NO965353L - 3-amino-2-okso-1-piperidineddiksyrederivater som enzyminhibitorer - Google Patents
3-amino-2-okso-1-piperidineddiksyrederivater som enzyminhibitorerInfo
- Publication number
- NO965353L NO965353L NO965353A NO965353A NO965353L NO 965353 L NO965353 L NO 965353L NO 965353 A NO965353 A NO 965353A NO 965353 A NO965353 A NO 965353A NO 965353 L NO965353 L NO 965353L
- Authority
- NO
- Norway
- Prior art keywords
- carbon atoms
- alkyl
- atoms
- ring
- amino
- Prior art date
Links
- 239000002253 acid Substances 0.000 title 1
- 239000002532 enzyme inhibitor Substances 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 12
- 125000000217 alkyl group Chemical group 0.000 abstract 5
- 125000003545 alkoxy group Chemical group 0.000 abstract 3
- -1 eimino Chemical group 0.000 abstract 3
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- 125000005842 heteroatom Chemical group 0.000 abstract 2
- 125000006413 ring segment Chemical group 0.000 abstract 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 108090000190 Thrombin Proteins 0.000 abstract 1
- 208000007536 Thrombosis Diseases 0.000 abstract 1
- 230000002159 abnormal effect Effects 0.000 abstract 1
- 150000001299 aldehydes Chemical class 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 125000000592 heterocycloalkyl group Chemical group 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
- 229960004072 thrombin Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/05—Dipeptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Hydrogenated Pyridines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26137894A | 1994-06-17 | 1994-06-17 | |
| US35683194A | 1994-12-13 | 1994-12-13 | |
| US48700795A | 1995-06-07 | 1995-06-07 | |
| PCT/US1995/007661 WO1995035311A1 (en) | 1994-06-17 | 1995-06-19 | 3-amino-2-oxo-1-piperidineacetic derivatives as enzyme inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO965353D0 NO965353D0 (no) | 1996-12-13 |
| NO965353L true NO965353L (no) | 1997-02-17 |
Family
ID=27401400
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO965353A NO965353L (no) | 1994-06-17 | 1996-12-13 | 3-amino-2-okso-1-piperidineddiksyrederivater som enzyminhibitorer |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0802923A1 (de) |
| CN (1) | CN1151166A (de) |
| AU (1) | AU700808B2 (de) |
| BR (1) | BR9508048A (de) |
| CA (1) | CA2192210A1 (de) |
| MX (1) | MX9606566A (de) |
| NO (1) | NO965353L (de) |
| NZ (1) | NZ288940A (de) |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4192875A (en) * | 1979-02-02 | 1980-03-11 | Merck & Co., Inc. | Cyclic hexapeptide |
-
1995
- 1995-06-19 EP EP95923922A patent/EP0802923A1/de not_active Withdrawn
- 1995-06-19 CN CN95193661A patent/CN1151166A/zh active Pending
- 1995-06-19 AU AU28630/95A patent/AU700808B2/en not_active Ceased
- 1995-06-19 NZ NZ288940A patent/NZ288940A/xx unknown
- 1995-06-19 BR BR9508048A patent/BR9508048A/pt not_active Application Discontinuation
- 1995-06-19 MX MX9606566A patent/MX9606566A/es unknown
- 1995-06-19 CA CA002192210A patent/CA2192210A1/en not_active Abandoned
-
1996
- 1996-12-13 NO NO965353A patent/NO965353L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2863095A (en) | 1996-01-15 |
| BR9508048A (pt) | 1997-11-18 |
| AU700808B2 (en) | 1999-01-14 |
| CN1151166A (zh) | 1997-06-04 |
| EP0802923A1 (de) | 1997-10-29 |
| NZ288940A (en) | 1999-01-28 |
| NO965353D0 (no) | 1996-12-13 |
| MX9606566A (es) | 1997-07-31 |
| CA2192210A1 (en) | 1995-12-28 |
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