NO990849D0 - Substituerte 1,2,3,4-tetrahydro-2-dibenzofuranaminer og 2-aminocyklohepta (b) benzofuraner - Google Patents
Substituerte 1,2,3,4-tetrahydro-2-dibenzofuranaminer og 2-aminocyklohepta (b) benzofuranerInfo
- Publication number
- NO990849D0 NO990849D0 NO990849A NO990849A NO990849D0 NO 990849 D0 NO990849 D0 NO 990849D0 NO 990849 A NO990849 A NO 990849A NO 990849 A NO990849 A NO 990849A NO 990849 D0 NO990849 D0 NO 990849D0
- Authority
- NO
- Norway
- Prior art keywords
- aminocyclohepta
- substituted
- dibenzofuranamines
- benzofurans
- tetrahydro
- Prior art date
Links
- GJUCAWYIAWECBW-UHFFFAOYSA-N 1h-cyclohepta[b][1]benzofuran-2-amine Chemical class O1C2=CC=CC=CC2=C2C1=CC=C(N)C2 GJUCAWYIAWECBW-UHFFFAOYSA-N 0.000 title abstract 2
- JCFPKIOSTZEMSZ-UHFFFAOYSA-N 1,2,3,4-tetrahydrodibenzofuran-2-amine Chemical class O1C2=CC=CC=C2C2=C1CCC(N)C2 JCFPKIOSTZEMSZ-UHFFFAOYSA-N 0.000 title 1
- 102100036311 5-hydroxytryptamine receptor 1F Human genes 0.000 abstract 1
- 101710138086 5-hydroxytryptamine receptor 1F Proteins 0.000 abstract 1
- 239000000556 agonist Substances 0.000 abstract 1
- -1 substituted-2-amino-1,2,3,4-tetrahydrodibenzofurans Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/91—Dibenzofurans; Hydrogenated dibenzofurans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Polyethers (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2474596P | 1996-08-28 | 1996-08-28 | |
| PCT/US1997/014938 WO1998008502A1 (en) | 1996-08-28 | 1997-08-25 | SUBSTITUTED 1,2,3,4-TETRAHYDRO-2-DIBENZOFURANAMINES AND 2-AMINOCYCLOHEPTA[b]BENZOFURANS |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO990849L NO990849L (no) | 1999-02-23 |
| NO990849D0 true NO990849D0 (no) | 1999-02-23 |
Family
ID=21822177
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO990849A NO990849D0 (no) | 1996-08-28 | 1999-02-23 | Substituerte 1,2,3,4-tetrahydro-2-dibenzofuranaminer og 2-aminocyklohepta (b) benzofuraner |
Country Status (23)
| Country | Link |
|---|---|
| EP (1) | EP0929299B1 (da) |
| JP (1) | JP2000516957A (da) |
| KR (1) | KR20000035942A (da) |
| CN (1) | CN1228695A (da) |
| AT (1) | ATE251457T1 (da) |
| AU (1) | AU741324B2 (da) |
| BR (1) | BR9711273A (da) |
| CA (1) | CA2264267A1 (da) |
| CZ (1) | CZ64499A3 (da) |
| DE (1) | DE69725459T2 (da) |
| DK (1) | DK0929299T3 (da) |
| EA (1) | EA001912B1 (da) |
| ES (1) | ES2208948T3 (da) |
| HU (1) | HUP9902901A3 (da) |
| IL (1) | IL128500A (da) |
| NO (1) | NO990849D0 (da) |
| NZ (1) | NZ334031A (da) |
| PL (1) | PL331882A1 (da) |
| PT (1) | PT929299E (da) |
| TR (1) | TR199900430T2 (da) |
| UA (1) | UA48245C2 (da) |
| WO (1) | WO1998008502A1 (da) |
| YU (1) | YU10499A (da) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA52778C2 (uk) | 1997-10-10 | 2003-01-15 | Янссен Фармацевтика Н.В. | Галогенозаміщені тетрациклічні похідні тетрагідрофурану, спосіб їх отримання та композиція на їх основі |
| TWI263497B (en) | 2002-03-29 | 2006-10-11 | Lilly Co Eli | Pyridinoylpiperidines as 5-HT1F agonists |
| BRPI0409211A (pt) | 2003-04-18 | 2006-03-28 | Lilly Co Eli | composto, composição farmacêutica, métodos para ativar receptores 5-ht1f, para inibir extravasão de proteìna neuronial, e para o tratamento ou prevenção de enxaqueca em um mamìfero, e, uso de um composto |
| UA82711C2 (en) | 2003-09-12 | 2008-05-12 | Эли Лилли Энд Компани | Substituted 2-carbonylamino-6-piperidinaminopyridines and substituted 1-carbonylamino-3-piperidinaminobenzenes as 5-ht1f agonists |
| DE602004008338T2 (de) | 2003-12-17 | 2008-05-29 | Eli Lilly And Co., Indianapolis | Substituierte (4-aminocyclohexen-1-yl) phenyl and (4-aminocyclohexen-1-yl) pyridinyl verbindungen als 5-ht1f agonisten |
| CN1318411C (zh) * | 2005-03-21 | 2007-05-30 | 中国海洋大学 | 氢化轮枝霉酮类化合物及其制备方法和用途 |
| PL2413933T5 (pl) | 2009-04-02 | 2021-10-18 | Colucid Pharmaceuticals, Inc. | 2,4,6-trifluoro-N-[6-(1-metylopiperydyno-4-karbonylo)pirydyn-2-ylo]benzamid do leczenia migreny drogą doustną lub dożylną |
| US8697876B2 (en) | 2010-04-02 | 2014-04-15 | Colucid Pharmaceuticals, Inc. | Compositions and methods of synthesis of pyridinolypiperidine 5-HT1F agonists |
| CN102887880B (zh) * | 2012-08-20 | 2014-10-29 | 东南大学 | 二苯并呋喃衍生物及其制备方法与用途 |
| TWI826514B (zh) | 2018-09-04 | 2023-12-21 | 美商美國禮來大藥廠 | 用於預防偏頭痛之拉米迪坦(lasmiditan)長期夜間投藥 |
| TWI776175B (zh) | 2019-07-09 | 2022-09-01 | 美商美國禮來大藥廠 | 大規模製備2,4,6-三氟-n-[6-(1-甲基-哌啶-4-羰基)-吡啶-2-基]-苯甲醯胺半琥珀酸鹽的方法及中間體，以及2,4,6-三氟-n-[6-(1-甲基-哌啶-4-羰基)-吡啶-2-基]-苯甲醯胺醋酸鹽之製備 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4668690A (en) * | 1985-12-30 | 1987-05-26 | Hoechst Roussel Pharmaceuticals Inc. | 1,2,3,4,4a,9b-hexahydro-4a-aminoalkyldibenzofurans useful as analgesics, anticonvulsants or antidepressants |
| US5698571A (en) * | 1994-10-05 | 1997-12-16 | Eli Lilly And Company | 5-HT1F mediated inhibition of neurogenic meningeal extravasation: a method for the treatment of migraine |
| US5521196A (en) * | 1994-10-05 | 1996-05-28 | Eli Lilly And Company | 5-HT1F agonists for the treatment of migraine |
-
1997
- 1997-08-25 JP JP10511794A patent/JP2000516957A/ja not_active Ceased
- 1997-08-25 NZ NZ334031A patent/NZ334031A/xx unknown
- 1997-08-25 TR TR1999/00430T patent/TR199900430T2/xx unknown
- 1997-08-25 DK DK97938585T patent/DK0929299T3/da active
- 1997-08-25 IL IL12850097A patent/IL128500A/xx not_active IP Right Cessation
- 1997-08-25 CA CA002264267A patent/CA2264267A1/en not_active Abandoned
- 1997-08-25 CN CN97197483A patent/CN1228695A/zh active Pending
- 1997-08-25 HU HU9902901A patent/HUP9902901A3/hu unknown
- 1997-08-25 EA EA199900241A patent/EA001912B1/ru not_active IP Right Cessation
- 1997-08-25 PT PT97938585T patent/PT929299E/pt unknown
- 1997-08-25 KR KR1019997001683A patent/KR20000035942A/ko not_active Ceased
- 1997-08-25 UA UA99021147A patent/UA48245C2/uk unknown
- 1997-08-25 ES ES97938585T patent/ES2208948T3/es not_active Expired - Lifetime
- 1997-08-25 WO PCT/US1997/014938 patent/WO1998008502A1/en not_active Ceased
- 1997-08-25 BR BR9711273A patent/BR9711273A/pt not_active IP Right Cessation
- 1997-08-25 AU AU40880/97A patent/AU741324B2/en not_active Ceased
- 1997-08-25 PL PL97331882A patent/PL331882A1/xx unknown
- 1997-08-25 DE DE69725459T patent/DE69725459T2/de not_active Expired - Fee Related
- 1997-08-25 EP EP97938585A patent/EP0929299B1/en not_active Expired - Lifetime
- 1997-08-25 YU YU10499A patent/YU10499A/sh unknown
- 1997-08-25 AT AT97938585T patent/ATE251457T1/de not_active IP Right Cessation
- 1997-08-25 CZ CZ99644A patent/CZ64499A3/cs unknown
-
1999
- 1999-02-23 NO NO990849A patent/NO990849D0/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| WO1998008502A1 (en) | 1998-03-05 |
| YU10499A (sh) | 2001-03-07 |
| HUP9902901A2 (hu) | 2000-05-28 |
| ATE251457T1 (de) | 2003-10-15 |
| AU741324B2 (en) | 2001-11-29 |
| NZ334031A (en) | 2000-07-28 |
| HUP9902901A3 (en) | 2002-01-28 |
| CN1228695A (zh) | 1999-09-15 |
| NO990849L (no) | 1999-02-23 |
| BR9711273A (pt) | 1999-08-17 |
| DE69725459D1 (de) | 2003-11-13 |
| EP0929299A1 (en) | 1999-07-21 |
| JP2000516957A (ja) | 2000-12-19 |
| CA2264267A1 (en) | 1998-03-05 |
| CZ64499A3 (cs) | 1999-05-12 |
| EP0929299B1 (en) | 2003-10-08 |
| UA48245C2 (uk) | 2002-08-15 |
| KR20000035942A (ko) | 2000-06-26 |
| ES2208948T3 (es) | 2004-06-16 |
| EA001912B1 (ru) | 2001-10-22 |
| EA199900241A1 (ru) | 1999-08-26 |
| IL128500A (en) | 2003-06-24 |
| DE69725459T2 (de) | 2004-08-12 |
| AU4088097A (en) | 1998-03-19 |
| PL331882A1 (en) | 1999-08-16 |
| TR199900430T2 (xx) | 1999-06-21 |
| IL128500A0 (en) | 2000-01-31 |
| PT929299E (pt) | 2004-02-27 |
| EP0929299A4 (en) | 2000-12-20 |
| DK0929299T3 (da) | 2004-02-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |