NO983919L - 7-fenyl-1,4-diazepanderivater, fremgangsmÕter for fremstilling av disse samt legemidler inneholdende slike forbindelser - Google Patents
7-fenyl-1,4-diazepanderivater, fremgangsmÕter for fremstilling av disse samt legemidler inneholdende slike forbindelserInfo
- Publication number
- NO983919L NO983919L NO983919A NO983919A NO983919L NO 983919 L NO983919 L NO 983919L NO 983919 A NO983919 A NO 983919A NO 983919 A NO983919 A NO 983919A NO 983919 L NO983919 L NO 983919L
- Authority
- NO
- Norway
- Prior art keywords
- lower alkyl
- trifluoromethyl
- halogen
- represents hydrogen
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/08—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 not condensed with other rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Abstract
Neurokinin-antagonistisk aktive forbindelser generell formel I, hvori R1 betegner hydrogen eller lavere alkyl, R2 betegner hydrogen, lavere alkyl, lavere alkoksy, halogen eller trifluormetyl, og R3 betegner hydrogen, lavere alkyl, lavere alkoksy, halogen eller trifluormetyl, eller R2 og R3 betegner sammen alkylendioksy med l til 2 karbonatomer bundet til nabokarbonatomer på fenyl- ringen, R' betegner hydrogen, lavere alkyl, lavere alkoksy, halogen eller trifluormetyl, og R5 betegner hydrogen, lavere alkyl, lavere alkoksy, halogen eller trifluormetyl, eller R4 og R5 betegner sammen alkylendioksy med l til 2 karbonatomer bundet til nabokarbonatomet på fenyl- ringen, K6 betegner lavere alkyl, halogen eller trifluormetyl, R7 betegner lavere alkyl, halogen eller trifluormetyl, A betegner en -(CH2)n-gruppe, hvori n betegner et helt tall fra l til 3, eller en -NH-(CH2)B- gruppe, hvori m betegner et helt tall fra 2 til 3, og B betegner en alkylenkjede med l til 3 karbonatomer som eventuelt er substituert med lavere alkyl, så vel som deres fysiologisk forenlige salter samt fremgangsmåter for frem- stilling av disse forbindelser.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19737334A DE19737334A1 (de) | 1997-08-27 | 1997-08-27 | 7-Phenyl-1,4-diazepan-Derivate, sowie Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel |
Publications (2)
Publication Number | Publication Date |
---|---|
NO983919D0 NO983919D0 (no) | 1998-08-26 |
NO983919L true NO983919L (no) | 1999-03-01 |
Family
ID=7840336
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO983919A NO983919L (no) | 1997-08-27 | 1998-08-26 | 7-fenyl-1,4-diazepanderivater, fremgangsmÕter for fremstilling av disse samt legemidler inneholdende slike forbindelser |
Country Status (21)
Country | Link |
---|---|
US (1) | US6040303A (no) |
EP (1) | EP0899264B1 (no) |
JP (1) | JP4380814B2 (no) |
KR (1) | KR19990023606A (no) |
CN (1) | CN1220262A (no) |
AR (1) | AR009899A1 (no) |
AT (1) | ATE310732T1 (no) |
AU (1) | AU8190098A (no) |
BR (1) | BR9803250A (no) |
CA (1) | CA2245926C (no) |
CZ (1) | CZ267298A3 (no) |
DE (2) | DE19737334A1 (no) |
HU (1) | HUP9801888A3 (no) |
ID (1) | ID20786A (no) |
IL (1) | IL125886A0 (no) |
NO (1) | NO983919L (no) |
NZ (1) | NZ331523A (no) |
PL (1) | PL328222A1 (no) |
SK (1) | SK111798A3 (no) |
TR (1) | TR199801681A2 (no) |
ZA (1) | ZA986719B (no) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0108595D0 (en) | 2001-04-05 | 2001-05-23 | Glaxo Group Ltd | Chemical compounds |
KR100699886B1 (ko) * | 2005-12-21 | 2007-03-28 | 삼성전자주식회사 | 하드디스크 드라이브의 스핀들 모터-디스크 조립체 및 이의조립방법 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2328870C2 (de) * | 1973-06-06 | 1982-04-08 | Vsesojuznyj naučno-issledovatel'skij chimiko-farmacevtičeskij institut imeni Sergo Ordžonikidze, Moskva | N,N'-Di-(β-brompropionyl)-hexahydro-1,4-diazepin und Verfahren zu seiner Herstellung |
DE3702755A1 (de) * | 1987-01-30 | 1988-08-11 | Hoechst Ag | 3,5-di-tert.-butyl-4-hydroxybenzoesaeureamid, verschiedene von dessen derivaten, verfahren zur herstellung dieser verbindungen, die sie enthaltenden arzneimittel und ihre verwendung |
JP2732003B2 (ja) * | 1992-11-17 | 1998-03-25 | 富士写真フイルム株式会社 | 2,6−ジアルコキシ−4−カルバモイルフェノ−ル誘導体及び抗酸化剤組成物 |
JPH07145060A (ja) * | 1993-11-25 | 1995-06-06 | Teijin Ltd | 細胞遊走阻害剤 |
IL111730A (en) * | 1993-11-29 | 1998-12-06 | Fujisawa Pharmaceutical Co | Piperazine derivatives, processes for their preparation and pharmaceutical preparations containing them |
US5795894A (en) * | 1995-05-02 | 1998-08-18 | Schering Corporation | Piperazino derivatives as neurokinn antagonists |
US5719156A (en) * | 1995-05-02 | 1998-02-17 | Schering Corporation | Piperazino derivatives as neurokinin antagonists |
CZ342397A3 (cs) * | 1995-05-02 | 1998-03-18 | Schering Corporation | Piperazinové deriváty jako antagonisté neurokininu |
-
1997
- 1997-08-27 DE DE19737334A patent/DE19737334A1/de not_active Withdrawn
-
1998
- 1998-07-28 ZA ZA986719A patent/ZA986719B/xx unknown
- 1998-08-10 AR ARP980103946A patent/AR009899A1/es unknown
- 1998-08-14 SK SK1117-98A patent/SK111798A3/sk unknown
- 1998-08-14 KR KR1019980033039A patent/KR19990023606A/ko not_active Application Discontinuation
- 1998-08-17 HU HU9801888A patent/HUP9801888A3/hu unknown
- 1998-08-20 DE DE59813212T patent/DE59813212D1/de not_active Expired - Lifetime
- 1998-08-20 AT AT98115651T patent/ATE310732T1/de not_active IP Right Cessation
- 1998-08-20 EP EP98115651A patent/EP0899264B1/de not_active Expired - Lifetime
- 1998-08-21 CZ CZ982672A patent/CZ267298A3/cs unknown
- 1998-08-21 IL IL12588698A patent/IL125886A0/xx unknown
- 1998-08-24 NZ NZ331523A patent/NZ331523A/en unknown
- 1998-08-24 JP JP23712998A patent/JP4380814B2/ja not_active Expired - Lifetime
- 1998-08-26 PL PL98328222A patent/PL328222A1/xx unknown
- 1998-08-26 NO NO983919A patent/NO983919L/no not_active Application Discontinuation
- 1998-08-26 CA CA002245926A patent/CA2245926C/en not_active Expired - Fee Related
- 1998-08-26 AU AU81900/98A patent/AU8190098A/en not_active Abandoned
- 1998-08-27 ID IDP981172A patent/ID20786A/id unknown
- 1998-08-27 BR BR9803250-0A patent/BR9803250A/pt not_active Application Discontinuation
- 1998-08-27 CN CN98118497A patent/CN1220262A/zh active Pending
- 1998-08-27 US US09/141,312 patent/US6040303A/en not_active Expired - Lifetime
- 1998-08-27 TR TR1998/01681A patent/TR199801681A2/xx unknown
Also Published As
Publication number | Publication date |
---|---|
AR009899A1 (es) | 2000-05-03 |
CA2245926C (en) | 2006-12-12 |
PL328222A1 (en) | 1999-03-01 |
ZA986719B (en) | 1999-02-02 |
SK111798A3 (en) | 1999-05-07 |
NZ331523A (en) | 2000-02-28 |
ATE310732T1 (de) | 2005-12-15 |
EP0899264A1 (de) | 1999-03-03 |
KR19990023606A (ko) | 1999-03-25 |
DE19737334A1 (de) | 1999-03-04 |
CN1220262A (zh) | 1999-06-23 |
ID20786A (id) | 1999-03-04 |
CZ267298A3 (cs) | 1999-03-17 |
US6040303A (en) | 2000-03-21 |
JP4380814B2 (ja) | 2009-12-09 |
HU9801888D0 (en) | 1998-10-28 |
HUP9801888A3 (en) | 1999-06-28 |
IL125886A0 (en) | 1999-04-11 |
JPH11116557A (ja) | 1999-04-27 |
TR199801681A3 (tr) | 1999-03-22 |
NO983919D0 (no) | 1998-08-26 |
AU8190098A (en) | 1999-03-11 |
BR9803250A (pt) | 2000-02-08 |
TR199801681A2 (xx) | 1999-03-22 |
EP0899264B1 (de) | 2005-11-23 |
HUP9801888A2 (hu) | 1999-05-28 |
DE59813212D1 (de) | 2005-12-29 |
CA2245926A1 (en) | 1999-02-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |