATE117544T1 (da) |
| DE (2) | DE4038075C1 (da) |
| DK (1) | DK0488142T3 (da) |
| ES (1) | ES2068473T3 (da) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4132677C2 (de) * | 1991-10-01 | 1995-08-24 | Braun Melsungen Ag | Flüchtige Inhalationsnarkotika enthaltende Liposomen, ihre Herstellung und Verwendung |
| FR2689418B1 (fr) * | 1992-04-03 | 1994-07-01 | Centre Nat Rech Scient | Procede de preparation de micro-capsules ou de liposomes de tailles controlees par application d'un cisaillement constant sur une phase lamellaire. |
| FR2716110B1 (fr) * | 1994-02-16 | 1996-04-05 | Roussel Uclaf | Compositions cosmétiques ou pharmaceutiques comprenant des liposomes. |
| GB9605915D0 (en) * | 1996-03-21 | 1996-05-22 | Univ Bruxelles | Liposome encapsulated amphiphilic drug compositions |
| AU2066897A (en) * | 1996-03-27 | 1997-10-17 | Ortho Pharmaceutical Corporation | Manufacture of liposomes and lipid-protein complexes by ethanolic injection and thin film evaporation |
| IT1289939B1 (it) * | 1997-02-20 | 1998-10-19 | Angelini Ricerche Spa | Composizione farmaceutica acquosa comprendente un principio attivo altamente insolubile in acqua |
| RU2134967C1 (ru) * | 1997-05-30 | 1999-08-27 | Шестаков Константин Алексеевич | Способ получения микрокапсулированных препаратов, содержащих пиретроидные инсектициды |
| US8658202B2 (en) | 2001-04-25 | 2014-02-25 | Western University Of Health Sciences | Coated drug delivery formulations |
| US6759058B1 (en) * | 2001-04-25 | 2004-07-06 | Western Center For Drug Development College Of Pharmacy Western University Of Health Sciences | Enteric-coated proliposomal formulations for poorly water soluble drugs |
| ES2275443B1 (es) * | 2005-11-30 | 2008-06-01 | Italfarmaco, S.A. | Procedimiento de preparacion de liposomas. |
| CN119969509A (zh) * | 2025-03-07 | 2025-05-13 | 安庆师范大学 | 一种宠物益生菌双层脂质体及其制备方法和应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL7809709A (nl) * | 1977-09-30 | 1979-04-03 | Farmaceutici Italia | Werkwijze voor het bereiden van injecteerbare liposomen |
| JPS5841814A (ja) * | 1981-08-10 | 1983-03-11 | ザ・ウエルカム・フアウンデ−シヨン・リミテツド | 抗レ−シユマニア症薬剤組成物およびその製造法 |
| FR2562421B1 (fr) * | 1984-04-09 | 1989-02-17 | Sandoz Sa | Perfectionnements a la therapie par l'interleukine |
| IL79114A (en) * | 1985-08-07 | 1990-09-17 | Allergan Pharma | Method and composition for making liposomes |
| CA1338702C (en) * | 1987-03-05 | 1996-11-12 | Lawrence D. Mayer | High drug:lipid formulations of liposomal- antineoplastic agents |
| IL94103A0 (en) * | 1989-04-25 | 1991-01-31 | Nattermann A & Cie | Water-containing formulations with phospholipids,their preparation and application |
-
1990
- 1990-11-29 DE DE4038075A patent/DE4038075C1/de not_active Expired - Lifetime
-
1991
- 1991-11-26 AT AT91120118T patent/ATE117544T1/de not_active IP Right Cessation
- 1991-11-26 EP EP91120118A patent/EP0488142B1/de not_active Expired - Lifetime
- 1991-11-26 DE DE59104404T patent/DE59104404D1/de not_active Expired - Fee Related
- 1991-11-26 DK DK91120118.4T patent/DK0488142T3/da active
- 1991-11-26 ES ES91120118T patent/ES2068473T3/es not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ATE117544T1 (de) | 1995-02-15 |
| DE4038075C1 (en) | 1992-03-19 |
| EP0488142B1 (de) | 1995-01-25 |
| EP0488142A1 (de) | 1992-06-03 |
| DE59104404D1 (de) | 1995-03-09 |
| ES2068473T3 (es) | 1995-04-16 |
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