NO972731L - Thiazolidinonforbindelser og terapeutisk eller forhindrende middel mot angina pectoris omfattende forbindelsene som aktiv bestanddel - Google Patents

Thiazolidinonforbindelser og terapeutisk eller forhindrende middel mot angina pectoris omfattende forbindelsene som aktiv bestanddel

Info

Publication number
NO972731L
NO972731L NO972731A NO972731A NO972731L NO 972731 L NO972731 L NO 972731L NO 972731 A NO972731 A NO 972731A NO 972731 A NO972731 A NO 972731A NO 972731 L NO972731 L NO 972731L
Authority
NO
Norway
Prior art keywords
group
compounds
alkyl group
angina pectoris
atom
Prior art date
Application number
NO972731A
Other languages
English (en)
Other versions
NO309475B1 (no
NO972731D0 (no
Inventor
Sadao Ishihara
Fujio Saito
Yasuo Ohhata
Shigeki Miyake
Ryosuke Yorikane
Norio Fukuda
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co filed Critical Sankyo Co
Publication of NO972731D0 publication Critical patent/NO972731D0/no
Publication of NO972731L publication Critical patent/NO972731L/no
Publication of NO309475B1 publication Critical patent/NO309475B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18Oxygen atoms
    • C07D263/20Oxygen atoms attached in position 2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D277/12Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/14Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/30Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Vascular Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Urology & Nephrology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO972731A 1994-12-15 1997-06-13 Tiazolidinonforbindelser og terapeutisk eller forhindrende middel mot angina pectoris omfattende forbindelsene som aktiv bestanddel NO309475B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP31151194 1994-12-15
PCT/JP1995/002545 WO1996018620A1 (fr) 1994-12-15 1995-12-13 Composes thiazolidinone ou medicament pour prevenir ou guerir l'angine de poitrine contenant ces composes en tant qu'ingredient actif

Publications (3)

Publication Number Publication Date
NO972731D0 NO972731D0 (no) 1997-06-13
NO972731L true NO972731L (no) 1997-08-14
NO309475B1 NO309475B1 (no) 2001-02-05

Family

ID=18018119

Family Applications (1)

Application Number Title Priority Date Filing Date
NO972731A NO309475B1 (no) 1994-12-15 1997-06-13 Tiazolidinonforbindelser og terapeutisk eller forhindrende middel mot angina pectoris omfattende forbindelsene som aktiv bestanddel

Country Status (21)

Country Link
US (1) US5843973A (no)
EP (1) EP0798298B1 (no)
KR (1) KR100312471B1 (no)
CN (1) CN1092649C (no)
AT (1) ATE203987T1 (no)
AU (1) AU692334B2 (no)
CA (1) CA2207794A1 (no)
CZ (1) CZ292626B6 (no)
DE (1) DE69522118T2 (no)
DK (1) DK0798298T3 (no)
ES (1) ES2161916T3 (no)
FI (1) FI972510A (no)
GR (1) GR3036704T3 (no)
HK (1) HK1000494A1 (no)
HU (1) HUT77131A (no)
MX (1) MX9704435A (no)
NO (1) NO309475B1 (no)
NZ (1) NZ297095A (no)
PT (1) PT798298E (no)
RU (1) RU2139283C1 (no)
WO (1) WO1996018620A1 (no)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200524849A (en) * 2003-07-02 2005-08-01 Hoffmann La Roche Hydroxyalkylamide derivatives
JP2007513090A (ja) 2003-11-18 2007-05-24 ユニバーシティ オブ テネシー リサーチ ファウンデーション チアゾリジノンアミド、チアゾリジンカルボン酸アミド、その製造方法、およびその使用方法
US9029408B2 (en) 2008-06-16 2015-05-12 Gtx, Inc. Compounds for treatment of cancer
US9447049B2 (en) 2010-03-01 2016-09-20 University Of Tennessee Research Foundation Compounds for treatment of cancer
US8822513B2 (en) 2010-03-01 2014-09-02 Gtx, Inc. Compounds for treatment of cancer
RU2514427C2 (ru) 2008-06-16 2014-04-27 Юниверсити Оф Теннесси Рисёч Фаундейшн Соединения для лечения рака
EP2290114A1 (de) 2009-08-04 2011-03-02 Gebr. Kemper GmbH + Co. KG Metallwerke Wasserführendes Bauteil
AU2010347233B2 (en) 2010-03-01 2015-06-18 Oncternal Therapeutics, Inc. Compounds for treatment of cancer

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5213910A (en) * 1975-07-19 1977-02-02 Toshinori Kawabuchi Photogravure printing press
GB8717068D0 (en) * 1987-07-20 1987-08-26 Fujisawa Pharmaceutical Co Nitric ester derivative
US5298516A (en) * 1991-03-27 1994-03-29 Sankyo Company, Limited Thiazolidone compounds and method of using the same as a vasodilator
CA2214386C (en) * 1995-03-02 2001-12-04 Sadao Ishihara Optically active thiazolidinone derivatives

Also Published As

Publication number Publication date
EP0798298A1 (en) 1997-10-01
CZ183497A3 (en) 1997-12-17
DE69522118D1 (de) 2001-09-13
CN1092649C (zh) 2002-10-16
ES2161916T3 (es) 2001-12-16
AU692334B2 (en) 1998-06-04
FI972510A (fi) 1997-08-07
US5843973A (en) 1998-12-01
HK1000494A1 (en) 2002-03-15
EP0798298B1 (en) 2001-08-08
NO309475B1 (no) 2001-02-05
PT798298E (pt) 2001-11-30
RU2139283C1 (ru) 1999-10-10
CA2207794A1 (en) 1996-06-20
ATE203987T1 (de) 2001-08-15
NZ297095A (en) 1998-09-24
EP0798298A4 (en) 1998-03-25
KR100312471B1 (ko) 2002-02-28
NO972731D0 (no) 1997-06-13
MX9704435A (es) 1997-10-31
CZ292626B6 (cs) 2003-11-12
HUT77131A (hu) 1998-03-02
GR3036704T3 (en) 2001-12-31
CN1175250A (zh) 1998-03-04
FI972510A0 (fi) 1997-06-13
AU4187996A (en) 1996-07-03
DE69522118T2 (de) 2002-04-25
DK0798298T3 (da) 2001-10-22
WO1996018620A1 (fr) 1996-06-20

Similar Documents

Publication Publication Date Title
DK0976748T3 (da) Pyrrolidinderivater med phospholispase A2-hæmmende aktivitet
DK1043317T3 (da) Pyridazinderivater og medikamenter indeholdende dem som aktiv bestanddel
CA2311742A1 (en) 6-amino-9-benzyl-8-hydroxypurine derivatives
CA2080917A1 (en) New pharmacologically active catechol derivatives
NO20000722L (no) 2-(4-aryl eller heteroaryl-piperazin-1-ylmetyl)-1H- indolderivater
DK0916651T3 (da) Phenylalkylcarboxylsyrederivater
NO972731L (no) Thiazolidinonforbindelser og terapeutisk eller forhindrende middel mot angina pectoris omfattende forbindelsene som aktiv bestanddel
DE69415314D1 (de) Neue bisoxadiazolidinderivate
DK0506434T3 (da) Thiazolidinon- og oxazolidinon-derivater, fremstilling deraf og deres anvendelse som vasodilaterende midler
ATE201402T1 (de) Optisch aktive thiazolidinonderivate
NO305163B1 (no) Aminosyrederivater samt terapeutisk middel mot angina pectoris som omfatter et slikt
NO20000750D0 (no) Fremgangsmåte for å redusere blodplatetall
TH14432A (th) สารยับยั้ง hiv โปรตีเอสที่เป็นประโยชน์สำหรับการบำบัดเอดส์
TH14432EX (th) สารยับยั้ง hiv โปรตีเอสที่เป็นประโยชน์สำหรับการบำบัดเอดส์