NO975752L - Varmesjokkproteiner fra streptokokker i HSP70 familien - Google Patents

Varmesjokkproteiner fra streptokokker i HSP70 familien

Info

Publication number
NO975752L
NO975752L NO975752A NO975752A NO975752L NO 975752 L NO975752 L NO 975752L NO 975752 A NO975752 A NO 975752A NO 975752 A NO975752 A NO 975752A NO 975752 L NO975752 L NO 975752L
Authority
NO
Norway
Prior art keywords
seq
heat shock
shock proteins
nucleotide
amino acid
Prior art date
Application number
NO975752A
Other languages
English (en)
Other versions
NO975752D0 (no
Inventor
Josee Hamel
Bernard R Brodeur
Denis Martin
Clement Rioux
Original Assignee
Biochem Vaccines Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/472,534 external-priority patent/US5919620A/en
Application filed by Biochem Vaccines Inc filed Critical Biochem Vaccines Inc
Publication of NO975752D0 publication Critical patent/NO975752D0/no
Publication of NO975752L publication Critical patent/NO975752L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
    • C07K16/1275—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Streptococcus (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C07K14/3156—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Plant Pathology (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Distillation Of Fermentation Liquor, Processing Of Alcohols, Vinegar And Beer (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Det er beskrevet varmesjokkproteiner (HSPs) fra Streptococcus pneumoniae, Streptococcus pyo- genes eller Streptococcus agalactiae med en tilsyne- latende molekylmasse på 70-72 kDa, immunologisk beslektede polypeptider, nukleotid og avledete aminosyresekvenser av HSP72 fra S. pneumoniae (SEQ ID nr. 4, SEQ ID nr.5), nukleotid og avledete aminosyresekvenser fra HSP70 fra S. pyogenes (SEQ ID nr. 19 og SEQ ID nr. 20), nukleotid og avledet aminosyre sekvenser fra HSP70 fra S. agalactiae (SEQ ID nr. 21 og SEQ ID nr. 22), antistoffer som binder seg til nevnte varmesjokk proteiner og rekombinante DNA metoder for fremstilling av nevnte Varmesjokk- proteiner og immunologisk beslektede polypeptider. Polypeptidene, DNA sekvensene og antistoffene i følge foreliggende oppfinnelse tilveiebringer nye anordninger for diagnose, for å hindre og/eller behandle streptococcale sykdommer.
NO975752A 1995-06-07 1997-12-05 Varmesjokkproteiner fra streptokokker i HSP70 familien NO975752L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/472,534 US5919620A (en) 1995-06-07 1995-06-07 Heat shock protein HSP72 of Streptococcus pneumoniae
US180595P 1995-08-04 1995-08-04
PCT/CA1996/000322 WO1996040928A1 (en) 1995-06-07 1996-05-17 Streptococcal heat shock proteins members of the hsp70 family

Publications (2)

Publication Number Publication Date
NO975752D0 NO975752D0 (no) 1997-12-05
NO975752L true NO975752L (no) 1998-02-06

Family

ID=26669494

Family Applications (1)

Application Number Title Priority Date Filing Date
NO975752A NO975752L (no) 1995-06-07 1997-12-05 Varmesjokkproteiner fra streptokokker i HSP70 familien

Country Status (18)

Country Link
EP (1) EP0832238A1 (no)
JP (1) JPH11507214A (no)
KR (1) KR19990022742A (no)
CN (1) CN1192241A (no)
AP (1) AP9701163A0 (no)
AR (1) AR003124A1 (no)
AU (1) AU700080B2 (no)
BR (1) BR9609399A (no)
CA (1) CA2224015A1 (no)
CZ (1) CZ394297A3 (no)
EA (1) EA199800046A1 (no)
HU (1) HUP0600442A3 (no)
IL (1) IL118329A0 (no)
NO (1) NO975752L (no)
PL (1) PL323781A1 (no)
SK (1) SK168497A3 (no)
TR (1) TR199701537T1 (no)
WO (1) WO1996040928A1 (no)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6245335B1 (en) 1996-05-01 2001-06-12 The Rockefeller University Choline binding proteins for anti-pneumococcal vaccines
WO1997041151A2 (en) * 1996-05-01 1997-11-06 The Rockefeller University Choline binding proteins for anti-pneumococcal vaccines
CA2315880A1 (en) * 1997-12-31 1999-07-15 Stressgen Biotechnologies Corporation Streptococcal heat shock proteins of the hsp60 family
US6497880B1 (en) 1998-12-08 2002-12-24 Stressgen Biotechnologies Corporation Heat shock genes and proteins from Neisseria meningitidis, Candida glabrata and Aspergillus fumigatus
US7128918B1 (en) 1998-12-23 2006-10-31 Id Biomedical Corporation Streptococcus antigens
CN100398653C (zh) * 1998-12-23 2008-07-02 益得生物医学公司 新颖的链球菌抗原
WO2000056359A2 (en) 1999-03-19 2000-09-28 Smithkline Beecham Biologicals S.A. Vaccine against streptococcus pneumoniae
US7015309B1 (en) 1999-06-23 2006-03-21 The Wistar Institute Of Anatomy And Biology Pyrrhocoricin-derived peptides, and methods of use thereof
GB9918319D0 (en) 1999-08-03 1999-10-06 Smithkline Beecham Biolog Vaccine composition
AU2005204321B2 (en) * 1999-08-19 2008-07-10 Immunobiology Limited Vaccines from Infectious Agents
GB9919734D0 (en) * 1999-08-19 1999-10-20 Colaco Camilo Vaccines from infectious agents
CA2398808A1 (en) * 2000-01-21 2001-07-26 The Wistar Institute Of Anatomy & Biology Biocidal molecules, macromolecular targets and methods of production and use
US6866855B2 (en) 2000-06-12 2005-03-15 University Of Saskatchewan Immunization of dairy cattle with GapC protein against Streptococcus infection
DK1294771T3 (da) 2000-06-12 2008-12-15 Univ Saskatchewan Kimært GapC-protein fra Streptococcus og anvendelse deraf til vaccinering og diagnosticering
US6833134B2 (en) 2000-06-12 2004-12-21 University Of Saskacthewan Immunization of dairy cattle with GapC protein against Streptococcus infection
GB0021757D0 (en) * 2000-09-04 2000-10-18 Colaco Camilo Vaccine against microbial pathogens
GB0022742D0 (en) 2000-09-15 2000-11-01 Smithkline Beecham Biolog Vaccine
WO2004014417A2 (en) 2002-08-02 2004-02-19 Glaxosmithkline Biologicals Sa Vaccine compositions comprising l2 and/or l3 immunotype lipooligosaccharides from lgtb- neisseria minigitidis
US8409587B2 (en) 2002-11-01 2013-04-02 Glaxosmithkline Biologicals S.A. Immunogenic composition
EP1601770B1 (en) * 2003-03-04 2009-09-02 Intercell AG Streptococcus pyogenes antigens
EP1615950A2 (en) * 2003-04-15 2006-01-18 Intercell AG S. pneumoniae antigens
ES2346314T3 (es) 2003-10-02 2010-10-14 Glaxosmithkline Biolog Sa Antigenos de b. pertussis y uso de los mismos en vacunacion.
GB0505996D0 (en) 2005-03-23 2005-04-27 Glaxosmithkline Biolog Sa Fermentation process
TWI457133B (zh) 2005-12-13 2014-10-21 Glaxosmithkline Biolog Sa 新穎組合物
CA2636566C (en) 2006-01-17 2018-03-13 Arne Forsgren A novel surface exposed haemophilus influenzae protein (protein e; pe)
WO2011110634A1 (en) 2010-03-10 2011-09-15 Glaxosmithkline Biologicals S.A. Vaccine composition
GB201015132D0 (en) 2010-09-10 2010-10-27 Univ Bristol Vaccine composition
CN103146734B (zh) * 2013-03-12 2014-10-01 中国人民解放军军事医学科学院军事兽医研究所 抗烧烫伤感染多器官衰竭绿脓杆菌毒素疫苗
CN104001164A (zh) * 2014-04-23 2014-08-27 杭州师范大学 一种嗜水气单胞菌热激蛋白亚单位疫苗及其制备方法
CN114805567B (zh) * 2022-06-27 2022-09-16 和元生物技术（上海）股份有限公司 识别外泌体的标志蛋白hspa1a的单克隆抗体、方法和应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0571538T5 (da) * 1991-02-15 2002-03-04 Uab Research Foundation Strukturgen for pneumokokprotein
IT1262896B (it) * 1992-03-06 1996-07-22 Composti coniugati formati da proteine heat shock (hsp) e oligo-poli- saccaridi, loro uso per la produzione di vaccini.

Also Published As

Publication number Publication date
IL118329A0 (en) 1996-09-12
AU700080B2 (en) 1998-12-17
BR9609399A (pt) 2001-08-28
AR003124A1 (es) 1998-07-08
EP0832238A1 (en) 1998-04-01
SK168497A3 (en) 1998-07-08
CZ394297A3 (cs) 1998-04-15
CA2224015A1 (en) 1996-12-19
HUP0600442A2 (en) 2006-08-28
PL323781A1 (en) 1998-04-27
HUP0600442A3 (en) 2007-03-28
KR19990022742A (ko) 1999-03-25
TR199701537T1 (xx) 1998-03-21
AP9701163A0 (en) 1998-01-31
NO975752D0 (no) 1997-12-05
CN1192241A (zh) 1998-09-02
WO1996040928A1 (en) 1996-12-19
JPH11507214A (ja) 1999-06-29
EA199800046A1 (ru) 1998-06-25
AU5682896A (en) 1996-12-30

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