NO985928L - 19Fluor merket antracyklinon og antracyklinderivater - Google Patents

19Fluor merket antracyklinon og antracyklinderivater

Info

Publication number
NO985928L
NO985928L NO985928A NO985928A NO985928L NO 985928 L NO985928 L NO 985928L NO 985928 A NO985928 A NO 985928A NO 985928 A NO985928 A NO 985928A NO 985928 L NO985928 L NO 985928L
Authority
NO
Norway
Prior art keywords
anthracycline
19fluor
labeled
derivatives
anthracycline derivatives
Prior art date
Application number
NO985928A
Other languages
English (en)
Other versions
NO985928D0 (no
NO318194B1 (no
Inventor
Tiziano Bandiera
Daniele Francelli
Michele Caruso
Jacqueline Lansen
Antonino Suarato
Original Assignee
Pharmacia & Upjohn Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Upjohn Spa filed Critical Pharmacia & Upjohn Spa
Publication of NO985928D0 publication Critical patent/NO985928D0/no
Publication of NO985928L publication Critical patent/NO985928L/no
Publication of NO318194B1 publication Critical patent/NO318194B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182Radicals derived from carboxylic acids
    • C07D295/185Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C225/00Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
    • C07C225/24Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones the carbon skeleton containing carbon atoms of quinone rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/10Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
    • C07D295/112Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/22Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
    • C07D295/26Sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/24Condensed ring systems having three or more rings
    • C07H15/252Naphthacene radicals, e.g. daunomycins, adriamycins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00Systems containing at least three condensed rings
    • C07C2603/02Ortho- or ortho- and peri-condensed systems
    • C07C2603/40Ortho- or ortho- and peri-condensed systems containing four condensed rings
    • C07C2603/42Ortho- or ortho- and peri-condensed systems containing four condensed rings containing only six-membered rings
    • C07C2603/44Naphthacenes; Hydrogenated naphthacenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Radiology & Medical Imaging (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Neurology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Psychiatry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Immunology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
NO19985928A 1996-06-26 1998-12-17 <O>19</O>Fluor merket antracyklinon og antracyklinderivater anvendelse av samme samt farmasoytisk sammensetning inneholdende samme NO318194B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9613433.3A GB9613433D0 (en) 1996-06-26 1996-06-26 Fluoro labelled anthracyclinone and anthracycline derivatives
PCT/EP1997/003234 WO1997049433A1 (en) 1996-06-26 1997-06-18 Fluoro labelled anthracyclinone and anthracycline derivatives

Publications (3)

Publication Number Publication Date
NO985928D0 NO985928D0 (no) 1998-12-17
NO985928L true NO985928L (no) 1998-12-17
NO318194B1 NO318194B1 (no) 2005-02-14

Family

ID=10795944

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19985928A NO318194B1 (no) 1996-06-26 1998-12-17 <O>19</O>Fluor merket antracyklinon og antracyklinderivater anvendelse av samme samt farmasoytisk sammensetning inneholdende samme

Country Status (22)

Country Link
US (1) US6103700A (no)
EP (1) EP0910415B1 (no)
JP (1) JP2000514784A (no)
KR (1) KR100451685B1 (no)
CN (1) CN1263514C (no)
AR (1) AR008616A1 (no)
AT (1) ATE266427T1 (no)
AU (1) AU726935B2 (no)
BR (1) BR9710857A (no)
CA (1) CA2258630A1 (no)
DE (1) DE69729092D1 (no)
EA (1) EA002203B1 (no)
GB (1) GB9613433D0 (no)
HU (1) HUP9903651A3 (no)
IL (1) IL127465A (no)
NO (1) NO318194B1 (no)
NZ (1) NZ333660A (no)
PL (1) PL190149B1 (no)
TW (1) TW494099B (no)
UA (1) UA66344C2 (no)
WO (1) WO1997049433A1 (no)
ZA (1) ZA975629B (no)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9805082D0 (en) * 1998-03-10 1998-05-06 Pharmacia & Upjohn Spa Heterocyclyl anthracyclinone derivatives
GB9805080D0 (en) * 1998-03-10 1998-05-06 Pharmacia & Upjohn Spa Amino anthracyclinone derivatives
US6589504B1 (en) 2000-09-22 2003-07-08 Pharmacia & Upjohn Company Compounds and methods for diagnosing and treating amyloid-related conditions
US6828347B2 (en) 2002-11-06 2004-12-07 Illinois Institute Of Technology Anti-viral multi-quinone compounds and regiospecific synthesis thereof
EP2584369A1 (en) * 2011-10-17 2013-04-24 Koninklijke Philips Electronics N.V. Magnetic field probe for MRI with a fluoroelastomer or a solution of a fluorine-containing compound

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1573037A (en) * 1977-05-05 1980-08-13 Farmaceutici Italia Anthracyclines
GB1573036A (en) * 1977-05-05 1980-08-13 Farmaceutici Italia Anthracyclines
US4345070A (en) * 1980-09-29 1982-08-17 Farmitalia Carlo Erba S.P.A. Process for the preparation of 4'-deoxy-daunorubicin and 4'-deoxy-doxorubicin
GB9114549D0 (en) * 1991-07-05 1991-08-21 Erba Carlo Spa Mono and bis alkylamino-anthracyclines
GB9416007D0 (en) * 1994-08-08 1994-09-28 Erba Carlo Spa Anthracyclinone derivatives
GB9418260D0 (en) * 1994-09-09 1994-10-26 Erba Carlo Spa Anthracycline derivatives
WO1997016191A1 (en) * 1995-11-02 1997-05-09 Warner-Lambert Company Inhibition of amyloidosis by 9-acridinones

Also Published As

Publication number Publication date
PL330907A1 (en) 1999-06-07
US6103700A (en) 2000-08-15
KR100451685B1 (ko) 2004-12-30
HUP9903651A2 (hu) 2000-03-28
EP0910415A1 (en) 1999-04-28
ZA975629B (en) 1998-01-30
PL190149B1 (pl) 2005-11-30
CN1223592A (zh) 1999-07-21
AR008616A1 (es) 2000-02-09
IL127465A0 (en) 1999-10-28
UA66344C2 (en) 2004-05-17
KR20000022236A (ko) 2000-04-25
NZ333660A (en) 2000-07-28
EP0910415B1 (en) 2004-05-12
NO985928D0 (no) 1998-12-17
IL127465A (en) 2005-11-20
AU3262297A (en) 1998-01-14
EA002203B1 (ru) 2002-02-28
WO1997049433A1 (en) 1997-12-31
HUP9903651A3 (en) 2000-05-29
BR9710857A (pt) 1999-08-17
NO318194B1 (no) 2005-02-14
AU726935B2 (en) 2000-11-23
DE69729092D1 (de) 2004-06-17
CN1263514C (zh) 2006-07-12
GB9613433D0 (en) 1996-08-28
ATE266427T1 (de) 2004-05-15
EA199900054A1 (ru) 1999-06-24
JP2000514784A (ja) 2000-11-07
TW494099B (en) 2002-07-11
CA2258630A1 (en) 1997-12-31

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