DE69827800D1 - Epitope des shigella-artigen toxins und ihre verwendung als impfstoff und in der diagnose - Google Patents
Epitope des shigella-artigen toxins und ihre verwendung als impfstoff und in der diagnoseInfo
- Publication number
- DE69827800D1 DE69827800D1 DE69827800T DE69827800T DE69827800D1 DE 69827800 D1 DE69827800 D1 DE 69827800D1 DE 69827800 T DE69827800 T DE 69827800T DE 69827800 T DE69827800 T DE 69827800T DE 69827800 D1 DE69827800 D1 DE 69827800D1
- Authority
- DE
- Germany
- Prior art keywords
- shigella
- diagnosis
- toxin
- epitope
- vaccine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000003745 diagnosis Methods 0.000 title abstract 3
- 239000003053 toxin Substances 0.000 title abstract 3
- 231100000765 toxin Toxicity 0.000 title abstract 3
- 229960005486 vaccine Drugs 0.000 title 1
- 108700012359 toxins Proteins 0.000 abstract 2
- 238000011282 treatment Methods 0.000 abstract 2
- 241001646719 Escherichia coli O157:H7 Species 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 230000002163 immunogen Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
- C07K14/25—Shigella (G)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
- C07K14/245—Escherichia (G)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Communicable Diseases (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9715177A GB9715177D0 (en) | 1997-07-21 | 1997-07-21 | Medicament |
| GB9715177 | 1997-07-21 | ||
| PCT/GB1998/002156 WO1999005169A1 (en) | 1997-07-21 | 1998-07-17 | Epitopes of shigella like toxin and their use as vaccine and in diagnosis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69827800D1 true DE69827800D1 (de) | 2004-12-30 |
| DE69827800T2 DE69827800T2 (de) | 2005-11-24 |
Family
ID=10816080
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69827800T Expired - Lifetime DE69827800T2 (de) | 1997-07-21 | 1998-07-17 | Epitope des shigella-artigen toxins und ihre verwendung als impfstoff und in der diagnose |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6410024B1 (de) |
| EP (1) | EP0998493B1 (de) |
| JP (1) | JP4397523B2 (de) |
| AT (1) | ATE283282T1 (de) |
| AU (1) | AU747197B2 (de) |
| CA (1) | CA2295940C (de) |
| DE (1) | DE69827800T2 (de) |
| ES (1) | ES2234132T3 (de) |
| GB (1) | GB9715177D0 (de) |
| PT (1) | PT998493E (de) |
| WO (1) | WO1999005169A1 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6858211B1 (en) * | 1998-07-20 | 2005-02-22 | The United States Of America As Represented By The Department Of Health And Human Services | Vaccines against Escherichia coli O157 infection |
| EP1295916B1 (de) | 2000-06-07 | 2014-11-26 | Seiko Epson Corporation | Tintenstrahltinte, tintenstrahltintenset, druckmethode, druck sowie tintenstrahlapparatur |
| WO2009088403A2 (en) * | 2007-10-08 | 2009-07-16 | Rutgers, The State University | Nontoxic shiga-like toxin mutant compositions and methods |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5955293A (en) * | 1989-10-17 | 1999-09-21 | New England Medical Center Hospitals, Inc. | Assays for shiga toxin and shiga-like toxins |
| US5552144A (en) * | 1992-01-22 | 1996-09-03 | Microcarb, Inc. | Immunogenic shiga-like toxin II variant mutants |
| WO1993018784A1 (en) * | 1992-03-26 | 1993-09-30 | Microcarb, Inc. | Monospecific polyclonal antibodies to shiga-like toxins |
| US5719064A (en) * | 1992-08-31 | 1998-02-17 | Oklahoma Medical Research Foundation | Peptide diagnostics and therapeutics for spondyloarthropathies |
| US5679564A (en) * | 1994-10-05 | 1997-10-21 | Antex Biologics, Inc. | Methods for producing enhanced antigenic campylobacter bacteria and vaccines |
| WO1996030043A1 (en) | 1995-03-24 | 1996-10-03 | Ophidian Pharmaceuticals | Treatment for verotoxin-producing escherichia coli |
| AU4184597A (en) | 1996-09-10 | 1998-04-02 | Henry M. Jackson Foundation For The Advancement Of Military Medicine | Histidine-tagged shiga toxins, toxoids, and protein fusions with such toxins and toxoids, methods for the purification and preparation thereof |
-
1997
- 1997-07-21 GB GB9715177A patent/GB9715177D0/en active Pending
-
1998
- 1998-07-17 WO PCT/GB1998/002156 patent/WO1999005169A1/en active IP Right Grant
- 1998-07-17 ES ES98935164T patent/ES2234132T3/es not_active Expired - Lifetime
- 1998-07-17 US US09/463,129 patent/US6410024B1/en not_active Expired - Fee Related
- 1998-07-17 JP JP2000504162A patent/JP4397523B2/ja not_active Expired - Fee Related
- 1998-07-17 AU AU84520/98A patent/AU747197B2/en not_active Ceased
- 1998-07-17 DE DE69827800T patent/DE69827800T2/de not_active Expired - Lifetime
- 1998-07-17 CA CA2295940A patent/CA2295940C/en not_active Expired - Fee Related
- 1998-07-17 EP EP98935164A patent/EP0998493B1/de not_active Expired - Lifetime
- 1998-07-17 PT PT98935164T patent/PT998493E/pt unknown
- 1998-07-17 AT AT98935164T patent/ATE283282T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU8452098A (en) | 1999-02-16 |
| EP0998493A1 (de) | 2000-05-10 |
| JP2001510850A (ja) | 2001-08-07 |
| PT998493E (pt) | 2005-03-31 |
| AU747197B2 (en) | 2002-05-09 |
| WO1999005169A1 (en) | 1999-02-04 |
| CA2295940A1 (en) | 1999-02-04 |
| ES2234132T3 (es) | 2005-06-16 |
| CA2295940C (en) | 2010-06-15 |
| US6410024B1 (en) | 2002-06-25 |
| EP0998493B1 (de) | 2004-11-24 |
| GB9715177D0 (en) | 1997-09-24 |
| JP4397523B2 (ja) | 2010-01-13 |
| DE69827800T2 (de) | 2005-11-24 |
| ATE283282T1 (de) | 2004-12-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |