BG102707A - New triazolopurinpurines, method for their preparation and appplication as medicamentous forms - Google Patents

New triazolopurinpurines, method for their preparation and appplication as medicamentous forms

Info

Publication number
BG102707A
BG102707A BG102707A BG10270798A BG102707A BG 102707 A BG102707 A BG 102707A BG 102707 A BG102707 A BG 102707A BG 10270798 A BG10270798 A BG 10270798A BG 102707 A BG102707 A BG 102707A
Authority
BG
Bulgaria
Prior art keywords
new
preparation
triazolopurinpurines
appplication
receptors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
BG102707A
Other languages
Bulgarian (bg)
English (en)
Inventor
Ulrike Kuefner-Muehl
Werner Kummer
Gerald Pohl
Wolfram Gaida
Erich Lehr
Joachim Mierau
Thomas Weiser
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH Co KG
Original Assignee
Boehringer Ingelheim Pharma GmbH Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CA002242097A external-priority patent/CA2242097C/en
Application filed by Boehringer Ingelheim Pharma GmbH Co KG filed Critical Boehringer Ingelheim Pharma GmbH Co KG
Publication of BG102707A publication Critical patent/BG102707A/xx
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/36—Antigestagens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Endocrinology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BG102707A 1996-07-20 1998-08-20 New triazolopurinpurines, method for their preparation and appplication as medicamentous forms Pending BG102707A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19629378A DE19629378A1 (de) 1996-07-20 1996-07-20 Neue Triazolopurine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
PCT/EP1997/003841 WO1998003511A1 (de) 1996-07-20 1997-07-17 Neue triazolopurine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
CA002242097A CA2242097C (en) 1996-07-20 1998-06-26 Imidazotriazolopyrimidines, process for preparing them and their use as pharmaceutical compositions

Publications (1)

Publication Number Publication Date
BG102707A true BG102707A (en) 1999-09-30

Family

ID=32963000

Family Applications (1)

Application Number Title Priority Date Filing Date
BG102707A Pending BG102707A (en) 1996-07-20 1998-08-20 New triazolopurinpurines, method for their preparation and appplication as medicamentous forms

Country Status (25)

Country Link
EP (2) EP0880524B1 (xx)
JP (1) JP3020281B2 (xx)
CN (1) CN1219936A (xx)
AT (1) ATE191913T1 (xx)
AU (1) AU3695597A (xx)
BG (1) BG102707A (xx)
BR (1) BR9710747A (xx)
CA (1) CA2256736A1 (xx)
CZ (1) CZ265498A3 (xx)
DE (2) DE19629378A1 (xx)
DK (1) DK0880524T3 (xx)
EE (1) EE9800451A (xx)
ES (1) ES2147453T3 (xx)
GR (1) GR3033842T3 (xx)
HR (1) HRP970395A2 (xx)
HU (1) HUP9902311A3 (xx)
ID (1) ID19106A (xx)
IL (1) IL126453A0 (xx)
NO (1) NO983860L (xx)
PL (1) PL328824A1 (xx)
PT (1) PT880524E (xx)
SK (1) SK114498A3 (xx)
TR (1) TR199801659T2 (xx)
WO (1) WO1998003511A1 (xx)
ZA (1) ZA976331B (xx)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19826843A1 (de) * 1998-06-16 1999-12-23 Boehringer Ingelheim Pharma Neue Imidazotriazolopyrimidine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
US6492377B1 (en) 1998-06-25 2002-12-10 Boehringer Ingelheim Pharma Kg Imidazotriazolopyrimidines with adenosine-antagonistic activity
WO2000012511A1 (de) * 1998-08-27 2000-03-09 Boehringer Ingelheim Pharma Kg Imidazotriazolopyrimidine
WO2004075846A2 (en) 2003-02-25 2004-09-10 Bristol-Myers Squibb Company Pyrazolopurine-based tricyclic compounds and pharmaceutical compositions comprising same
US7071333B2 (en) 2003-07-30 2006-07-04 Bristol-Myers Squibb Company Triazolopurine-based tricyclic compounds and pharmaceutical compositions comprising same
EP2044074A2 (en) * 2006-06-23 2009-04-08 Incyte Corporation Purinone derivatives as hm74a agonists
IL303087B1 (en) 2018-02-27 2024-08-01 Incyte Corp Midazopyrimidines and triazolopyrimidines as A2A /A2B inhibitors
US11168089B2 (en) 2018-05-18 2021-11-09 Incyte Corporation Fused pyrimidine derivatives as A2A / A2B inhibitors
CN113166153A (zh) 2018-07-05 2021-07-23 因赛特公司 作为a2a/a2b抑制剂的稠合吡嗪衍生物
JP7241871B2 (ja) 2018-11-30 2023-03-17 メルク・シャープ・アンド・ドーム・エルエルシー アデノシン受容体拮抗薬としての９－置換されたアミノトリアゾロキナゾリン誘導体、医薬組成物及びそれらの使用
TWI829857B (zh) 2019-01-29 2024-01-21 美商英塞特公司 作為a2a / a2b抑制劑之吡唑并吡啶及三唑并吡啶
CN112778311B (zh) * 2019-11-01 2024-06-04 上海翰森生物医药科技有限公司 含氮并环类衍生物抑制剂、其制备方法和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA902282B (en) * 1989-03-29 1990-12-28 Merrell Dow Pharma Selective adenosine receptor compounds
IT1264901B1 (it) * 1993-06-29 1996-10-17 Schering Plough S P A Analoghi eterociclici di 1,2,4-triazolo(15-c)pirimidine ad attivita' antagonista per il recettore a2 dell'adenosina
JPH083169A (ja) * 1994-06-15 1996-01-09 Yamasa Shoyu Co Ltd ４−メチル−１Ｈ−［１，２，４］トリアゾロ［１，５−ａ］プリン−９（４Ｈ）−オン類

Also Published As

Publication number Publication date
DE59701467D1 (de) 2000-05-25
NO983860D0 (no) 1998-08-21
ES2147453T3 (es) 2000-09-01
ID19106A (id) 1998-06-18
PT880524E (pt) 2000-07-31
NO983860L (no) 1998-10-21
JP2000501420A (ja) 2000-02-08
EP0978517A3 (de) 2003-11-12
PL328824A1 (en) 1999-02-15
ATE191913T1 (de) 2000-05-15
HUP9902311A2 (hu) 1999-10-28
BR9710747A (pt) 1999-08-17
AU3695597A (en) 1998-02-10
EP0880524A1 (de) 1998-12-02
CZ265498A3 (cs) 1998-12-16
JP3020281B2 (ja) 2000-03-15
CA2256736A1 (en) 1998-01-29
TR199801659T2 (xx) 1998-12-21
IL126453A0 (en) 1999-08-17
HUP9902311A3 (en) 2000-06-28
GR3033842T3 (en) 2000-10-31
WO1998003511A1 (de) 1998-01-29
DK0880524T3 (da) 2000-07-17
EE9800451A (et) 1999-06-15
HRP970395A2 (en) 1998-08-31
ZA976331B (en) 1999-01-25
EP0978517A2 (de) 2000-02-09
EP0880524B1 (de) 2000-04-19
CN1219936A (zh) 1999-06-16
DE19629378A1 (de) 1998-01-29
SK114498A3 (en) 1999-02-11

Similar Documents

Publication Publication Date Title
BG103740A (en) Phytostyrene composition for the prevention of the alzheimer's disease
MD1745B2 (en) 4,5-dimethyl-N-2-propenyl-2-(trimethylsilyl)-3-thiophencarboxamide, fungicidal composition on base thereof and method of plants diseases control
AU4347796A (en) Use of nebivolol as an anti-atherogenic
MX9704030A (es) 1,1-dioxidos de 2-heterocicliloxi y tiometil-1,2,5-tiadiazolidin-3-ona y composiciones y metodo de uso de los mismos.
BG104315A (en) Prostaglandine agonists and their application for the treatment of osteal diseases
BG102616A (en) Substituted aza- and diazacycloheptane and cyclooctane derivatives and their application
CA2272584A1 (en) Novel substituted pyrazole derivatives for the treatment of cardiocirculatory diseases
BG101131A (en) 2-oxo-and 2-thio-1,2-dihydroquinolinyl-oxazolidinons
BG101901A (en) 2-methyl-thieno-benzodiazepine formulation for oral application
UA39158C2 (uk) Похідні n4-оксикарбоніл-5'-дезокси-5-фторцитидину та фармацевтичний препарат на їх основі
MY132529A (en) Paroxetine hydrochloride anhydrate
PL317830A1 (en) Derivatives of a sterol used for controlling meiosis
MX9704037A (es) 1,1-dioxidos de 1,2,5-tiadiazolidin-3-ona 2-substituida y composiciones y metodo de uso de los mismos.
BG103219A (en) Benzamidine derivatives and their application as medicamentous forms with ltb-4-antagonist effect
BG102707A (en) New triazolopurinpurines, method for their preparation and appplication as medicamentous forms
IL116746A0 (en) Use of 3, 4-diphenyl chromans for the preparation of pharmaceutical compositions
BG102623A (en) New derivatives of benzoylguanadine, methods for their preparation and application for the manufacture of medicamentous forms
ATE82127T1 (de) N-acetylglucosamin-zubereitungen zur buccalen anwendung.
BG105275A (en) Tan-1057 derivatives
MX9704034A (es) Derivados y composiciones de 1,1-dioxido de 2-arilcarboniloximetil-1,2,5-tiadiazolidin-3-ona substituido y metodo de uso.
BG104179A (en) Phanquinon administration for the treatment of the alzheimer's disease
BG102667A (en) Diosgenine-containing composition
BG103649A (en) Method for the preparation of eprosartan
IL116745A0 (en) Use of 3,4-diphenyl chromans for the preparation of pharmaceutical compositions
BG103650A (en) Method for the preparation of eprosartan