NO982154D0 - Faktor VIII-hybrid med modifisert aktivitet - Google Patents

Faktor VIII-hybrid med modifisert aktivitet

Info

Publication number
NO982154D0
NO982154D0 NO982154A NO982154A NO982154D0 NO 982154 D0 NO982154 D0 NO 982154D0 NO 982154 A NO982154 A NO 982154A NO 982154 A NO982154 A NO 982154A NO 982154 D0 NO982154 D0 NO 982154D0
Authority
NO
Norway
Prior art keywords
factor viii
modified activity
hybrid
viii hybrid
activity
Prior art date
Application number
NO982154A
Other languages
English (en)
Other versions
NO982154L (no
Inventor
Johannes J Voorberg
Original Assignee
Immuno Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immuno Ag filed Critical Immuno Ag
Publication of NO982154D0 publication Critical patent/NO982154D0/no
Publication of NO982154L publication Critical patent/NO982154L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8121—Serpins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/815—Protease inhibitors from leeches, e.g. hirudin, eglin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/10—Factor VIII, AHF; related peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
NO982154A 1995-11-13 1998-05-12 Faktor VIII-hybrid med modifisert aktivitet NO982154L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/558,107 US5910481A (en) 1995-11-13 1995-11-13 Hybrid proteins with modified activity
PCT/EP1996/004977 WO1997018315A1 (en) 1995-11-13 1996-11-13 Hybrid factor viii with modified activity

Publications (2)

Publication Number Publication Date
NO982154D0 true NO982154D0 (no) 1998-05-12
NO982154L NO982154L (no) 1998-07-13

Family

ID=24228239

Family Applications (1)

Application Number Title Priority Date Filing Date
NO982154A NO982154L (no) 1995-11-13 1998-05-12 Faktor VIII-hybrid med modifisert aktivitet

Country Status (10)

Country Link
US (5) US5910481A (no)
EP (1) EP0861326A1 (no)
JP (1) JP2001501803A (no)
AU (1) AU707410B2 (no)
CA (1) CA2235628A1 (no)
CZ (1) CZ140298A3 (no)
HU (1) HUP9901161A3 (no)
NO (1) NO982154L (no)
PL (1) PL326673A1 (no)
WO (1) WO1997018315A1 (no)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5910481A (en) * 1995-11-13 1999-06-08 Immuno Ag Hybrid proteins with modified activity
US7560107B2 (en) * 1996-06-26 2009-07-14 Emory University Modified factor VIII
US20020019036A1 (en) * 1996-12-13 2002-02-14 Hans-Peter Schwarz Von willebrand factor derivatives and methods of isolating proteins that bind to von willebrand factor
EP1074842A1 (en) * 1999-07-21 2001-02-07 Institut National De La Sante Et De La Recherche Medicale (Inserm) Catalytic anti-factor VIII allo-antibodies
ES2331909T3 (es) * 2001-06-14 2010-01-20 The Scripps Research Institute Factor viii estabilizado con enlaces disulfuro modificados geneticamente.
DE602005023429D1 (de) 2004-10-19 2010-10-21 Lonza Ag Verfahren zur festphasen-peptidsynthese
EP2103630B1 (en) * 2006-12-15 2011-11-16 Institute Of Radiation Medicine Academy Of Military Medical Sciences, PLA Preparation of low bleeding anticoagulant fusion protein and its use
JP5624891B2 (ja) * 2007-12-31 2014-11-12 バクスター・インターナショナル・インコーポレイテッドＢａｘｔｅｒ Ｉｎｔｅｒｎａｔｉｏｎａｌ Ｉｎｃｏｒｐ０Ｒａｔｅｄ ヒト血液凝固因子を発現するトランスジェニック非ヒト動物
WO2011017414A2 (en) 2009-08-04 2011-02-10 Baxter International Inc. Transgenic mouse lacking endogenous fviii and vwf - a model of hemophilia a
JP6174367B2 (ja) * 2013-04-26 2017-08-02 株式会社Ｌｓｉメディエンス トロンビン含有試薬及び測定方法

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0162067B1 (en) * 1983-10-28 1992-07-15 Genetics Institute, Inc. Production of factor viii and related products
EP0146903A3 (en) * 1983-12-19 1987-07-22 Schering Corporation Production of a vector encoding a novel hybrid interferon species
DE3588242T2 (de) * 1984-01-12 2004-03-11 Chiron Corp. (N.D.Ges.D. Staates Delaware), Emeryville Für Faktor-VIIIc kodierende DNA-Sequenzen und verwandte DNA-Konstruktionen
FI86885C (fi) * 1984-04-20 1992-10-26 Genentech Inc Foerfarande foer framstaellning av human rekombinantfaktor viii och nukleinsyrasekvenser och vektorer anvaend daertill
US4868112A (en) * 1985-04-12 1989-09-19 Genetics Institute, Inc. Novel procoagulant proteins
IL83192A (en) * 1986-07-18 1992-11-15 Gist Brocades Nv Method for the preparation of proteins with factor viii activity by microbial host cells;expression vectors,host cells,antibodies
JPH01502080A (ja) * 1986-11-17 1989-07-27 ニュー・イングランド・メディカル・センター 組み換えビタミンｋ依存性蛋白質のガンマカルボキシル化の増強
NL8701021A (nl) * 1987-04-29 1988-11-16 Stichting Centraal Lab Humane t-pa(u-pa) substitutie-mutant eiwitten, daarvoor coderend recombinant dna, getransfecteerde gastheercellen, bereiding van de mutant eiwitten, en farmaceutische preparaten.
PT87688B (pt) * 1987-06-12 1992-09-30 Hoechst Japan Processo para a preparacao de proteina hibrida c
EP0690126B1 (en) * 1987-06-12 2001-11-28 Baxter Aktiengesellschaft Novel proteins with factor VIII activitiy: process for their preparation using genetically-engineered cells and pharmaceutical compositions containing them
PT88641B (pt) * 1987-10-02 1993-04-30 Genentech Inc Metodo para a preparacao de uma variante de adesao
DK176140B1 (da) * 1988-07-20 2006-09-25 Schering Ag Patentabteilung Flagermusspyt-plasminogenaktivatorer
DE69032284T2 (de) * 1989-03-21 1998-10-08 Vical, Inc., San Diego, Calif. Expression von exogenen polynukleotidsequenzen in wirbeltieren
NL8902454A (nl) * 1989-10-03 1991-05-01 Stichting Centraal Lab Mutanten van de humane plasminogeen activator inhibitor 1 (pai-1), hun bereiding en toepassing, en recombinante polynucleotiden die voor deze mutanten coderende genetische informatie omvatten.
US5358932A (en) * 1989-12-29 1994-10-25 Zymogenetics, Inc. Hybrid protein C
ATE135044T1 (de) * 1990-01-25 1996-03-15 Univ Washington Faktor x-laci-hybridprotein
IL96519A0 (en) * 1990-02-15 1991-08-16 Harvard College Covalent angiogenin/rnase hybrids
US5298422A (en) * 1991-11-06 1994-03-29 Baylor College Of Medicine Myogenic vector systems
US5364771A (en) * 1992-04-07 1994-11-15 Emory University Hybrid human/porcine factor VIII
AU5602394A (en) * 1992-11-13 1994-06-08 Duke University Chimeric blood coagulation proteins
US5563045A (en) * 1992-11-13 1996-10-08 Genetics Institute, Inc. Chimeric procoagulant proteins
WO1995018829A1 (en) * 1994-01-07 1995-07-13 Novo Nordisk A/S Factor viii derivatives
AU1382595A (en) * 1994-01-07 1995-08-01 Novo Nordisk A/S Factor viii derivatives
AU1382695A (en) * 1994-01-07 1995-08-01 Novo Nordisk A/S Factor viii derivatives
US5910481A (en) * 1995-11-13 1999-06-08 Immuno Ag Hybrid proteins with modified activity

Also Published As

Publication number Publication date
PL326673A1 (en) 1998-10-12
AU707410B2 (en) 1999-07-08
NO982154L (no) 1998-07-13
WO1997018315A1 (en) 1997-05-22
US6051418A (en) 2000-04-18
HUP9901161A2 (hu) 1999-07-28
JP2001501803A (ja) 2001-02-13
CZ140298A3 (cs) 1998-08-12
US5910481A (en) 1999-06-08
AU7624296A (en) 1997-06-05
EP0861326A1 (en) 1998-09-02
US6130203A (en) 2000-10-10
HUP9901161A3 (en) 2001-10-29
CA2235628A1 (en) 1997-05-22
US6156888A (en) 2000-12-05
US5869292A (en) 1999-02-09

Similar Documents

Publication Publication Date Title
DE69606993D1 (de) Nachladbarer auto-injektor
BR9606059A (pt) Automóvel
DE69600615D1 (de) Fahrzeuggenerator
DE69601275D1 (de) Stromabnehmerelemente
NO982154L (no) Faktor VIII-hybrid med modifisert aktivitet
KR970047092U (ko) 자동차용 배터리
KR970035004U (ko) 차량용 배터리 홀더
KR960004936U (ko) 수육양용 프라잉카
KR970035008U (ko) 자동차 배터리 고정 구조
BR9500927A (pt) Veiculo hibrido aero-termodinâmico
KR970025909U (ko) 자동차용 배터리
KR970047085U (ko) 차량용 배터리
KR970033870U (ko) 자동차의 수납장치
KR970041044U (ko) 자동차의 충전 제어장치
SE9501499D0 (sv) Linvagn
KR970047068U (ko) 자동차용 축전지 케이스
KR970019793U (ko) 자동차용 배터리 케이스
KR970009043U (ko) 자동차용 티슈 홀다
LV11395A (lv) Akumulatoru baterijas kontrolierice
KR970035001U (ko) 자동차용 밧데리 트레이
KR970012481U (ko) 자동차의 후크 취부구조
KR970031812U (ko) 지지부가 구비된 자동차 헤드 레스트
KR970007241U (ko) 차량용 베터리구조
KR970047059U (ko) 차량용 밧데리구조
KR970035024U (ko) 차량용 배터리 베이스