NO983802L - Benzothiofener, formuleringer inneholdende samme og fremgangsmåter - Google Patents

Benzothiofener, formuleringer inneholdende samme og fremgangsmåter

Info

Publication number
NO983802L
NO983802L NO983802A NO983802A NO983802L NO 983802 L NO983802 L NO 983802L NO 983802 A NO983802 A NO 983802A NO 983802 A NO983802 A NO 983802A NO 983802 L NO983802 L NO 983802L
Authority
NO
Norway
Prior art keywords
benzothiophenes
methods
same
formulations containing
present
Prior art date
Application number
NO983802A
Other languages
English (en)
Other versions
NO983802D0 (no
Inventor
George Joseph Cullinan
Alan D Palkowitz
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9604912.7A external-priority patent/GB9604912D0/en
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of NO983802L publication Critical patent/NO983802L/no
Publication of NO983802D0 publication Critical patent/NO983802D0/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/64—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/56—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Abstract

Foreliggende oppfinnelse fremskaffer nye benzothiofenforbindelser.
NO983802A 1996-02-22 1998-08-19 Benzothiofener, formuleringer inneholdende samme og fremgangsmÕter NO983802D0 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1204496P 1996-02-22 1996-02-22
GBGB9604912.7A GB9604912D0 (en) 1996-03-08 1996-03-08 Benzothiophenes, formulations containing same, and methods
PCT/US1997/002464 WO1997030709A1 (en) 1996-02-22 1997-02-19 Benzothiophenes, formulations containing same, and methods

Publications (2)

Publication Number Publication Date
NO983802L true NO983802L (no) 1998-08-19
NO983802D0 NO983802D0 (no) 1998-08-19

Family

ID=26308887

Family Applications (1)

Application Number Title Priority Date Filing Date
NO983802A NO983802D0 (no) 1996-02-22 1998-08-19 Benzothiofener, formuleringer inneholdende samme og fremgangsmÕter

Country Status (23)

Country Link
EP (1) EP0791591B1 (no)
JP (1) JP2000505455A (no)
KR (1) KR19990087091A (no)
CN (1) CN1211921A (no)
AR (2) AR005969A1 (no)
AT (1) ATE204869T1 (no)
AU (1) AU713204B2 (no)
BR (1) BR9707657A (no)
CA (1) CA2246721A1 (no)
CO (1) CO4761064A1 (no)
CZ (1) CZ260798A3 (no)
DE (1) DE69706338T2 (no)
DK (1) DK0791591T3 (no)
EA (1) EA000767B1 (no)
ES (1) ES2162196T3 (no)
IL (1) IL125863A (no)
NO (1) NO983802D0 (no)
NZ (1) NZ331461A (no)
PL (1) PL328832A1 (no)
PT (1) PT791591E (no)
TR (1) TR199801612T2 (no)
WO (1) WO1997030709A1 (no)
YU (1) YU6797A (no)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001517664A (ja) * 1997-09-23 2001-10-09 イーライ・リリー・アンド・カンパニー ベンゾチオフェン類
US6465445B1 (en) 1998-06-11 2002-10-15 Endorecherche, Inc. Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors
US7005428B1 (en) 1998-06-11 2006-02-28 Endorecherche, Inc. Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors
US6060488A (en) * 1998-09-22 2000-05-09 Eli Lilly And Company Benzothiophenes for treating estrogen deficiency
DE60105195T2 (de) * 2000-12-05 2005-09-08 F. Hoffmann-La Roche Ag Benzofuran- und benzothiophen-derivative als selektive cox-2 inhibitoren
CN1668303B (zh) * 2002-07-22 2010-10-27 伊莱利利公司 含苯磺酰基的选择性雌激素受体调节剂
EP1782810A3 (en) * 2002-07-22 2007-05-23 Eli Lilly & Company Selective estrogen receptor modulators containing a phenylsulfonyl group
EP1832582A1 (en) 2002-09-30 2007-09-12 A/S GEA Farmaceutisk Fabrik Novel raloxifene malonic acid addition salts and/or solvates thereof, and pharmaceutical compositions comprising these
CN100348192C (zh) * 2003-02-25 2007-11-14 伊莱利利公司 晶状的非溶剂化1－(4－(2－哌啶基乙氧基)苯氧基)－2－(4－甲磺酰基苯基)－6－羟基萘盐酸化物
WO2005073190A1 (en) * 2004-01-29 2005-08-11 Eli Lilly And Company Selective estrogen receptor modulators
GR1005694B (el) * 2005-06-08 2007-10-22 Αλεξης Μιχαηλ Ιστοειδικα αντιοιστρογονα ειδικα για τον αλφα υποδοχεα των οιστρογονων
CN111018770A (zh) * 2019-12-26 2020-04-17 北京鑫开元医药科技有限公司 一种巴多昔芬氧化物的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH18628A (en) * 1981-04-03 1985-08-23 Lilly Co Eli "6-hydroxy-2-(4-hydroxyphenyl)-3 4-(2- piperidine or 3-methylpyrollidine -benzo b thiophene compounds
US5482949A (en) * 1993-03-19 1996-01-09 Eli Lilly And Company Sulfonate derivatives of 3-aroylbenzo[b]thiophenes
US6756388B1 (en) * 1993-10-12 2004-06-29 Pfizer Inc. Benzothiophenes and related compounds as estrogen agonists
US5510357A (en) * 1995-02-28 1996-04-23 Eli Lilly And Company Benzothiophene compounds as anti-estrogenic agents

Also Published As

Publication number Publication date
CZ260798A3 (cs) 1999-05-12
TR199801612T2 (xx) 1998-11-23
CO4761064A1 (es) 1999-04-27
EP0791591B1 (en) 2001-08-29
ES2162196T3 (es) 2001-12-16
AU2276497A (en) 1997-09-10
PT791591E (pt) 2001-12-28
CN1211921A (zh) 1999-03-24
EA199800753A1 (ru) 1999-02-25
DE69706338D1 (de) 2001-10-04
AR005969A1 (es) 1999-07-21
JP2000505455A (ja) 2000-05-09
NO983802D0 (no) 1998-08-19
KR19990087091A (ko) 1999-12-15
IL125863A (en) 2000-10-31
NZ331461A (en) 1999-05-28
PL328832A1 (en) 1999-02-15
WO1997030709A1 (en) 1997-08-28
ATE204869T1 (de) 2001-09-15
YU6797A (sh) 1999-09-27
BR9707657A (pt) 1999-07-27
DK0791591T3 (da) 2001-10-08
AU713204B2 (en) 1999-11-25
CA2246721A1 (en) 1997-08-28
AR005970A1 (es) 1999-07-21
EP0791591A1 (en) 1997-08-27
DE69706338T2 (de) 2002-06-13
IL125863A0 (en) 1999-04-11
EA000767B1 (ru) 2000-04-24

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