YU10499A - Supstituisani 1,2,3,4-tetrahidro-2-dibenzofuranamini i 2-aminociklohepta /b/benzofurani - Google Patents

Supstituisani 1,2,3,4-tetrahidro-2-dibenzofuranamini i 2-aminociklohepta /b/benzofurani

Info

Publication number
YU10499A
YU10499A YU10499A YU10499A YU10499A YU 10499 A YU10499 A YU 10499A YU 10499 A YU10499 A YU 10499A YU 10499 A YU10499 A YU 10499A YU 10499 A YU10499 A YU 10499A
Authority
YU
Yugoslavia
Prior art keywords
substituted
dibenzofuranamines
aminocyclo
benzofurans
hepta
Prior art date
Application number
YU10499A
Other languages
English (en)
Inventor
Michael Edward Flaugh
Anton Daniel Kiefer
Original Assignee
Eli Lilly And Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly And Company filed Critical Eli Lilly And Company
Publication of YU10499A publication Critical patent/YU10499A/sh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/91—Dibenzofurans; Hydrogenated dibenzofurans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Abstract

Dati pronalazak se odnosi na supstituisane-2-amino-1,2,3,4-tetrahidrobenzofurane i 2-aminociklohepta[b]benzo-furane koji se koriste kao 5-HT1Fagonisti.
YU10499A 1996-08-28 1997-08-25 Supstituisani 1,2,3,4-tetrahidro-2-dibenzofuranamini i 2-aminociklohepta /b/benzofurani YU10499A (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US2474596P 1996-08-28 1996-08-28

Publications (1)

Publication Number Publication Date
YU10499A true YU10499A (sh) 2001-03-07

Family

ID=21822177

Family Applications (1)

Application Number Title Priority Date Filing Date
YU10499A YU10499A (sh) 1996-08-28 1997-08-25 Supstituisani 1,2,3,4-tetrahidro-2-dibenzofuranamini i 2-aminociklohepta /b/benzofurani

Country Status (23)

Country Link
EP (1) EP0929299B1 (sh)
JP (1) JP2000516957A (sh)
KR (1) KR20000035942A (sh)
CN (1) CN1228695A (sh)
AT (1) ATE251457T1 (sh)
AU (1) AU741324B2 (sh)
BR (1) BR9711273A (sh)
CA (1) CA2264267A1 (sh)
CZ (1) CZ64499A3 (sh)
DE (1) DE69725459T2 (sh)
DK (1) DK0929299T3 (sh)
EA (1) EA001912B1 (sh)
ES (1) ES2208948T3 (sh)
HU (1) HUP9902901A3 (sh)
IL (1) IL128500A (sh)
NO (1) NO990849D0 (sh)
NZ (1) NZ334031A (sh)
PL (1) PL331882A1 (sh)
PT (1) PT929299E (sh)
TR (1) TR199900430T2 (sh)
UA (1) UA48245C2 (sh)
WO (1) WO1998008502A1 (sh)
YU (1) YU10499A (sh)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA52778C2 (uk) 1997-10-10 2003-01-15 Янссен Фармацевтика Н.В. Галогенозаміщені тетрациклічні похідні тетрагідрофурану, спосіб їх отримання та композиція на їх основі
TWI263497B (en) 2002-03-29 2006-10-11 Lilly Co Eli Pyridinoylpiperidines as 5-HT1F agonists
JP2006523692A (ja) 2003-04-18 2006-10-19 イーライ リリー アンド カンパニー ５−ｈｔ１ｆ作用薬としての（ピペリジニルオキシ）フェニル、（ピペリジニルオキシ）ピリジニル、（ピペリジニルスルファニル）フェニル、および（ピペリジニルスルファニル）ピリジニル化合物
UA82711C2 (en) 2003-09-12 2008-05-12 Эли Лилли Энд Компани Substituted 2-carbonylamino-6-piperidinaminopyridines and substituted 1-carbonylamino-3-piperidinaminobenzenes as 5-ht1f agonists
CA2549007A1 (en) 2003-12-17 2005-07-07 Eli Lilly And Company Substituted (4-aminocyclohexen-1-yl)phenyl and (4-aminocyclohexen-1-yl)pyridinyl compounds as 5-ht1f agonists
CN1318411C (zh) * 2005-03-21 2007-05-30 中国海洋大学 氢化轮枝霉酮类化合物及其制备方法和用途
CA2795062A1 (en) 2010-04-02 2011-10-06 Colucid Pharmaceuticals, Inc. Compositions and methods of synthesis of pyridinoylpiperidine 5-ht1f agonists
CN102887880B (zh) * 2012-08-20 2014-10-29 东南大学 二苯并呋喃衍生物及其制备方法与用途
AR119319A1 (es) 2019-07-09 2021-12-09 Lilly Co Eli Procesos e intermediario para la preparación a gran escala de hemisuccinato de 2,4,6-trifluoro-n-[6-(1-metil-piperidina-4-carbonil)-piridin-2-il]-benzamida y preparación de acetato de 2,4,6-trifluoro-n-[6-(1-metil-piperidina-4-carbonil)-piridin-2-il]-benzamida

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4668690A (en) * 1985-12-30 1987-05-26 Hoechst Roussel Pharmaceuticals Inc. 1,2,3,4,4a,9b-hexahydro-4a-aminoalkyldibenzofurans useful as analgesics, anticonvulsants or antidepressants
US5521196A (en) * 1994-10-05 1996-05-28 Eli Lilly And Company 5-HT1F agonists for the treatment of migraine
US5698571A (en) * 1994-10-05 1997-12-16 Eli Lilly And Company 5-HT1F mediated inhibition of neurogenic meningeal extravasation: a method for the treatment of migraine

Also Published As

Publication number Publication date
CN1228695A (zh) 1999-09-15
DK0929299T3 (da) 2004-02-16
IL128500A (en) 2003-06-24
DE69725459D1 (de) 2003-11-13
DE69725459T2 (de) 2004-08-12
EA199900241A1 (ru) 1999-08-26
CA2264267A1 (en) 1998-03-05
KR20000035942A (ko) 2000-06-26
TR199900430T2 (xx) 1999-06-21
ES2208948T3 (es) 2004-06-16
PT929299E (pt) 2004-02-27
EP0929299A1 (en) 1999-07-21
NO990849L (no) 1999-02-23
CZ64499A3 (cs) 1999-05-12
JP2000516957A (ja) 2000-12-19
NZ334031A (en) 2000-07-28
ATE251457T1 (de) 2003-10-15
NO990849D0 (no) 1999-02-23
AU741324B2 (en) 2001-11-29
WO1998008502A1 (en) 1998-03-05
EA001912B1 (ru) 2001-10-22
EP0929299B1 (en) 2003-10-08
HUP9902901A3 (en) 2002-01-28
HUP9902901A2 (hu) 2000-05-28
UA48245C2 (uk) 2002-08-15
EP0929299A4 (en) 2000-12-20
IL128500A0 (en) 2000-01-31
AU4088097A (en) 1998-03-19
BR9711273A (pt) 1999-08-17
PL331882A1 (en) 1999-08-16

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