NO972222L - Bicykliske oxazin- og thiazinoxazolidinon-antibakterielle midler - Google Patents

Bicykliske oxazin- og thiazinoxazolidinon-antibakterielle midler

Info

Publication number
NO972222L
NO972222L NO972222A NO972222A NO972222L NO 972222 L NO972222 L NO 972222L NO 972222 A NO972222 A NO 972222A NO 972222 A NO972222 A NO 972222A NO 972222 L NO972222 L NO 972222L
Authority
NO
Norway
Prior art keywords
pct
date
spp
mycobacterium
oxazine
Prior art date
Application number
NO972222A
Other languages
English (en)
Norwegian (no)
Other versions
NO972222D0 (no
Inventor
Michael Robert Barbachyn
Richard Charles Thomas
Gary J Cleek
Lisa Marie Thomasco
Robert C Gadwood
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of NO972222D0 publication Critical patent/NO972222D0/no
Publication of NO972222L publication Critical patent/NO972222L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/08—Bridged systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO972222A 1994-11-15 1997-05-14 Bicykliske oxazin- og thiazinoxazolidinon-antibakterielle midler NO972222L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33997994A 1994-11-15 1994-11-15
PCT/US1995/012751 WO1996015130A1 (en) 1994-11-15 1995-10-31 Bicyclic oxazine and thiazine oxazolidinone antibacterials

Publications (2)

Publication Number Publication Date
NO972222D0 NO972222D0 (no) 1997-05-14
NO972222L true NO972222L (no) 1997-05-14

Family

ID=23331388

Family Applications (1)

Application Number Title Priority Date Filing Date
NO972222A NO972222L (no) 1994-11-15 1997-05-14 Bicykliske oxazin- og thiazinoxazolidinon-antibakterielle midler

Country Status (17)

Country Link
US (1) US5952324A (zh)
EP (1) EP0792273B1 (zh)
JP (1) JPH10508844A (zh)
KR (1) KR100392216B1 (zh)
CN (1) CN1046520C (zh)
AT (1) ATE233766T1 (zh)
AU (1) AU702733B2 (zh)
BR (1) BR9509673A (zh)
DE (1) DE69529838T2 (zh)
DK (1) DK0792273T3 (zh)
ES (1) ES2193201T3 (zh)
MX (1) MX9703543A (zh)
NO (1) NO972222L (zh)
NZ (1) NZ295528A (zh)
PT (1) PT792273E (zh)
RU (1) RU2128660C1 (zh)
WO (1) WO1996015130A1 (zh)

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JPH11512429A (ja) * 1995-09-15 1999-10-26 ファルマシア・アンド・アップジョン・カンパニー アミノアリールオキサゾリジノン ｎ−オキシド
ZA968661B (en) * 1995-11-17 1998-04-14 Upjohn Co Oxazolidinone antibacterial agent with tricyclic substituents.
GB9601666D0 (en) * 1996-01-27 1996-03-27 Zeneca Ltd Chemical compounds
GB9702213D0 (en) 1996-02-24 1997-03-26 Zeneca Ltd Chemical compounds
CZ200788A3 (cs) * 1996-04-11 2017-01-25 Pfizer Inc. Způsob přípravy 5-aminomethyl substituovaných oxazolidinonaminů
GB9609919D0 (en) * 1996-05-11 1996-07-17 Zeneca Ltd Chemical compounds
KR100307211B1 (ko) * 1997-05-24 2001-11-30 손 경 식 옥사졸리디논유도체,이의제조방법및그를함유한항균제조성물
GB9717807D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
GB9717804D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
KR100467309B1 (ko) * 1997-09-04 2005-07-18 씨제이 주식회사 옥사졸리디논유도체및그의제조방법및항균제조성물
KR100463111B1 (ko) * 1997-10-30 2005-06-13 씨제이 주식회사 신규한옥사졸리디논유도체및제조방법및그를함유하는항균제조성물
GB9725244D0 (en) 1997-11-29 1998-01-28 Zeneca Ltd Chemical compounds
EP1082323A2 (en) 1998-06-05 2001-03-14 AstraZeneca UK Limited Oxazolidinone derivatives, process for their preparation and pharmaceutical compositions containing them
US6608081B2 (en) 1999-08-12 2003-08-19 Ortho-Mcneil Pharmaceutical, Inc. Bicyclic heterocyclic substituted phenyl oxazolidinone antibacterials, and related compositions and methods
US6413981B1 (en) * 1999-08-12 2002-07-02 Ortho-Mcneil Pharamceutical, Inc. Bicyclic heterocyclic substituted phenyl oxazolidinone antibacterials, and related compositions and methods
GB9928568D0 (en) 1999-12-03 2000-02-02 Zeneca Ltd Chemical compounds
SK7572002A3 (en) * 1999-12-21 2002-12-03 Upjohn Co Oxazolidinones having a sulfoximine functionality and their use as antimicrobial agents
US6518285B2 (en) 1999-12-21 2003-02-11 Ortho Mcneil Pharmaceutical, Inc. Piperidinyloxy and pyrrolidinyloxy oxazolidinone antibacterials
GB0009803D0 (en) * 2000-04-25 2000-06-07 Astrazeneca Ab Chemical compounds
DE60118241T2 (de) 2000-10-17 2006-12-28 Pharmacia & Upjohn Co. Llc, Kalamazoo Verfahren zur herstellung von oxazolidinonverbindungen
ES2268011T3 (es) * 2001-04-07 2007-03-16 Astrazeneca Ab Oxazolidinonas que contienen un grupo sulfonimida como antibioticos.
GB0108793D0 (en) * 2001-04-07 2001-05-30 Astrazeneca Ab Chemical compounds
NZ528996A (en) * 2001-04-20 2006-01-27 Upjohn Co Process to prepare oxazolidinones
TW200302095A (en) * 2002-01-25 2003-08-01 Upjohn Co Oxazolidinone cotherapy
AR038536A1 (es) * 2002-02-25 2005-01-19 Upjohn Co N-aril-2-oxazolidinona-5- carboxamidas y sus derivados
US7141588B2 (en) 2002-02-25 2006-11-28 Pfizer, Inc. N-aryl-2-oxazolidinone-5-carboxamides and their derivatives
WO2003084534A1 (en) * 2002-03-29 2003-10-16 Pharmacia & Upjohn Company Llc Parenteral, intravenous, and oral administration of oxazolidinones for treating diabetic foot infections
JP2005537301A (ja) * 2002-08-12 2005-12-08 ファルマシア・アンド・アップジョン・カンパニー・エルエルシー Ｎ−アリール−２−オキサゾリジノン類及びそれらの誘導体
AR042086A1 (es) 2002-11-21 2005-06-08 Upjohn Co N-aril-2- oxazolidinon -5- carboxamidas y sus derivados, usados como agentes antibacterianos
JP2006516991A (ja) * 2003-02-07 2006-07-13 ワーナー−ランバート・カンパニー、リミテッド、ライアビリティ、カンパニー 抗菌剤
MXPA05007937A (es) * 2003-02-07 2005-09-30 Warner Lambert Co Agentes antibacterianos.
US20040204463A1 (en) * 2003-04-01 2004-10-14 Harris Christina Renee N-aryl-2-oxazolidinone-5-carboxamides and their derivatives
US7304050B2 (en) * 2003-09-16 2007-12-04 Pfizer Inc. Antibacterial agents
ZA200610270B (en) * 2004-05-17 2008-06-25 Acadia Pharm Inc Androgen receptor modulators and method of treating disease using the same
US20070004679A1 (en) * 2004-05-17 2007-01-04 Nathalie Schlienger Androgen receptor modulators and methods of treating disease using the same
US20050261278A1 (en) 2004-05-21 2005-11-24 Weiner David M Selective serotonin receptor inverse agonists as therapeutics for disease
AP2007003904A0 (en) * 2004-08-06 2007-02-28 Pharmacia & Upjohn Co Llc Oxazolidinones containing oxindoles as antibacterial agents
EP2302078B1 (en) 2004-11-03 2015-07-15 Iris Molecular Diagnostics, Inc. Microbubbles for affinity concentration
US8338579B2 (en) 2004-11-03 2012-12-25 Iris Molecular Diagnostics, Inc. Homogeneous analyte detection
US20060173037A1 (en) * 2005-01-10 2006-08-03 Nathalie Schlienger Aminophenyl derivatives as selective androgen receptor modulators
CA2594340C (en) * 2005-01-10 2015-11-10 Acadia Pharmaceuticals Inc. Aminophenyl derivatives as selective androgen receptor modulators
ATE449773T1 (de) 2005-06-29 2009-12-15 Pharmacia & Upjohn Co Llc Homomorpholinoxazolidinone als antibakterielle mittel
AU2009228293B2 (en) * 2008-03-26 2012-11-08 Tennor Therapeutics (Suzhou) Limited Bicyclic nitroimidazoles covalently linked to substituted phenyl oxazolidinones
EP4074378A1 (en) 2015-07-02 2022-10-19 Janssen Sciences Ireland Unlimited Company Antibacterial compounds
CA2990260A1 (en) * 2015-07-17 2017-01-26 The Global Alliance For Tb Drug Development, Inc. Substituted phenyloxazolidinones for antimicrobial therapy
CN109476657A (zh) 2016-06-16 2019-03-15 爱尔兰詹森科学公司 作为抗细菌剂的杂环化合物
BR112019017901A2 (pt) 2017-03-01 2020-05-12 Janssen Sciences Ireland Unlimited Company Terapia de combinação
WO2020147504A1 (en) * 2019-01-18 2020-07-23 Merck Sharp & Dohme Corp. Oxazolidinone compounds and methods of use thereof as antibacterial agents
WO2020234636A1 (en) 2019-05-17 2020-11-26 Cadila Healthcare Limited Novel compounds for the treatment of mammalian infections

Family Cites Families (11)

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Publication number Priority date Publication date Assignee Title
US4921869A (en) * 1987-10-09 1990-05-01 E. I. Du Pont De Nemours And Company Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents
US4801600A (en) * 1987-10-09 1989-01-31 E. I. Du Pont De Nemours And Company Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents
CA1320730C (en) * 1987-10-16 1993-07-27 The Du Pont Merck Pharmaceutical Company Aminomethyl oxooxazolidinyl aroylbenzene derivatives useful as antibacterial agents
ES2059467T3 (es) * 1987-10-21 1994-11-16 Du Pont Merck Pharma Derivados de aminometil-oxooxazolidinil-etenilbenceno utiles como agentes antibacterianos.
US4948801A (en) * 1988-07-29 1990-08-14 E. I. Du Pont De Nemours And Company Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents
DE68929303T2 (de) * 1988-09-15 2002-05-02 Upjohn Co 3-(Stickstoff substituierte)phenyl-5-beta-amidomethyloxazoliden-2-one
WO1993009103A1 (en) * 1991-11-01 1993-05-13 The Upjohn Company Substituted aryl- and heteroarylphenyloxazolidinones useful as antibacterial agents
SK283420B6 (sk) * 1992-05-08 2003-07-01 Pharmacia & Upjohn Company Antimikrobiálne oxazolidinóny obsahujúce substituované diazínové skupiny
MY115155A (en) * 1993-09-09 2003-04-30 Upjohn Co Substituted oxazine and thiazine oxazolidinone antimicrobials.
EP0730591B1 (en) * 1993-11-22 1999-07-14 PHARMACIA & UPJOHN COMPANY Esters of substituted-hydroxyacetyl piperazine phenyl oxazolidinones
US5668286A (en) * 1994-03-15 1997-09-16 Pharmacia & Upjohn Company Oxazolidinone derivatives and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
MX9703543A (es) 1997-08-30
AU3889095A (en) 1996-06-06
CN1046520C (zh) 1999-11-17
NZ295528A (en) 1999-03-29
ATE233766T1 (de) 2003-03-15
DE69529838T2 (de) 2003-11-13
EP0792273B1 (en) 2003-03-05
US5952324A (en) 1999-09-14
WO1996015130A1 (en) 1996-05-23
DE69529838D1 (de) 2003-04-10
EP0792273A1 (en) 1997-09-03
AU702733B2 (en) 1999-03-04
NO972222D0 (no) 1997-05-14
PT792273E (pt) 2003-06-30
JPH10508844A (ja) 1998-09-02
DK0792273T3 (da) 2003-06-16
ES2193201T3 (es) 2003-11-01
RU2128660C1 (ru) 1999-04-10
BR9509673A (pt) 1997-09-30
CN1163615A (zh) 1997-10-29
KR100392216B1 (ko) 2003-10-17

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application