NO983860L - Nye triazolopuriner, fremgangsmÕte for deres fremstilling og deres anvendelse som legemidler - Google Patents
Nye triazolopuriner, fremgangsmÕte for deres fremstilling og deres anvendelse som legemidlerInfo
- Publication number
- NO983860L NO983860L NO983860A NO983860A NO983860L NO 983860 L NO983860 L NO 983860L NO 983860 A NO983860 A NO 983860A NO 983860 A NO983860 A NO 983860A NO 983860 L NO983860 L NO 983860L
- Authority
- NO
- Norway
- Prior art keywords
- triazolopurins
- drugs
- novel
- preparation
- receptors
- Prior art date
Links
- 239000003814 drug Substances 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 102000009346 Adenosine receptors Human genes 0.000 abstract 2
- 108050000203 Adenosine receptors Proteins 0.000 abstract 2
- 230000004913 activation Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000001575 pathological effect Effects 0.000 abstract 1
- 239000000296 purinergic P1 receptor antagonist Substances 0.000 abstract 1
- 102000005962 receptors Human genes 0.000 abstract 1
- 108020003175 receptors Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/36—Antigestagens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Diabetes (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Psychiatry (AREA)
- Urology & Nephrology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19629378A DE19629378A1 (de) | 1996-07-20 | 1996-07-20 | Neue Triazolopurine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
| PCT/EP1997/003841 WO1998003511A1 (de) | 1996-07-20 | 1997-07-17 | Neue triazolopurine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| CA002242097A CA2242097C (en) | 1996-07-20 | 1998-06-26 | Imidazotriazolopyrimidines, process for preparing them and their use as pharmaceutical compositions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO983860D0 NO983860D0 (no) | 1998-08-21 |
| NO983860L true NO983860L (no) | 1998-10-21 |
Family
ID=32963000
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO983860A NO983860L (no) | 1996-07-20 | 1998-08-21 | Nye triazolopuriner, fremgangsmÕte for deres fremstilling og deres anvendelse som legemidler |
Country Status (25)
| Country | Link |
|---|---|
| EP (2) | EP0880524B1 (id) |
| JP (1) | JP3020281B2 (id) |
| CN (1) | CN1219936A (id) |
| AT (1) | ATE191913T1 (id) |
| AU (1) | AU3695597A (id) |
| BG (1) | BG102707A (id) |
| BR (1) | BR9710747A (id) |
| CA (1) | CA2256736A1 (id) |
| CZ (1) | CZ265498A3 (id) |
| DE (2) | DE19629378A1 (id) |
| DK (1) | DK0880524T3 (id) |
| EE (1) | EE9800451A (id) |
| ES (1) | ES2147453T3 (id) |
| GR (1) | GR3033842T3 (id) |
| HR (1) | HRP970395A2 (id) |
| HU (1) | HUP9902311A3 (id) |
| ID (1) | ID19106A (id) |
| IL (1) | IL126453A0 (id) |
| NO (1) | NO983860L (id) |
| PL (1) | PL328824A1 (id) |
| PT (1) | PT880524E (id) |
| SK (1) | SK114498A3 (id) |
| TR (1) | TR199801659T2 (id) |
| WO (1) | WO1998003511A1 (id) |
| ZA (1) | ZA976331B (id) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19826843A1 (de) * | 1998-06-16 | 1999-12-23 | Boehringer Ingelheim Pharma | Neue Imidazotriazolopyrimidine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
| US6492377B1 (en) | 1998-06-25 | 2002-12-10 | Boehringer Ingelheim Pharma Kg | Imidazotriazolopyrimidines with adenosine-antagonistic activity |
| AU9347498A (en) * | 1998-08-27 | 2000-03-21 | Boehringer Ingelheim Pharma Kg | Imidazotriazolopyrimidines |
| WO2004075846A2 (en) | 2003-02-25 | 2004-09-10 | Bristol-Myers Squibb Company | Pyrazolopurine-based tricyclic compounds and pharmaceutical compositions comprising same |
| US7071333B2 (en) | 2003-07-30 | 2006-07-04 | Bristol-Myers Squibb Company | Triazolopurine-based tricyclic compounds and pharmaceutical compositions comprising same |
| KR20090025261A (ko) | 2006-06-23 | 2009-03-10 | 인사이트 코포레이션 | Ｈｍ７４ａ 아고니스트로서의 퓨리논 유도체 |
| WO2019168847A1 (en) | 2018-02-27 | 2019-09-06 | Incyte Corporation | Imidazopyrimidines and triazolopyrimidines as a2a / a2b inhibitors |
| EP3810610A1 (en) | 2018-05-18 | 2021-04-28 | Incyte Corporation | Fused pyrimidine derivatives as a2a / a2b inhibitors |
| KR20210049090A (ko) | 2018-07-05 | 2021-05-04 | 인사이트 코포레이션 | A2a/a2b 억제제로서 융합된 피라진 유도체 |
| CA3120862C (en) | 2018-11-30 | 2024-05-07 | Merck Sharp & Dohme Corp. | 9-substituted amino triazolo quinazoline derivatives as adenosine receptor antagonists, pharmaceutical compositions and their use |
| TWI829857B (zh) | 2019-01-29 | 2024-01-21 | 美商英塞特公司 | 作為a2a / a2b抑制劑之吡唑并吡啶及三唑并吡啶 |
| CN112778311B (zh) * | 2019-11-01 | 2024-06-04 | 上海翰森生物医药科技有限公司 | 含氮并环类衍生物抑制剂、其制备方法和应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA902282B (en) * | 1989-03-29 | 1990-12-28 | Merrell Dow Pharma | Selective adenosine receptor compounds |
| IT1264901B1 (it) * | 1993-06-29 | 1996-10-17 | Schering Plough S P A | Analoghi eterociclici di 1,2,4-triazolo(15-c)pirimidine ad attivita' antagonista per il recettore a2 dell'adenosina |
| JPH083169A (ja) * | 1994-06-15 | 1996-01-09 | Yamasa Shoyu Co Ltd | ４−メチル−１Ｈ−［１，２，４］トリアゾロ［１，５−ａ］プリン−９（４Ｈ）−オン類 |
-
1996
- 1996-07-20 DE DE19629378A patent/DE19629378A1/de not_active Withdrawn
-
1997
- 1997-07-17 TR TR1998/01659T patent/TR199801659T2/xx unknown
- 1997-07-17 CA CA002256736A patent/CA2256736A1/en not_active Abandoned
- 1997-07-17 PT PT97933683T patent/PT880524E/pt unknown
- 1997-07-17 DE DE59701467T patent/DE59701467D1/de not_active Expired - Lifetime
- 1997-07-17 EE EE9800451A patent/EE9800451A/xx unknown
- 1997-07-17 EP EP97933683A patent/EP0880524B1/de not_active Expired - Lifetime
- 1997-07-17 WO PCT/EP1997/003841 patent/WO1998003511A1/de not_active Application Discontinuation
- 1997-07-17 JP JP10505626A patent/JP3020281B2/ja not_active Expired - Fee Related
- 1997-07-17 ES ES97933683T patent/ES2147453T3/es not_active Expired - Lifetime
- 1997-07-17 ZA ZA976331A patent/ZA976331B/xx unknown
- 1997-07-17 DK DK97933683T patent/DK0880524T3/da active
- 1997-07-17 HU HU9902311A patent/HUP9902311A3/hu unknown
- 1997-07-17 CZ CZ982654A patent/CZ265498A3/cs unknown
- 1997-07-17 EP EP99119410A patent/EP0978517A3/de not_active Withdrawn
- 1997-07-17 AT AT97933683T patent/ATE191913T1/de active
- 1997-07-17 CN CN97194506A patent/CN1219936A/zh active Pending
- 1997-07-17 IL IL12645397A patent/IL126453A0/xx unknown
- 1997-07-17 PL PL97328824A patent/PL328824A1/xx unknown
- 1997-07-17 BR BR9710747A patent/BR9710747A/pt unknown
- 1997-07-17 SK SK1144-98A patent/SK114498A3/sk unknown
- 1997-07-17 AU AU36955/97A patent/AU3695597A/en not_active Abandoned
- 1997-07-18 HR HR19629378.2A patent/HRP970395A2/hr not_active Application Discontinuation
- 1997-07-18 ID IDP972495A patent/ID19106A/id unknown
-
1998
- 1998-08-20 BG BG102707A patent/BG102707A/xx active Pending
- 1998-08-21 NO NO983860A patent/NO983860L/no not_active Application Discontinuation
-
2000
- 2000-06-30 GR GR20000401543T patent/GR3033842T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EE9800451A (et) | 1999-06-15 |
| NO983860D0 (no) | 1998-08-21 |
| JP2000501420A (ja) | 2000-02-08 |
| PL328824A1 (en) | 1999-02-15 |
| CA2256736A1 (en) | 1998-01-29 |
| CZ265498A3 (cs) | 1998-12-16 |
| IL126453A0 (en) | 1999-08-17 |
| BG102707A (en) | 1999-09-30 |
| JP3020281B2 (ja) | 2000-03-15 |
| EP0880524A1 (de) | 1998-12-02 |
| HRP970395A2 (en) | 1998-08-31 |
| EP0978517A2 (de) | 2000-02-09 |
| DE19629378A1 (de) | 1998-01-29 |
| PT880524E (pt) | 2000-07-31 |
| BR9710747A (pt) | 1999-08-17 |
| EP0880524B1 (de) | 2000-04-19 |
| ZA976331B (en) | 1999-01-25 |
| HUP9902311A3 (en) | 2000-06-28 |
| ATE191913T1 (de) | 2000-05-15 |
| HUP9902311A2 (hu) | 1999-10-28 |
| EP0978517A3 (de) | 2003-11-12 |
| GR3033842T3 (en) | 2000-10-31 |
| DK0880524T3 (da) | 2000-07-17 |
| CN1219936A (zh) | 1999-06-16 |
| SK114498A3 (en) | 1999-02-11 |
| ES2147453T3 (es) | 2000-09-01 |
| DE59701467D1 (de) | 2000-05-25 |
| ID19106A (id) | 1998-06-18 |
| TR199801659T2 (xx) | 1998-12-21 |
| WO1998003511A1 (de) | 1998-01-29 |
| AU3695597A (en) | 1998-02-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |