NO972731L - Thiazolidinonforbindelser og terapeutisk eller forhindrende middel mot angina pectoris omfattende forbindelsene som aktiv bestanddel - Google Patents

Thiazolidinonforbindelser og terapeutisk eller forhindrende middel mot angina pectoris omfattende forbindelsene som aktiv bestanddel

Info

Publication number
NO972731L
NO972731L NO972731A NO972731A NO972731L NO 972731 L NO972731 L NO 972731L NO 972731 A NO972731 A NO 972731A NO 972731 A NO972731 A NO 972731A NO 972731 L NO972731 L NO 972731L
Authority
NO
Norway
Prior art keywords
group
compounds
alkyl group
angina pectoris
atom
Prior art date
Application number
NO972731A
Other languages
English (en)
Other versions
NO972731D0 (no
NO309475B1 (no
Inventor
Sadao Ishihara
Fujio Saito
Yasuo Ohhata
Shigeki Miyake
Ryosuke Yorikane
Norio Fukuda
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co filed Critical Sankyo Co
Publication of NO972731D0 publication Critical patent/NO972731D0/no
Publication of NO972731L publication Critical patent/NO972731L/no
Publication of NO309475B1 publication Critical patent/NO309475B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/14—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/30—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Vascular Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Urology & Nephrology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO972731A 1994-12-15 1997-06-13 Tiazolidinonforbindelser og terapeutisk eller forhindrende middel mot angina pectoris omfattende forbindelsene som aktiv bestanddel NO309475B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP31151194 1994-12-15
PCT/JP1995/002545 WO1996018620A1 (en) 1994-12-15 1995-12-13 Thiazolidinone compounds or angina pectoris remedy or preventive containing the same as active ingredient

Publications (3)

Publication Number Publication Date
NO972731D0 NO972731D0 (no) 1997-06-13
NO972731L true NO972731L (no) 1997-08-14
NO309475B1 NO309475B1 (no) 2001-02-05

Family

ID=18018119

Family Applications (1)

Application Number Title Priority Date Filing Date
NO972731A NO309475B1 (no) 1994-12-15 1997-06-13 Tiazolidinonforbindelser og terapeutisk eller forhindrende middel mot angina pectoris omfattende forbindelsene som aktiv bestanddel

Country Status (20)

Country Link
US (1) US5843973A (no)
EP (1) EP0798298B1 (no)
KR (1) KR100312471B1 (no)
CN (1) CN1092649C (no)
AT (1) ATE203987T1 (no)
AU (1) AU692334B2 (no)
CA (1) CA2207794A1 (no)
CZ (1) CZ292626B6 (no)
DE (1) DE69522118T2 (no)
DK (1) DK0798298T3 (no)
ES (1) ES2161916T3 (no)
FI (1) FI972510A7 (no)
GR (1) GR3036704T3 (no)
HU (1) HUT77131A (no)
MX (1) MX9704435A (no)
NO (1) NO309475B1 (no)
NZ (1) NZ297095A (no)
PT (1) PT798298E (no)
RU (1) RU2139283C1 (no)
WO (1) WO1996018620A1 (no)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200524849A (en) * 2003-07-02 2005-08-01 Hoffmann La Roche Hydroxyalkylamide derivatives
AU2004291539A1 (en) 2003-11-18 2005-06-02 Ohio State University Research Foundation Thiazolidinone amides, thiazolidine carboxylic acid amides, methods of making, and uses thereof
DK2303021T3 (en) 2008-06-16 2019-04-08 Univ Tennessee Res Found RELATIONSHIPS FOR TREATING CANCER
US9029408B2 (en) 2008-06-16 2015-05-12 Gtx, Inc. Compounds for treatment of cancer
US8822513B2 (en) 2010-03-01 2014-09-02 Gtx, Inc. Compounds for treatment of cancer
US9447049B2 (en) 2010-03-01 2016-09-20 University Of Tennessee Research Foundation Compounds for treatment of cancer
EP2290114A1 (de) 2009-08-04 2011-03-02 Gebr. Kemper GmbH + Co. KG Metallwerke Wasserführendes Bauteil
KR101939704B1 (ko) 2010-03-01 2019-01-17 지티엑스, 인코포레이티드 암 치료용 화합물

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5213910A (en) * 1975-07-19 1977-02-02 Toshinori Kawabuchi Photogravure printing press
GB8717068D0 (en) * 1987-07-20 1987-08-26 Fujisawa Pharmaceutical Co Nitric ester derivative
US5298516A (en) * 1991-03-27 1994-03-29 Sankyo Company, Limited Thiazolidone compounds and method of using the same as a vasodilator
CZ290989B6 (cs) * 1995-03-02 2002-11-13 Sankyo Company, Limited Opticky aktivní thiazolidinonový derivát, prostředek jej obsahující, pouľití tohoto derivátu a způsob jeho přípravy

Also Published As

Publication number Publication date
HK1000494A1 (en) 2002-03-15
DE69522118D1 (de) 2001-09-13
AU4187996A (en) 1996-07-03
PT798298E (pt) 2001-11-30
ES2161916T3 (es) 2001-12-16
EP0798298B1 (en) 2001-08-08
WO1996018620A1 (en) 1996-06-20
CN1092649C (zh) 2002-10-16
DK0798298T3 (da) 2001-10-22
HUT77131A (hu) 1998-03-02
EP0798298A4 (en) 1998-03-25
CN1175250A (zh) 1998-03-04
GR3036704T3 (en) 2001-12-31
US5843973A (en) 1998-12-01
NO972731D0 (no) 1997-06-13
NO309475B1 (no) 2001-02-05
CZ183497A3 (en) 1997-12-17
RU2139283C1 (ru) 1999-10-10
AU692334B2 (en) 1998-06-04
KR100312471B1 (ko) 2002-02-28
CA2207794A1 (en) 1996-06-20
EP0798298A1 (en) 1997-10-01
ATE203987T1 (de) 2001-08-15
FI972510A0 (fi) 1997-06-13
FI972510A7 (fi) 1997-08-07
DE69522118T2 (de) 2002-04-25
MX9704435A (es) 1997-10-31
CZ292626B6 (cs) 2003-11-12
NZ297095A (en) 1998-09-24

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