NO984263L - Indolomorfinan-derivat og middel for herding og forebygging av cerebral forstyrrelse - Google Patents
Indolomorfinan-derivat og middel for herding og forebygging av cerebral forstyrrelseInfo
- Publication number
- NO984263L NO984263L NO984263A NO984263A NO984263L NO 984263 L NO984263 L NO 984263L NO 984263 A NO984263 A NO 984263A NO 984263 A NO984263 A NO 984263A NO 984263 L NO984263 L NO 984263L
- Authority
- NO
- Norway
- Prior art keywords
- cerebral
- preventing
- present
- derivative
- diseases
- Prior art date
Links
- 206010008129 cerebral palsy Diseases 0.000 title 1
- 230000002265 prevention Effects 0.000 title 1
- 208000018152 Cerebral disease Diseases 0.000 abstract 4
- 230000002490 cerebral effect Effects 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 2
- -1 hydroxy, methoxy Chemical group 0.000 abstract 2
- 210000002569 neuron Anatomy 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 230000000472 traumatic effect Effects 0.000 abstract 2
- 206010048962 Brain oedema Diseases 0.000 abstract 1
- 206010056677 Nerve degeneration Diseases 0.000 abstract 1
- 208000006011 Stroke Diseases 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000005605 benzo group Chemical group 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 208000006752 brain edema Diseases 0.000 abstract 1
- 208000029028 brain injury Diseases 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 125000004186 cyclopropylmethyl group Chemical group [H]C([H])(*)C1([H])C([H])([H])C1([H])[H] 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000002008 hemorrhagic effect Effects 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 230000000302 ischemic effect Effects 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 230000004770 neurodegeneration Effects 0.000 abstract 1
- 208000015122 neurodegenerative disease Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP582997 | 1997-01-16 | ||
| PCT/JP1998/000092 WO1998031684A1 (en) | 1997-01-16 | 1998-01-13 | Indolomorphinane derivatives and remedies/preventives for cerebral disorders |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO984263D0 NO984263D0 (no) | 1998-09-15 |
| NO984263L true NO984263L (no) | 1998-11-13 |
Family
ID=11621945
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO984263A NO984263L (no) | 1997-01-16 | 1998-09-15 | Indolomorfinan-derivat og middel for herding og forebygging av cerebral forstyrrelse |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6156762A (de) |
| EP (1) | EP0894799B1 (de) |
| JP (1) | JP4110579B2 (de) |
| KR (1) | KR100557804B1 (de) |
| CN (1) | CN1117754C (de) |
| AT (1) | ATE263769T1 (de) |
| AU (1) | AU739367B2 (de) |
| DE (1) | DE69822937T2 (de) |
| ES (1) | ES2217533T3 (de) |
| NO (1) | NO984263L (de) |
| NZ (1) | NZ331769A (de) |
| WO (1) | WO1998031684A1 (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19939044A1 (de) * | 1999-08-18 | 2001-03-15 | Gruenenthal Gmbh | Verwendung von Morphinanderivaten als Arzneimittel |
| CN1204139C (zh) * | 1999-08-24 | 2005-06-01 | 东丽株式会社 | 神经性疼痛治疗剂 |
| US6809104B2 (en) | 2001-05-04 | 2004-10-26 | Tularik Inc. | Fused heterocyclic compounds |
| ATE422887T1 (de) | 2001-05-04 | 2009-03-15 | Amgen Inc | Kondensierte heterozyklische verbindungen |
| US7253179B2 (en) | 2002-11-06 | 2007-08-07 | Amgen Inc. | Fused heterocyclic compounds |
| US20100172909A1 (en) * | 2005-10-24 | 2010-07-08 | Masahiro Nishibori | Cerebral edema suppressant |
| US8829020B2 (en) | 2009-07-16 | 2014-09-09 | Mallinckrodt Llc | Compounds and compositions for use in phototherapy and in treatment of ocular neovascular disease and cancers |
| JPWO2016167318A1 (ja) * | 2015-04-16 | 2018-02-08 | 学校法人北里研究所 | 記憶改善剤及びその使用 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4680172A (en) * | 1985-03-05 | 1987-07-14 | Ciba-Geigy Corporation | Devices and methods for treating memory impairment |
| US4816586A (en) * | 1987-07-29 | 1989-03-28 | Regents Of The University Of Minnesota | Delta opioid receptor antagonists |
| JPH03218313A (ja) * | 1989-11-22 | 1991-09-25 | Toray Ind Inc | 脳細胞保護剤 |
| JP2906654B2 (ja) * | 1989-11-28 | 1999-06-21 | 東レ株式会社 | 免疫抑制剤及びその製造方法 |
| US5223507A (en) * | 1992-01-21 | 1993-06-29 | G. D. Searle & Co. | Method of using opioid compounds as delta opioid selective agonist analgesics |
| US5225417A (en) * | 1992-01-21 | 1993-07-06 | G. D. Searle & Co. | Opioid agonist compounds |
| US5852030A (en) * | 1992-09-29 | 1998-12-22 | Toray Industries, Inc. | Indole derivatives, process for producing the same and medicinal uses of the same |
| CN1043766C (zh) * | 1992-09-29 | 1999-06-23 | 东丽株式会社 | 吲哚衍生物及其制法和它们在制备药物中的应用 |
| KR950700065A (ko) * | 1992-12-22 | 1995-01-16 | 마에다 카쭈노수케 | 진해제(Antitussive) |
| KR100341950B1 (ko) * | 1993-07-19 | 2002-11-29 | 도레이 가부시끼가이샤 | 뇌세포보호제 |
| AU686203B2 (en) * | 1993-07-23 | 1998-02-05 | Toray Industries, Inc. | Morphinan derivative and medicinal use |
| SE9401727D0 (sv) * | 1994-05-18 | 1994-05-18 | Astra Ab | New compounds I |
| SE9401728D0 (sv) * | 1994-05-18 | 1994-05-18 | Astra Ab | New compounds II |
-
1998
- 1998-01-13 ES ES98900228T patent/ES2217533T3/es not_active Expired - Lifetime
- 1998-01-13 EP EP98900228A patent/EP0894799B1/de not_active Expired - Lifetime
- 1998-01-13 KR KR1019980707314A patent/KR100557804B1/ko not_active Expired - Fee Related
- 1998-01-13 WO PCT/JP1998/000092 patent/WO1998031684A1/ja not_active Ceased
- 1998-01-13 DE DE69822937T patent/DE69822937T2/de not_active Expired - Fee Related
- 1998-01-13 AU AU53437/98A patent/AU739367B2/en not_active Ceased
- 1998-01-13 US US09/142,794 patent/US6156762A/en not_active Expired - Fee Related
- 1998-01-13 NZ NZ331769A patent/NZ331769A/xx unknown
- 1998-01-13 AT AT98900228T patent/ATE263769T1/de not_active IP Right Cessation
- 1998-01-13 JP JP53410198A patent/JP4110579B2/ja not_active Expired - Fee Related
- 1998-01-13 CN CN98800291A patent/CN1117754C/zh not_active Expired - Fee Related
- 1998-09-15 NO NO984263A patent/NO984263L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CN1220668A (zh) | 1999-06-23 |
| NO984263D0 (no) | 1998-09-15 |
| CN1117754C (zh) | 2003-08-13 |
| EP0894799A4 (de) | 2001-08-16 |
| JP4110579B2 (ja) | 2008-07-02 |
| EP0894799A1 (de) | 1999-02-03 |
| WO1998031684A1 (en) | 1998-07-23 |
| AU739367B2 (en) | 2001-10-11 |
| DE69822937T2 (de) | 2004-08-12 |
| KR20000064618A (ko) | 2000-11-06 |
| DE69822937D1 (de) | 2004-05-13 |
| AU5343798A (en) | 1998-08-07 |
| KR100557804B1 (ko) | 2006-06-20 |
| ATE263769T1 (de) | 2004-04-15 |
| EP0894799B1 (de) | 2004-04-07 |
| US6156762A (en) | 2000-12-05 |
| ES2217533T3 (es) | 2004-11-01 |
| NZ331769A (en) | 2000-05-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |