NO970155L - Kunstig ekstracellulær biologisk matrise samt fremgangsmåte ved fremstilling derav - Google Patents
Kunstig ekstracellulær biologisk matrise samt fremgangsmåte ved fremstilling deravInfo
- Publication number
- NO970155L NO970155L NO970155A NO970155A NO970155L NO 970155 L NO970155 L NO 970155L NO 970155 A NO970155 A NO 970155A NO 970155 A NO970155 A NO 970155A NO 970155 L NO970155 L NO 970155L
- Authority
- NO
- Norway
- Prior art keywords
- matrix
- peptide fragment
- nerve
- cell adhesive
- adhesive peptide
- Prior art date
Links
- 239000011159 matrix material Substances 0.000 title abstract 7
- 108010033276 Peptide Fragments Proteins 0.000 abstract 4
- 102000007079 Peptide Fragments Human genes 0.000 abstract 4
- 230000004956 cell adhesive effect Effects 0.000 abstract 4
- 210000005036 nerve Anatomy 0.000 abstract 4
- 239000000017 hydrogel Substances 0.000 abstract 3
- 229920000936 Agarose Polymers 0.000 abstract 2
- 108010037362 Extracellular Matrix Proteins Proteins 0.000 abstract 2
- 102000010834 Extracellular Matrix Proteins Human genes 0.000 abstract 2
- 239000012528 membrane Substances 0.000 abstract 2
- XQQUSYWGKLRJRA-RABCQHRBSA-N (2s)-2-[[(2s)-2-[[(2s)-2-[[(2s)-6-amino-2-[[(2s,3s)-2-amino-3-methylpentanoyl]amino]hexanoyl]amino]-3-methylbutanoyl]amino]propanoyl]amino]-3-methylbutanoic acid Chemical compound CC[C@H](C)[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(O)=O XQQUSYWGKLRJRA-RABCQHRBSA-N 0.000 abstract 1
- MWOGMBZGFFZBMK-LJZWMIMPSA-N (2s)-2-[[(2s)-2-[[2-[[(2s,3s)-2-[[(2s)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]acetyl]amino]-3-hydroxypropanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid Chemical compound NC(N)=NCCC[C@@H](C(O)=O)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@@H](N)CC1=CC=C(O)C=C1 MWOGMBZGFFZBMK-LJZWMIMPSA-N 0.000 abstract 1
- IYMAXBFPHPZYIK-BQBZGAKWSA-N Arg-Gly-Asp Chemical compound NC(N)=NCCC[C@H](N)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(O)=O IYMAXBFPHPZYIK-BQBZGAKWSA-N 0.000 abstract 1
- 239000000853 adhesive Substances 0.000 abstract 1
- 230000001070 adhesive effect Effects 0.000 abstract 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 108010072041 arginyl-glycyl-aspartic acid Proteins 0.000 abstract 1
- 210000000845 cartilage Anatomy 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 210000001612 chondrocyte Anatomy 0.000 abstract 1
- 210000002744 extracellular matrix Anatomy 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 230000009545 invasion Effects 0.000 abstract 1
- 108010088381 isoleucyl-lysyl-valyl-alanyl-valine Proteins 0.000 abstract 1
- 210000000056 organ Anatomy 0.000 abstract 1
- 239000011148 porous material Substances 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 230000001172 regenerating effect Effects 0.000 abstract 1
- 210000002435 tendon Anatomy 0.000 abstract 1
- 210000001519 tissue Anatomy 0.000 abstract 1
- 230000017423 tissue regeneration Effects 0.000 abstract 1
- 108010052768 tyrosyl-isoleucyl-glycyl-seryl-arginine Proteins 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/20—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/52—Hydrogels or hydrocolloids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/005—Ingredients of undetermined constitution or reaction products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
- A61L31/043—Proteins; Polypeptides; Degradation products thereof
- A61L31/047—Other specific proteins or polypeptides not covered by A61L31/044 - A61L31/046
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/32—Materials or treatment for tissue regeneration for nerve reconstruction
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
- Y10S530/812—Peptides or proteins is immobilized on, or in, an organic carrier
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
- Y10S530/812—Peptides or proteins is immobilized on, or in, an organic carrier
- Y10S530/813—Carrier is a saccharide
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Dermatology (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Engineering & Computer Science (AREA)
- Vascular Medicine (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Heart & Thoracic Surgery (AREA)
- Surgery (AREA)
- Botany (AREA)
- Cell Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Dispersion Chemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Immunology (AREA)
- Materials For Medical Uses (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/280,646 US5834029A (en) | 1994-07-20 | 1994-07-20 | Nerve guidance channel containing bioartificial three-dimensional hydrogel extracellular matrix derivatized with cell adhesive peptide fragment |
PCT/US1995/009282 WO1996002286A1 (fr) | 1994-07-20 | 1995-07-20 | Compositions et procedes pour former une matrice extra-cellulaire bioartificielle |
Publications (2)
Publication Number | Publication Date |
---|---|
NO970155D0 NO970155D0 (no) | 1997-01-14 |
NO970155L true NO970155L (no) | 1997-03-19 |
Family
ID=23073997
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO970155A NO970155L (no) | 1994-07-20 | 1997-01-14 | Kunstig ekstracellulær biologisk matrise samt fremgangsmåte ved fremstilling derav |
Country Status (14)
Country | Link |
---|---|
US (2) | US5834029A (fr) |
EP (1) | EP0772466B1 (fr) |
JP (1) | JPH10503098A (fr) |
KR (1) | KR970704481A (fr) |
AT (1) | ATE255425T1 (fr) |
AU (1) | AU3142395A (fr) |
CA (1) | CA2194493A1 (fr) |
DE (1) | DE69532240D1 (fr) |
FI (1) | FI970218A (fr) |
IL (1) | IL114672A (fr) |
NO (1) | NO970155L (fr) |
TR (2) | TR199500883A2 (fr) |
WO (1) | WO1996002286A1 (fr) |
ZA (1) | ZA956033B (fr) |
Families Citing this family (144)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5834029A (en) * | 1994-07-20 | 1998-11-10 | Cytotherapeutics, Inc. | Nerve guidance channel containing bioartificial three-dimensional hydrogel extracellular matrix derivatized with cell adhesive peptide fragment |
US6294202B1 (en) * | 1994-10-06 | 2001-09-25 | Genzyme Corporation | Compositions containing polyanionic polysaccharides and hydrophobic bioabsorbable polymers |
US20050152950A1 (en) * | 1995-11-13 | 2005-07-14 | Saffran Bruce N. | Method and apparatus for macromolecular delivery using a coated membrane |
SE9601243D0 (sv) * | 1996-03-29 | 1996-03-29 | Hans Arne Hansson | Promotion of regeneration of organized tissues |
IL118376A0 (en) * | 1996-05-22 | 1996-09-12 | Univ Ben Gurion | Polysaccharide sponges for cell culture and transplantation |
SE9602879D0 (sv) * | 1996-07-26 | 1996-07-26 | Henrich Cheng | Medical device |
US6238429B1 (en) * | 1997-05-05 | 2001-05-29 | Medtronic, Inc. | Biologic cabling |
JP4988076B2 (ja) * | 1997-05-22 | 2012-08-01 | マイヤー,ヤールク | ペプチド被覆インプラントおよびその調製方法 |
WO1999047186A1 (fr) * | 1998-03-18 | 1999-09-23 | University Of Pittsburgh | Matieres composites a base de chitosane contenant du glycosaminoglycane pour la reparation du cartilage |
US6171610B1 (en) * | 1998-04-24 | 2001-01-09 | University Of Massachusetts | Guided development and support of hydrogel-cell compositions |
US6027744A (en) * | 1998-04-24 | 2000-02-22 | University Of Massachusetts Medical Center | Guided development and support of hydrogel-cell compositions |
US6593133B1 (en) * | 1998-07-06 | 2003-07-15 | Nsgene A/S | Neurotrophic factors |
US6592623B1 (en) | 1999-08-31 | 2003-07-15 | Virginia Commonwealth University Intellectual Property Foundation | Engineered muscle |
US6903244B1 (en) | 1999-02-26 | 2005-06-07 | University Of Utah Research Foundation | Mice which are +/− or −/− for the elastin gene as models for vascular disease |
US7575921B2 (en) * | 1999-12-30 | 2009-08-18 | Vbi Technologies, L.L.C. | Spore-like cells and uses thereof |
US7560275B2 (en) * | 1999-12-30 | 2009-07-14 | Vbi Technologies, L.L.C. | Compositions and methods for generating skin |
DE10026789B4 (de) * | 2000-05-31 | 2004-09-02 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Knorpelersatz und Verfahren zu dessen Herstellung |
JP2002078792A (ja) * | 2000-09-07 | 2002-03-19 | Kuraray Co Ltd | 神経再生用材料 |
DE10053611A1 (de) * | 2000-10-28 | 2002-05-02 | Inst Textil & Faserforschung | Bioresorbierbare Nervenleitschiene |
US20020151050A1 (en) * | 2000-10-30 | 2002-10-17 | Vacanti Charles A. | Isolation of spore-like cells from tissues exposed to extreme conditions |
EP1339349A4 (fr) * | 2000-11-14 | 2007-07-04 | R Labs Inc Nv | Gels de laminine et d'acide hyaluronique reticule et leur utilisation dans la culture cellulaire et les implants medicaux |
US7442370B2 (en) | 2001-02-01 | 2008-10-28 | Biogen Idec Ma Inc. | Polymer conjugates of mutated neublastin |
US20050192228A1 (en) * | 2001-02-05 | 2005-09-01 | Jean Rapin | Tripeptide derivatives for the treatment of neurodegenerative diseases |
DE10105040A1 (de) * | 2001-02-05 | 2002-08-14 | Tell Pharm Ag Hergiswil | Tripeptid-Derivate für die Behandlung von postläsionalen Krankheiten des Nervensystems |
DE10105038B4 (de) * | 2001-02-05 | 2005-07-07 | Neurotell Ag | Tripeptid-Derivate für die Behandlung von postläsionalen Krankheiten des Nervensystems |
DE10105041A1 (de) * | 2001-02-05 | 2002-08-14 | Tell Pharm Ag Hergiswil | Tripeptide und Tripeptid-Derivate für die Behandlung neurodegenerativer Krankheiten |
WO2002062961A2 (fr) * | 2001-02-06 | 2002-08-15 | Massachusetts Institute Of Technology | Encapsulation en echafaudage peptidique de cellules tissulaires, et utilisations |
US7276580B2 (en) | 2001-03-12 | 2007-10-02 | Biogen Idec Ma Inc. | Neurotrophic factors |
US20040151705A1 (en) * | 2002-03-22 | 2004-08-05 | Shuichi Mizuno | Neo-cartilage constructs and a method for preparation thereof |
JP3871525B2 (ja) * | 2001-04-26 | 2007-01-24 | ニプロ株式会社 | 生体組織または器官再生用器具 |
US20030049839A1 (en) * | 2001-08-01 | 2003-03-13 | The University Of Texas System | Transparent multi-channel cell scaffold that creates a cellular and/or molecular gradient |
US6716225B2 (en) * | 2001-08-02 | 2004-04-06 | Collagen Matrix, Inc. | Implant devices for nerve repair |
WO2003030836A2 (fr) * | 2001-10-12 | 2003-04-17 | Case Western Reserve University | Regeneration neuronale |
US7041506B2 (en) * | 2001-11-19 | 2006-05-09 | Becton Dickinson And Company | Peptides promoting cell adherence, growth and secretion |
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AU2002362052A1 (en) * | 2001-12-04 | 2003-06-17 | The Trustees Of The University Of Pennsylvania | Device and method using integrated neuronal cells and an electronic device |
KR100493461B1 (ko) * | 2002-02-27 | 2005-06-07 | 재단법인서울대학교산학협력재단 | 접착분자가 부착된 천연고분자, 그의 제조방법 및 그의 용도 |
US8298606B2 (en) * | 2002-03-08 | 2012-10-30 | The Regents Of The University Of California | Methods and compositions for stabilizing the myocardium |
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US20070100358A2 (en) * | 2002-08-01 | 2007-05-03 | Texas Scottish Rite Hospital For Children | A Biomimetic Synthetic Nerve Implant |
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US8545386B2 (en) | 2003-08-14 | 2013-10-01 | Boston Scientific Scimed, Inc. | Surgical slings |
WO2005020677A1 (fr) | 2003-08-29 | 2005-03-10 | The Walter And Eliza Hall Institute Of Medical Research | Procede de selection de modeles d'animaux parmi les animaux ayant ete soumis a la mutagenese, et utilisation de facteurs de transcription myb pour le criblage |
US20070148129A1 (en) | 2003-12-24 | 2007-06-28 | The Walter And Eliza Hall Instiute Of Medical Research | Therapeutic agents and uses therefor |
US7709439B2 (en) * | 2004-02-20 | 2010-05-04 | Boston Scientific Scimed, Inc. | Biomaterials for enhanced healing |
US7840263B2 (en) | 2004-02-27 | 2010-11-23 | Cardiac Pacemakers, Inc. | Method and apparatus for device controlled gene expression |
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US20060134779A1 (en) * | 2004-03-10 | 2006-06-22 | Banes Albert J | Modulation of cell intrinsic strain to control cell modulus, matrix synthesis, secretion, organization, material properties and remodeling of tissue engineered constructs |
WO2005099758A2 (fr) * | 2004-04-17 | 2005-10-27 | The Board Of Trustees The Leland Standford Junior University | Matrice de tissu bioartificielle injectable |
US8741635B2 (en) | 2004-05-12 | 2014-06-03 | The Walter And Eliza Hall Institute Of Medical Research | Method of cell isolation |
US7764995B2 (en) | 2004-06-07 | 2010-07-27 | Cardiac Pacemakers, Inc. | Method and apparatus to modulate cellular regeneration post myocardial infarct |
US8071131B2 (en) * | 2004-07-15 | 2011-12-06 | Ivoclar Vivadent, Inc. | Mineralizing composite materials for restoring teeth |
EP2238983B1 (fr) | 2004-08-19 | 2014-07-23 | Biogen Idec MA Inc. | Variantes de la neuroblastine |
JP4959566B2 (ja) * | 2004-08-19 | 2012-06-27 | バイオジェン・アイデック・エムエイ・インコーポレイテッド | トランスホーミング増殖因子βファミリータンパク質の折りたたみ |
US8106014B2 (en) * | 2004-09-14 | 2012-01-31 | Neurotex Limited | Methods and apparatus for enhanced growth of peripheral nerves and nervous tissue |
US20060079927A1 (en) * | 2004-10-08 | 2006-04-13 | Medtronic Vascular, Inc., A Delaware Corporation | Detachable joint catheter and method |
US7235592B2 (en) | 2004-10-12 | 2007-06-26 | Zimmer Gmbh | PVA hydrogel |
JP5674256B2 (ja) * | 2004-12-08 | 2015-02-25 | シャイア リジェネラティブ メディシン, インコーポレイテッド | 細胞含有流動性組成物の最小侵襲投与のための材料および方法 |
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1994
- 1994-07-20 US US08/280,646 patent/US5834029A/en not_active Expired - Lifetime
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1995
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- 1995-07-20 AT AT95927374T patent/ATE255425T1/de not_active IP Right Cessation
- 1995-07-20 AU AU31423/95A patent/AU3142395A/en not_active Abandoned
- 1995-07-20 TR TR95/00883A patent/TR199500883A2/xx unknown
- 1995-07-20 KR KR1019970700282A patent/KR970704481A/ko not_active Application Discontinuation
- 1995-07-20 JP JP8505272A patent/JPH10503098A/ja active Pending
- 1995-07-20 WO PCT/US1995/009282 patent/WO1996002286A1/fr active IP Right Grant
- 1995-07-20 EP EP95927374A patent/EP0772466B1/fr not_active Expired - Lifetime
- 1995-07-20 CA CA002194493A patent/CA2194493A1/fr not_active Abandoned
- 1995-07-20 DE DE69532240T patent/DE69532240D1/de not_active Expired - Lifetime
- 1995-08-20 TR TR95/00884A patent/TR199500884A2/xx unknown
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- 1997-01-14 NO NO970155A patent/NO970155L/no not_active Application Discontinuation
- 1997-01-17 FI FI970218A patent/FI970218A/fi unknown
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FI970218A0 (fi) | 1997-01-17 |
TR199500883A2 (tr) | 1996-06-21 |
TR199500884A2 (tr) | 1996-06-21 |
JPH10503098A (ja) | 1998-03-24 |
FI970218A (fi) | 1997-03-17 |
ATE255425T1 (de) | 2003-12-15 |
AU3142395A (en) | 1996-02-16 |
DE69532240D1 (de) | 2004-01-15 |
NO970155D0 (no) | 1997-01-14 |
EP0772466B1 (fr) | 2003-12-03 |
WO1996002286A1 (fr) | 1996-02-01 |
EP0772466A1 (fr) | 1997-05-14 |
ZA956033B (en) | 1996-03-11 |
IL114672A (en) | 2000-12-06 |
US6156572A (en) | 2000-12-05 |
CA2194493A1 (fr) | 1996-02-01 |
IL114672A0 (en) | 1995-11-27 |
KR970704481A (ko) | 1997-09-06 |
US5834029A (en) | 1998-11-10 |
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