NO984740D0 - Isatinderivater som acetylcholinesteraseinhibitorer og analgetiske midler - Google Patents

Isatinderivater som acetylcholinesteraseinhibitorer og analgetiske midler

Info

Publication number
NO984740D0
NO984740D0 NO984740A NO984740A NO984740D0 NO 984740 D0 NO984740 D0 NO 984740D0 NO 984740 A NO984740 A NO 984740A NO 984740 A NO984740 A NO 984740A NO 984740 D0 NO984740 D0 NO 984740D0
Authority
NO
Norway
Prior art keywords
analgesics
acetylcholinesterase inhibitors
isatin derivatives
isatin
derivatives
Prior art date
Application number
NO984740A
Other languages
English (en)
Norwegian (no)
Other versions
NO984740L (no
Inventor
Stephen James Shimshock
Abdul Ezaz Mutlib
Susan Marie Chesson
Original Assignee
Hoechst Marion Roussel Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel Inc
Publication of NO984740L publication Critical patent/NO984740L/no
Publication of NO984740D0 publication Critical patent/NO984740D0/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
NO984740A 1996-04-12 1998-10-09 Isatinderivater som acetylcholinesteraseinhibitorer og analgetiske midler NO984740D0 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US63187096A 1996-04-12 1996-04-12
PCT/US1997/003598 WO1997038993A1 (en) 1996-04-12 1997-03-07 Isatin derivatives as acetylcholinesterase inhibitors and analgesics

Publications (2)

Publication Number Publication Date
NO984740L NO984740L (no) 1998-10-09
NO984740D0 true NO984740D0 (no) 1998-10-09

Family

ID=24533114

Family Applications (1)

Application Number Title Priority Date Filing Date
NO984740A NO984740D0 (no) 1996-04-12 1998-10-09 Isatinderivater som acetylcholinesteraseinhibitorer og analgetiske midler

Country Status (19)

Country Link
EP (1) EP0892796B1 (ja)
JP (1) JP4109718B2 (ja)
KR (1) KR20000005379A (ja)
CN (1) CN1215399A (ja)
AR (1) AR006606A1 (ja)
AT (1) ATE207483T1 (ja)
BR (1) BR9708655A (ja)
CA (1) CA2252039C (ja)
DE (1) DE69707659T2 (ja)
DK (1) DK0892796T3 (ja)
ES (1) ES2165586T3 (ja)
GR (1) GR3037006T3 (ja)
HU (1) HUP9903473A3 (ja)
IL (1) IL126308A0 (ja)
NO (1) NO984740D0 (ja)
PT (1) PT892796E (ja)
TW (1) TW426678B (ja)
WO (1) WO1997038993A1 (ja)
ZA (1) ZA972990B (ja)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6218383B1 (en) 1998-08-07 2001-04-17 Targacept, Inc. Pharmaceutical compositions for the prevention and treatment of central nervous system disorders
JP5379692B2 (ja) 2006-11-09 2013-12-25 プロビオドルグ エージー 潰瘍、癌及び他の疾患の治療のためのグルタミニルシクラーゼの阻害薬としての3−ヒドロキシ−1,5−ジヒドロ−ピロール−2−オン誘導体
JP5523107B2 (ja) 2006-11-30 2014-06-18 プロビオドルグ エージー グルタミニルシクラーゼの新規阻害剤
ZA200905537B (en) 2007-03-01 2010-10-27 Probiodrug Ag New use of glutaminyl cyclase inhibitors
ES2533484T3 (es) 2007-04-18 2015-04-10 Probiodrug Ag Derivados de tiourea como inhibidores de la glutaminil ciclasa
EA022007B1 (ru) 2009-09-11 2015-10-30 Пробиодруг Аг Гетероциклические производные в качестве ингибиторов глутаминилциклазы
JP6082250B2 (ja) 2010-02-09 2017-02-15 ザ・ジョンズ・ホプキンス・ユニバーシティー 認知機能を改善するための方法および組成物
CN102762554A (zh) 2010-02-16 2012-10-31 辉瑞大药厂 5-ht4受体的部分激动剂(r)-4-((4-((4-(四氢呋喃-3-基氧基)苯并[d]异*唑-3-基氧基)甲基)哌啶-1-基)甲基)四氢-2h-吡喃-4-醇
JP6026284B2 (ja) 2010-03-03 2016-11-16 プロビオドルグ エージー グルタミニルシクラーゼの阻害剤
KR101790806B1 (ko) 2010-03-10 2017-11-20 프로비오드룩 아게 글루타미닐 사이클라제(qc, ec 2.3.2.5)의 헤테로사이클릭 억제제
EP2560953B1 (en) 2010-04-21 2016-01-06 Probiodrug AG Inhibitors of glutaminyl cyclase
WO2012123563A1 (en) 2011-03-16 2012-09-20 Probiodrug Ag Benz imidazole derivatives as inhibitors of glutaminyl cyclase
CA2891122C (en) 2012-11-14 2021-07-20 The Johns Hopkins University Methods and compositions for treating schizophrenia
ES2663680T3 (es) 2012-12-13 2018-04-16 H. Lundbeck A/S Composiciones que comprenden vortioxetina y donepezilo
WO2014144663A1 (en) 2013-03-15 2014-09-18 The Johns Hopkins University Methods and compositions for improving cognitive function
CN105142623A (zh) 2013-03-15 2015-12-09 艾吉因生物股份有限公司 用于改善认知功能的方法和组合物
US10537552B2 (en) 2015-05-05 2020-01-21 Carafe Drug Innovation, Llc Substituted 5-hydroxyoxindoles and their use as analgesics and fever reducers
NZ738682A (en) 2015-05-22 2022-01-28 Agenebio Inc Extended release pharmaceutical compositions of levetiracetam
PL3461819T3 (pl) 2017-09-29 2020-11-30 Probiodrug Ag Inhibitory cyklazy glutaminylowej

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4994472A (en) * 1989-08-02 1991-02-19 Hoechst-Roussel Pharmaceuticals Incorporated 1-(pyridinylamino)-2-pyrrolidinones as pain relievers
US5296488A (en) * 1989-08-02 1994-03-22 Hoechst-Roussel Pharmaceuticals Inc. Method of using 2,3-dihydro-1-(pyridinylamino)-indoles as anticonvulsants and for the enhancement of memory
US5006537A (en) * 1989-08-02 1991-04-09 Hoechst-Roussel Pharmaceuticals, Inc. 1,3-dihydro-1-(pyridinylamino)-2H-indol-2-ones

Also Published As

Publication number Publication date
CN1215399A (zh) 1999-04-28
ES2165586T3 (es) 2002-03-16
JP4109718B2 (ja) 2008-07-02
NO984740L (no) 1998-10-09
DK0892796T3 (da) 2001-11-19
CA2252039C (en) 2002-12-24
ZA972990B (en) 1997-11-03
WO1997038993A1 (en) 1997-10-23
KR20000005379A (en) 2000-01-25
AU2072597A (en) 1997-11-07
CA2252039A1 (en) 1997-10-23
PT892796E (pt) 2002-03-28
EP0892796A1 (en) 1999-01-27
JP2001508400A (ja) 2001-06-26
AU716997B2 (en) 2000-03-16
AR006606A1 (es) 1999-09-08
IL126308A0 (en) 1999-05-09
GR3037006T3 (en) 2002-01-31
HUP9903473A3 (en) 2000-09-28
HUP9903473A2 (hu) 2000-05-28
EP0892796B1 (en) 2001-10-24
ATE207483T1 (de) 2001-11-15
DE69707659T2 (de) 2002-05-08
DE69707659D1 (de) 2001-11-29
BR9708655A (pt) 1999-08-03
TW426678B (en) 2001-03-21

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