ATE474595T1 - B. pertussis antigene und ihre verwendung bei der vakzinierung - Google Patents
B. pertussis antigene und ihre verwendung bei der vakzinierungInfo
- Publication number
- ATE474595T1 ATE474595T1 AT04765806T AT04765806T ATE474595T1 AT E474595 T1 ATE474595 T1 AT E474595T1 AT 04765806 T AT04765806 T AT 04765806T AT 04765806 T AT04765806 T AT 04765806T AT E474595 T1 ATE474595 T1 AT E474595T1
- Authority
- AT
- Austria
- Prior art keywords
- polypeptides
- basb232
- antigen
- vaccination
- categories
- Prior art date
Links
- 239000000427 antigen Substances 0.000 title abstract 4
- 108091007433 antigens Proteins 0.000 title abstract 4
- 102000036639 antigens Human genes 0.000 title abstract 4
- 241000588832 Bordetella pertussis Species 0.000 title 1
- 238000002255 vaccination Methods 0.000 title 1
- 229920001184 polypeptide Polymers 0.000 abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 3
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 abstract 2
- 241000588807 Bordetella Species 0.000 abstract 1
- 108090001030 Lipoproteins Proteins 0.000 abstract 1
- 102000004895 Lipoproteins Human genes 0.000 abstract 1
- 108010073429 Type V Secretion Systems Proteins 0.000 abstract 1
- 230000002163 immunogen Effects 0.000 abstract 1
- 229910052742 iron Inorganic materials 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 102000040430 polynucleotide Human genes 0.000 abstract 1
- 108091033319 polynucleotide Proteins 0.000 abstract 1
- 239000002157 polynucleotide Substances 0.000 abstract 1
- 230000000069 prophylactic effect Effects 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 238000010188 recombinant method Methods 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 239000003053 toxin Substances 0.000 abstract 1
- 231100000765 toxin Toxicity 0.000 abstract 1
- 108700012359 toxins Proteins 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/099—Bordetella
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0323113A GB0323113D0 (en) | 2003-10-02 | 2003-10-02 | Immunogenic composition |
| GB0323112A GB0323112D0 (en) | 2003-10-02 | 2003-10-02 | Novel compounds |
| PCT/EP2004/011082 WO2005032584A2 (en) | 2003-10-02 | 2004-10-01 | Pertussis antigens and use thereof in vaccination |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE474595T1 true ATE474595T1 (de) | 2010-08-15 |
Family
ID=34424892
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04765806T ATE474595T1 (de) | 2003-10-02 | 2004-10-01 | B. pertussis antigene und ihre verwendung bei der vakzinierung |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US8574596B2 (de) |
| EP (1) | EP1667712B1 (de) |
| AT (1) | ATE474595T1 (de) |
| AU (1) | AU2004277342B2 (de) |
| CA (1) | CA2539715C (de) |
| DE (1) | DE602004028262D1 (de) |
| ES (1) | ES2346314T3 (de) |
| WO (1) | WO2005032584A2 (de) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002020059A2 (en) * | 2000-09-01 | 2002-03-14 | The Government Of The United States Of America As Represented By The Secretary, Department Of Health And Human Services | Vibrio cholerae o139 conjugate vaccines |
| GB0505518D0 (en) * | 2005-03-17 | 2005-04-27 | Chiron Srl | Combination vaccines with whole cell pertussis antigen |
| US9486515B2 (en) | 2005-06-27 | 2016-11-08 | Glaxosmithkline Biologicals S.A. | Immunogenic composition |
| WO2009094006A2 (en) | 2007-10-25 | 2009-07-30 | Wake Forest University Health Sciences | Bordetella outer-membrane protein antigens and methods of making and using the same |
| CU23679A1 (es) * | 2007-10-30 | 2011-07-11 | Ct Ingenieria Genetica Biotech | Variantes de pertactinas para uso vacunal |
| EP2430040A1 (de) * | 2009-05-11 | 2012-03-21 | Novartis AG | Antigenaufreinigungsverfahren für pertactinantigen |
| WO2010135704A2 (en) * | 2009-05-22 | 2010-11-25 | Institute For Systems Biology | Secretion-related bacterial proteins for nlrc4 stimulation |
| WO2012041899A1 (en) * | 2010-09-28 | 2012-04-05 | Xbrane Bioscience Ab | Fusion protein for secretory protein expression |
| WO2012104821A1 (en) * | 2011-02-04 | 2012-08-09 | Pfizer Inc. | Immunogenic bordetella bronchiseptica compositions |
| WO2014024026A1 (en) | 2012-08-06 | 2014-02-13 | Glaxosmithkline Biologicals S.A. | Method for eliciting in infants an immune response against rsv and b. pertussis |
| US20140037680A1 (en) | 2012-08-06 | 2014-02-06 | Glaxosmithkline Biologicals, S.A. | Novel method |
| JP6198298B2 (ja) * | 2013-04-02 | 2017-09-20 | 国立感染症研究所長 | 百日咳の血清診断方法 |
| KR20160040290A (ko) * | 2013-08-05 | 2016-04-12 | 글락소스미스클라인 바이오로지칼즈 에스.에이. | 조합 면역원성 조성물 |
| EP2921178A1 (de) * | 2014-03-19 | 2015-09-23 | The Provost, Fellows, Foundation Scholars, & the other members of Board, of the College of the Holy & Undiv. Trinity of Queen Elizabeth near Dublin | Toll-like-Rezeptor-2-Agonisten und Impfstoffe und Verwendungen davon |
| WO2016011155A1 (en) * | 2014-07-15 | 2016-01-21 | Kapre Subhash V | Genetically detoxified pertussis that maintains intrinsic adjuvant activity |
| EP3283102A4 (de) * | 2015-04-16 | 2018-10-03 | Inventprise, LLC. | Immunogene impfstoffzusammensetzungen gegen bordetella pertussis |
| US10799573B2 (en) * | 2016-03-30 | 2020-10-13 | Regents Of The University Of Minnesota | Pertussis vaccines and methods of making and using |
| KR101816081B1 (ko) * | 2016-06-03 | 2018-01-08 | 연세대학교 산학협력단 | 백일해균 유래 LysRS를 포함하는 항원 단백질 및 이를 이용한 백일해 진단 방법 |
| KR102426041B1 (ko) * | 2017-08-01 | 2022-07-29 | 주식회사 녹십자 | 냉동 및 해동 과정을 포함하는 백일해균 유래 단백질 수득 방법 |
| US11851479B2 (en) | 2018-06-18 | 2023-12-26 | Dxdiscovery, Inc. | Methods and compositions for pertussis diagnosis |
| CN112912097A (zh) * | 2018-08-23 | 2021-06-04 | 葛兰素史密丝克莱恩生物有限公司 | 免疫原性蛋白和组合物 |
| US11701417B2 (en) | 2019-03-27 | 2023-07-18 | West Virginia University | Vaccine formulation to protect against pertussis |
| US20250263447A1 (en) * | 2020-09-04 | 2025-08-21 | Intravacc B.V. | Ompa mutations enhance omv production in bordetella pertussis |
| CN113354742A (zh) * | 2021-05-10 | 2021-09-07 | 重庆市畜牧科学院 | 一种布鲁氏杆菌基因工程亚单位疫苗及其制备方法和应用 |
| CN118388664B (zh) * | 2024-05-21 | 2024-12-03 | 广东省农业科学院动物卫生研究所 | 副猪嗜血杆菌融合抗原及其应用 |
| CN118853525B (zh) * | 2024-09-26 | 2025-01-07 | 上海羽冠生物技术有限公司 | 经修饰的百日咳鲍特菌菌株 |
| CN120118819B (zh) * | 2025-05-15 | 2025-08-12 | 上海羽冠生物技术有限公司 | 一种经修饰的百日咳鲍特菌菌株及其应用 |
Family Cites Families (53)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB222021A (en) | 1924-01-24 | 1924-09-25 | Berkel & Parnall Mach Mfg Co | Improvements in machines for slicing meat and other substances |
| EP0027888B1 (de) | 1979-09-21 | 1986-04-16 | Hitachi, Ltd. | Halbleiterschalter |
| US4673574A (en) | 1981-08-31 | 1987-06-16 | Anderson Porter W | Immunogenic conjugates |
| US4695624A (en) | 1984-05-10 | 1987-09-22 | Merck & Co., Inc. | Covalently-modified polyanionic bacterial polysaccharides, stable covalent conjugates of such polysaccharides and immunogenic proteins with bigeneric spacers, and methods of preparing such polysaccharides and conjugates and of confirming covalency |
| US4709017A (en) | 1985-06-07 | 1987-11-24 | President And Fellows Of Harvard College | Modified toxic vaccines |
| IT1187753B (it) | 1985-07-05 | 1987-12-23 | Sclavo Spa | Coniugati glicoproteici ad attivita' immunogenica trivalente |
| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| US4950740A (en) | 1987-03-17 | 1990-08-21 | Cetus Corporation | Recombinant diphtheria vaccines |
| US5057540A (en) | 1987-05-29 | 1991-10-15 | Cambridge Biotech Corporation | Saponin adjuvant |
| DE68929323T2 (de) | 1988-12-16 | 2002-04-18 | De Staat Der Nederlanden Vertegenwoordigd Door De Minister Van Welzijn, Volksgezondheid En Cultuur | Pneumolysin-mutanten und pneumokokken-impfstoffe daraus |
| GB8910570D0 (en) * | 1989-05-08 | 1989-06-21 | Wellcome Found | Acellular vaccine |
| FR2646776B1 (fr) | 1989-05-12 | 1994-06-03 | Pasteur Institut | Utilisation de preparations vaccinantes a base d'adenyl cyclase ou de bacteries les produisant en tant qu'antigenes protecteurs contre les effets des bordetella |
| EP0484621A3 (en) * | 1990-07-11 | 1992-08-26 | American Cyanamid Company | Efficacious vaccines against bordetella pertussis comprising a combination of individually purified pertussis antigens |
| CA2087160A1 (en) | 1990-07-16 | 1992-01-17 | P. Frederick Sparling | Antigenic iron repressible proteins from n. meningitidis related to the hemolysin family of toxins |
| ATE253114T1 (de) | 1990-08-23 | 2003-11-15 | Univ North Carolina | Transferrin bindende proteine aus neisseria- gonorrhoeae und neisseria-meningitidis |
| US5912336A (en) | 1990-08-23 | 1999-06-15 | University Of North Carolina At Chapel Hill | Isolated nucleic acid molecules encoding transferrin binding proteins from Neisseria gonorrhoeae and Neisseria meningitidis |
| US5153312A (en) | 1990-09-28 | 1992-10-06 | American Cyanamid Company | Oligosaccharide conjugate vaccines |
| US5476929A (en) | 1991-02-15 | 1995-12-19 | Uab Research Foundation | Structural gene of pneumococcal protein |
| US6592876B1 (en) | 1993-04-20 | 2003-07-15 | Uab Research Foundation | Pneumococcal genes, portions thereof, expression products therefrom, and uses of such genes, portions and products |
| FR2682041B1 (fr) | 1991-10-03 | 1994-01-14 | Pasteur Merieux Serums Vaccins | Vaccin contre les infections a neisseria meningitidis. |
| WO1993015760A1 (en) | 1992-02-11 | 1993-08-19 | U.S. Government, As Represented By The Secretary Of The Army | Dual carrier immunogenic construct |
| ES2130265T3 (es) | 1992-05-06 | 1999-07-01 | Harvard College | Region de union al receptor de la toxina difterica. |
| FR2692592B1 (fr) | 1992-06-19 | 1995-03-31 | Pasteur Merieux Serums Vacc | Fragments d'ADN codant pour les sous-unités du récepteur de la transferrine de Neisseria meningitidis et procédés les exprimant. |
| NZ253137A (en) | 1992-06-25 | 1996-08-27 | Smithkline Beecham Biolog | Vaccine comprising antigen and/or antigenic composition, qs21 (quillaja saponaria molina extract) and 3 de-o-acylated monophosphoryl lipid a. |
| EP0689454B2 (de) | 1993-03-23 | 2005-02-23 | SMITHKLINE BEECHAM BIOLOGICALS s.a. | 3-0-deazylierte monophosphoryl lipid a enthaltende impfstoff-zusammensetzungen |
| EP0693084A4 (de) | 1993-04-06 | 1999-06-02 | Hutchinson Fred Cancer Res | Chimäre cytokinrezeptoren in lymphozyten |
| DK0699076T3 (da) | 1993-05-18 | 2003-03-03 | Univ Ohio State Res Found | Vaccine mod mellemørebetændelse |
| GB9326253D0 (en) | 1993-12-23 | 1994-02-23 | Smithkline Beecham Biolog | Vaccines |
| US5917017A (en) | 1994-06-08 | 1999-06-29 | President And Fellows Of Harvard College | Diphtheria toxin vaccines bearing a mutated R domain |
| US6455673B1 (en) | 1994-06-08 | 2002-09-24 | President And Fellows Of Harvard College | Multi-mutant diphtheria toxin vaccines |
| DE69535905D1 (de) | 1994-07-15 | 2009-02-26 | Coley Pharm Group Inc | Immunomodulatorische Oligonukleotide |
| US5565204A (en) | 1994-08-24 | 1996-10-15 | American Cyanamid Company | Pneumococcal polysaccharide-recombinant pneumolysin conjugate vaccines for immunization against pneumococcal infections |
| IL117483A (en) | 1995-03-17 | 2008-03-20 | Bernard Brodeur | MENINGITIDIS NEISSERIA shell protein is resistant to proteinase K. |
| UA56132C2 (uk) | 1995-04-25 | 2003-05-15 | Смітклайн Бічем Байолоджікалс С.А. | Композиція вакцини (варіанти), спосіб стабілізації qs21 відносно гідролізу (варіанти), спосіб приготування композиції вакцини |
| US5843464A (en) | 1995-06-02 | 1998-12-01 | The Ohio State University | Synthetic chimeric fimbrin peptides |
| JPH11507214A (ja) | 1995-06-07 | 1999-06-29 | バイオケム ヴァシーンズ インク. | Hsp70ファミリーに属する連鎖球菌の熱ショック蛋白質メンバー |
| IL122588A (en) * | 1995-06-23 | 2001-12-23 | Smithkline Beecham Biolog | A combination vaccine containing a polysaccharide conjugated antigen attached to a phosphate aluminum and one or more additional antibodies |
| EP0912608B1 (de) | 1996-05-01 | 2006-04-19 | The Rockefeller University | Cholin-bindendes Protein, welches als gegen Pneumokokken gerichtetes Vakzin verwendet wird |
| FR2751000B1 (fr) | 1996-07-12 | 1998-10-30 | Inst Nat Sante Rech Med | Adn specifiques des bacteries de l'espece neisseria meningitidis, leurs procedes d'obtention et leurs applications biologiques |
| US5882896A (en) | 1996-09-24 | 1999-03-16 | Smithkline Beecham Corporation | M protein |
| US5882871A (en) | 1996-09-24 | 1999-03-16 | Smithkline Beecham Corporation | Saliva binding protein |
| PT942983E (pt) | 1996-10-31 | 2007-02-28 | Human Genome Sciences Inc | Antigénios e vacinas de streptococcus pneumoniae |
| EP0998557A2 (de) | 1997-07-21 | 2000-05-10 | North American Vaccine, Inc. | Modifizierte immunogene pneumolysin, deren zusammensetzungen und deren verwendungen als impfung |
| AU744733B2 (en) | 1997-08-15 | 2002-02-28 | Technology Foundation (Technologiestichting Stw) | Neisseria lactoferrin binding protein |
| GB9717953D0 (en) | 1997-08-22 | 1997-10-29 | Smithkline Beecham Biolog | Vaccine |
| GB9726398D0 (en) | 1997-12-12 | 1998-02-11 | Isis Innovation | Polypeptide and coding sequences |
| US6503511B1 (en) | 1998-04-07 | 2003-01-07 | Medimmune, Inc. | Derivatives of choline binding proteins for vaccines |
| GB9808866D0 (en) | 1998-04-24 | 1998-06-24 | Smithkline Beecham Biolog | Novel compounds |
| US6248329B1 (en) * | 1998-06-01 | 2001-06-19 | Ramaswamy Chandrashekar | Parasitic helminth cuticlin nucleic acid molecules and uses thereof |
| WO2001055309A2 (en) * | 2000-01-31 | 2001-08-02 | Human Genome Sciences, Inc. | Nucleic acids, proteins, and antibodies |
| WO2002077183A2 (en) * | 2001-03-21 | 2002-10-03 | Elitra Pharmaceuticals, Inc. | Identification of essential genes in microorganisms |
| US7285289B2 (en) * | 2002-04-12 | 2007-10-23 | Nagy Jon O | Nanoparticle vaccines |
| US9473463B2 (en) | 2014-07-29 | 2016-10-18 | Combined Conditional Access Development & Support, LLC | Control word and associated entitlement control message caching and reuse |
-
2004
- 2004-10-01 AT AT04765806T patent/ATE474595T1/de not_active IP Right Cessation
- 2004-10-01 AU AU2004277342A patent/AU2004277342B2/en not_active Ceased
- 2004-10-01 US US10/574,297 patent/US8574596B2/en not_active Expired - Fee Related
- 2004-10-01 WO PCT/EP2004/011082 patent/WO2005032584A2/en not_active Ceased
- 2004-10-01 ES ES04765806T patent/ES2346314T3/es not_active Expired - Lifetime
- 2004-10-01 DE DE602004028262T patent/DE602004028262D1/de not_active Expired - Lifetime
- 2004-10-01 CA CA2539715A patent/CA2539715C/en not_active Expired - Fee Related
- 2004-10-01 EP EP04765806A patent/EP1667712B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CA2539715A1 (en) | 2005-04-14 |
| WO2005032584A3 (en) | 2005-11-10 |
| DE602004028262D1 (de) | 2010-09-02 |
| AU2004277342B2 (en) | 2010-12-16 |
| EP1667712A2 (de) | 2006-06-14 |
| US8574596B2 (en) | 2013-11-05 |
| AU2004277342A1 (en) | 2005-04-14 |
| CA2539715C (en) | 2015-02-24 |
| EP1667712B1 (de) | 2010-07-21 |
| WO2005032584A2 (en) | 2005-04-14 |
| US20070116711A1 (en) | 2007-05-24 |
| ES2346314T3 (es) | 2010-10-14 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE474595T1 (de) | B. pertussis antigene und ihre verwendung bei der vakzinierung | |
| IS7601A (is) | Neisser-bóluefnasamsetningar sem innihalda blönduaf mótefnavökvum | |
| CY1118443T1 (el) | Anti-tnf αντισωματα, συνθεσεις, μεθοδοι και χρησεις | |
| WO2002081646A3 (en) | Epitope sequences | |
| ATE524194T1 (de) | Antigene polypeptide | |
| ATE461938T1 (de) | Mit entzündlichen darmerkrankungen (ibd) assoziierte mikrobielle antigene und verfahren derer anwendung | |
| ATE551069T1 (de) | Mucin-fusionspolypeptid-vakzine, zusammensetzungen und ihre verwendung | |
| DK1078063T3 (da) | BASB029-polynukleotider og -polypeptider fra Neisseria meningitidis | |
| NO20005952L (no) | Antigene polypeptider fra Neisseria Meningitidis, tilsvarende polynukleotider og beskyttende antistoffer | |
| DK1163343T3 (da) | Neisseria meningitidis antigene polypeptider, tilsvarende polynukleotider og beskyttende antistoffer | |
| DE69918446D1 (de) | Polynucleotide and polypeptide basb033 aus neisseria meningitidis und ihre verwendungen | |
| ATE354657T1 (de) | Basb019 proteine und gene aus moraxella catarrhalis, antigene, antikörper, und verwendungen | |
| DK1082435T3 (da) | Proteiner og gener fra Moraxella catarrhalis, antigener, antistoffer og anvendelser | |
| WO2000042191A3 (en) | Neisseria meningitidis antigenic polypeptides, corresponding polynucleotides and protective antibodies | |
| DE69827800D1 (de) | Epitope des shigella-artigen toxins und ihre verwendung als impfstoff und in der diagnose | |
| WO2002066503A3 (en) | H. influenzae antigen basb213 | |
| ATE293693T1 (de) | Moraxella catarrhalis antigen basb117 | |
| ATE293692T1 (de) | Moraxella catarrhalis antigen basb120 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |