NO975312L - RNA fotospaltning ved bruk av texafyriner - Google Patents

RNA fotospaltning ved bruk av texafyriner

Info

Publication number
NO975312L
NO975312L NO975312A NO975312A NO975312L NO 975312 L NO975312 L NO 975312L NO 975312 A NO975312 A NO 975312A NO 975312 A NO975312 A NO 975312A NO 975312 L NO975312 L NO 975312L
Authority
NO
Norway
Prior art keywords
texaphyrin
cleavage
rna
site
polymer
Prior art date
Application number
NO975312A
Other languages
English (en)
Norwegian (no)
Other versions
NO975312D0 (no
Inventor
Darren Magda
Jonathan L Sessler
Original Assignee
Univ Texas
Pharmacyclics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Texas, Pharmacyclics Inc filed Critical Univ Texas
Publication of NO975312D0 publication Critical patent/NO975312D0/no
Publication of NO975312L publication Critical patent/NO975312L/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0042Photocleavage of drugs in vivo, e.g. cleavage of photolabile linkers in vivo by UV radiation for releasing the pharmacologically-active agent from the administered agent; photothrombosis or photoocclusion
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0497Organic compounds conjugates with a carrier being an organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO975312A 1995-06-07 1997-11-19 RNA fotospaltning ved bruk av texafyriner NO975312L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/484,551 US5714328A (en) 1995-06-07 1995-06-07 RNA photocleavage using texaphyrins
PCT/US1996/009419 WO1996040253A2 (en) 1995-06-07 1996-05-31 Rna photocleavage using texaphyrins

Publications (2)

Publication Number Publication Date
NO975312D0 NO975312D0 (no) 1997-11-19
NO975312L true NO975312L (no) 1998-02-05

Family

ID=23924628

Family Applications (1)

Application Number Title Priority Date Filing Date
NO975312A NO975312L (no) 1995-06-07 1997-11-19 RNA fotospaltning ved bruk av texafyriner

Country Status (14)

Country Link
US (1) US5714328A (de)
EP (1) EP0810878B1 (de)
JP (2) JPH10510844A (de)
KR (1) KR100355251B1 (de)
AT (1) ATE177951T1 (de)
AU (1) AU694051B2 (de)
CA (1) CA2218477C (de)
DE (1) DE69601865T2 (de)
DK (1) DK0810878T3 (de)
ES (1) ES2130826T3 (de)
GR (1) GR3030257T3 (de)
NO (1) NO975312L (de)
NZ (1) NZ310739A (de)
WO (1) WO1996040253A2 (de)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5457183A (en) * 1989-03-06 1995-10-10 Board Of Regents, The University Of Texas System Hydroxylated texaphyrins
US5969111A (en) * 1994-04-14 1999-10-19 Board Of Regents, The University Of Texas System Texaphyrins substituted with imidazole are provided
EP0864002A4 (de) 1995-10-27 1999-07-28 Elliot R Ramberg Verfahren und zusammensetzungen zur erkennung von spezifischen nukleotidsequenzen
US5776925A (en) * 1996-01-25 1998-07-07 Pharmacyclics, Inc. Methods for cancer chemosensitization
US6022959A (en) * 1996-08-20 2000-02-08 Pharmacyclics, Inc. Nucleic acids internally-derivatized with a texaphyrin metal complex and uses thereof
WO1998051818A1 (en) * 1997-05-14 1998-11-19 Khrapunov Volodymyr Mykolaiovy Method for treatment of deoxyribonucleic acid sequence by restrictase
US6022526A (en) * 1997-07-30 2000-02-08 Pharmacyclics, Inc. Use of texaphyrins in detection of melanin and melanin metabolites diagnostic of melanotic melanoma
US7498156B2 (en) * 1998-07-21 2009-03-03 Caridianbct Biotechnologies, Llc Use of visible light at wavelengths of 500 to 550 nm to reduce the number of pathogens in blood and blood components
US20070099170A1 (en) * 1998-07-21 2007-05-03 Navigant Biotechnologies, Inc. Method for treatment and storage of blood and blood products using endogenous alloxazines and acetate
US6277337B1 (en) 1998-07-21 2001-08-21 Gambro, Inc. Method and apparatus for inactivation of biological contaminants using photosensitizers
US6258577B1 (en) 1998-07-21 2001-07-10 Gambro, Inc. Method and apparatus for inactivation of biological contaminants using endogenous alloxazine or isoalloxazine photosensitizers
US7049110B2 (en) * 1998-07-21 2006-05-23 Gambro, Inc. Inactivation of West Nile virus and malaria using photosensitizers
JP4207258B2 (ja) * 1998-08-31 2009-01-14 東ソー株式会社 特定核酸配列の切断方法
US6284220B1 (en) * 1999-06-03 2001-09-04 The General Hospital Corporation Noninvasive imaging of nucleic acid vectors
US7220747B2 (en) * 1999-07-20 2007-05-22 Gambro, Inc. Method for preventing damage to or rejuvenating a cellular blood component using mitochondrial enhancer
US6268120B1 (en) 1999-10-19 2001-07-31 Gambro, Inc. Isoalloxazine derivatives to neutralize biological contaminants
US7985588B2 (en) * 2000-06-02 2011-07-26 Caridianbct Biotechnologies, Llc Induction of and maintenance of nucleic acid damage in pathogens using riboflavin and light
TW590780B (en) * 2000-06-02 2004-06-11 Gambro Inc Additive solutions containing riboflavin
US7648699B2 (en) * 2000-06-02 2010-01-19 Caridianbct Biotechnologies, Llc Preventing transfusion related complications in a recipient of a blood transfusion
US6843961B2 (en) * 2000-06-15 2005-01-18 Gambro, Inc. Reduction of contaminants in blood and blood products using photosensitizers and peak wavelengths of light
US9044523B2 (en) 2000-06-15 2015-06-02 Terumo Bct, Inc. Reduction of contaminants in blood and blood products using photosensitizers and peak wavelengths of light
WO2002017925A1 (en) * 2000-08-30 2002-03-07 Pharmacyclics, Inc. Non-symmetric tripyrrannes in the synthesis of novel macrocycles
US7449454B2 (en) * 2000-08-30 2008-11-11 Pharmacyclics, Inc. Metallotexaphyrin derivatives
US6638924B2 (en) 2000-08-30 2003-10-28 Pharmacyclics, Inc. Metallotexaphyrin derivatives
WO2002048399A2 (de) * 2000-12-13 2002-06-20 Institut für Physikalische Hochtechnologie e.V. Verfahren zum simultanen positionsspezifischen schneiden von fadenförmigen organischen molekülketten, insbesonere dna
US20030228564A1 (en) * 2001-05-30 2003-12-11 Edrich Richard Alan Nitric oxide in a pathogen inactivation process
WO2003072581A1 (en) 2002-02-26 2003-09-04 Board Of Regents, The University Of Texas System Cyclo[n]pyrroles and methods thereto
US6723750B2 (en) 2002-03-15 2004-04-20 Allergan, Inc. Photodynamic therapy for pre-melanomas
JP2006224318A (ja) * 2005-02-15 2006-08-31 Brother Ind Ltd インクジェット記録装置
US20070072838A1 (en) 2005-09-26 2007-03-29 Pharmacyclics, Inc. High-purity texaphyrin metal complexes
US20070078119A1 (en) * 2005-09-30 2007-04-05 Pharmacyclics, Inc. Storage system for texaphyrin pharmaceutical formulations
US8133474B2 (en) * 2006-09-15 2012-03-13 Massachusetts Institute Of Technology Sensors for fluorescence and magnetic resonance imaging
US20140127077A1 (en) 2012-11-05 2014-05-08 Gail Rock Device and method for sterilization of instruments and surfaces

Family Cites Families (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4318825A (en) * 1979-08-15 1982-03-09 Frame Robert R Catalytic composite, and method of manufacture
US4647447A (en) * 1981-07-24 1987-03-03 Schering Aktiengesellschaft Diagnostic media
US4957939A (en) * 1981-07-24 1990-09-18 Schering Aktiengesellschaft Sterile pharmaceutical compositions of gadolinium chelates useful enhancing NMR imaging
US4613322A (en) * 1982-12-08 1986-09-23 Edelson Richard Leslie Method and system for externally treating the blood
FR2540122B1 (fr) * 1983-01-27 1985-11-29 Centre Nat Rech Scient Nouveaux composes comportant une sequence d'oligonucleotide liee a un agent d'intercalation, leur procede de synthese et leur application
JPS61275228A (ja) * 1985-03-14 1986-12-05 バクスタ−、トラベノ−ル、ラボラトリ−ズ、インコ−ポレイテツド 治療用タンパク組成物中のビ−ルスの光動的不活性化
US4977177A (en) * 1985-04-30 1990-12-11 Nippon Petrochemicals Company, Ltd. Tetrapyrrole polyaminomonocarboxylic acid therapeutic agents
US4899755A (en) * 1985-05-08 1990-02-13 The General Hospital Corporation Hepatobiliary NMR contrast agents
US4880008A (en) * 1985-05-08 1989-11-14 The General Hospital Corporation Vivo enhancement of NMR relaxivity
FR2586704B1 (fr) * 1985-09-04 1987-12-18 Centre Nat Rech Scient Nouveaux composes comportant une sequence d'oligonucleotide liee a un agent d'intercalation et a un groupe chimique activable, leur synthese et leurs applications a titre de nucleases artificielles specifiques de sequences. centre national de la recherche scientifique (cnrs)
US4772681A (en) * 1986-01-17 1988-09-20 Hamari Chemicals, Ltd. Porphyrin derivatives
US5242797A (en) * 1986-03-21 1993-09-07 Myron J. Block Nucleic acid assay method
US4915683A (en) * 1986-11-21 1990-04-10 The Medical College Of Wisconsin, Inc. Antiviral method, agents and apparatus
US5135717A (en) * 1986-12-24 1992-08-04 British Technology Group Usa Inc. Tetrabenztriazaporphyrin reagents and kits containing the same
US4883790A (en) * 1987-01-20 1989-11-28 University Of British Columbia Wavelength-specific cytotoxic agents
US4878891A (en) * 1987-06-25 1989-11-07 Baylor Research Foundation Method for eradicating infectious biological contaminants in body tissues
WO1990001208A1 (en) * 1988-07-28 1990-02-08 Best Industries, Inc. Device and method for encapsulating radioactive materials
EP0434727A4 (en) * 1988-09-08 1994-08-17 Ultra Diagnostic Corp Red-shifted phthalocyanine and tetrabenztriazaporphyrin reagents
US5599923A (en) * 1989-03-06 1997-02-04 Board Of Regents, University Of Tx Texaphyrin metal complexes having improved functionalization
US5256399A (en) * 1989-03-06 1993-10-26 Board Of Regents, The University Of Texas System Aromatic pentadentate expanded porphyrins in magnetic resonance imaging
US5162509A (en) * 1989-03-06 1992-11-10 Board Of Regents, The University Of Texas System Process for preparing expanded porphyrins: large porphyrin-like tripyrroledimethine-derived macrocycles
US5041078A (en) * 1989-03-06 1991-08-20 Baylor Research Foundation, A Nonprofit Corporation Of The State Of Texas Photodynamic viral deactivation with sapphyrins
US5252720A (en) * 1989-03-06 1993-10-12 Board Of Regents, The University Of Texas System Metal complexes of water soluble texaphyrins
US5559207A (en) * 1989-03-06 1996-09-24 Board Of Regents, University Of Texas Texaphyrin metal complex mediated ester hydrolysis
US5457183A (en) * 1989-03-06 1995-10-10 Board Of Regents, The University Of Texas System Hydroxylated texaphyrins
US5272142A (en) * 1989-03-06 1993-12-21 Board Of Regents, The University Of Texas System Expanded porphyrins: large porphyrin-like tripyrroledimethine-derived macrocycles and methods for treating tumors
US4935498A (en) * 1989-03-06 1990-06-19 Board Of Regents, The University Of Texas System Expanded porphyrins: large porphyrin-like tripyrroledimethine-derived macrocycles
US4959363A (en) * 1989-06-23 1990-09-25 Sterling Drug Inc. Quinolonecarboxamide compounds, their preparation and use as antivirals.
FR2650761B1 (fr) * 1989-08-10 1994-03-04 Elf Aquitaine Ste Nale Catalyseur d'oxydation a base de metalloporphyrine sur support
US5219732A (en) * 1989-09-05 1993-06-15 The Regents Of The University Of California Antibody-mediated cofactor-driven reactions
US5159065A (en) * 1989-12-21 1992-10-27 Board Of Regents, The University Of Texas System Sapphyrins, derivatives and syntheses
US5457195A (en) * 1989-12-21 1995-10-10 Board Of Regents, The University Of Texas System Sapphyrin derivatives and conjugates
WO1991019730A1 (en) * 1990-06-14 1991-12-26 Monsanto Company Rna hydrolysis/cleavage
US5272056A (en) * 1991-01-03 1993-12-21 The Research Foundation Of State University Of New York Modification of DNA and oligonucleotides using metal complexes of polyaza ligands
US5607924A (en) * 1992-01-21 1997-03-04 Pharmacyclics, Inc. DNA photocleavage using texaphyrins
US5371199B1 (en) * 1992-08-14 1995-12-26 Univ Pennsylvania Substituted porphyrins porphyrin-containing polymers and synthetic methods therefor
FR2697254A1 (fr) * 1992-10-22 1994-04-29 Genset Sa Conjugués constitués par un oligonucléotide lié à des dérivés de métalloporphyrine cationique, leur préparation et leur utilisation.
WO1995029702A1 (en) * 1994-04-28 1995-11-09 Board Of Regents, The University Of Texas System Texaphyrin solid-supports and devices
WO1996007667A1 (de) * 1994-09-02 1996-03-14 Novartis Ag Oligonukleotidkonjugate, zusammensetzungen und verfahren zur spaltung von ribonukleinsäuren

Also Published As

Publication number Publication date
KR100355251B1 (ko) 2003-02-17
AU6159096A (en) 1996-12-30
WO1996040253A3 (en) 1997-01-23
JP2001316270A (ja) 2001-11-13
NO975312D0 (no) 1997-11-19
ATE177951T1 (de) 1999-04-15
ES2130826T3 (es) 1999-07-01
DK0810878T3 (da) 1999-10-11
EP0810878A2 (de) 1997-12-10
NZ310739A (en) 2000-09-29
EP0810878B1 (de) 1999-03-24
GR3030257T3 (en) 1999-08-31
KR19980701473A (ko) 1998-05-15
CA2218477C (en) 2002-10-22
AU694051B2 (en) 1998-07-09
WO1996040253A2 (en) 1996-12-19
DE69601865D1 (de) 1999-04-29
DE69601865T2 (de) 1999-08-05
US5714328A (en) 1998-02-03
CA2218477A1 (en) 1996-12-19
JPH10510844A (ja) 1998-10-20

Similar Documents

Publication Publication Date Title
NO975312D0 (no) RNA fotospaltning ved bruk av texafyriner
Knorre et al. Complementary-addressed (sequence-specific) modification of nucleic acids
Peck-Miller et al. Kinetics of the processing of the precursor to 4· 5 S RNA, a naturally occurring substrate for RNase P from Escherichia coli
Knapp et al. Splicing of yeast tRNA precursors: structure of the reaction intermediates
EP0967274A3 (de) Verfahren zur Reinigung von kovalent geschlossenen DNA-Molekülen
Giovannangeli et al. Oligodeoxynucleotide-directed photo-induced cross-linking of HIV proviral DNA via triple-helix formation
Pratviel et al. Nonenzymic cleavage and ligation of DNA at a three A. cntdot. T base pair site. A two-step pseudohydrolysis of DNA
WO1994029316A3 (en) Texaphyrin metal complex mediated ester hydrolysis
UA49843C2 (uk) Олігонуклеотид для ампліфікації послідовностей нуклеїнових кислот, спосіб ампліфікації цільової послідовності нуклеїнової кислоти, набір для здійснення реакції ампліфікації нуклеїнової кислоти
EP1602725A3 (de) Enzymatische Nukleinsäure die Abasische Nukleotide enthaltet
Jones et al. Dual action of tirapazamine in the induction of DNA strand breaks
PL305762A1 (en) Microwave modification of biological macromolecules
Rabin et al. Analysis of RNA secondary structure by photochemical reversal of psoralen crosslinks
BUDOWSKY et al. Induction of polynucleotide‐protein cross‐linkages by ultraviolet irradiation: Peculiarities of the high‐intensity laser pulse irradiation
Liuzzi et al. Enzymatic Analysis of Isomeric Trithymidylates Containing Ultraviolet Light-induced Cyclobutane Pyrimidine Dimers: I. Nuclease P1-mediated hydrolysis of the intradimer phosphodiester linkage
WO1998054313A3 (en) Dna methyltransferase genomic sequences and antisense oligonucleotides
Kleineidam et al. Efficient cleavage of pre-tRNAs by E. coli RNAse P RNA requires the 2′-hydroxyl of the ribose at the cleavage site
EP1006200A3 (de) Verfahren zur Herstellung von ausgewählten intermolekularen in Nukleinsäuren und ihre Verwendungen
Carriero et al. Template-mediated synthesis of lariat RNA and DNA
Von Sonntag Radiation chemistry in the 1990s: pressing questions relating to the areas of radiation biology and environmental research
Markham et al. Rapid chemical synthesis and circular dichroism properties of some 2′-5′-linked oligoriboadenylates
Bull et al. Inactivation of E. coli RNA polymerase by pyridoxal 5′-phosphate: Identification of a low pKa lysine as the modified residue
Krakowiak et al. Stereochemical course of Escherichia coli RNase H
Küpfer et al. RNA Abasic Sites: Preparation and Trans‐Lesion Synthesis by HIV‐1 Reverse Transcriptase
Krauskopf et al. The function of pseudouridylic acid in transfer ribonucleic acid. Irradiation and cyanoethylation of E. coli valine tRNA fragments